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The map label for this gene is lepB

Identifier: 41409069

GI number: 41409069

Start: 3305853

End: 3306752

Strand: Reverse

Name: lepB

Synonym: MAP2971c

Alternate gene names: 41409069

Gene position: 3306752-3305853 (Counterclockwise)

Preceding gene: 41409070

Following gene: 41409068

Centisome position: 68.47

GC content: 69.56

Gene sequence:

>900_bases
GTGACCGACACCGCGGATTCCTCTAACCCCCAGTCCCACGCTGGCGACGCAGATCCGAAGGTCTCCACCCGCAACCCGGA
TACCCGCCCCGACGACGACGCCGGCGCGCCCGCACCGGTTCCCGAACCGGGGACCAAGCCCGACGCAGCCGCTCCCACCG
AGGGCTCCAAGCGTTCGACGCTGCGCGAATTCGCCATCCTGGCGGTGATCGCCGTGCTGCTCTACTACGTCATGCTGACC
TTCGTGGCGCGGCCGTACCTGATTCCGTCGGAGTCCATGGAGCCCACGCTGCACGGCTGCACCGGCTGTGTGGGCGACCG
GATCATGGTCGACAAGGTCAGCTACCGCTTCGGCGCCCCGCGCCCCGGCGACGTCATCGTCTTCAAGGGCCCGCCGTCGT
GGAACCTCGGCTACAAGTCGATCCGGTCCAACAACACCGCGCTGCGCTGGGCGCAGAACGCGCTGTCCTTCGTCGGCTTC
GTCCCACCGGACGAGAACGACCTGGTCAAAAGGGTGATCGCGGTCGGGGGGCAGACCGTGCAGTGCCGGGCCGAGACCGG
GCTGACGGTCAACGGCAAGCCGCTGCGCGAGCCCTACCTGGATCGCAACACCATGGCCGCCGACCCGTCGGTGTACCCGT
GCCTGGGCAGTGAGTTCGGCCCGGTCACCGTGCCGGCCGGGCGGCTGTGGGTGATGGGCGACAACCGGACCCACTCCGCG
GATTCGCGCGCGCACTGCACCAGCGTGCCGGCCGAGGCGCTCAAGGGCGTGTTGTGCACCGGGGATCCGGCCTCGGGAAC
CGTGCCGGTGTCCAACGTGATCGGCAAGGCCAGGTTCATCGTGTGGCCGCCGTCCCGCTGGGGCGGGGTGGGATCGGTGA
ACCCGCAACAGGGGCAGTAA

Upstream 100 bases:

>100_bases
TGAACTGCGCGGCAAGAAGGCCAAGATCAAGGAGAAGCGCTGAGCGGCCCGACCGCTCGCCGCTTGCCGGGCCGTAACGT
GCGCTGGCTACGCTGATCTC

Downstream 100 bases:

>100_bases
CCATGGCCACGACGTGGCCGCCCCGGACGGTGATTCGTAAATCGTCGGGTCTGCGCACCCTGGAGTCGGCGCTGTACCGC
AGCGGTCTGGGGCCGGTGGC

Product: hypothetical protein

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MTDTADSSNPQSHAGDADPKVSTRNPDTRPDDDAGAPAPVPEPGTKPDAAAPTEGSKRSTLREFAILAVIAVLLYYVMLT
FVARPYLIPSESMEPTLHGCTGCVGDRIMVDKVSYRFGAPRPGDVIVFKGPPSWNLGYKSIRSNNTALRWAQNALSFVGF
VPPDENDLVKRVIAVGGQTVQCRAETGLTVNGKPLREPYLDRNTMAADPSVYPCLGSEFGPVTVPAGRLWVMGDNRTHSA
DSRAHCTSVPAEALKGVLCTGDPASGTVPVSNVIGKARFIVWPPSRWGGVGSVNPQQGQ

Sequences:

>Translated_299_residues
MTDTADSSNPQSHAGDADPKVSTRNPDTRPDDDAGAPAPVPEPGTKPDAAAPTEGSKRSTLREFAILAVIAVLLYYVMLT
FVARPYLIPSESMEPTLHGCTGCVGDRIMVDKVSYRFGAPRPGDVIVFKGPPSWNLGYKSIRSNNTALRWAQNALSFVGF
VPPDENDLVKRVIAVGGQTVQCRAETGLTVNGKPLREPYLDRNTMAADPSVYPCLGSEFGPVTVPAGRLWVMGDNRTHSA
DSRAHCTSVPAEALKGVLCTGDPASGTVPVSNVIGKARFIVWPPSRWGGVGSVNPQQGQ
>Mature_298_residues
TDTADSSNPQSHAGDADPKVSTRNPDTRPDDDAGAPAPVPEPGTKPDAAAPTEGSKRSTLREFAILAVIAVLLYYVMLTF
VARPYLIPSESMEPTLHGCTGCVGDRIMVDKVSYRFGAPRPGDVIVFKGPPSWNLGYKSIRSNNTALRWAQNALSFVGFV
PPDENDLVKRVIAVGGQTVQCRAETGLTVNGKPLREPYLDRNTMAADPSVYPCLGSEFGPVTVPAGRLWVMGDNRTHSAD
SRAHCTSVPAEALKGVLCTGDPASGTVPVSNVIGKARFIVWPPSRWGGVGSVNPQQGQ

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 31782; Mature: 31651

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: PS00501 SPASE_I_1 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTADSSNPQSHAGDADPKVSTRNPDTRPDDDAGAPAPVPEPGTKPDAAAPTEGSKRST
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
LREFAILAVIAVLLYYVMLTFVARPYLIPSESMEPTLHGCTGCVGDRIMVDKVSYRFGAP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCEEEEEHHHHHCCCC
RPGDVIVFKGPPSWNLGYKSIRSNNTALRWAQNALSFVGFVPPDENDLVKRVIAVGGQTV
CCCCEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCEE
QCRAETGLTVNGKPLREPYLDRNTMAADPSVYPCLGSEFGPVTVPAGRLWVMGDNRTHSA
EEECCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEEEECCCCCCC
DSRAHCTSVPAEALKGVLCTGDPASGTVPVSNVIGKARFIVWPPSRWGGVGSVNPQQGQ
CCCCHHHCCCHHHHCCEEECCCCCCCCEEHHHHCCCEEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDTADSSNPQSHAGDADPKVSTRNPDTRPDDDAGAPAPVPEPGTKPDAAAPTEGSKRST
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
LREFAILAVIAVLLYYVMLTFVARPYLIPSESMEPTLHGCTGCVGDRIMVDKVSYRFGAP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCEEEEEHHHHHCCCC
RPGDVIVFKGPPSWNLGYKSIRSNNTALRWAQNALSFVGFVPPDENDLVKRVIAVGGQTV
CCCCEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCEE
QCRAETGLTVNGKPLREPYLDRNTMAADPSVYPCLGSEFGPVTVPAGRLWVMGDNRTHSA
EEECCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEEEECCCCCCC
DSRAHCTSVPAEALKGVLCTGDPASGTVPVSNVIGKARFIVWPPSRWGGVGSVNPQQGQ
CCCCHHHCCCHHHHCCEEECCCCCCCCEEHHHHCCCEEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]