BacMap

Definition	Mycobacterium avium subsp. paratuberculosis K-10, complete genome.
Accession	NC_002944
Length	4,829,781

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The map label for this gene is feaB [C]

Identifier: 41409241

GI number: 41409241

Start: 3497408

End: 3497935

Strand: Direct

Name: feaB [C]

Synonym: MAP3143

Alternate gene names: 41409241

Gene position: 3497408-3497935 (Clockwise)

Preceding gene: 41409240

Following gene: 41409245

Centisome position: 72.41

GC content: 71.59

Gene sequence:

>528_bases
ATGAGCGGCCTGCGGGTCGGCGACCCCGCCGACCCGGACACCGACCTCGGCCCGCTGGTGTCGCGCCGCCAGCAGCAGCG
GGTCCGCGACTACATCCGGATCGGCCAGCAGGAGGGGGCGCGGTTGGTGGTCGGCGGTGCGGATATGCCCGACGGGCTCG
ACCGCGGCTGGTATGTCCGGCCCACCCTGTTCGCCGCCGCCGGCAACGCCATGCGCATCGCACGCGAAGAGATCTTCGGT
CCGGTCATCACCGTCATCCCATACCGCGACGACGACGAGGCGGTGGCGATCGCCAACGACTCCGATTACGGCCTGGCCGG
GTCGGTGTGGAGTGACGACACCGACCGCGCGCTGGCGCTGGCCACCCGGATTCACACCGGCACCGTCGGCGTCAACCAGG
GCTACACCATGGACCCGTTCGCGCCGTTCGGCGGTGTCAAGGCCAGCGGCTACGGCCGCGAGCTGGGGCCCGAGGGGCTC
GACGGCTACCTCGACACGAAATCGATCGCGGTCGCGGCGAGCGGCTAG

Upstream 100 bases:

>100_bases
CGGCCAGCCTGTCCAACAGCGGCCAGATCTGCATGCGCTGACCCGGGTGCTGGTTCCCCAAGCGCGCCATGACGATTGCG
TCGACGCGCTCGCCGCCCAG

Downstream 100 bases:

>100_bases
CGAGCCTCGCTCACCACGTGGACGGCGACGTAACCGATCGGGATGCCGGTCCAGGTGGCGATGCACTCCCGGGCGGCCAC
CTCGACCGTGGCCCGGCTGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MSGLRVGDPADPDTDLGPLVSRRQQQRVRDYIRIGQQEGARLVVGGADMPDGLDRGWYVRPTLFAAAGNAMRIAREEIFG
PVITVIPYRDDDEAVAIANDSDYGLAGSVWSDDTDRALALATRIHTGTVGVNQGYTMDPFAPFGGVKASGYGRELGPEGL
DGYLDTKSIAVAASG

Sequences:

>Translated_175_residues
MSGLRVGDPADPDTDLGPLVSRRQQQRVRDYIRIGQQEGARLVVGGADMPDGLDRGWYVRPTLFAAAGNAMRIAREEIFG
PVITVIPYRDDDEAVAIANDSDYGLAGSVWSDDTDRALALATRIHTGTVGVNQGYTMDPFAPFGGVKASGYGRELGPEGL
DGYLDTKSIAVAASG
>Mature_174_residues
SGLRVGDPADPDTDLGPLVSRRQQQRVRDYIRIGQQEGARLVVGGADMPDGLDRGWYVRPTLFAAAGNAMRIAREEIFGP
VITVIPYRDDDEAVAIANDSDYGLAGSVWSDDTDRALALATRIHTGTVGVNQGYTMDPFAPFGGVKASGYGRELGPEGLD
GYLDTKSIAVAASG

Specific function: Acts Almost Equally Well On Phenylacetaldehyde, 4- Hydroxyphenylacetaldehyde And 3,4-Dihydroxyphenylacetaldehyde. [C]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777730, Length=167, Percent_Identity=41.9161676646707, Blast_Score=144, Evalue=3e-35,
Organism=Homo sapiens, GI153266822, Length=166, Percent_Identity=40.3614457831325, Blast_Score=142, Evalue=2e-34,
Organism=Homo sapiens, GI25777732, Length=166, Percent_Identity=42.7710843373494, Blast_Score=139, Evalue=1e-33,
Organism=Homo sapiens, GI25777726, Length=167, Percent_Identity=40.1197604790419, Blast_Score=137, Evalue=3e-33,
Organism=Homo sapiens, GI25777724, Length=167, Percent_Identity=40.1197604790419, Blast_Score=137, Evalue=3e-33,
Organism=Homo sapiens, GI25777728, Length=167, Percent_Identity=40.1197604790419, Blast_Score=137, Evalue=4e-33,
Organism=Homo sapiens, GI21361176, Length=169, Percent_Identity=38.4615384615385, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI238814322, Length=170, Percent_Identity=36.4705882352941, Blast_Score=121, Evalue=4e-28,
Organism=Homo sapiens, GI115387104, Length=172, Percent_Identity=34.3023255813954, Blast_Score=120, Evalue=5e-28,
Organism=Homo sapiens, GI21614513, Length=168, Percent_Identity=38.0952380952381, Blast_Score=117, Evalue=6e-27,
Organism=Homo sapiens, GI301500698, Length=171, Percent_Identity=34.5029239766082, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI12007648, Length=171, Percent_Identity=34.5029239766082, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI25952152, Length=150, Percent_Identity=34, Blast_Score=96, Evalue=1e-20,
Organism=Homo sapiens, GI25777721, Length=167, Percent_Identity=37.125748502994, Blast_Score=95, Evalue=3e-20,
Organism=Homo sapiens, GI4507229, Length=167, Percent_Identity=37.125748502994, Blast_Score=95, Evalue=3e-20,
Organism=Homo sapiens, GI11095441, Length=170, Percent_Identity=32.3529411764706, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI223972653, Length=137, Percent_Identity=36.4963503649635, Blast_Score=77, Evalue=5e-15,
Organism=Homo sapiens, GI223972651, Length=137, Percent_Identity=36.4963503649635, Blast_Score=77, Evalue=6e-15,
Organism=Homo sapiens, GI73695881, Length=171, Percent_Identity=29.2397660818713, Blast_Score=77, Evalue=7e-15,
Organism=Homo sapiens, GI73695879, Length=171, Percent_Identity=29.2397660818713, Blast_Score=77, Evalue=7e-15,
Organism=Homo sapiens, GI188035924, Length=175, Percent_Identity=29.7142857142857, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI310128089, Length=165, Percent_Identity=30.9090909090909, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI310128103, Length=165, Percent_Identity=30.9090909090909, Blast_Score=74, Evalue=5e-14,
Organism=Homo sapiens, GI310128095, Length=164, Percent_Identity=31.0975609756098, Blast_Score=74, Evalue=6e-14,
Organism=Homo sapiens, GI310128091, Length=164, Percent_Identity=31.0975609756098, Blast_Score=74, Evalue=7e-14,
Organism=Homo sapiens, GI310128097, Length=164, Percent_Identity=31.0975609756098, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI310128093, Length=164, Percent_Identity=31.0975609756098, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI71773324, Length=171, Percent_Identity=28.6549707602339, Blast_Score=70, Evalue=7e-13,
Organism=Homo sapiens, GI4502043, Length=171, Percent_Identity=28.6549707602339, Blast_Score=70, Evalue=7e-13,
Organism=Homo sapiens, GI238814371, Length=171, Percent_Identity=28.6549707602339, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI87081896, Length=171, Percent_Identity=40.3508771929825, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786504, Length=169, Percent_Identity=42.0118343195266, Blast_Score=129, Evalue=7e-32,
Organism=Escherichia coli, GI87082295, Length=176, Percent_Identity=38.0681818181818, Blast_Score=118, Evalue=2e-28,
Organism=Escherichia coli, GI1787715, Length=171, Percent_Identity=36.2573099415205, Blast_Score=114, Evalue=2e-27,
Organism=Escherichia coli, GI1789015, Length=171, Percent_Identity=32.7485380116959, Blast_Score=113, Evalue=8e-27,
Organism=Escherichia coli, GI87081926, Length=168, Percent_Identity=33.9285714285714, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1787558, Length=168, Percent_Identity=35.1190476190476, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787684, Length=170, Percent_Identity=31.1764705882353, Blast_Score=88, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562198, Length=166, Percent_Identity=43.9759036144578, Blast_Score=144, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI32564736, Length=166, Percent_Identity=44.578313253012, Blast_Score=140, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI25144435, Length=166, Percent_Identity=44.578313253012, Blast_Score=140, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI25143876, Length=169, Percent_Identity=37.8698224852071, Blast_Score=126, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI25143874, Length=169, Percent_Identity=37.8698224852071, Blast_Score=125, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17551164, Length=169, Percent_Identity=34.9112426035503, Blast_Score=122, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71995606, Length=169, Percent_Identity=36.6863905325444, Blast_Score=115, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI133930964, Length=169, Percent_Identity=36.094674556213, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17534119, Length=162, Percent_Identity=35.8024691358025, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71986308, Length=172, Percent_Identity=30.2325581395349, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71995613, Length=109, Percent_Identity=36.697247706422, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32564151, Length=136, Percent_Identity=32.3529411764706, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320917, Length=169, Percent_Identity=41.4201183431953, Blast_Score=144, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6324950, Length=166, Percent_Identity=39.7590361445783, Blast_Score=139, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6325196, Length=168, Percent_Identity=38.0952380952381, Blast_Score=135, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6323822, Length=167, Percent_Identity=37.7245508982036, Blast_Score=129, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6323821, Length=167, Percent_Identity=38.3233532934132, Blast_Score=129, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6321828, Length=170, Percent_Identity=32.9411764705882, Blast_Score=97, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319478, Length=166, Percent_Identity=29.5180722891566, Blast_Score=91, Evalue=1e-19,
Organism=Drosophila melanogaster, GI20129399, Length=169, Percent_Identity=43.1952662721894, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24650465, Length=167, Percent_Identity=40.1197604790419, Blast_Score=130, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24585660, Length=170, Percent_Identity=40.5882352941176, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281362580, Length=171, Percent_Identity=36.2573099415205, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI62472918, Length=171, Percent_Identity=36.2573099415205, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI62472926, Length=171, Percent_Identity=36.2573099415205, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI62472936, Length=171, Percent_Identity=36.2573099415205, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI21356737, Length=171, Percent_Identity=36.2573099415205, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24638876, Length=170, Percent_Identity=32.3529411764706, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24638878, Length=170, Percent_Identity=32.3529411764706, Blast_Score=88, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.3 [H]

Molecular weight: Translated: 18588; Mature: 18457

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGLRVGDPADPDTDLGPLVSRRQQQRVRDYIRIGQQEGARLVVGGADMPDGLDRGWYVR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCEEEC
PTLFAAAGNAMRIAREEIFGPVITVIPYRDDDEAVAIANDSDYGLAGSVWSDDTDRALAL
CCCEECCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEH
ATRIHTGTVGVNQGYTMDPFAPFGGVKASGYGRELGPEGLDGYLDTKSIAVAASG
HHHHCCCEEECCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure 
SGLRVGDPADPDTDLGPLVSRRQQQRVRDYIRIGQQEGARLVVGGADMPDGLDRGWYVR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCEEEC
PTLFAAAGNAMRIAREEIFGPVITVIPYRDDDEAVAIANDSDYGLAGSVWSDDTDRALAL
CCCEECCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEH
ATRIHTGTVGVNQGYTMDPFAPFGGVKASGYGRELGPEGLDGYLDTKSIAVAASG
HHHHCCCEEECCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA