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The map label for this gene is ddl

Identifier: 41409117

GI number: 41409117

Start: 3357982

End: 3359091

Strand: Reverse

Name: ddl

Synonym: MAP3019c

Alternate gene names: 41409117

Gene position: 3359091-3357982 (Counterclockwise)

Preceding gene: 41409118

Following gene: 41409115

Centisome position: 69.55

GC content: 69.91

Gene sequence:

>1110_bases
GTGAATGCCAGCCAGCGGGTCCGCGTCGCCGTCGTCTTCGGCGGGCGCAGCAACGAGCACGCCATCTCGTGCGTCTCGGC
CGGCAGCATCCTGCGCAACCTCGACCCGCGGCGGTTCGAGGTCGTCGCGATCGGCATCACCCCGCAAGGCTCGTGGGTGC
TCACCGACGGCGACCCGGCCGCGCTGGCGATCAGCGACCGGCAACTGCCCGAGGTGACGTCCGCGTCGGGGACCGAGCTG
GCGCTGCCGGCGGATCCGGGGCGTAGCGGCCAACTGGTTTCCCTTCCCCCCGGAGCCAGTGAGGTGTTGGCCTCCGTCGA
CGTGGTGTTCCCGGTGCTGCACGGCCCGTACGGCGAGGACGGCACGATCCAGGGGCTGCTCGAACTCGCCGGGGTGCCCT
ACGTGGGGGCCGGCGTGTTCGCCAGCGCCGCGGGCATGGACAAGGAATTCACCAAGAAGCTGTTCGCCGCCGAGGGATTG
CCGATCGGCGACTACGCGGTGCTGCGCCCGTCGCAGTCCACACTGTCGCTGCAGGACCGCGAGCGGCTGGGCTTGCCGGT
GTTCGTCAAACCCGCCCGGGGCGGCTCCTCGATCGGCGTCAGCCGGGTCTCGAGCTGGGACGAGCTGGACGCCGCCGTGG
CCGCCGCCCGCGACCACGATCCCAAGGTCATCGTCGAGGCGGCCATCGCCGGCCGGGAGCTGGAGTGCGGGGTGCTCGAA
ATGCCCGACGGCACAGTGCAAGCCAGCACGGTCGGCGAGATCCGGGTGGCCGGGGTGCGCGGGCGTGAGGACTCGTTCTA
CGACTTCGCAACCAAATACCTCGACGACACAGCCGAATTGGACGTGCCCGCCAAGGTCGATGACGAAATCGCCGACGCGG
TACGCGAATTGGCGATCCGCGCATTCAAGGCCGTTGACTGCCAAGGGCTGGCCCGGGTGGACTTCTTCCTCACCGAGACC
GGGCCGGTGCTCAACGAGATCAACACGATGCCCGGCTTCACCACCATCTCGATGTACCCGCGGATGTGGGCGGCCAGCGG
CGTGGACTACCCGAGTCTGCTGGCCACCATGGTGGAGACGGCCCTGGCCCGCGGCGTCGGGCTGCGCTAG

Upstream 100 bases:

>100_bases
TGCCACAAGGGGCTGTCCGTCGATGAGGCGATGGCGCTGTTGCTGGGCCGGCGCACCAAGCCAGAATGACGTGGCCGCCA
CCCGGTAGCCTGTTCAGATT

Downstream 100 bases:

>100_bases
CCGGCGGGCGGCCCGGGGTTGACCGGCGCCGCCGCGATGCGCTGCCCGATCACGTCGGAGAGCCGCTGGATGGGCGCCGG
GCCCGAGCCCGACGGCAGCG

Product: D-alanyl-alanine synthetase A

Products: NA

Alternate protein names: D-Ala-D-Ala ligase; D-alanylalanine synthetase [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MNASQRVRVAVVFGGRSNEHAISCVSAGSILRNLDPRRFEVVAIGITPQGSWVLTDGDPAALAISDRQLPEVTSASGTEL
ALPADPGRSGQLVSLPPGASEVLASVDVVFPVLHGPYGEDGTIQGLLELAGVPYVGAGVFASAAGMDKEFTKKLFAAEGL
PIGDYAVLRPSQSTLSLQDRERLGLPVFVKPARGGSSIGVSRVSSWDELDAAVAAARDHDPKVIVEAAIAGRELECGVLE
MPDGTVQASTVGEIRVAGVRGREDSFYDFATKYLDDTAELDVPAKVDDEIADAVRELAIRAFKAVDCQGLARVDFFLTET
GPVLNEINTMPGFTTISMYPRMWAASGVDYPSLLATMVETALARGVGLR

Sequences:

>Translated_369_residues
MNASQRVRVAVVFGGRSNEHAISCVSAGSILRNLDPRRFEVVAIGITPQGSWVLTDGDPAALAISDRQLPEVTSASGTEL
ALPADPGRSGQLVSLPPGASEVLASVDVVFPVLHGPYGEDGTIQGLLELAGVPYVGAGVFASAAGMDKEFTKKLFAAEGL
PIGDYAVLRPSQSTLSLQDRERLGLPVFVKPARGGSSIGVSRVSSWDELDAAVAAARDHDPKVIVEAAIAGRELECGVLE
MPDGTVQASTVGEIRVAGVRGREDSFYDFATKYLDDTAELDVPAKVDDEIADAVRELAIRAFKAVDCQGLARVDFFLTET
GPVLNEINTMPGFTTISMYPRMWAASGVDYPSLLATMVETALARGVGLR
>Mature_369_residues
MNASQRVRVAVVFGGRSNEHAISCVSAGSILRNLDPRRFEVVAIGITPQGSWVLTDGDPAALAISDRQLPEVTSASGTEL
ALPADPGRSGQLVSLPPGASEVLASVDVVFPVLHGPYGEDGTIQGLLELAGVPYVGAGVFASAAGMDKEFTKKLFAAEGL
PIGDYAVLRPSQSTLSLQDRERLGLPVFVKPARGGSSIGVSRVSSWDELDAAVAAARDHDPKVIVEAAIAGRELECGVLE
MPDGTVQASTVGEIRVAGVRGREDSFYDFATKYLDDTAELDVPAKVDDEIADAVRELAIRAFKAVDCQGLARVDFFLTET
GPVLNEINTMPGFTTISMYPRMWAASGVDYPSLLATMVETALARGVGLR

Specific function: Cell wall formation [H]

COG id: COG1181

COG function: function code M; D-alanine-D-alanine ligase and related ATP-grasp enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Escherichia coli, GI1786579, Length=373, Percent_Identity=44.7721179624665, Blast_Score=290, Evalue=9e-80,
Organism=Escherichia coli, GI1786280, Length=260, Percent_Identity=35.7692307692308, Blast_Score=155, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR000291
- InterPro:   IPR005905
- InterPro:   IPR011095
- InterPro:   IPR011127
- InterPro:   IPR013817
- InterPro:   IPR016185 [H]

Pfam domain/function: PF07478 Dala_Dala_lig_C; PF01820 Dala_Dala_lig_N [H]

EC number: =6.3.2.4 [H]

Molecular weight: Translated: 38872; Mature: 38872

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS50975 ATP_GRASP ; PS00843 DALA_DALA_LIGASE_1 ; PS00844 DALA_DALA_LIGASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASQRVRVAVVFGGRSNEHAISCVSAGSILRNLDPRRFEVVAIGITPQGSWVLTDGDPA
CCCCCEEEEEEEECCCCCCCEEEEEHHHHHHHCCCCCEEEEEEEEECCCCCEEEECCCCC
ALAISDRQLPEVTSASGTELALPADPGRSGQLVSLPPGASEVLASVDVVFPVLHGPYGED
EEEECCCCCCCCCCCCCCEEEECCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCC
GTIQGLLELAGVPYVGAGVFASAAGMDKEFTKKLFAAEGLPIGDYAVLRPSQSTLSLQDR
CHHHHHHHHCCCCEECHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHH
ERLGLPVFVKPARGGSSIGVSRVSSWDELDAAVAAARDHDPKVIVEAAIAGRELECGVLE
HHCCCCEEEEECCCCCCCCHHHCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEE
MPDGTVQASTVGEIRVAGVRGREDSFYDFATKYLDDTAELDVPAKVDDEIADAVRELAIR
CCCCCEEECCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
AFKAVDCQGLARVDFFLTETGPVLNEINTMPGFTTISMYPRMWAASGVDYPSLLATMVET
HHHHCCCCCCEEEEEEEECCCCHHHHHCCCCCEEEEECCCHHHHCCCCCHHHHHHHHHHH
ALARGVGLR
HHHHCCCCC
>Mature Secondary Structure
MNASQRVRVAVVFGGRSNEHAISCVSAGSILRNLDPRRFEVVAIGITPQGSWVLTDGDPA
CCCCCEEEEEEEECCCCCCCEEEEEHHHHHHHCCCCCEEEEEEEEECCCCCEEEECCCCC
ALAISDRQLPEVTSASGTELALPADPGRSGQLVSLPPGASEVLASVDVVFPVLHGPYGED
EEEECCCCCCCCCCCCCCEEEECCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCC
GTIQGLLELAGVPYVGAGVFASAAGMDKEFTKKLFAAEGLPIGDYAVLRPSQSTLSLQDR
CHHHHHHHHCCCCEECHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHH
ERLGLPVFVKPARGGSSIGVSRVSSWDELDAAVAAARDHDPKVIVEAAIAGRELECGVLE
HHCCCCEEEEECCCCCCCCHHHCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEE
MPDGTVQASTVGEIRVAGVRGREDSFYDFATKYLDDTAELDVPAKVDDEIADAVRELAIR
CCCCCEEECCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
AFKAVDCQGLARVDFFLTETGPVLNEINTMPGFTTISMYPRMWAASGVDYPSLLATMVET
HHHHCCCCCCEEEEEEEECCCCHHHHHCCCCCEEEEECCCHHHHCCCCCHHHHHHHHHHH
ALARGVGLR
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA