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The map label for this gene is nuoG

Identifier: 41409305

GI number: 41409305

Start: 3556408

End: 3558744

Strand: Direct

Name: nuoG

Synonym: MAP3207

Alternate gene names: 41409305

Gene position: 3556408-3558744 (Clockwise)

Preceding gene: 41409304

Following gene: 41409306

Centisome position: 73.63

GC content: 72.06

Gene sequence:

>2337_bases
GTGACCCAAACTGCGGACACCGAAGGCCGCGTGACCCAGCCGGAGATGGTGACGCTGAGCATCGACGGCAACGAGATCAG
CGTCCCCAAGGGGACTCTGGTGATCCGCGCGGCCGAGTTGATGGGCATCCAGATCCCCCGGTTCTGCGACCACCCGCTGC
TGGAGCCGGTCGGGGCGTGCCGGCAGTGCCTGGTCGAGGTCGAGGGGCAGCGCAAGCCGATGGCCTCGTGCACCACGGTC
GCGACCGACGACATGGTGGTGCGCACCCAGCTCACCTCCGAGGCCGCCGACAAGGCCCAGCACGGCGTGATGGAGCTGCT
GCTGATCAACCATCCGCTGGACTGCCCGATGTGCGACAAGGGCGGCGAATGCCCGCTGCAGAACCAGGCAATGTCCAACG
GCCGCAGCGATTCTCGCTTCACCGACGTCAAGCGCACCTTCGCCAAGCCGATCAACATCTCCGCGCAGGTGCTGCTGGAC
CGGGAGCGCTGCATCCTGTGCGCCCGCTGCACCCGGTTCTCCGAGCAGATCGCCGGCGACCCGTTCATCGACATGCAGGA
GCGCGGCGCGCTGCAGCAGGTCGGCATCTACGCCAACGAACCGTTCGACTCCTACTTCTCGGGCAACACCGTGCAGATCT
GCCCGGTGGGGGCGCTCACCGGCACCGCCTACCGGTTCCGGGCCCGCCCCTTCGACCTGGTGTCCAGCCCCAGCGTCTGC
GAGCACTGCGCGTCCGGGTGCGCCCAGCGCACCGACCACCGCCGCGGCAAGGTGCTGCGCCGACTGGCCGGCGACGACCC
GGAGGTCAACGAGGAGTGGAACTGCGACAAGGGCCGGTGGGCGTTCAGCTACGCCACCCAGCCCGACGTGATCACCACTC
CCCTGGTCCGCGACGCCGACGGTTCGCTGCAACCGGCCTCCTGGTCGCACGCGATCGCCGCCGCGACCCGGGGGCTGGAA
TCCGCGCTGGGCAACACCGGGGTGCTGGTCGGCGGTCGGGCCACCTGGGAGGACGCCTACGCGTACTCGAAATTCGCCCG
AATCGTGTTGGGCAGCAACGACATCGACTTTCGGGCCCGGCCGAGCTCGGCCGAGGAGACCGACTTTCTGGCCGCCCGGA
TCGCCGGCCGGCCGATCACCGTCAGCTACTCCGACCTGGAGTCCGCACCGGTGGTGCTGCTGGCCGGGTTCGAGCCCGAA
GACGAGTCGCCGATCGTGTTCCTGCGGCTGCGCAAGGCGGCCCGCAAGCACGGGGTGCCGGTGTACGCGGTGGCGCCGTT
CGCCACCCGCTCGCTGACCAAGATGTCGGGTCGGCTGATCAAAACCGCGCCCGGCGCCGAGGCCTCGGCGTTGGACCGGC
TGGCCACCGGCGAAGTGGGCGACCTGCTGTCCACCCCGGGCGCGGTCATCATGGTCGGCGAACGGCTGGCCACGGCGCCG
GGCGGACTGTCCGCCGCCGCCCGGCTGGCCGACACCACCGGCGCCCGGCTGGTCTGGGTTCCGCGGCGCGCCGGCGATCG
CGGCGCCCTGGAGGCCGGGGCGCTGCCCGGGCTGCTGCCCGGCGGCCGGCCCGTCGCTGACGACGACGCCCGCGCGCAGA
TCGCGTCGGCCTGGAACGTGTCCGAATTGCCTTGCGGCCCTGGGCGTGACGTGCAGGAGATGCTGGCCGCCGCCGCCGCC
GGCACGCTGGGCGCACTGCTGGTCGGCGGTGTGGACCCGGACGACTTCGCCGATCCGCAGGCGGTGCTGGCGGCGCTGGA
CGGGGTGGGCTTCGTGGTCAGCCTGGAGCTGCGGCACAGCGCCGTCACGCAGCGCGCCGACGTGGTGTTCCCGGTCGCGC
CGACCACCCAGAAGGCGGGTGCCTTCGTCAACTGGGAGGGCCGGTTCCGCCCGTTCCAGGCCGCGCTGCGCGGCAGCATG
ACGCAGGCCGGCCAATCCGATCACCAGGTGCTCGACACTTTGGCCGACGAGCTGGGCGTCTACCTGGGGACGGCGACCGT
CGAGGAGATCCGCACCGAATACGCCGCGCTGCCCTACTGGGAGGGCAAACGCGCGGCCGGCCCGGACGTCGCGGCCGCCG
AGCCGGCGCCGCCCGGGGCGGGTGAAGCGGTGCTGACCGGTTGGCGGATGCTGCTGGACAACGGTCGCATGCAAGACGGC
GAACCGCATCTGGCCGGCACGGCGCGCCAGCCCGTGCTGCGGCTGTCGGCCGACACCGCCGCCGAGATCGGCGCCGCCGA
CGGCGATGCGGTCACCGTGAGCACGCCGCGCGGATCGATCAGCCTGCCGCTGGTGATCACCGACATGCCCGACCCGGGTG
GGTGTGGCTGCCGCTGA

Upstream 100 bases:

>100_bases
CGATCAAGTACTTCCGCGACGAGTACGTCGCCCACGTCGAGAACGGCAGATGCCCGTTCGACCCGCGAGACTCCATGCTG
ACACCGAACGGGAGCGACTC

Downstream 100 bases:

>100_bases
ACTCCTCCGGCTCGGCGGTGCACCGCCAGCTCGGCGTCACCGTCGGCGCCACGGTGCGGATTGGAGTTGGCTCGTGACGA
CCCCCACTGACCGCCTTCGG

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 778; Mature: 777

Protein sequence:

>778_residues
MTQTADTEGRVTQPEMVTLSIDGNEISVPKGTLVIRAAELMGIQIPRFCDHPLLEPVGACRQCLVEVEGQRKPMASCTTV
ATDDMVVRTQLTSEAADKAQHGVMELLLINHPLDCPMCDKGGECPLQNQAMSNGRSDSRFTDVKRTFAKPINISAQVLLD
RERCILCARCTRFSEQIAGDPFIDMQERGALQQVGIYANEPFDSYFSGNTVQICPVGALTGTAYRFRARPFDLVSSPSVC
EHCASGCAQRTDHRRGKVLRRLAGDDPEVNEEWNCDKGRWAFSYATQPDVITTPLVRDADGSLQPASWSHAIAAATRGLE
SALGNTGVLVGGRATWEDAYAYSKFARIVLGSNDIDFRARPSSAEETDFLAARIAGRPITVSYSDLESAPVVLLAGFEPE
DESPIVFLRLRKAARKHGVPVYAVAPFATRSLTKMSGRLIKTAPGAEASALDRLATGEVGDLLSTPGAVIMVGERLATAP
GGLSAAARLADTTGARLVWVPRRAGDRGALEAGALPGLLPGGRPVADDDARAQIASAWNVSELPCGPGRDVQEMLAAAAA
GTLGALLVGGVDPDDFADPQAVLAALDGVGFVVSLELRHSAVTQRADVVFPVAPTTQKAGAFVNWEGRFRPFQAALRGSM
TQAGQSDHQVLDTLADELGVYLGTATVEEIRTEYAALPYWEGKRAAGPDVAAAEPAPPGAGEAVLTGWRMLLDNGRMQDG
EPHLAGTARQPVLRLSADTAAEIGAADGDAVTVSTPRGSISLPLVITDMPDPGGCGCR

Sequences:

>Translated_778_residues
MTQTADTEGRVTQPEMVTLSIDGNEISVPKGTLVIRAAELMGIQIPRFCDHPLLEPVGACRQCLVEVEGQRKPMASCTTV
ATDDMVVRTQLTSEAADKAQHGVMELLLINHPLDCPMCDKGGECPLQNQAMSNGRSDSRFTDVKRTFAKPINISAQVLLD
RERCILCARCTRFSEQIAGDPFIDMQERGALQQVGIYANEPFDSYFSGNTVQICPVGALTGTAYRFRARPFDLVSSPSVC
EHCASGCAQRTDHRRGKVLRRLAGDDPEVNEEWNCDKGRWAFSYATQPDVITTPLVRDADGSLQPASWSHAIAAATRGLE
SALGNTGVLVGGRATWEDAYAYSKFARIVLGSNDIDFRARPSSAEETDFLAARIAGRPITVSYSDLESAPVVLLAGFEPE
DESPIVFLRLRKAARKHGVPVYAVAPFATRSLTKMSGRLIKTAPGAEASALDRLATGEVGDLLSTPGAVIMVGERLATAP
GGLSAAARLADTTGARLVWVPRRAGDRGALEAGALPGLLPGGRPVADDDARAQIASAWNVSELPCGPGRDVQEMLAAAAA
GTLGALLVGGVDPDDFADPQAVLAALDGVGFVVSLELRHSAVTQRADVVFPVAPTTQKAGAFVNWEGRFRPFQAALRGSM
TQAGQSDHQVLDTLADELGVYLGTATVEEIRTEYAALPYWEGKRAAGPDVAAAEPAPPGAGEAVLTGWRMLLDNGRMQDG
EPHLAGTARQPVLRLSADTAAEIGAADGDAVTVSTPRGSISLPLVITDMPDPGGCGCR
>Mature_777_residues
TQTADTEGRVTQPEMVTLSIDGNEISVPKGTLVIRAAELMGIQIPRFCDHPLLEPVGACRQCLVEVEGQRKPMASCTTVA
TDDMVVRTQLTSEAADKAQHGVMELLLINHPLDCPMCDKGGECPLQNQAMSNGRSDSRFTDVKRTFAKPINISAQVLLDR
ERCILCARCTRFSEQIAGDPFIDMQERGALQQVGIYANEPFDSYFSGNTVQICPVGALTGTAYRFRARPFDLVSSPSVCE
HCASGCAQRTDHRRGKVLRRLAGDDPEVNEEWNCDKGRWAFSYATQPDVITTPLVRDADGSLQPASWSHAIAAATRGLES
ALGNTGVLVGGRATWEDAYAYSKFARIVLGSNDIDFRARPSSAEETDFLAARIAGRPITVSYSDLESAPVVLLAGFEPED
ESPIVFLRLRKAARKHGVPVYAVAPFATRSLTKMSGRLIKTAPGAEASALDRLATGEVGDLLSTPGAVIMVGERLATAPG
GLSAAARLADTTGARLVWVPRRAGDRGALEAGALPGLLPGGRPVADDDARAQIASAWNVSELPCGPGRDVQEMLAAAAAG
TLGALLVGGVDPDDFADPQAVLAALDGVGFVVSLELRHSAVTQRADVVFPVAPTTQKAGAFVNWEGRFRPFQAALRGSMT
QAGQSDHQVLDTLADELGVYLGTATVEEIRTEYAALPYWEGKRAAGPDVAAAEPAPPGAGEAVLTGWRMLLDNGRMQDGE
PHLAGTARQPVLRLSADTAAEIGAADGDAVTVSTPRGSISLPLVITDMPDPGGCGCR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be menaquinone. Couples the redox reaction to proton transloca

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=400, Percent_Identity=37.25, Blast_Score=245, Evalue=1e-64,
Organism=Escherichia coli, GI145693161, Length=649, Percent_Identity=27.1186440677966, Blast_Score=171, Evalue=2e-43,
Organism=Escherichia coli, GI3868721, Length=536, Percent_Identity=23.3208955223881, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1788534, Length=230, Percent_Identity=25.6521739130435, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565758, Length=682, Percent_Identity=32.5513196480938, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI32566231, Length=639, Percent_Identity=33.489827856025, Blast_Score=266, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI193209088, Length=262, Percent_Identity=43.5114503816794, Blast_Score=199, Evalue=5e-51,
Organism=Drosophila melanogaster, GI24640559, Length=672, Percent_Identity=31.8452380952381, Blast_Score=255, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24640557, Length=672, Percent_Identity=31.8452380952381, Blast_Score=255, Evalue=1e-67,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574 [H]

Pfam domain/function: PF00111 Fer2; PF00384 Molybdopterin; PF01568 Molydop_binding; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 82390; Mature: 82259

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTADTEGRVTQPEMVTLSIDGNEISVPKGTLVIRAAELMGIQIPRFCDHPLLEPVGAC
CCCCCCCCCCCCCCEEEEEEECCCEEECCCCEEEEEEHHHHCCCCCHHCCCHHHHHHHHH
RQCLVEVEGQRKPMASCTTVATDDMVVRTQLTSEAADKAQHGVMELLLINHPLDCPMCDK
HHHHHHHCCCCCCCCHHEEECCCCEEEEEHHHHHHHHHHHHHHHHHHEECCCCCCCCCCC
GGECPLQNQAMSNGRSDSRFTDVKRTFAKPINISAQVLLDRERCILCARCTRFSEQIAGD
CCCCCCCHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCC
PFIDMQERGALQQVGIYANEPFDSYFSGNTVQICPVGALTGTAYRFRARPFDLVSSPSVC
CCCCHHHCCCHHHCCEEECCCCHHHCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCHHH
EHCASGCAQRTDHRRGKVLRRLAGDDPEVNEEWNCDKGRWAFSYATQPDVITTPLVRDAD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCEECCCEECCC
GSLQPASWSHAIAAATRGLESALGNTGVLVGGRATWEDAYAYSKFARIVLGSNDIDFRAR
CCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHEEEECCCCCCEEEC
PSSAEETDFLAARIAGRPITVSYSDLESAPVVLLAGFEPEDESPIVFLRLRKAARKHGVP
CCCCCHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCCCCCCCEEEEEEHHHHHHCCCC
VYAVAPFATRSLTKMSGRLIKTAPGAEASALDRLATGEVGDLLSTPGAVIMVGERLATAP
EEEECCHHHHHHHHHCCEEEEECCCCCHHHHHHHHCCCHHHHHCCCCEEEEECCHHCCCC
GGLSAAARLADTTGARLVWVPRRAGDRGALEAGALPGLLPGGRPVADDDARAQIASAWNV
CCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCC
SELPCGPGRDVQEMLAAAAAGTLGALLVGGVDPDDFADPQAVLAALDGVGFVVSLELRHS
CCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHCCCCEEEEEEEHHH
AVTQRADVVFPVAPTTQKAGAFVNWEGRFRPFQAALRGSMTQAGQSDHQVLDTLADELGV
HHHCCCCEEEECCCCCHHCCEEEEECCCCCHHHHHHHCCHHHCCCHHHHHHHHHHHHHHH
YLGTATVEEIRTEYAALPYWEGKRAAGPDVAAAEPAPPGAGEAVLTGWRMLLDNGRMQDG
EECHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
EPHLAGTARQPVLRLSADTAAEIGAADGDAVTVSTPRGSISLPLVITDMPDPGGCGCR
CCCCCCCCCCCEEEECCCCHHHCCCCCCCEEEEECCCCCEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
TQTADTEGRVTQPEMVTLSIDGNEISVPKGTLVIRAAELMGIQIPRFCDHPLLEPVGAC
CCCCCCCCCCCCCEEEEEEECCCEEECCCCEEEEEEHHHHCCCCCHHCCCHHHHHHHHH
RQCLVEVEGQRKPMASCTTVATDDMVVRTQLTSEAADKAQHGVMELLLINHPLDCPMCDK
HHHHHHHCCCCCCCCHHEEECCCCEEEEEHHHHHHHHHHHHHHHHHHEECCCCCCCCCCC
GGECPLQNQAMSNGRSDSRFTDVKRTFAKPINISAQVLLDRERCILCARCTRFSEQIAGD
CCCCCCCHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCC
PFIDMQERGALQQVGIYANEPFDSYFSGNTVQICPVGALTGTAYRFRARPFDLVSSPSVC
CCCCHHHCCCHHHCCEEECCCCHHHCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCHHH
EHCASGCAQRTDHRRGKVLRRLAGDDPEVNEEWNCDKGRWAFSYATQPDVITTPLVRDAD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCEECCCEECCC
GSLQPASWSHAIAAATRGLESALGNTGVLVGGRATWEDAYAYSKFARIVLGSNDIDFRAR
CCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHEEEECCCCCCEEEC
PSSAEETDFLAARIAGRPITVSYSDLESAPVVLLAGFEPEDESPIVFLRLRKAARKHGVP
CCCCCHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCCCCCCCEEEEEEHHHHHHCCCC
VYAVAPFATRSLTKMSGRLIKTAPGAEASALDRLATGEVGDLLSTPGAVIMVGERLATAP
EEEECCHHHHHHHHHCCEEEEECCCCCHHHHHHHHCCCHHHHHCCCCEEEEECCHHCCCC
GGLSAAARLADTTGARLVWVPRRAGDRGALEAGALPGLLPGGRPVADDDARAQIASAWNV
CCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCC
SELPCGPGRDVQEMLAAAAAGTLGALLVGGVDPDDFADPQAVLAALDGVGFVVSLELRHS
CCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHCCCCEEEEEEEHHH
AVTQRADVVFPVAPTTQKAGAFVNWEGRFRPFQAALRGSMTQAGQSDHQVLDTLADELGV
HHHCCCCEEEECCCCCHHCCEEEEECCCCCHHHHHHHCCHHHCCCHHHHHHHHHHHHHHH
YLGTATVEEIRTEYAALPYWEGKRAAGPDVAAAEPAPPGAGEAVLTGWRMLLDNGRMQDG
EECHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
EPHLAGTARQPVLRLSADTAAEIGAADGDAVTVSTPRGSISLPLVITDMPDPGGCGCR
CCCCCCCCCCCEEEECCCCHHHCCCCCCCEEEEECCCCCEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]