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The map label for this gene is rnhB

Identifier: 41409068

GI number: 41409068

Start: 3305131

End: 3305850

Strand: Reverse

Name: rnhB

Synonym: MAP2970c

Alternate gene names: 41409068

Gene position: 3305850-3305131 (Counterclockwise)

Preceding gene: 41409069

Following gene: 41409067

Centisome position: 68.45

GC content: 72.5

Gene sequence:

>720_bases
ATGGCCACGACGTGGCCGCCCCGGACGGTGATTCGTAAATCGTCGGGTCTGCGCACCCTGGAGTCGGCGCTGTACCGCAG
CGGTCTGGGGCCGGTGGCCGGCGTGGACGAGGTGGGCCGCGGCGCCTGCGCCGGACCGCTGGTGGTAGCGGCCTGCGTGC
TCGGCCCGGGGAAGCTGGAAAGCCTTGCCGCCCTTGATGATTCGAAGAAGCTGACGGAGAGCGTGCGGGAGCGGCTGTTC
CCGGTGATCCGCCGCTACGCGCTGGCCTATCACGTGGTGTTCATTCCGCCGGCGGAGGTGGACCGTCGCGGCGTGCACGT
CGCCAACATCGAGGGGATGCGCCGTGCCGTGGCCGGGCTGTCGCTGCGGCCCGGCTACGTGCTCAGCGACGGCTTCCGGG
TGCCCGGGTTGGCGGTGCCGTCGCTGCCGGTGATCGGGGGCGACGCCGTCGCGGCGTGCATCGCAGCCGCCAGCGTGCTG
GCCAAGGTCAGCCGGGACCGGTTGATGGTGGCGATGGACGCCGAGCACCCCGGCTACGGCTTCGCCGACCACAAGGGCTA
CAGCACGCCGGCGCACAGCGCGGCGCTGGCCCGGCTGGGCCCGTGCCCGCAGCATCGTCATTCGTTCATCAACGTGCGGC
GGGTGGCCAACGGCTCGGGCGGCCGGGTGGTGGCCGACTGCAAACCGGACCTACCGCTGCAGCGCGACGAGGGCCGGTGA

Upstream 100 bases:

>100_bases
TGCCGGTGTCCAACGTGATCGGCAAGGCCAGGTTCATCGTGTGGCCGCCGTCCCGCTGGGGCGGGGTGGGATCGGTGAAC
CCGCAACAGGGGCAGTAACC

Downstream 100 bases:

>100_bases
GGAAAGATGGGATGGCGAGGGCAGTGTCTCCGAAGAAGGACGTCTGAGCAGATGAGTGGCAGATGAGCGCAGAAGATCTC
GAAAAGTATGAAACCGAGAT

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MATTWPPRTVIRKSSGLRTLESALYRSGLGPVAGVDEVGRGACAGPLVVAACVLGPGKLESLAALDDSKKLTESVRERLF
PVIRRYALAYHVVFIPPAEVDRRGVHVANIEGMRRAVAGLSLRPGYVLSDGFRVPGLAVPSLPVIGGDAVAACIAAASVL
AKVSRDRLMVAMDAEHPGYGFADHKGYSTPAHSAALARLGPCPQHRHSFINVRRVANGSGGRVVADCKPDLPLQRDEGR

Sequences:

>Translated_239_residues
MATTWPPRTVIRKSSGLRTLESALYRSGLGPVAGVDEVGRGACAGPLVVAACVLGPGKLESLAALDDSKKLTESVRERLF
PVIRRYALAYHVVFIPPAEVDRRGVHVANIEGMRRAVAGLSLRPGYVLSDGFRVPGLAVPSLPVIGGDAVAACIAAASVL
AKVSRDRLMVAMDAEHPGYGFADHKGYSTPAHSAALARLGPCPQHRHSFINVRRVANGSGGRVVADCKPDLPLQRDEGR
>Mature_238_residues
ATTWPPRTVIRKSSGLRTLESALYRSGLGPVAGVDEVGRGACAGPLVVAACVLGPGKLESLAALDDSKKLTESVRERLFP
VIRRYALAYHVVFIPPAEVDRRGVHVANIEGMRRAVAGLSLRPGYVLSDGFRVPGLAVPSLPVIGGDAVAACIAAASVLA
KVSRDRLMVAMDAEHPGYGFADHKGYSTPAHSAALARLGPCPQHRHSFINVRRVANGSGGRVVADCKPDLPLQRDEGR

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=183, Percent_Identity=46.9945355191257, Blast_Score=149, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_MYCPA (Q73VP3)

Other databases:

- EMBL:   AE016958
- RefSeq:   NP_961904.1
- ProteinModelPortal:   Q73VP3
- SMR:   Q73VP3
- EnsemblBacteria:   EBMYCT00000037388
- GeneID:   2718023
- GenomeReviews:   AE016958_GR
- KEGG:   mpa:MAP2970c
- NMPDR:   fig|262316.1.peg.2970
- GeneTree:   EBGT00050000016477
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- ProtClustDB:   PRK00015
- BRENDA:   3.1.26.4
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 25227; Mature: 25096

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTWPPRTVIRKSSGLRTLESALYRSGLGPVAGVDEVGRGACAGPLVVAACVLGPGKLE
CCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCCHH
SLAALDDSKKLTESVRERLFPVIRRYALAYHVVFIPPAEVDRRGVHVANIEGMRRAVAGL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCEEECHHHHHHHHHCC
SLRPGYVLSDGFRVPGLAVPSLPVIGGDAVAACIAAASVLAKVSRDRLMVAMDAEHPGYG
CCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCC
FADHKGYSTPAHSAALARLGPCPQHRHSFINVRRVANGSGGRVVADCKPDLPLQRDEGR
CCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
ATTWPPRTVIRKSSGLRTLESALYRSGLGPVAGVDEVGRGACAGPLVVAACVLGPGKLE
CCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCCHH
SLAALDDSKKLTESVRERLFPVIRRYALAYHVVFIPPAEVDRRGVHVANIEGMRRAVAGL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCEEECHHHHHHHHHCC
SLRPGYVLSDGFRVPGLAVPSLPVIGGDAVAACIAAASVLAKVSRDRLMVAMDAEHPGYG
CCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCC
FADHKGYSTPAHSAALARLGPCPQHRHSFINVRRVANGSGGRVVADCKPDLPLQRDEGR
CCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA