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The map label for this gene is gpsA

Identifier: 41409118

GI number: 41409118

Start: 3359123

End: 3360124

Strand: Reverse

Name: gpsA

Synonym: MAP3020c

Alternate gene names: 41409118

Gene position: 3360124-3359123 (Counterclockwise)

Preceding gene: 41409122

Following gene: 41409117

Centisome position: 69.57

GC content: 73.05

Gene sequence:

>1002_bases
ATGGGCGCCGGGGCGTGGGGCACCGCGCTGGCCAAGGTGCTCGTCGACGCCGGCGGCCCCGGAACAGAGGTTACGCTGTG
GGCCCGCAGGCCCGAGCTCGCTGAACGGATCAACGCGACCCGATCGAACCCCGACTATCTGCCCGGGACGTCGTTGCCGC
CGGGCATTCACGCCACCGCGGACGCCGGCGAGGCGCTGCGGGACGCGACGACGGTGCTGCTGGGCGTGCCGGCGCAGGCG
ATGCGCGCCAACCTCGAGCGCTGGGCGCCGCTGCTGCGGGACGGGGCGACCCTGGTCAGCCTGGCCAAGGGCATCGAGTT
GGGCACCCTGATGCGGATGAGCCAGGTCATCGTCTCGGTGACCGGCGTCGACCCGGCTCAGGTCGCGGTGATCTCGGGAC
CGAACCTGGCCAGCGAGATCGCCGCGTGCCAGCCCGCCGCGACGGTGGTGGCGTGCAGCGACTCCGGCCGCGCCGTCGCC
CTGCAGCGCATGCTCAACAGCGGATACTTCCGGCCCTACACCAACAGCGATGTGGTCGGCACCGAGATCGGCGGGGCGTG
CAAGAACGTGATCGCGCTGGCCTGCGGGATGGCCGCCGGCGTGGGCCTCGGCGAGAACACCGCGGCGGCCATCATCACCC
GGGGGCTGGCCGAGATCATGCGGCTGGGCATCGCGCTCGGCGCCAAGGGCGCGACGCTGGCCGGGCTGGCCGGGGTGGGC
GACCTGGTCGCCACCTGCAGCTCGCCGCACTCCCGCAACCGTTCGCTGGGCGAGCGGCTCGGCCGCGGGGCAACCATCGG
TTCGGTGCTCGCCGGTAGCCCCGACGGCGGCGACGGGCACGTCGTCGAGGGCGTGACGTCCTGCCAGTCGGTGCTGGCGC
TGGCCGCCAGCTACGACGTGGAAATGCCGCTCACCGACGCGGTGCACCGGGTCTGCCACAAGGGGCTGTCCGTCGATGAG
GCGATGGCGCTGTTGCTGGGCCGGCGCACCAAGCCAGAATGA

Upstream 100 bases:

>100_bases
TGCAAGTGCCGCGTGAGCTACACCGACCACGGACAGGGGGTGGTACATGGCCGGCCCAGGGGGCGGTCCGAAGGCCGGTG
CGGCCGGCGCCGTCACGGTC

Downstream 100 bases:

>100_bases
CGTGGCCGCCACCCGGTAGCCTGTTCAGATTGTGAATGCCAGCCAGCGGGTCCGCGTCGCCGTCGTCTTCGGCGGGCGCA
GCAACGAGCACGCCATCTCG

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MGAGAWGTALAKVLVDAGGPGTEVTLWARRPELAERINATRSNPDYLPGTSLPPGIHATADAGEALRDATTVLLGVPAQA
MRANLERWAPLLRDGATLVSLAKGIELGTLMRMSQVIVSVTGVDPAQVAVISGPNLASEIAACQPAATVVACSDSGRAVA
LQRMLNSGYFRPYTNSDVVGTEIGGACKNVIALACGMAAGVGLGENTAAAIITRGLAEIMRLGIALGAKGATLAGLAGVG
DLVATCSSPHSRNRSLGERLGRGATIGSVLAGSPDGGDGHVVEGVTSCQSVLALAASYDVEMPLTDAVHRVCHKGLSVDE
AMALLLGRRTKPE

Sequences:

>Translated_333_residues
MGAGAWGTALAKVLVDAGGPGTEVTLWARRPELAERINATRSNPDYLPGTSLPPGIHATADAGEALRDATTVLLGVPAQA
MRANLERWAPLLRDGATLVSLAKGIELGTLMRMSQVIVSVTGVDPAQVAVISGPNLASEIAACQPAATVVACSDSGRAVA
LQRMLNSGYFRPYTNSDVVGTEIGGACKNVIALACGMAAGVGLGENTAAAIITRGLAEIMRLGIALGAKGATLAGLAGVG
DLVATCSSPHSRNRSLGERLGRGATIGSVLAGSPDGGDGHVVEGVTSCQSVLALAASYDVEMPLTDAVHRVCHKGLSVDE
AMALLLGRRTKPE
>Mature_332_residues
GAGAWGTALAKVLVDAGGPGTEVTLWARRPELAERINATRSNPDYLPGTSLPPGIHATADAGEALRDATTVLLGVPAQAM
RANLERWAPLLRDGATLVSLAKGIELGTLMRMSQVIVSVTGVDPAQVAVISGPNLASEIAACQPAATVVACSDSGRAVAL
QRMLNSGYFRPYTNSDVVGTEIGGACKNVIALACGMAAGVGLGENTAAAIITRGLAEIMRLGIALGAKGATLAGLAGVGD
LVATCSSPHSRNRSLGERLGRGATIGSVLAGSPDGGDGHVVEGVTSCQSVLALAASYDVEMPLTDAVHRVCHKGLSVDEA
MALLLGRRTKPE

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=351, Percent_Identity=31.9088319088319, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI24307999, Length=350, Percent_Identity=27.4285714285714, Blast_Score=123, Evalue=3e-28,
Organism=Escherichia coli, GI1790037, Length=334, Percent_Identity=41.6167664670659, Blast_Score=225, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI17507425, Length=334, Percent_Identity=29.6407185628743, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI32564399, Length=333, Percent_Identity=27.6276276276276, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI193210136, Length=342, Percent_Identity=27.1929824561404, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI32564403, Length=342, Percent_Identity=27.1929824561404, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI193210134, Length=330, Percent_Identity=25.4545454545455, Blast_Score=88, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6324513, Length=347, Percent_Identity=28.2420749279539, Blast_Score=127, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6320181, Length=352, Percent_Identity=28.4090909090909, Blast_Score=122, Evalue=7e-29,
Organism=Drosophila melanogaster, GI17136204, Length=350, Percent_Identity=29.7142857142857, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17136202, Length=350, Percent_Identity=29.7142857142857, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17136200, Length=350, Percent_Identity=29.7142857142857, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI22026922, Length=334, Percent_Identity=28.1437125748503, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI45551945, Length=329, Percent_Identity=27.9635258358663, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281362270, Length=290, Percent_Identity=28.6206896551724, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24648969, Length=323, Percent_Identity=27.5541795665635, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA1_MYCPA (P61743)

Other databases:

- EMBL:   AE016958
- RefSeq:   NP_961954.1
- ProteinModelPortal:   P61743
- SMR:   P61743
- EnsemblBacteria:   EBMYCT00000037970
- GeneID:   2717789
- GenomeReviews:   AE016958_GR
- KEGG:   mpa:MAP3020c
- NMPDR:   fig|262316.1.peg.3020
- GeneTree:   EBGT00050000016691
- HOGENOM:   HBG586392
- OMA:   SQTLRGN
- ProtClustDB:   PRK00094
- BRENDA:   1.1.1.94
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 33689; Mature: 33558

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 188-188 BINDING 103-103 BINDING 103-103 BINDING 137-137 BINDING 252-252 BINDING 283-283

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAGAWGTALAKVLVDAGGPGTEVTLWARRPELAERINATRSNPDYLPGTSLPPGIHATA
CCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
DAGEALRDATTVLLGVPAQAMRANLERWAPLLRDGATLVSLAKGIELGTLMRMSQVIVSV
CHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHH
TGVDPAQVAVISGPNLASEIAACQPAATVVACSDSGRAVALQRMLNSGYFRPYTNSDVVG
CCCCCCEEEEEECCCHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCC
TEIGGACKNVIALACGMAAGVGLGENTAAAIITRGLAEIMRLGIALGAKGATLAGLAGVG
CHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
DLVATCSSPHSRNRSLGERLGRGATIGSVLAGSPDGGDGHVVEGVTSCQSVLALAASYDV
HHHHHCCCCCCCCHHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
EMPLTDAVHRVCHKGLSVDEAMALLLGRRTKPE
CCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GAGAWGTALAKVLVDAGGPGTEVTLWARRPELAERINATRSNPDYLPGTSLPPGIHATA
CCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
DAGEALRDATTVLLGVPAQAMRANLERWAPLLRDGATLVSLAKGIELGTLMRMSQVIVSV
CHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHH
TGVDPAQVAVISGPNLASEIAACQPAATVVACSDSGRAVALQRMLNSGYFRPYTNSDVVG
CCCCCCEEEEEECCCHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCC
TEIGGACKNVIALACGMAAGVGLGENTAAAIITRGLAEIMRLGIALGAKGATLAGLAGVG
CHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
DLVATCSSPHSRNRSLGERLGRGATIGSVLAGSPDGGDGHVVEGVTSCQSVLALAASYDV
HHHHHCCCCCCCCHHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
EMPLTDAVHRVCHKGLSVDEAMALLLGRRTKPE
CCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA