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The map label for this gene is pyrH

Identifier: 41409044

GI number: 41409044

Start: 3280960

End: 3281757

Strand: Reverse

Name: pyrH

Synonym: MAP2946c

Alternate gene names: 41409044

Gene position: 3281757-3280960 (Counterclockwise)

Preceding gene: 41409047

Following gene: 41409043

Centisome position: 67.95

GC content: 68.67

Gene sequence:

>798_bases
ATGACGGAGTCCAGGGAGCCCCACGTCGCCGGCTCGGCGGCTCCGAGGCCAGAGCCGGCGAACGGACTGGCTTCCGGCCA
GCCGTCGAGCCGGGCCCGGTATTCGCGAGTGCTGCTCAAGCTGGGCGGCGAGATGTTCGGTGGCGGCCAGGTCGGTTTGG
ATCCCGACGTCGTCGCACAGGTGGCCCGGCAGATCGCCGAGGTGGTCCGCGGCGGCGTCCAGGTGGCGGTGGTGATCGGC
GGCGGCAACTTCTTCCGCGGCGCCCAGCTTCAGCAGCGCGGCATGGAGCGCACCCGTTCGGATTACATGGGCATGCTGGG
CACGGTGATGAACAGCCTGGCGCTGCAAGACTTCCTGGAGAAGGAAGGCATCGTCACCCGGGTGCAGACCGCGATCACCA
TGGGCCAGGTGGCCGAGCCCTATCTGCCGTTGCGCGCGGTGCGCCACCTGGAGAAGGGGCGGGTGGTGATCTTCGGGGCC
GGCATGGGCCTGCCCTACTTCTCCACCGACACCACGGCCGCGCAGCGGGCGCTGGAGATCGGCGCCGAGGTGGTGCTGAT
GGCCAAGGCCGTCGACGGCGTGTTCTCCGCGGATCCCCGGCAATATCCCGAGGCCGAGCTGATCACCGCGATCAGCCACC
GCGAGGTCATCGACCGCGGGCTGCGCGTGGCCGATGCGACGGCGTTCAGCCTGTGCATGGACAATGGCATGCCGATCCTG
GTGTTCAATCTGCTGACCAATGGCAATATCGCCCGCGCGGTCGGCGGTGAGAAGATCGGGACGCTGGTCACCACCTGA

Upstream 100 bases:

>100_bases
TGCACCCCGGCGAGGCCGCGTTGTGCTGCGATGAGGCAGGATGTGAAATGCCGTTCCGGAGAGACTCGTCCCGGGATGGC
ACTCTCATGCGAGGAGTCTG

Downstream 100 bases:

>100_bases
GGAGGAGCGGCGCAGATGATTGACGAGGCTCTCTTCGACGCGGAAGAGAAGATGGAGAAGGCCGTAGCGGTTGCCCGTGA
CGACTTGTCGACCATCCGGA

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MTESREPHVAGSAAPRPEPANGLASGQPSSRARYSRVLLKLGGEMFGGGQVGLDPDVVAQVARQIAEVVRGGVQVAVVIG
GGNFFRGAQLQQRGMERTRSDYMGMLGTVMNSLALQDFLEKEGIVTRVQTAITMGQVAEPYLPLRAVRHLEKGRVVIFGA
GMGLPYFSTDTTAAQRALEIGAEVVLMAKAVDGVFSADPRQYPEAELITAISHREVIDRGLRVADATAFSLCMDNGMPIL
VFNLLTNGNIARAVGGEKIGTLVTT

Sequences:

>Translated_265_residues
MTESREPHVAGSAAPRPEPANGLASGQPSSRARYSRVLLKLGGEMFGGGQVGLDPDVVAQVARQIAEVVRGGVQVAVVIG
GGNFFRGAQLQQRGMERTRSDYMGMLGTVMNSLALQDFLEKEGIVTRVQTAITMGQVAEPYLPLRAVRHLEKGRVVIFGA
GMGLPYFSTDTTAAQRALEIGAEVVLMAKAVDGVFSADPRQYPEAELITAISHREVIDRGLRVADATAFSLCMDNGMPIL
VFNLLTNGNIARAVGGEKIGTLVTT
>Mature_264_residues
TESREPHVAGSAAPRPEPANGLASGQPSSRARYSRVLLKLGGEMFGGGQVGLDPDVVAQVARQIAEVVRGGVQVAVVIGG
GNFFRGAQLQQRGMERTRSDYMGMLGTVMNSLALQDFLEKEGIVTRVQTAITMGQVAEPYLPLRAVRHLEKGRVVIFGAG
MGLPYFSTDTTAAQRALEIGAEVVLMAKAVDGVFSADPRQYPEAELITAISHREVIDRGLRVADATAFSLCMDNGMPILV
FNLLTNGNIARAVGGEKIGTLVTT

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=237, Percent_Identity=45.1476793248945, Blast_Score=204, Evalue=7e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 28140; Mature: 28009

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESREPHVAGSAAPRPEPANGLASGQPSSRARYSRVLLKLGGEMFGGGQVGLDPDVVAQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
VARQIAEVVRGGVQVAVVIGGGNFFRGAQLQQRGMERTRSDYMGMLGTVMNSLALQDFLE
HHHHHHHHHHCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEGIVTRVQTAITMGQVAEPYLPLRAVRHLEKGRVVIFGAGMGLPYFSTDTTAAQRALEI
HCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHH
GAEVVLMAKAVDGVFSADPRQYPEAELITAISHREVIDRGLRVADATAFSLCMDNGMPIL
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEE
VFNLLTNGNIARAVGGEKIGTLVTT
EEEECCCCCEEECCCCCCCCCEECC
>Mature Secondary Structure 
TESREPHVAGSAAPRPEPANGLASGQPSSRARYSRVLLKLGGEMFGGGQVGLDPDVVAQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
VARQIAEVVRGGVQVAVVIGGGNFFRGAQLQQRGMERTRSDYMGMLGTVMNSLALQDFLE
HHHHHHHHHHCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEGIVTRVQTAITMGQVAEPYLPLRAVRHLEKGRVVIFGAGMGLPYFSTDTTAAQRALEI
HCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHH
GAEVVLMAKAVDGVFSADPRQYPEAELITAISHREVIDRGLRVADATAFSLCMDNGMPIL
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEE
VFNLLTNGNIARAVGGEKIGTLVTT
EEEECCCCCEEECCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA