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The map label for this gene is mqo

Identifier: 41409019

GI number: 41409019

Start: 3253814

End: 3255319

Strand: Reverse

Name: mqo

Synonym: MAP2921c

Alternate gene names: 41409019

Gene position: 3255319-3253814 (Counterclockwise)

Preceding gene: 41409026

Following gene: 41409018

Centisome position: 67.4

GC content: 68.92

Gene sequence:

>1506_bases
GTGTCATCGCTAGCCAGGACCACCCGCGCGGACGTCGTGCTGGTGGGCGCGGGCATCATGAGCGCCACGCTGGGCGCGTT
GCTGCGGCGGCTGCAGCCGGATTGGTCGATGACCTTCGTCGAGCGCCTGGACGCGGTCGCCGCTGAGAGCAGCAGCCCGT
GGAACAACGCCGGCACCGGGCATTCGGCGCTGTGCGAGCTCAACTACACCCCGCAGCGCGCCGACGGCTCCATCGACATC
GCCAAAGCGGTGCGCATCAACGAGCAGTTCCAGGTGACCCGCCAATTCTGGGCGTATGCCGTGGAGAACGGCATGCTGAC
CGATCGGGGCTTCGTGACCCCGATCCCGCACGCGAGTTTCGTGCGCGGGGCGCGGGCCGTCGAGTATCTGCGGCGCCGGC
AGCAGGCGCTGGCGCCCAACCCGTTGTTCGCCGGCATCGAATTGATCGAGGACGCCGACGAGTTCGCCCGCCGGCTGCCG
TTGATGGCCGACCGGCGGGACTTCTCCGAACCGACCGCGCTGAATTGGGCGCGCCACGGCACCGACGTCGACTTCGGCGC
GCTGTCGCGACAGCTGATCGGGTTCTGCGTGCGCGGCGGCGCGACGGCGCTGTTCGGCCATCAGGTGCACAACCTGACGC
GGGAGTCCGACGGCAGCTGGACGTTGCTGATCCGCAACCGCCGGACCGGCGAAAAGCACTGGTGCAACGCCAAATTCGTG
TTGGTCGGGGCCGGCGGTGACGCGCTGCCGCTGCTGCAGAAGTCGGGTATCGGCGAGGCTCGCGGATTCGCGGGGTTCCC
GATCGGCGGTCGGTTCCTGCGCGCCGACAATCCCGTGCTTACCGAGGCGCACCGGGCCAAGGTGTACGGGGCTCCAGCGC
CGGGGGCCCCGCCGCTGGGAGCGTTGCATCTGGACCTGCGCTACGTCAACGGCAAGCCGTGGCTGGTGTTCGGGCCGTAT
GCCGGCTGGTCGCCGAAGTTCTTGAAACACGGGCACTTCACCGATCTGCCCCGCTCGGTGCGGCCGCACAATCTGGTCGC
GCTGCTCGGCGTCGGCGTCACCCAGCTGACGTTGCTGCGGTACCTGATCGGCCAGTTGCGGCTGTCCGCGCCGGACCGGA
TGCGGATGCTGCGCGAATTCGCGCCCACCGCAGTGGATTCGGACTGGGAGCTGACGGTGGCCGGTCAGCGGGTGCAGGTG
ATCCGGCGCGATCGGCGCCGCGGCGGCGTGCTCGACTTCGACACCACCGTGGTGGCGGCCGGCGACGGCAGCATCGCGGG
GTTGCTCGGCGGCTCGCCGGGAGCGTCGACGGCGGTGCCGATCATGCTCGATGTGCTGCAGCGCTGTTTCGCTGACCGTT
ATCGGTCGTGGCTGCCCGCGCTCAAGGAGATGGTTCCCTCGCTGGGCGTGACGCTGTCCGACGAGCCGGCGCTGTATGAG
GAAGTCTATTCATGGGGAACGAAGATCCTGGGACTGGACGAGTTGGATGAGGAGCGCCCTAAGTGA

Upstream 100 bases:

>100_bases
AGCTTTTGCCGGCCGCGGCGACCCCGCGCGTGGTTCGCGTCGCTTTGCCACCGGATAACCTGAGGATCGGCATGCCTCGA
GGAAAAGGACCAACAAGCCG

Downstream 100 bases:

>100_bases
CACGCGCCGACGACGATGCAGAGCGCAGCGATGAGGAGGAGCGGCGCAGATGACTCGCGCCGACGACGATGCAGAGCGCA
GCGATGAGGAGGAGCGGCGC

Product: malate:quinone oxidoreductase

Products: NA

Alternate protein names: MQO; Malate dehydrogenase [quinone]

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MSSLARTTRADVVLVGAGIMSATLGALLRRLQPDWSMTFVERLDAVAAESSSPWNNAGTGHSALCELNYTPQRADGSIDI
AKAVRINEQFQVTRQFWAYAVENGMLTDRGFVTPIPHASFVRGARAVEYLRRRQQALAPNPLFAGIELIEDADEFARRLP
LMADRRDFSEPTALNWARHGTDVDFGALSRQLIGFCVRGGATALFGHQVHNLTRESDGSWTLLIRNRRTGEKHWCNAKFV
LVGAGGDALPLLQKSGIGEARGFAGFPIGGRFLRADNPVLTEAHRAKVYGAPAPGAPPLGALHLDLRYVNGKPWLVFGPY
AGWSPKFLKHGHFTDLPRSVRPHNLVALLGVGVTQLTLLRYLIGQLRLSAPDRMRMLREFAPTAVDSDWELTVAGQRVQV
IRRDRRRGGVLDFDTTVVAAGDGSIAGLLGGSPGASTAVPIMLDVLQRCFADRYRSWLPALKEMVPSLGVTLSDEPALYE
EVYSWGTKILGLDELDEERPK

Sequences:

>Translated_501_residues
MSSLARTTRADVVLVGAGIMSATLGALLRRLQPDWSMTFVERLDAVAAESSSPWNNAGTGHSALCELNYTPQRADGSIDI
AKAVRINEQFQVTRQFWAYAVENGMLTDRGFVTPIPHASFVRGARAVEYLRRRQQALAPNPLFAGIELIEDADEFARRLP
LMADRRDFSEPTALNWARHGTDVDFGALSRQLIGFCVRGGATALFGHQVHNLTRESDGSWTLLIRNRRTGEKHWCNAKFV
LVGAGGDALPLLQKSGIGEARGFAGFPIGGRFLRADNPVLTEAHRAKVYGAPAPGAPPLGALHLDLRYVNGKPWLVFGPY
AGWSPKFLKHGHFTDLPRSVRPHNLVALLGVGVTQLTLLRYLIGQLRLSAPDRMRMLREFAPTAVDSDWELTVAGQRVQV
IRRDRRRGGVLDFDTTVVAAGDGSIAGLLGGSPGASTAVPIMLDVLQRCFADRYRSWLPALKEMVPSLGVTLSDEPALYE
EVYSWGTKILGLDELDEERPK
>Mature_500_residues
SSLARTTRADVVLVGAGIMSATLGALLRRLQPDWSMTFVERLDAVAAESSSPWNNAGTGHSALCELNYTPQRADGSIDIA
KAVRINEQFQVTRQFWAYAVENGMLTDRGFVTPIPHASFVRGARAVEYLRRRQQALAPNPLFAGIELIEDADEFARRLPL
MADRRDFSEPTALNWARHGTDVDFGALSRQLIGFCVRGGATALFGHQVHNLTRESDGSWTLLIRNRRTGEKHWCNAKFVL
VGAGGDALPLLQKSGIGEARGFAGFPIGGRFLRADNPVLTEAHRAKVYGAPAPGAPPLGALHLDLRYVNGKPWLVFGPYA
GWSPKFLKHGHFTDLPRSVRPHNLVALLGVGVTQLTLLRYLIGQLRLSAPDRMRMLREFAPTAVDSDWELTVAGQRVQVI
RRDRRRGGVLDFDTTVVAAGDGSIAGLLGGSPGASTAVPIMLDVLQRCFADRYRSWLPALKEMVPSLGVTLSDEPALYEE
VYSWGTKILGLDELDEERPK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0579

COG function: function code R; Predicted dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MQO family

Homologues:

Organism=Escherichia coli, GI1788539, Length=487, Percent_Identity=48.6652977412731, Blast_Score=462, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MQO_MYCPA (Q73VU0)

Other databases:

- EMBL:   AE016958
- RefSeq:   NP_961855.1
- ProteinModelPortal:   Q73VU0
- EnsemblBacteria:   EBMYCT00000037273
- GeneID:   2721811
- GenomeReviews:   AE016958_GR
- KEGG:   mpa:MAP2921c
- NMPDR:   fig|262316.1.peg.2921
- GeneTree:   EBGT00050000015585
- HOGENOM:   HBG289663
- OMA:   NALKEYF
- ProtClustDB:   PRK05257
- BRENDA:   1.1.99.16
- HAMAP:   MF_00212
- InterPro:   IPR006231
- TIGRFAMs:   TIGR01320

Pfam domain/function: PF06039 Mqo

EC number: =1.1.5.4

Molecular weight: Translated: 54937; Mature: 54806

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLARTTRADVVLVGAGIMSATLGALLRRLQPDWSMTFVERLDAVAAESSSPWNNAGTG
CCCHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
HSALCELNYTPQRADGSIDIAKAVRINEQFQVTRQFWAYAVENGMLTDRGFVTPIPHASF
CCEEEEECCCCCCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
VRGARAVEYLRRRQQALAPNPLFAGIELIEDADEFARRLPLMADRRDFSEPTALNWARHG
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCC
TDVDFGALSRQLIGFCVRGGATALFGHQVHNLTRESDGSWTLLIRNRRTGEKHWCNAKFV
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEE
LVGAGGDALPLLQKSGIGEARGFAGFPIGGRFLRADNPVLTEAHRAKVYGAPAPGAPPLG
EEECCCCCCHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHEEECCCCCCCCCCC
ALHLDLRYVNGKPWLVFGPYAGWSPKFLKHGHFTDLPRSVRPHNLVALLGVGVTQLTLLR
EEEEEEEEECCCEEEEECCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHH
YLIGQLRLSAPDRMRMLREFAPTAVDSDWELTVAGQRVQVIRRDRRRGGVLDFDTTVVAA
HHHHHHCCCCCHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHCCCCEEECCEEEEE
GDGSIAGLLGGSPGASTAVPIMLDVLQRCFADRYRSWLPALKEMVPSLGVTLSDEPALYE
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHH
EVYSWGTKILGLDELDEERPK
HHHHHCCEEECCHHHHHCCCC
>Mature Secondary Structure 
SSLARTTRADVVLVGAGIMSATLGALLRRLQPDWSMTFVERLDAVAAESSSPWNNAGTG
CCHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
HSALCELNYTPQRADGSIDIAKAVRINEQFQVTRQFWAYAVENGMLTDRGFVTPIPHASF
CCEEEEECCCCCCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
VRGARAVEYLRRRQQALAPNPLFAGIELIEDADEFARRLPLMADRRDFSEPTALNWARHG
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCC
TDVDFGALSRQLIGFCVRGGATALFGHQVHNLTRESDGSWTLLIRNRRTGEKHWCNAKFV
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEE
LVGAGGDALPLLQKSGIGEARGFAGFPIGGRFLRADNPVLTEAHRAKVYGAPAPGAPPLG
EEECCCCCCHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHEEECCCCCCCCCCC
ALHLDLRYVNGKPWLVFGPYAGWSPKFLKHGHFTDLPRSVRPHNLVALLGVGVTQLTLLR
EEEEEEEEECCCEEEEECCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHH
YLIGQLRLSAPDRMRMLREFAPTAVDSDWELTVAGQRVQVIRRDRRRGGVLDFDTTVVAA
HHHHHHCCCCCHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHCCCCEEECCEEEEE
GDGSIAGLLGGSPGASTAVPIMLDVLQRCFADRYRSWLPALKEMVPSLGVTLSDEPALYE
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHH
EVYSWGTKILGLDELDEERPK
HHHHHCCEEECCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA