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The map label for this gene is glnA4

Identifier: 41409029

GI number: 41409029

Start: 3264786

End: 3266171

Strand: Reverse

Name: glnA4

Synonym: MAP2931c

Alternate gene names: 41409029

Gene position: 3266171-3264786 (Counterclockwise)

Preceding gene: 41409030

Following gene: 41409028

Centisome position: 67.63

GC content: 70.35

Gene sequence:

>1386_bases
CTGACCGGTTCCGATACCGCGATGCTCTCGCTCGCCGCGCTGGACCGACTGGTGGCCGCCGGCGCGCCGGAAACGCGGGT
GGACACCGTCATCGTGGCCTTCCCCGACATGCAGGGCCGGCTGGTCGGCAAGCGGATGGACGCGCGGCTGTTCGTCGACG
AGGCGGCCGCCACCGGGGTCGAGTGTTGCGGCTACCTGCTGGCCGTCGACGTCGACATGAACACCGTGGGCGGCTATGCG
ATCTCGGGCTGGGACACCGGGTACGGCGACCTGGTGATGCGCCCGGACCTGTCCACCCTGCGCCGCATTCCCTGGCTGCC
CGGGACGGCGCTGGTGATCGCCGACGTGGTGGGGGCCGACGGCAGCCCGGTCGCGGTGTCGCCGCGGGCCGTGCTGCGCC
GCCAGCTCGACCGGCTGGCCGGGCGGGGGCTGTTCGCCGACGCCGCGACGGAGCTGGAATTCATGGTGTTCGACGAGCCG
TACCGCCAGGCGTGGGCCAGCGGCTACCGCGGGCTGACCCCGGCCAGTGACTACAACATCGACTACGCGATCTCGGCGTC
GTCGCGCATGGAGCCGCTGCTGCGCGACATCCGGCGCGGAATGGCCGGTGCGGGACTGCGATTCGAGTCCGTGAAGGGTG
AATGCAACCGCGGCCAGCAGGAGATCGGCTTCCGCTACGACGAGGCGCTGCGGACCTGCGACAACCACGTCATCTACAAG
AACGGGGCCAAGGAGATCGCCGATCAGCACGGCAAGAGCCTGACATTCATGGCGAAATACGATGAGCGCGAAGGCAACAG
CTGCCGCGTTCACCTTTCGCTGCGCGACGCCCAGGGCGGGGCGGCGTTCGCCGACCCCAGCCGCCCGCACGGCATGTCGA
CGATGTTCTGCAGCTTCCTGGCCGGCCTGCTGGCCACCATGGCAGACTTCACGCTGTTCTACGCGCCGAACATCAACTCC
TACAAGCGATTCGCCGATGAGAGTTTCGCGCCCACCGCGCTGGCCTGGGGATTGGACAACCGCACCTGCGCGCTGCGGGT
GGTCGGCCACGGCGCGCACACCCGCGTCGAGTGCCGGGTTCCCGGCGGCGATGTCAACCCGTATCTGGCGGTGGCGGCGA
TCGTCGCCGGCGGGCTGTACGGTATCGAGCAGGGCCTGGCGCTGCCGGAACCCTGCGCGGGCAACGCCTACCGCGCCCGC
GGCGTCGGCCGGCTGCCGGGCACCCTGGCCGAGGCGGCGGCGCTGTTCGAGCACTCGGCGCTGGCGCGGCAGGTGTTCGG
CGACGACGTCGTCGCGCACTACCTGAACAACGCCCGGGTCGAGCTGGCGGCGTTTCACGCCGCGGCCACCGATTGGGAGA
GGATGCGTGGTTTTGAACGGCTCTGA

Upstream 100 bases:

>100_bases
GCGCACGGTGCAGGAGTCGACGGCGCAACTGGCCGCCGAGATCATTCTGCGCACCAGCACCTGGTAGCCCGCGACGGTCA
TGGCCAGTGAAGACAGCGCG

Downstream 100 bases:

>100_bases
GCCCCTTGGGGGCGATCCGCCGCGGCGGCCGGTGGTGGGCCTGACGGCGTATCTGGAACGGGTGCAGACCGGGATCTGGG
ACATCCCCGCCGGGTACCTG

Product: GlnA4

Products: NA

Alternate protein names: GS; Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MTGSDTAMLSLAALDRLVAAGAPETRVDTVIVAFPDMQGRLVGKRMDARLFVDEAAATGVECCGYLLAVDVDMNTVGGYA
ISGWDTGYGDLVMRPDLSTLRRIPWLPGTALVIADVVGADGSPVAVSPRAVLRRQLDRLAGRGLFADAATELEFMVFDEP
YRQAWASGYRGLTPASDYNIDYAISASSRMEPLLRDIRRGMAGAGLRFESVKGECNRGQQEIGFRYDEALRTCDNHVIYK
NGAKEIADQHGKSLTFMAKYDEREGNSCRVHLSLRDAQGGAAFADPSRPHGMSTMFCSFLAGLLATMADFTLFYAPNINS
YKRFADESFAPTALAWGLDNRTCALRVVGHGAHTRVECRVPGGDVNPYLAVAAIVAGGLYGIEQGLALPEPCAGNAYRAR
GVGRLPGTLAEAAALFEHSALARQVFGDDVVAHYLNNARVELAAFHAAATDWERMRGFERL

Sequences:

>Translated_461_residues
MTGSDTAMLSLAALDRLVAAGAPETRVDTVIVAFPDMQGRLVGKRMDARLFVDEAAATGVECCGYLLAVDVDMNTVGGYA
ISGWDTGYGDLVMRPDLSTLRRIPWLPGTALVIADVVGADGSPVAVSPRAVLRRQLDRLAGRGLFADAATELEFMVFDEP
YRQAWASGYRGLTPASDYNIDYAISASSRMEPLLRDIRRGMAGAGLRFESVKGECNRGQQEIGFRYDEALRTCDNHVIYK
NGAKEIADQHGKSLTFMAKYDEREGNSCRVHLSLRDAQGGAAFADPSRPHGMSTMFCSFLAGLLATMADFTLFYAPNINS
YKRFADESFAPTALAWGLDNRTCALRVVGHGAHTRVECRVPGGDVNPYLAVAAIVAGGLYGIEQGLALPEPCAGNAYRAR
GVGRLPGTLAEAAALFEHSALARQVFGDDVVAHYLNNARVELAAFHAAATDWERMRGFERL
>Mature_460_residues
TGSDTAMLSLAALDRLVAAGAPETRVDTVIVAFPDMQGRLVGKRMDARLFVDEAAATGVECCGYLLAVDVDMNTVGGYAI
SGWDTGYGDLVMRPDLSTLRRIPWLPGTALVIADVVGADGSPVAVSPRAVLRRQLDRLAGRGLFADAATELEFMVFDEPY
RQAWASGYRGLTPASDYNIDYAISASSRMEPLLRDIRRGMAGAGLRFESVKGECNRGQQEIGFRYDEALRTCDNHVIYKN
GAKEIADQHGKSLTFMAKYDEREGNSCRVHLSLRDAQGGAAFADPSRPHGMSTMFCSFLAGLLATMADFTLFYAPNINSY
KRFADESFAPTALAWGLDNRTCALRVVGHGAHTRVECRVPGGDVNPYLAVAAIVAGGLYGIEQGLALPEPCAGNAYRARG
VGRLPGTLAEAAALFEHSALARQVFGDDVVAHYLNNARVELAAFHAAATDWERMRGFERL

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=453, Percent_Identity=26.0485651214128, Blast_Score=131, Evalue=1e-30,
Organism=Escherichia coli, GI87081870, Length=438, Percent_Identity=31.5068493150685, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1790301, Length=376, Percent_Identity=28.1914893617021, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 49766; Mature: 49635

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGSDTAMLSLAALDRLVAAGAPETRVDTVIVAFPDMQGRLVGKRMDARLFVDEAAATGV
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEECCCCCCCEEEEHHHHHHHH
ECCGYLLAVDVDMNTVGGYAISGWDTGYGDLVMRPDLSTLRRIPWLPGTALVIADVVGAD
HHCCEEEEEEECCCCCCCEEEECCCCCCCCEEECCCHHHHHHCCCCCCCHHHHHHHHCCC
GSPVAVSPRAVLRRQLDRLAGRGLFADAATELEFMVFDEPYRQAWASGYRGLTPASDYNI
CCCEEECHHHHHHHHHHHHHCCCCEECCCCCEEEEEECCHHHHHHHCCCCCCCCCCCCCE
DYAISASSRMEPLLRDIRRGMAGAGLRFESVKGECNRGQQEIGFRYDEALRTCDNHVIYK
EEEECCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHCCHHHHHHHHHCCCEEEE
NGAKEIADQHGKSLTFMAKYDEREGNSCRVHLSLRDAQGGAAFADPSRPHGMSTMFCSFL
CCHHHHHHHCCCEEEEEEEECCCCCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHH
AGLLATMADFTLFYAPNINSYKRFADESFAPTALAWGLDNRTCALRVVGHGAHTRVECRV
HHHHHHHHHCEEEECCCCCHHHHHHCCCCCCCEEEECCCCCEEEEEEEECCCCEEEEEEC
PGGDVNPYLAVAAIVAGGLYGIEQGLALPEPCAGNAYRARGVGRLPGTLAEAAALFEHSA
CCCCCCHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHH
LARQVFGDDVVAHYLNNARVELAAFHAAATDWERMRGFERL
HHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCHHHHHHCCCC
>Mature Secondary Structure 
TGSDTAMLSLAALDRLVAAGAPETRVDTVIVAFPDMQGRLVGKRMDARLFVDEAAATGV
CCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEECCCCCCCEEEEHHHHHHHH
ECCGYLLAVDVDMNTVGGYAISGWDTGYGDLVMRPDLSTLRRIPWLPGTALVIADVVGAD
HHCCEEEEEEECCCCCCCEEEECCCCCCCCEEECCCHHHHHHCCCCCCCHHHHHHHHCCC
GSPVAVSPRAVLRRQLDRLAGRGLFADAATELEFMVFDEPYRQAWASGYRGLTPASDYNI
CCCEEECHHHHHHHHHHHHHCCCCEECCCCCEEEEEECCHHHHHHHCCCCCCCCCCCCCE
DYAISASSRMEPLLRDIRRGMAGAGLRFESVKGECNRGQQEIGFRYDEALRTCDNHVIYK
EEEECCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHCCHHHHHHHHHCCCEEEE
NGAKEIADQHGKSLTFMAKYDEREGNSCRVHLSLRDAQGGAAFADPSRPHGMSTMFCSFL
CCHHHHHHHCCCEEEEEEEECCCCCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHH
AGLLATMADFTLFYAPNINSYKRFADESFAPTALAWGLDNRTCALRVVGHGAHTRVECRV
HHHHHHHHHCEEEECCCCCHHHHHHCCCCCCCEEEECCCCCEEEEEEEECCCCEEEEEEC
PGGDVNPYLAVAAIVAGGLYGIEQGLALPEPCAGNAYRARGVGRLPGTLAEAAALFEHSA
CCCCCCHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHH
LARQVFGDDVVAHYLNNARVELAAFHAAATDWERMRGFERL
HHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]