BacMap

Definition	Mycobacterium avium subsp. paratuberculosis K-10, complete genome.
Accession	NC_002944
Length	4,829,781

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The map label for this gene is dhaS [H]

Identifier: 41409240

GI number: 41409240

Start: 3496470

End: 3497348

Strand: Direct

Name: dhaS [H]

Synonym: MAP3142

Alternate gene names: 41409240

Gene position: 3496470-3497348 (Clockwise)

Preceding gene: 41409230

Following gene: 41409241

Centisome position: 72.39

GC content: 72.47

Gene sequence:

>879_bases
TTGATATTGGCCCGGGAGGCGCGGATGGGCCACGACGCCGGAGTGCGAACCGACGGACAGGGCCGGCGCGCCGACGTCAT
CCGCGTCATCTCGCCACACACCGAGCAGCCCGTCGCCGAGGTCGATGCGGCGACACCCTCCGACGTCGACGCGGCGGTGG
CCGCGGCGCGAGCGGCGTTCGACGCCGGACCGTGGAGCCGCGGCGGGCCGTCACACCGCATCGCCGCGATCCGCCGGCTG
GCCGACATCTACGACCGGCGCCGCGCCGAGATGGCCGACACCATCACCGCCGAGATCGGCGCCCCGATCAGCTTCGCCCG
GCGTGCCCAGGTGGGCCTGCCCGCCTTCATGATCCGCGCGTTCTGCGACCTGGCCGAGCGCCATCCCTGGCAGGAGACCA
GGCCCGGGTTCTTCGGGAGCGACGTCTACGTGCGCAGGGAACCCGTCGGGGTCGTCGCGGCGATCGTGCCGTGGAACATG
CCGCAGTTCCTCATCGTCACCAAACTCATCCCGGCCCTGCTGGCCGGCTGCACCGTCGTGCTCAAGCCGGCACCCGAAAG
TCCTTTGGACGCACTGCTTTTAGCCGAGATGATCTCCGAGGCCGACCTGCCGCCCGGCGCGGTCAGCGTGCTGCCCGGCG
ACGCCGCGCTGGGCGCCTACCTCGCCGGGCACCGCGGGGTGGACAAGGTGTCCTTCACCGGCTCGACGGCTGCCGGGCGC
GCCGTCGCCGCGGCCTGCGCGGCCAACCTCACCAAGGTCAGTCTGGAACTGGGCGGCAAGTCCGCCGCACTGGTGCTCGA
CGATGCGCCGCCGGACAAGGTGGCCGCCGGGGTGCGCGCGGCCAGCCTGTCCAACAGCGGCCAGATCTGCATGCGCTGA

Upstream 100 bases:

>100_bases
CGCCGCCCGCGCGAAACAACCAGCTGCGCACCGGTTTCACCGGTCCCGCGGAGCTCCGTCACGGGCGACGGTATATCCTC
GACCCGTCATTAGCAAGTAG

Downstream 100 bases:

>100_bases
CCCGGGTGCTGGTTCCCCAAGCGCGCCATGACGATTGCGTCGACGCGCTCGCCGCCCAGATGAGCGGCCTGCGGGTCGGC
GACCCCGCCGACCCGGACAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MILAREARMGHDAGVRTDGQGRRADVIRVISPHTEQPVAEVDAATPSDVDAAVAAARAAFDAGPWSRGGPSHRIAAIRRL
ADIYDRRRAEMADTITAEIGAPISFARRAQVGLPAFMIRAFCDLAERHPWQETRPGFFGSDVYVRREPVGVVAAIVPWNM
PQFLIVTKLIPALLAGCTVVLKPAPESPLDALLLAEMISEADLPPGAVSVLPGDAALGAYLAGHRGVDKVSFTGSTAAGR
AVAAACAANLTKVSLELGGKSAALVLDDAPPDKVAAGVRAASLSNSGQICMR

Sequences:

>Translated_292_residues
MILAREARMGHDAGVRTDGQGRRADVIRVISPHTEQPVAEVDAATPSDVDAAVAAARAAFDAGPWSRGGPSHRIAAIRRL
ADIYDRRRAEMADTITAEIGAPISFARRAQVGLPAFMIRAFCDLAERHPWQETRPGFFGSDVYVRREPVGVVAAIVPWNM
PQFLIVTKLIPALLAGCTVVLKPAPESPLDALLLAEMISEADLPPGAVSVLPGDAALGAYLAGHRGVDKVSFTGSTAAGR
AVAAACAANLTKVSLELGGKSAALVLDDAPPDKVAAGVRAASLSNSGQICMR
>Mature_292_residues
MILAREARMGHDAGVRTDGQGRRADVIRVISPHTEQPVAEVDAATPSDVDAAVAAARAAFDAGPWSRGGPSHRIAAIRRL
ADIYDRRRAEMADTITAEIGAPISFARRAQVGLPAFMIRAFCDLAERHPWQETRPGFFGSDVYVRREPVGVVAAIVPWNM
PQFLIVTKLIPALLAGCTVVLKPAPESPLDALLLAEMISEADLPPGAVSVLPGDAALGAYLAGHRGVDKVSFTGSTAAGR
AVAAACAANLTKVSLELGGKSAALVLDDAPPDKVAAGVRAASLSNSGQICMR

Specific function: Acts Almost Equally Well On Phenylacetaldehyde, 4- Hydroxyphenylacetaldehyde And 3,4-Dihydroxyphenylacetaldehyde. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777732, Length=267, Percent_Identity=40.8239700374532, Blast_Score=177, Evalue=9e-45,
Organism=Homo sapiens, GI153266822, Length=263, Percent_Identity=38.7832699619772, Blast_Score=167, Evalue=8e-42,
Organism=Homo sapiens, GI25777724, Length=276, Percent_Identity=38.4057971014493, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI21361176, Length=269, Percent_Identity=38.2899628252788, Blast_Score=164, Evalue=7e-41,
Organism=Homo sapiens, GI25777730, Length=266, Percent_Identity=39.8496240601504, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI21614513, Length=297, Percent_Identity=36.3636363636364, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI238814322, Length=269, Percent_Identity=36.0594795539033, Blast_Score=144, Evalue=8e-35,
Organism=Homo sapiens, GI12007648, Length=269, Percent_Identity=31.2267657992565, Blast_Score=141, Evalue=5e-34,
Organism=Homo sapiens, GI25777728, Length=230, Percent_Identity=37.3913043478261, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI115387104, Length=264, Percent_Identity=34.8484848484849, Blast_Score=138, Evalue=5e-33,
Organism=Homo sapiens, GI25952152, Length=263, Percent_Identity=30.7984790874525, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI4507229, Length=238, Percent_Identity=34.0336134453782, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI25777721, Length=251, Percent_Identity=32.2709163346614, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI25777726, Length=274, Percent_Identity=32.4817518248175, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI206597441, Length=253, Percent_Identity=32.0158102766798, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI206597439, Length=253, Percent_Identity=32.0158102766798, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI22907049, Length=253, Percent_Identity=32.0158102766798, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI11095441, Length=266, Percent_Identity=25.9398496240602, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4502043, Length=149, Percent_Identity=40.2684563758389, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI238814371, Length=149, Percent_Identity=40.2684563758389, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI71773324, Length=149, Percent_Identity=40.2684563758389, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI73695881, Length=150, Percent_Identity=38, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI73695879, Length=150, Percent_Identity=38, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI73466520, Length=151, Percent_Identity=35.0993377483444, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI4557303, Length=151, Percent_Identity=35.0993377483444, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI310128093, Length=294, Percent_Identity=25.5102040816327, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI310128103, Length=294, Percent_Identity=25.1700680272109, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI310128087, Length=294, Percent_Identity=25.1700680272109, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI188035924, Length=298, Percent_Identity=24.496644295302, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI223972651, Length=141, Percent_Identity=37.5886524822695, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI310128091, Length=290, Percent_Identity=25.1724137931034, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI87081896, Length=268, Percent_Identity=39.5522388059701, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI1787558, Length=270, Percent_Identity=37.4074074074074, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1789015, Length=272, Percent_Identity=36.0294117647059, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786504, Length=272, Percent_Identity=38.9705882352941, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI1787684, Length=268, Percent_Identity=33.5820895522388, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI87082295, Length=275, Percent_Identity=34.1818181818182, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787715, Length=227, Percent_Identity=34.8017621145374, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI87081926, Length=264, Percent_Identity=30.3030303030303, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1788042, Length=269, Percent_Identity=25.6505576208178, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787250, Length=270, Percent_Identity=30.3703703703704, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562198, Length=274, Percent_Identity=36.8613138686131, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI133930964, Length=271, Percent_Identity=37.2693726937269, Blast_Score=162, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI25144435, Length=272, Percent_Identity=36.7647058823529, Blast_Score=158, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI25143874, Length=269, Percent_Identity=36.8029739776952, Blast_Score=144, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI25143876, Length=269, Percent_Identity=36.8029739776952, Blast_Score=144, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI32564736, Length=222, Percent_Identity=38.2882882882883, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17551164, Length=276, Percent_Identity=31.1594202898551, Blast_Score=130, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17534119, Length=269, Percent_Identity=33.457249070632, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71995606, Length=272, Percent_Identity=35.2941176470588, Blast_Score=127, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI71995613, Length=272, Percent_Identity=35.2941176470588, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71986308, Length=288, Percent_Identity=28.125, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI115534176, Length=291, Percent_Identity=26.8041237113402, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17564084, Length=249, Percent_Identity=27.3092369477912, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25146394, Length=148, Percent_Identity=34.4594594594595, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32566756, Length=148, Percent_Identity=34.4594594594595, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25146391, Length=148, Percent_Identity=34.4594594594595, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71990744, Length=148, Percent_Identity=33.1081081081081, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17534447, Length=148, Percent_Identity=33.1081081081081, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115532534, Length=148, Percent_Identity=33.1081081081081, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI32564151, Length=148, Percent_Identity=33.1081081081081, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323821, Length=267, Percent_Identity=37.8277153558052, Blast_Score=170, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6323822, Length=267, Percent_Identity=38.9513108614232, Blast_Score=170, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6320917, Length=272, Percent_Identity=36.7647058823529, Blast_Score=165, Evalue=7e-42,
Organism=Saccharomyces cerevisiae, GI6324950, Length=273, Percent_Identity=35.1648351648352, Blast_Score=164, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6325196, Length=264, Percent_Identity=34.469696969697, Blast_Score=143, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6319478, Length=270, Percent_Identity=30.3703703703704, Blast_Score=122, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6321828, Length=287, Percent_Identity=26.4808362369338, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323757, Length=160, Percent_Identity=32.5, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI20129399, Length=276, Percent_Identity=38.768115942029, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24585660, Length=285, Percent_Identity=34.7368421052632, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24650465, Length=272, Percent_Identity=35.2941176470588, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI281362580, Length=267, Percent_Identity=29.9625468164794, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI62472918, Length=267, Percent_Identity=29.9625468164794, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI62472926, Length=267, Percent_Identity=29.9625468164794, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI62472936, Length=267, Percent_Identity=29.9625468164794, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21356737, Length=267, Percent_Identity=29.9625468164794, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24638878, Length=273, Percent_Identity=26.7399267399267, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24638876, Length=273, Percent_Identity=26.7399267399267, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24666674, Length=280, Percent_Identity=27.1428571428571, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281360293, Length=248, Percent_Identity=27.0161290322581, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281360303, Length=248, Percent_Identity=27.0161290322581, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281360299, Length=248, Percent_Identity=27.0161290322581, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281360297, Length=248, Percent_Identity=27.0161290322581, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281360295, Length=248, Percent_Identity=27.0161290322581, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24586250, Length=248, Percent_Identity=27.0161290322581, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45552499, Length=248, Percent_Identity=27.0161290322581, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281360301, Length=248, Percent_Identity=27.0161290322581, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.3 [H]

Molecular weight: Translated: 30482; Mature: 30482

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILAREARMGHDAGVRTDGQGRRADVIRVISPHTEQPVAEVDAATPSDVDAAVAAARAAF
CEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHCCCCCCCHHHHHHHHHHHH
DAGPWSRGGPSHRIAAIRRLADIYDRRRAEMADTITAEIGAPISFARRAQVGLPAFMIRA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHH
FCDLAERHPWQETRPGFFGSDVYVRREPVGVVAAIVPWNMPQFLIVTKLIPALLAGCTVV
HHHHHHCCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHCCEEE
LKPAPESPLDALLLAEMISEADLPPGAVSVLPGDAALGAYLAGHRGVDKVSFTGSTAAGR
EECCCCCHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHCCCCCCEEEECCCCHHHH
AVAAACAANLTKVSLELGGKSAALVLDDAPPDKVAAGVRAASLSNSGQICMR
HHHHHHHHHHHEEEEEECCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEC
>Mature Secondary Structure
MILAREARMGHDAGVRTDGQGRRADVIRVISPHTEQPVAEVDAATPSDVDAAVAAARAAF
CEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHCCCCCCCHHHHHHHHHHHH
DAGPWSRGGPSHRIAAIRRLADIYDRRRAEMADTITAEIGAPISFARRAQVGLPAFMIRA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHH
FCDLAERHPWQETRPGFFGSDVYVRREPVGVVAAIVPWNMPQFLIVTKLIPALLAGCTVV
HHHHHHCCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHCCEEE
LKPAPESPLDALLLAEMISEADLPPGAVSVLPGDAALGAYLAGHRGVDKVSFTGSTAAGR
EECCCCCHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHCCCCCCEEEECCCCHHHH
AVAAACAANLTKVSLELGGKSAALVLDDAPPDKVAAGVRAASLSNSGQICMR
HHHHHHHHHHHEEEEEECCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]