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The map label for this gene is mshA [H]

Identifier: 41409344

GI number: 41409344

Start: 3601698

End: 3602939

Strand: Direct

Name: mshA [H]

Synonym: MAP3246

Alternate gene names: 41409344

Gene position: 3601698-3602939 (Clockwise)

Preceding gene: 41409343

Following gene: 41409346

Centisome position: 74.57

GC content: 74.07

Gene sequence:

>1242_bases
ATGAGCAGGGAAGGAACCCGCATGAGAATCGCGATGATCTCCGAACACGCCAGCCCGCTGGCACATTTGGGCGGCGTGGA
CGCGGGCGGACAGAACGTCCACGTCGCCGAGCTGTCCTGCGCGCTGGCGCGGCGCGGCCACGACGTGGTGGTCTACACGC
GCCGCGACGACCCGCGGCTTCCCGACTCGGTCGACACCCCGCACGGCTACAGCGTGGTGCACGTGCCGGCGGGACCGGCG
CGGGTGCTGCCCAAAGACGAGTTGCTGCAATACATGTACGGCTTCGCGCAGTTCCTGCGCCAGCAGTGGTGCTCGGACGG
GCCCGATGTGGCCCATGCGCACTTCTGGATGTCGGGGGTGGCCACCCAGCGGGCCGCCCGCGCGCATTCGATACCGACCG
TGCAGACCTTCCACGCGCTCGGGCTGACCAAGCGGCTGCACCAGGGCAGCGAGGACACCAGCCCGGACTGCCGGATCGAC
GTGGAAGCCCGGGTCGCCCGGGAAGCCGACTGGGTGGCGGCCACCAGCACCGACGAGGTCTTCGAGCTGGTGCGCATGGG
CCGGGCCCGATCCCGCACCTCGGTGGTGCCGTGCGGAGTGGACCTCGACGCGTTCACCCCCGACGGCCCCGTCGCTGCCC
GCGGTGCGCGGCCGCGCATCGTCACGGTGGGACGGCTGGTGCCGCGCAAGGGTTTTGACACCATCGTGCGCGCCCTGCCC
CGCATCCCGGACGCCGAGTTGGTGATCGTGGGCGGGCCGCCGGCGGCCGAACTGGCCGGCGACGAGCAGGCGCGGCGGCT
GCAACGACTGACCGGCGAGCTCGGCGTCGCCGACCGGGTGCGGCTGCTGGGCGGGGTCACCCGCGCGCAGATGCCGGCGT
TGCTGCGCTCGGCCGACGTGGTGGCCTGCACGCCGTGGTACGAGCCGTTCGGCATCGTGCCGCTGGAAGCCATGGCCTGC
GGGGTCCCGGTGGTGGCCACGGCGGTGGGCGGGATCCGCGACACCGTCGTCGACGGCGCCACCGGCCGGCTGGTGCCGCC
CAAGGACCCGGACGCTCTGGGTGAGGCCGTCGCCGCCCTGCTTCGCGACGGCCGCCGCGGCCGGACGCTGGGCGAGGCCG
GGCGGGAGCGGGCCCGGGCCCGCTACAGCTGGGACCGGGTGGCGGCCGACACCGAACGCATCTACGAACGGCTGTCCCCC
GCCCGGCGCGGGGTCGGCACCCCGAGCACGCGATCCGGGTGA

Upstream 100 bases:

>100_bases
CGGTGGCCGCCGGCAAGGCCGCCCGGGACTTCGCCACCGCCCGGTTCGGACTCAAACGCTTTCTGGCCGACTGGGACCAA
GTGATCGGGGAGCTGTGCAG

Downstream 100 bases:

>100_bases
TCTTGTGGCTCAACCACTTTCCAGCATCCGCAGCGAACGCTCGACGGCATCGGGCAGCCGCCGGCGTTCCCGCAGCGCGG
CCGGCAACGCCGCCGTCGCC

Product: hypothetical protein

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase [H]

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MSREGTRMRIAMISEHASPLAHLGGVDAGGQNVHVAELSCALARRGHDVVVYTRRDDPRLPDSVDTPHGYSVVHVPAGPA
RVLPKDELLQYMYGFAQFLRQQWCSDGPDVAHAHFWMSGVATQRAARAHSIPTVQTFHALGLTKRLHQGSEDTSPDCRID
VEARVAREADWVAATSTDEVFELVRMGRARSRTSVVPCGVDLDAFTPDGPVAARGARPRIVTVGRLVPRKGFDTIVRALP
RIPDAELVIVGGPPAAELAGDEQARRLQRLTGELGVADRVRLLGGVTRAQMPALLRSADVVACTPWYEPFGIVPLEAMAC
GVPVVATAVGGIRDTVVDGATGRLVPPKDPDALGEAVAALLRDGRRGRTLGEAGRERARARYSWDRVAADTERIYERLSP
ARRGVGTPSTRSG

Sequences:

>Translated_413_residues
MSREGTRMRIAMISEHASPLAHLGGVDAGGQNVHVAELSCALARRGHDVVVYTRRDDPRLPDSVDTPHGYSVVHVPAGPA
RVLPKDELLQYMYGFAQFLRQQWCSDGPDVAHAHFWMSGVATQRAARAHSIPTVQTFHALGLTKRLHQGSEDTSPDCRID
VEARVAREADWVAATSTDEVFELVRMGRARSRTSVVPCGVDLDAFTPDGPVAARGARPRIVTVGRLVPRKGFDTIVRALP
RIPDAELVIVGGPPAAELAGDEQARRLQRLTGELGVADRVRLLGGVTRAQMPALLRSADVVACTPWYEPFGIVPLEAMAC
GVPVVATAVGGIRDTVVDGATGRLVPPKDPDALGEAVAALLRDGRRGRTLGEAGRERARARYSWDRVAADTERIYERLSP
ARRGVGTPSTRSG
>Mature_412_residues
SREGTRMRIAMISEHASPLAHLGGVDAGGQNVHVAELSCALARRGHDVVVYTRRDDPRLPDSVDTPHGYSVVHVPAGPAR
VLPKDELLQYMYGFAQFLRQQWCSDGPDVAHAHFWMSGVATQRAARAHSIPTVQTFHALGLTKRLHQGSEDTSPDCRIDV
EARVAREADWVAATSTDEVFELVRMGRARSRTSVVPCGVDLDAFTPDGPVAARGARPRIVTVGRLVPRKGFDTIVRALPR
IPDAELVIVGGPPAAELAGDEQARRLQRLTGELGVADRVRLLGGVTRAQMPALLRSADVVACTPWYEPFGIVPLEAMACG
VPVVATAVGGIRDTVVDGATGRLVPPKDPDALGEAVAALLRDGRRGRTLGEAGRERARARYSWDRVAADTERIYERLSPA
RRGVGTPSTRSG

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Homo sapiens, GI11863130, Length=407, Percent_Identity=27.027027027027, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI14861836, Length=214, Percent_Identity=30.3738317757009, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17532709, Length=400, Percent_Identity=24.75, Blast_Score=88, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI9755344, Length=408, Percent_Identity=25.4901960784314, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357469, Length=157, Percent_Identity=36.3057324840764, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24654571, Length=333, Percent_Identity=27.027027027027, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814
- InterPro:   IPR013534 [H]

Pfam domain/function: PF08323 Glyco_transf_5; PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 44485; Mature: 44354

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSREGTRMRIAMISEHASPLAHLGGVDAGGQNVHVAELSCALARRGHDVVVYTRRDDPRL
CCCCCCEEEEEEHHHCCCHHHHHCCCCCCCCEEEHHHHHHHHHHCCCEEEEEEECCCCCC
PDSVDTPHGYSVVHVPAGPARVLPKDELLQYMYGFAQFLRQQWCSDGPDVAHAHFWMSGV
CCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ATQRAARAHSIPTVQTFHALGLTKRLHQGSEDTSPDCRIDVEARVAREADWVAATSTDEV
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHCCCCCEEECCHHHH
FELVRMGRARSRTSVVPCGVDLDAFTPDGPVAARGARPRIVTVGRLVPRKGFDTIVRALP
HHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHC
RIPDAELVIVGGPPAAELAGDEQARRLQRLTGELGVADRVRLLGGVTRAQMPALLRSADV
CCCCCCEEEECCCCHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCE
VACTPWYEPFGIVPLEAMACGVPVVATAVGGIRDTVVDGATGRLVPPKDPDALGEAVAAL
EEECCCCCCCCCCCHHHHHCCCHHHHHHHCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
LRDGRRGRTLGEAGRERARARYSWDRVAADTERIYERLSPARRGVGTPSTRSG
HHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SREGTRMRIAMISEHASPLAHLGGVDAGGQNVHVAELSCALARRGHDVVVYTRRDDPRL
CCCCCEEEEEEHHHCCCHHHHHCCCCCCCCEEEHHHHHHHHHHCCCEEEEEEECCCCCC
PDSVDTPHGYSVVHVPAGPARVLPKDELLQYMYGFAQFLRQQWCSDGPDVAHAHFWMSGV
CCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ATQRAARAHSIPTVQTFHALGLTKRLHQGSEDTSPDCRIDVEARVAREADWVAATSTDEV
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHCCCCCEEECCHHHH
FELVRMGRARSRTSVVPCGVDLDAFTPDGPVAARGARPRIVTVGRLVPRKGFDTIVRALP
HHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHC
RIPDAELVIVGGPPAAELAGDEQARRLQRLTGELGVADRVRLLGGVTRAQMPALLRSADV
CCCCCCEEEECCCCHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCE
VACTPWYEPFGIVPLEAMACGVPVVATAVGGIRDTVVDGATGRLVPPKDPDALGEAVAAL
EEECCCCCCCCCCCHHHHHCCCHHHHHHHCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
LRDGRRGRTLGEAGRERARARYSWDRVAADTERIYERLSPARRGVGTPSTRSG
HHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA