| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
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The map label for this gene is fabG [H]
Identifier: 41409026
GI number: 41409026
Start: 3261904
End: 3262680
Strand: Reverse
Name: fabG [H]
Synonym: MAP2928c
Alternate gene names: 41409026
Gene position: 3262680-3261904 (Counterclockwise)
Preceding gene: 41409027
Following gene: 41409019
Centisome position: 67.55
GC content: 70.66
Gene sequence:
>777_bases GTGATGGACCTGACGCAACGGTTGGCGGGCCGGGTGGCGGTCATCACCGGCGCCGGCGGCGGGATCGGGCTGGCCGCGGC GCGCCGGATGCACGCCGAAGGCGCCACCATCGTGGTGGCCGACATCGACGCCGACGCCGGGGCGGCGGCCGCCGACGAAC TGTCCGGCCTGTTCGTGCCGACCGACGTCGCCGACGAGGACGCGGTCAACGCGCTGTTCGACACCGCGGCGCGCCGCTAC GGGCGCATCGACATCGCGTTCAACAACGCCGGCATCTCACCCCCCGACGACGACGTCATCGAGAACACCGAACCGCCGGC CTGGCAACGCGTCCAGGACGTCAACCTGAAGTCGGTGTATCTGTGCTGCCGGGCGGCATTGCGGCACATGGTTTCCGCGC GACGCGGGTCGATCATCAACACGGCGTCGTTCGTCGCGGTGATGGGCTCGGCGACGTCGCAGATCTCCTACACCGCCGCC AAGGGCGGGGTACTGGCCCTGTCGCGGGAACTCGGGGTGCAGTTCGCCCGGCAGGGCATCCGGGTGAACGCGCTGTGCCC CGGGCCGGTCAACACCCCGCTGCTGCAGGAGCTGTTCGCCAAAGACCCGCAGCGCGCCGCCCGCCGGCTGGTGCACGTGC CGGTCGGCCGCTTCGCCGAACCTGGCGAAATCGCCGCTGCGGCAGCATTCTTGGCCAGCGATGACGCGTCCTTCATCACC GCGTCCACGTTCTTGGTCGACGGCGGCATCAGCGCGGCGTACGTGACCCCGCTCTAA
Upstream 100 bases:
>100_bases GCGGGTTCAAACAGTCGGGGCTGGGCCGCGAACTGGGACCGGACGCCCCGGCGCAGTTCACCGAGACCAAGAACGTTTTC ATCGCGATCGACGAGGAGCC
Downstream 100 bases:
>100_bases CCGCCGGACTCGCCGGCCGCGTGCGGGCCCGCCGGCTCGCCGGGCGGCACCAGCCGGATGTGCTCGCCCGCCCGGTCCGG GCGCGGCTGCCGCGCCAGCG
Product: short chain dehydrogenase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 258; Mature: 258
Protein sequence:
>258_residues MMDLTQRLAGRVAVITGAGGGIGLAAARRMHAEGATIVVADIDADAGAAAADELSGLFVPTDVADEDAVNALFDTAARRY GRIDIAFNNAGISPPDDDVIENTEPPAWQRVQDVNLKSVYLCCRAALRHMVSARRGSIINTASFVAVMGSATSQISYTAA KGGVLALSRELGVQFARQGIRVNALCPGPVNTPLLQELFAKDPQRAARRLVHVPVGRFAEPGEIAAAAAFLASDDASFIT ASTFLVDGGISAAYVTPL
Sequences:
>Translated_258_residues MMDLTQRLAGRVAVITGAGGGIGLAAARRMHAEGATIVVADIDADAGAAAADELSGLFVPTDVADEDAVNALFDTAARRY GRIDIAFNNAGISPPDDDVIENTEPPAWQRVQDVNLKSVYLCCRAALRHMVSARRGSIINTASFVAVMGSATSQISYTAA KGGVLALSRELGVQFARQGIRVNALCPGPVNTPLLQELFAKDPQRAARRLVHVPVGRFAEPGEIAAAAAFLASDDASFIT ASTFLVDGGISAAYVTPL >Mature_258_residues MMDLTQRLAGRVAVITGAGGGIGLAAARRMHAEGATIVVADIDADAGAAAADELSGLFVPTDVADEDAVNALFDTAARRY GRIDIAFNNAGISPPDDDVIENTEPPAWQRVQDVNLKSVYLCCRAALRHMVSARRGSIINTASFVAVMGSATSQISYTAA KGGVLALSRELGVQFARQGIRVNALCPGPVNTPLLQELFAKDPQRAARRLVHVPVGRFAEPGEIAAAAAFLASDDASFIT ASTFLVDGGISAAYVTPL
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI59889578, Length=225, Percent_Identity=37.3333333333333, Blast_Score=136, Evalue=2e-32, Organism=Homo sapiens, GI15277342, Length=263, Percent_Identity=32.319391634981, Blast_Score=125, Evalue=3e-29, Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=34.156378600823, Blast_Score=125, Evalue=5e-29, Organism=Homo sapiens, GI66933014, Length=248, Percent_Identity=33.0645161290323, Blast_Score=116, Evalue=3e-26, Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=30.3149606299213, Blast_Score=111, Evalue=8e-25, Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=29.0697674418605, Blast_Score=108, Evalue=4e-24, Organism=Homo sapiens, GI4758504, Length=262, Percent_Identity=32.824427480916, Blast_Score=107, Evalue=1e-23, Organism=Homo sapiens, GI31542939, Length=204, Percent_Identity=32.843137254902, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=31.4741035856574, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI83715985, Length=257, Percent_Identity=31.1284046692607, Blast_Score=92, Evalue=5e-19, Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=28.8617886178862, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI10190704, Length=252, Percent_Identity=31.7460317460317, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI109715829, Length=246, Percent_Identity=28.4552845528455, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI126723750, Length=257, Percent_Identity=28.4046692607004, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI4504505, Length=192, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI4503301, Length=255, Percent_Identity=29.4117647058824, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=30.5263157894737, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=31.7919075144509, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI209862901, Length=206, Percent_Identity=29.6116504854369, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI19923983, Length=206, Percent_Identity=29.6116504854369, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI126723191, Length=189, Percent_Identity=28.042328042328, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI7706318, Length=205, Percent_Identity=24.8780487804878, Blast_Score=64, Evalue=1e-10, Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=35.8024691358025, Blast_Score=142, Evalue=2e-35, Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=33.8461538461538, Blast_Score=133, Evalue=9e-33, Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=34.9593495934959, Blast_Score=124, Evalue=6e-30, Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=32.4110671936759, Blast_Score=121, Evalue=5e-29, Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=31.6, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI1787905, Length=248, Percent_Identity=31.4516129032258, Blast_Score=104, Evalue=6e-24, Organism=Escherichia coli, GI87082160, Length=246, Percent_Identity=27.2357723577236, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=30.1587301587302, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=28.6852589641434, Blast_Score=84, Evalue=9e-18, Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=6e-17, Organism=Escherichia coli, GI1786812, Length=252, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI2367365, Length=250, Percent_Identity=29.6, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1787526, Length=252, Percent_Identity=26.1904761904762, Blast_Score=62, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=30.3149606299213, Blast_Score=128, Evalue=2e-30, Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=30.5882352941176, Blast_Score=123, Evalue=1e-28, Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=34.412955465587, Blast_Score=121, Evalue=4e-28, Organism=Caenorhabditis elegans, GI25147288, Length=254, Percent_Identity=33.0708661417323, Blast_Score=120, Evalue=7e-28, Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=28.8461538461538, Blast_Score=107, Evalue=8e-24, Organism=Caenorhabditis elegans, GI17538182, Length=259, Percent_Identity=30.1158301158301, Blast_Score=103, Evalue=6e-23, Organism=Caenorhabditis elegans, GI17544670, Length=272, Percent_Identity=28.3088235294118, Blast_Score=103, Evalue=7e-23, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=28.8973384030418, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI17551412, Length=271, Percent_Identity=29.1512915129151, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=30.9433962264151, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=31.1023622047244, Blast_Score=97, Evalue=9e-21, Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=27.0992366412214, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=28.4090909090909, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=28.9473684210526, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17531453, Length=262, Percent_Identity=26.3358778625954, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17562910, Length=268, Percent_Identity=26.1194029850746, Blast_Score=94, Evalue=9e-20, Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=29.296875, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI193204405, Length=267, Percent_Identity=26.5917602996255, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17563726, Length=269, Percent_Identity=25.2788104089219, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17562904, Length=267, Percent_Identity=26.9662921348315, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17568967, Length=242, Percent_Identity=30.5785123966942, Blast_Score=88, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=26.4150943396226, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17536025, Length=254, Percent_Identity=27.5590551181102, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17565030, Length=266, Percent_Identity=27.4436090225564, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=25.7692307692308, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=23.8461538461538, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17561272, Length=230, Percent_Identity=30.4347826086957, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17538486, Length=271, Percent_Identity=27.6752767527675, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI71982365, Length=197, Percent_Identity=31.9796954314721, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=29.5081967213115, Blast_Score=78, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17555612, Length=216, Percent_Identity=25.462962962963, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17536651, Length=254, Percent_Identity=25.1968503937008, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI193203117, Length=215, Percent_Identity=23.2558139534884, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI193203115, Length=214, Percent_Identity=23.8317757009346, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17508651, Length=252, Percent_Identity=26.1904761904762, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=189, Percent_Identity=35.978835978836, Blast_Score=94, Evalue=2e-20, Organism=Saccharomyces cerevisiae, GI6324126, Length=253, Percent_Identity=26.4822134387352, Blast_Score=76, Evalue=7e-15, Organism=Saccharomyces cerevisiae, GI6320089, Length=192, Percent_Identity=27.0833333333333, Blast_Score=62, Evalue=7e-11, Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=30.3149606299213, Blast_Score=122, Evalue=3e-28, Organism=Drosophila melanogaster, GI24639444, Length=251, Percent_Identity=31.8725099601594, Blast_Score=115, Evalue=3e-26, Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=32.1428571428571, Blast_Score=108, Evalue=4e-24, Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=33.0708661417323, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=31.6205533596838, Blast_Score=105, Evalue=4e-23, Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=30.5220883534137, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI17737361, Length=230, Percent_Identity=31.7391304347826, Blast_Score=100, Evalue=2e-21, Organism=Drosophila melanogaster, GI18859837, Length=192, Percent_Identity=33.8541666666667, Blast_Score=95, Evalue=4e-20, Organism=Drosophila melanogaster, GI24643142, Length=254, Percent_Identity=28.740157480315, Blast_Score=88, Evalue=4e-18, Organism=Drosophila melanogaster, GI24644337, Length=252, Percent_Identity=31.3492063492063, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI281364892, Length=223, Percent_Identity=30.9417040358744, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI281364494, Length=222, Percent_Identity=31.981981981982, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24641232, Length=207, Percent_Identity=29.951690821256, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24665243, Length=202, Percent_Identity=29.7029702970297, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI21357673, Length=223, Percent_Identity=28.2511210762332, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI221331218, Length=202, Percent_Identity=29.7029702970297, Blast_Score=74, Evalue=9e-14, Organism=Drosophila melanogaster, GI24665247, Length=203, Percent_Identity=29.5566502463054, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI221331216, Length=203, Percent_Identity=29.5566502463054, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24663911, Length=208, Percent_Identity=27.4038461538462, Blast_Score=64, Evalue=8e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26836; Mature: 26836
Theoretical pI: Translated: 5.06; Mature: 5.06
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MMDLTQRLAGRVAVITGAGGGIGLAAARRMHAEGATIVVADIDADAGAAAADELSGLFVP CCCHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHCCCEEEE TDVADEDAVNALFDTAARRYGRIDIAFNNAGISPPDDDVIENTEPPAWQRVQDVNLKSVY CCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHH LCCRAALRHMVSARRGSIINTASFVAVMGSATSQISYTAAKGGVLALSRELGVQFARQGI HHHHHHHHHHHHHHCCCEECHHHHHHHHCCCCCCEEEEECCCCEEEEHHHHHHHHHHCCC RVNALCPGPVNTPLLQELFAKDPQRAARRLVHVPVGRFAEPGEIAAAAAFLASDDASFIT EEEEECCCCCCCHHHHHHHCCCHHHHHHHEEECCCCCCCCCCHHHHHHHHHHCCCCCEEE ASTFLVDGGISAAYVTPL EEEEEEECCCCEEEECCC >Mature Secondary Structure MMDLTQRLAGRVAVITGAGGGIGLAAARRMHAEGATIVVADIDADAGAAAADELSGLFVP CCCHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHCCCEEEE TDVADEDAVNALFDTAARRYGRIDIAFNNAGISPPDDDVIENTEPPAWQRVQDVNLKSVY CCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHH LCCRAALRHMVSARRGSIINTASFVAVMGSATSQISYTAAKGGVLALSRELGVQFARQGI HHHHHHHHHHHHHHCCCEECHHHHHHHHCCCCCCEEEEECCCCEEEEHHHHHHHHHHCCC RVNALCPGPVNTPLLQELFAKDPQRAARRLVHVPVGRFAEPGEIAAAAAFLASDDASFIT EEEEECCCCCCCHHHHHHHCCCHHHHHHHEEECCCCCCCCCCHHHHHHHHHHCCCCCEEE ASTFLVDGGISAAYVTPL EEEEEEECCCCEEEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]