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The map label for this gene is ephD [H]

Identifier: 41409380

GI number: 41409380

Start: 3642272

End: 3643201

Strand: Reverse

Name: ephD [H]

Synonym: MAP3282c

Alternate gene names: 41409380

Gene position: 3643201-3642272 (Counterclockwise)

Preceding gene: 41409381

Following gene: 41409379

Centisome position: 75.43

GC content: 70.11

Gene sequence:

>930_bases
ATGACCACCGAAGTGGCCTCCACCACGGTCACCGCCACCGACGGCGTGCGACTGGCGGTGCACACCTACACCGGGATCGA
CCCCGCACGGCCGACCGTCCTGGCCATCCACGGCTATCCCGACAACCACCACGTGTGGGACGGGGTGGCCGGGGTGCTGC
GCCGCCGTTTCAACGTGGTGGCCTACGACGTGCGCGGCGCGGGCCAATCGTCAACGCCGCCAGAGCGTTCCGGCTACCGG
CTGGATCAGCTGGTCGCCGACGTCGACGCGGTGATCGGCCGGCTCGGCGTGGACAGCGTGCACCTGCTGGCCCACGACTG
GGGCTCCATCCAGGGCTGGGCGGCGGTCACCGACGAGTCGGTGATGGGCAAGATCGCCTCGTTCACCTCGATCTCCGGCC
CGCACCTGAACTACGCCGGCCGGTTCCTGCGCTCGGCGCGCACGCCGGGCGGCGTCCTCGACGTCGTCAAGCAGATCCTG
GCGTCGTCCTACATCTGGTTCTTTTTGGCCCCGAGTGCGCCGGAGTGGGCGATCCGGTCTGGGGCGACGGTGAAAGTCTT
TGAGGCCGTTGAACGTATCGGCGGCTCGACCGCCGGCGCCCAGCGGGGAGCCGGGTACCGGTCGACCGACGACTACCTCA
ACGGGCTCAACCTTTACCGGGCGAACATGCCGGGACCGATCCTGTCGCCGCCGGCGCGGCTGCCGCAGACCTCGGTTCCG
GTGCAGGTGATCGTCGCGCGCCGGGACTACTTCGTATCGCCTGCCCTGCAACGGTTCACCGGCTCCATCCCGGACGGCAG
CCGGGTCGTCCCGATCGACGGCGGACACTGGGTGGTCAACTCCCATCCCGACGTCATCGCCCGGCTCACCGGCGACTGGG
TCGACCTGACGACGCGGCCGGCGGGCGGCCACCACACGGGACAGACGTGA

Upstream 100 bases:

>100_bases
CGTACTACACGCCGGGCTTTCACCCGTCCCAGCTGGGCGGGGTGGGGCGCGCCGTCGACTACCTGGCCCGCTCACCGGCC
GCCCGGGCCGCGCACTGACC

Downstream 100 bases:

>100_bases
GGATGACTATGGCACAAGCGATTTGGGAAAACATTCCGGCCGACCTGTACGGCCGCCGCAAACGCGACCGGATGTACACG
GCGTTGTACGGCGTGGGTGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTTEVASTTVTATDGVRLAVHTYTGIDPARPTVLAIHGYPDNHHVWDGVAGVLRRRFNVVAYDVRGAGQSSTPPERSGYR
LDQLVADVDAVIGRLGVDSVHLLAHDWGSIQGWAAVTDESVMGKIASFTSISGPHLNYAGRFLRSARTPGGVLDVVKQIL
ASSYIWFFLAPSAPEWAIRSGATVKVFEAVERIGGSTAGAQRGAGYRSTDDYLNGLNLYRANMPGPILSPPARLPQTSVP
VQVIVARRDYFVSPALQRFTGSIPDGSRVVPIDGGHWVVNSHPDVIARLTGDWVDLTTRPAGGHHTGQT

Sequences:

>Translated_309_residues
MTTEVASTTVTATDGVRLAVHTYTGIDPARPTVLAIHGYPDNHHVWDGVAGVLRRRFNVVAYDVRGAGQSSTPPERSGYR
LDQLVADVDAVIGRLGVDSVHLLAHDWGSIQGWAAVTDESVMGKIASFTSISGPHLNYAGRFLRSARTPGGVLDVVKQIL
ASSYIWFFLAPSAPEWAIRSGATVKVFEAVERIGGSTAGAQRGAGYRSTDDYLNGLNLYRANMPGPILSPPARLPQTSVP
VQVIVARRDYFVSPALQRFTGSIPDGSRVVPIDGGHWVVNSHPDVIARLTGDWVDLTTRPAGGHHTGQT
>Mature_308_residues
TTEVASTTVTATDGVRLAVHTYTGIDPARPTVLAIHGYPDNHHVWDGVAGVLRRRFNVVAYDVRGAGQSSTPPERSGYRL
DQLVADVDAVIGRLGVDSVHLLAHDWGSIQGWAAVTDESVMGKIASFTSISGPHLNYAGRFLRSARTPGGVLDVVKQILA
SSYIWFFLAPSAPEWAIRSGATVKVFEAVERIGGSTAGAQRGAGYRSTDDYLNGLNLYRANMPGPILSPPARLPQTSVPV
QVIVARRDYFVSPALQRFTGSIPDGSRVVPIDGGHWVVNSHPDVIARLTGDWVDLTTRPAGGHHTGQT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=298, Percent_Identity=24.8322147651007, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI218777840, Length=273, Percent_Identity=25.6410256410256, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI13376164, Length=273, Percent_Identity=25.6410256410256, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17562298, Length=296, Percent_Identity=25.3378378378378, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17554012, Length=195, Percent_Identity=28.2051282051282, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00106 adh_short [H]

EC number: NA

Molecular weight: Translated: 33095; Mature: 32963

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTEVASTTVTATDGVRLAVHTYTGIDPARPTVLAIHGYPDNHHVWDGVAGVLRRRFNVV
CCCCCCCEEEEECCCEEEEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCEE
AYDVRGAGQSSTPPERSGYRLDQLVADVDAVIGRLGVDSVHLLAHDWGSIQGWAAVTDES
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECCHH
VMGKIASFTSISGPHLNYAGRFLRSARTPGGVLDVVKQILASSYIWFFLAPSAPEWAIRS
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHCC
GATVKVFEAVERIGGSTAGAQRGAGYRSTDDYLNGLNLYRANMPGPILSPPARLPQTSVP
CCEEHHHHHHHHHCCCCCCHHCCCCCCCCHHHHCCCEEEECCCCCCCCCCCCCCCCCCCC
VQVIVARRDYFVSPALQRFTGSIPDGSRVVPIDGGHWVVNSHPDVIARLTGDWVDLTTRP
EEEEEECCCHHCCHHHHHHCCCCCCCCEEEEECCCEEEECCCCCEEEEECCCEEEEECCC
AGGHHTGQT
CCCCCCCCC
>Mature Secondary Structure 
TTEVASTTVTATDGVRLAVHTYTGIDPARPTVLAIHGYPDNHHVWDGVAGVLRRRFNVV
CCCCCCEEEEECCCEEEEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCEE
AYDVRGAGQSSTPPERSGYRLDQLVADVDAVIGRLGVDSVHLLAHDWGSIQGWAAVTDES
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECCHH
VMGKIASFTSISGPHLNYAGRFLRSARTPGGVLDVVKQILASSYIWFFLAPSAPEWAIRS
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHCC
GATVKVFEAVERIGGSTAGAQRGAGYRSTDDYLNGLNLYRANMPGPILSPPARLPQTSVP
CCEEHHHHHHHHHCCCCCCHHCCCCCCCCHHHHCCCEEEECCCCCCCCCCCCCCCCCCCC
VQVIVARRDYFVSPALQRFTGSIPDGSRVVPIDGGHWVVNSHPDVIARLTGDWVDLTTRP
EEEEEECCCHHCCHHHHHHCCCCCCCCEEEEECCCEEEECCCCCEEEEECCCEEEEECCC
AGGHHTGQT
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]