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The map label for this gene is hmp [H]

Identifier: 41409236

GI number: 41409236

Start: 3492132

End: 3492953

Strand: Reverse

Name: hmp [H]

Synonym: MAP3138c

Alternate gene names: 41409236

Gene position: 3492953-3492132 (Counterclockwise)

Preceding gene: 41409237

Following gene: 41409235

Centisome position: 72.32

GC content: 70.19

Gene sequence:

>822_bases
ATGGCCGAACAGCGCACCGCGACGCACGACGGTCCGACGACGGTGACCGACCCCGAACCGGGCGGTACCGACACCGCCGG
ACCCGGTGGCCGGTTGTACGCCTTGCCGCCGCGGGGCCGGTTCGTGCTGACCGACACCGACCGGCAGCTGGTCGCGTTCG
CCGGCGGAAGCGGCATCACACCGGTGTTCTCGCTGCTGCGCACAGCACTGACGGCCGGCACCCGCCGCGCGCGGTTGTTC
TACGCCAACCGAAGCCGCGACGCGGTGATCTTCGACGAGGACCTGGCGGACCTGCAACGACGACATGCCGAGCGCTTCAC
GCTGCACCACCATCTCGACGACGAACGCGGGTTCGCCACGCAGGAGGACATTTCGGCGTTCATCGCGACCGCGGGCGACG
CCGACTTCTATGTGTGCGGGCCGAATGAGTTCATGGACGCGGTGTGCACCGCGCTGCGCGACGCGGGCATCGCGGCCGAG
CGGGTGCACGTCGAGCACTTCGACGTCACCGACGTCGGCGCCGCGGCGCCGGCCGAGGGCCAGGTGCAGCCCGGCGAGGT
CACCATCGTGTTGGACGGGGCCACCACGACCGCCCCGTACCAAGCGGGCAACACGTTGCTGCAGACCGCCCGCATGGCGG
GGCTGCGGGCGCCCTCGTCGTGCGAAATCGGTTCGTGCGGAACGTGTATGGCACGCCTGACGCAGGGGAGTGCCCGGATG
ATCAACAACGACGCGCTCGATCCGGAGGAGGTCGACGACGGCTGGGTGCTGACCTGTCAGGCGCTGCCCACCAGCCCGAC
GGTGCGGGTGGTCTACGAATGA

Upstream 100 bases:

>100_bases
CCATGAGTTGTTCACCGATCACGTCGACGGCTGACCGGCCGCCACCAGGGCTGTATCTAGTACTTGAGATCAATCGCAAG
TAGTTGATACTCTCACGGGG

Downstream 100 bases:

>100_bases
GGGTGGCGGTGGTGACCGGCGGCGCGTCGGGCATGGGCGAGGCGACCTGCCACGAGCTGGGTCGGCGCGGCATGAAAATC
GCCGTGCTCGACGTCAACGA

Product: hypothetical protein

Products: NA

Alternate protein names: Rieske-type oxygenase; RO [H]

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MAEQRTATHDGPTTVTDPEPGGTDTAGPGGRLYALPPRGRFVLTDTDRQLVAFAGGSGITPVFSLLRTALTAGTRRARLF
YANRSRDAVIFDEDLADLQRRHAERFTLHHHLDDERGFATQEDISAFIATAGDADFYVCGPNEFMDAVCTALRDAGIAAE
RVHVEHFDVTDVGAAAPAEGQVQPGEVTIVLDGATTTAPYQAGNTLLQTARMAGLRAPSSCEIGSCGTCMARLTQGSARM
INNDALDPEEVDDGWVLTCQALPTSPTVRVVYE

Sequences:

>Translated_273_residues
MAEQRTATHDGPTTVTDPEPGGTDTAGPGGRLYALPPRGRFVLTDTDRQLVAFAGGSGITPVFSLLRTALTAGTRRARLF
YANRSRDAVIFDEDLADLQRRHAERFTLHHHLDDERGFATQEDISAFIATAGDADFYVCGPNEFMDAVCTALRDAGIAAE
RVHVEHFDVTDVGAAAPAEGQVQPGEVTIVLDGATTTAPYQAGNTLLQTARMAGLRAPSSCEIGSCGTCMARLTQGSARM
INNDALDPEEVDDGWVLTCQALPTSPTVRVVYE
>Mature_272_residues
AEQRTATHDGPTTVTDPEPGGTDTAGPGGRLYALPPRGRFVLTDTDRQLVAFAGGSGITPVFSLLRTALTAGTRRARLFY
ANRSRDAVIFDEDLADLQRRHAERFTLHHHLDDERGFATQEDISAFIATAGDADFYVCGPNEFMDAVCTALRDAGIAAER
VHVEHFDVTDVGAAAPAEGQVQPGEVTIVLDGATTTAPYQAGNTLLQTARMAGLRAPSSCEIGSCGTCMARLTQGSARMI
NNDALDPEEVDDGWVLTCQALPTSPTVRVVYE

Specific function: Catalyzes the opening of ring B of 1,4-androstadiene- 3,17,-dione (ADD) and 4-androstene-3,17-dione (ADD) with concomitant aromatization of ring A. The ring B is subsequently hydroxylated to yield a catechol and then subject to meta- cleavage [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1787658, Length=261, Percent_Identity=29.8850574712644, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1788104, Length=235, Percent_Identity=26.8085106382979, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 29140; Mature: 29008

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEQRTATHDGPTTVTDPEPGGTDTAGPGGRLYALPPRGRFVLTDTDRQLVAFAGGSGIT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCEEEEEECCCCHH
PVFSLLRTALTAGTRRARLFYANRSRDAVIFDEDLADLQRRHAERFTLHHHLDDERGFAT
HHHHHHHHHHHCCCCEEEEEEECCCCCEEEECHHHHHHHHHHHHHEEHHHCCCCCCCCCC
QEDISAFIATAGDADFYVCGPNEFMDAVCTALRDAGIAAERVHVEHFDVTDVGAAAPAEG
HHHHHHHEEECCCCCEEEECCHHHHHHHHHHHHHCCCEEHEEEEEECCCCCCCCCCCCCC
QVQPGEVTIVLDGATTTAPYQAGNTLLQTARMAGLRAPSSCEIGSCGTCMARLTQGSARM
CCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCEE
INNDALDPEEVDDGWVLTCQALPTSPTVRVVYE
ECCCCCCHHHCCCCEEEEEEECCCCCCEEEEEC
>Mature Secondary Structure 
AEQRTATHDGPTTVTDPEPGGTDTAGPGGRLYALPPRGRFVLTDTDRQLVAFAGGSGIT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCEEEEEECCCCHH
PVFSLLRTALTAGTRRARLFYANRSRDAVIFDEDLADLQRRHAERFTLHHHLDDERGFAT
HHHHHHHHHHHCCCCEEEEEEECCCCCEEEECHHHHHHHHHHHHHEEHHHCCCCCCCCCC
QEDISAFIATAGDADFYVCGPNEFMDAVCTALRDAGIAAERVHVEHFDVTDVGAAAPAEG
HHHHHHHEEECCCCCEEEECCHHHHHHHHHHHHHCCCEEHEEEEEECCCCCCCCCCCCCC
QVQPGEVTIVLDGATTTAPYQAGNTLLQTARMAGLRAPSSCEIGSCGTCMARLTQGSARM
CCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCEE
INNDALDPEEVDDGWVLTCQALPTSPTVRVVYE
ECCCCCCHHHCCCCEEEEEEECCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD [C]

Metal ions: Iron-Sulfur [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]