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The map label for this gene is ilvC

Identifier: 41409134

GI number: 41409134

Start: 3377462

End: 3378493

Strand: Reverse

Name: ilvC

Synonym: MAP3036c

Alternate gene names: 41409134

Gene position: 3378493-3377462 (Counterclockwise)

Preceding gene: 41409135

Following gene: 41409131

Centisome position: 69.95

GC content: 66.18

Gene sequence:

>1032_bases
GTGGCTAACCCGTCCGGGGAGACATTGCCGATGTTCTACGACGACGATGCGGACCTGACCATCATCCAGGGTCGCAAGGT
CGGCGTCATCGGATACGGCAGCCAGGGGCATGCGCACTCGCTGAGCCTGCGCGACTCCGGCGTGCAGGTGAAGGTGGGCC
TGAAGGAGGGTTCGAAGTCGCGCGCCAAGGTTTCCGAGCAGGGCCTCGACGTCGACACCCCGGCCGCGGTGGCCAAGTGG
GCCGACGTCATCATGCTGCTGGCCCCCGACACCGCGCAGGCCGACATCTTCAAGAACGACATCGAGCCGAACCTGTCGGA
CGGCGACGCATTGTTTTTCGGTCACGGGCTCAACATCCACTTCGGCCTGATCAAGCCGCCCGCCGAGGTCACCGTCGCGA
TGGTCGCCCCCAAGGGGCCCGGCCACCTGGTGCGCCGCCAGTTCGTCGACGGCAAGGGTGTGCCCTGCCTGATCGCCGTC
GACCAGGACCCGACCGGCAAGGGTGAGGCGCTGGCGCTGTCCTACGCCAAGGCCATCGGCGGCACCCGGGCCGGCGTCAT
CAAGACCACCTTCAAGGACGAGACCGAGACCGACCTGTTCGGTGAGCAGGCCGTGTTGTGCGGTGGCACAGAGGAATTGG
TGAAGGCCGGTTTCGACGTGATGGTCGAGGCGGGCTACCCGCCGGAGATGGCGTACTTCGAGGTGCTGCACGAGCTCAAG
CTGATCGTCGACCTGATGTACGAGGGCGGCATCGCGCGGATGAACTACTCGGTGTCCGACACCGCGGAGTTCGGTGGCTA
TCTGTCCGGGCCCCGCGTCATCGACGCCGGGACCAAGGACCGGATGCGGGAGATCCTGCGCGACATTCAGAACGGCGACT
TCGTCAAGAAGCTGGTCGCCAACGTCGAGGGCGGCAACAAGCAACTCGAGCAGCTGCGCAAGGAGAACGCCGAGCACCCG
ATCGAGGTGGTCGGCAAGCGGCTGCGCGACCTGATGAGCTGGGTCGACCGGCCGATCACCGAGACGGCCTAG

Upstream 100 bases:

>100_bases
GTGAGATCGTCCAATCGGGAGTGGTGTCGCTGTCCCGCGGTCCGCGCGGAATCGGCACGGCCAAGTAAGTTTTCAGCTGC
AACGAGAAGGAGATAGTGAA

Downstream 100 bases:

>100_bases
CGCTTTCGTCGACCGTCACGCTGGCGTGACACTCGGTCACCGGTGTCACGCTGGCGTGACGTTCGTCAGCTAGGAAGCCA
GCCGTCCCGCCGTCTCGACC

Product: ketol-acid reductoisomerase

Products: NA

Alternate protein names: Acetohydroxy-acid isomeroreductase; Alpha-keto-beta-hydroxylacil reductoisomerase [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MANPSGETLPMFYDDDADLTIIQGRKVGVIGYGSQGHAHSLSLRDSGVQVKVGLKEGSKSRAKVSEQGLDVDTPAAVAKW
ADVIMLLAPDTAQADIFKNDIEPNLSDGDALFFGHGLNIHFGLIKPPAEVTVAMVAPKGPGHLVRRQFVDGKGVPCLIAV
DQDPTGKGEALALSYAKAIGGTRAGVIKTTFKDETETDLFGEQAVLCGGTEELVKAGFDVMVEAGYPPEMAYFEVLHELK
LIVDLMYEGGIARMNYSVSDTAEFGGYLSGPRVIDAGTKDRMREILRDIQNGDFVKKLVANVEGGNKQLEQLRKENAEHP
IEVVGKRLRDLMSWVDRPITETA

Sequences:

>Translated_343_residues
MANPSGETLPMFYDDDADLTIIQGRKVGVIGYGSQGHAHSLSLRDSGVQVKVGLKEGSKSRAKVSEQGLDVDTPAAVAKW
ADVIMLLAPDTAQADIFKNDIEPNLSDGDALFFGHGLNIHFGLIKPPAEVTVAMVAPKGPGHLVRRQFVDGKGVPCLIAV
DQDPTGKGEALALSYAKAIGGTRAGVIKTTFKDETETDLFGEQAVLCGGTEELVKAGFDVMVEAGYPPEMAYFEVLHELK
LIVDLMYEGGIARMNYSVSDTAEFGGYLSGPRVIDAGTKDRMREILRDIQNGDFVKKLVANVEGGNKQLEQLRKENAEHP
IEVVGKRLRDLMSWVDRPITETA
>Mature_342_residues
ANPSGETLPMFYDDDADLTIIQGRKVGVIGYGSQGHAHSLSLRDSGVQVKVGLKEGSKSRAKVSEQGLDVDTPAAVAKWA
DVIMLLAPDTAQADIFKNDIEPNLSDGDALFFGHGLNIHFGLIKPPAEVTVAMVAPKGPGHLVRRQFVDGKGVPCLIAVD
QDPTGKGEALALSYAKAIGGTRAGVIKTTFKDETETDLFGEQAVLCGGTEELVKAGFDVMVEAGYPPEMAYFEVLHELKL
IVDLMYEGGIARMNYSVSDTAEFGGYLSGPRVIDAGTKDRMREILRDIQNGDFVKKLVANVEGGNKQLEQLRKENAEHPI
EVVGKRLRDLMSWVDRPITETA

Specific function: Valine and isoleucine biosynthesis; second step. [C]

COG id: COG0059

COG function: function code EH; Ketol-acid reductoisomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketol-acid reductoisomerase family [H]

Homologues:

Organism=Escherichia coli, GI1790210, Length=336, Percent_Identity=33.9285714285714, Blast_Score=154, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6323387, Length=305, Percent_Identity=32.4590163934426, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: 160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013023
- InterPro:   IPR000506
- InterPro:   IPR013328
- InterPro:   IPR013116 [H]

Pfam domain/function: PF01450 IlvC; PF07991 IlvN [H]

EC number: =1.1.1.86 [H]

Molecular weight: Translated: 37013; Mature: 36881

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANPSGETLPMFYDDDADLTIIQGRKVGVIGYGSQGHAHSLSLRDSGVQVKVGLKEGSKS
CCCCCCCEEEEEECCCCCEEEECCCEEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCH
RAKVSEQGLDVDTPAAVAKWADVIMLLAPDTAQADIFKNDIEPNLSDGDALFFGHGLNIH
HHHHHHCCCCCCCHHHHHHHHHEEEEECCCCCCHHHHHCCCCCCCCCCCEEEEECCCEEE
FGLIKPPAEVTVAMVAPKGPGHLVRRQFVDGKGVPCLIAVDQDPTGKGEALALSYAKAIG
EEEECCCCCEEEEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEHHHHHHHC
GTRAGVIKTTFKDETETDLFGEQAVLCGGTEELVKAGFDVMVEAGYPPEMAYFEVLHELK
CCCCCEEEEECCCCCCHHHCCCCEEEECCHHHHHHCCCEEEEECCCCCCHHHHHHHHHHH
LIVDLMYEGGIARMNYSVSDTAEFGGYLSGPRVIDAGTKDRMREILRDIQNGDFVKKLVA
HHHHHHHCCCEEEEECCCCCHHHHCCCCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHH
NVEGGNKQLEQLRKENAEHPIEVVGKRLRDLMSWVDRPITETA
HCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ANPSGETLPMFYDDDADLTIIQGRKVGVIGYGSQGHAHSLSLRDSGVQVKVGLKEGSKS
CCCCCCEEEEEECCCCCEEEECCCEEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCH
RAKVSEQGLDVDTPAAVAKWADVIMLLAPDTAQADIFKNDIEPNLSDGDALFFGHGLNIH
HHHHHHCCCCCCCHHHHHHHHHEEEEECCCCCCHHHHHCCCCCCCCCCCEEEEECCCEEE
FGLIKPPAEVTVAMVAPKGPGHLVRRQFVDGKGVPCLIAVDQDPTGKGEALALSYAKAIG
EEEECCCCCEEEEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEHHHHHHHC
GTRAGVIKTTFKDETETDLFGEQAVLCGGTEELVKAGFDVMVEAGYPPEMAYFEVLHELK
CCCCCEEEEECCCCCCHHHCCCCEEEECCHHHHHHCCCEEEEECCCCCCHHHHHHHHHHH
LIVDLMYEGGIARMNYSVSDTAEFGGYLSGPRVIDAGTKDRMREILRDIQNGDFVKKLVA
HHHHHHHCCCEEEEECCCCCHHHHCCCCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHH
NVEGGNKQLEQLRKENAEHPIEVVGKRLRDLMSWVDRPITETA
HCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA