Click here to switch to the map view.

The map label for this gene is ribF

Identifier: 41408991

GI number: 41408991

Start: 3223875

End: 3224858

Strand: Reverse

Name: ribF

Synonym: MAP2893c

Alternate gene names: 41408991

Gene position: 3224858-3223875 (Counterclockwise)

Preceding gene: 41408994

Following gene: 41408990

Centisome position: 66.77

GC content: 69.51

Gene sequence:

>984_bases
CTGGCGGGCGTGCAGCGGTGGCGCGGCCAAGACGAGATACCCACGGACTGGGGCAGGTGTGTGCTGACCATCGGCGTGTT
CGACGGTGTGCACCGCGGCCATGCCGAGCTGATCGCGCACGCGGTCAAGGCGGGGCGGGCTCGCAACGTGCCGACGGTGT
TGATGACGTTCGACCCGCACCCGATGGAAGTGGTCTACCCGGGCAGCCATCCCGCCCAGTTGACGACGCTGACCCGGCGC
GCCGAGCTGGTCGAGGAGCTGGGCATCGACGTTTTCCTGGTGATGCCGTTCACCACCGACTTCATGAAACTCACCCCGGA
CCGCTACGTGCACGAGCTGCTGGTGGAGAACCTGCACGTGGTCGAGGTGGTGGTGGGGGAGAACTTCACCTTCGGCAAGA
AGGCGACCGGCAATGTGGAGACGCTGCGGCGGGCCGGCGAGCGGTTCGGGTTCGCCGTGGAGGCGATGTCGCTGCTGTCC
GAGCACCACAGCAACCAGACCGTGACGTTCTCCTCGACCTACATCCGGTCCTGCGTGGACGCCGGCGACGTGGTGGCGGC
CATGGAGGCGCTGGGCCGTCCGCACCGGGTGGAGGGCGTCGTCGTCCGCGGCGAGGGGCGGGGGATCCAACTGGGCTTCC
CGACCGCCAACGTGGCCCCGCCGATGTATTCGGCGATCCCCGCCGACGGGGTCTACGCCGCCTGGTTCACCGTGCTGGGC
CACGGGCCGGTGACCGGCACCGTCATCCCGGGTGAGCGCTACCAGGCGGCGGTATCGGTGGGCACCAACCCGACCTTTTC
CGGGCGCACCCGCACCGTCGAGGCGTTCGTCCTGGACACCCAGGCCGACCTGTACGGGCAGCACGTCGCGCTGGATTTCG
TCGCCCGCATCCGCGGCCAGCACAAGTTCGACTCGGTCGACGACCTCGTCGTCGCGATGGGCCAGGACACCGAGCGGGCG
CGTCAGCTGCTGTCCGCGGGCTGA

Upstream 100 bases:

>100_bases
AGAAAGTTTAGGCAACCCAACCTCGATCCGGCGTGTTCCCCGCCACCTCGCCCGGCGTTGCGCGCCGCGGACCTCCCGGC
GGGCGGCCGCGCGCCGTAGG

Downstream 100 bases:

>100_bases
GGTTCGCAGACCAGCGTTTATGCCCGCCGGTCCCGGCGCTGCTAGACTGCCCGACGACATCGGCGCGTGCTGCGGTTCGC
GGTGGCCGCGCCCGAACTCG

Product: bifunctional riboflavin kinase/FMN adenylyltransferase

Products: NA

Alternate protein names: Riboflavin kinase; Flavokinase; FMN adenylyltransferase; FAD pyrophosphorylase; FAD synthase [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MAGVQRWRGQDEIPTDWGRCVLTIGVFDGVHRGHAELIAHAVKAGRARNVPTVLMTFDPHPMEVVYPGSHPAQLTTLTRR
AELVEELGIDVFLVMPFTTDFMKLTPDRYVHELLVENLHVVEVVVGENFTFGKKATGNVETLRRAGERFGFAVEAMSLLS
EHHSNQTVTFSSTYIRSCVDAGDVVAAMEALGRPHRVEGVVVRGEGRGIQLGFPTANVAPPMYSAIPADGVYAAWFTVLG
HGPVTGTVIPGERYQAAVSVGTNPTFSGRTRTVEAFVLDTQADLYGQHVALDFVARIRGQHKFDSVDDLVVAMGQDTERA
RQLLSAG

Sequences:

>Translated_327_residues
MAGVQRWRGQDEIPTDWGRCVLTIGVFDGVHRGHAELIAHAVKAGRARNVPTVLMTFDPHPMEVVYPGSHPAQLTTLTRR
AELVEELGIDVFLVMPFTTDFMKLTPDRYVHELLVENLHVVEVVVGENFTFGKKATGNVETLRRAGERFGFAVEAMSLLS
EHHSNQTVTFSSTYIRSCVDAGDVVAAMEALGRPHRVEGVVVRGEGRGIQLGFPTANVAPPMYSAIPADGVYAAWFTVLG
HGPVTGTVIPGERYQAAVSVGTNPTFSGRTRTVEAFVLDTQADLYGQHVALDFVARIRGQHKFDSVDDLVVAMGQDTERA
RQLLSAG
>Mature_326_residues
AGVQRWRGQDEIPTDWGRCVLTIGVFDGVHRGHAELIAHAVKAGRARNVPTVLMTFDPHPMEVVYPGSHPAQLTTLTRRA
ELVEELGIDVFLVMPFTTDFMKLTPDRYVHELLVENLHVVEVVVGENFTFGKKATGNVETLRRAGERFGFAVEAMSLLSE
HHSNQTVTFSSTYIRSCVDAGDVVAAMEALGRPHRVEGVVVRGEGRGIQLGFPTANVAPPMYSAIPADGVYAAWFTVLGH
GPVTGTVIPGERYQAAVSVGTNPTFSGRTRTVEAFVLDTQADLYGQHVALDFVARIRGQHKFDSVDDLVVAMGQDTERAR
QLLSAG

Specific function: Unknown

COG id: COG0196

COG function: function code H; FAD synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribF family [H]

Homologues:

Organism=Homo sapiens, GI269973877, Length=136, Percent_Identity=33.0882352941176, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1786208, Length=305, Percent_Identity=35.4098360655738, Blast_Score=189, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17541882, Length=132, Percent_Identity=32.5757575757576, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24644927, Length=131, Percent_Identity=34.3511450381679, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015864
- InterPro:   IPR015865
- InterPro:   IPR002606
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06574 FAD_syn; PF01687 Flavokinase [H]

EC number: =2.7.1.26; =2.7.7.2 [H]

Molecular weight: Translated: 35634; Mature: 35503

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGVQRWRGQDEIPTDWGRCVLTIGVFDGVHRGHAELIAHAVKAGRARNVPTVLMTFDPH
CCCCCHHCCCCCCCCCCCCEEEEEEHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCC
PMEVVYPGSHPAQLTTLTRRAELVEELGIDVFLVMPFTTDFMKLTPDRYVHELLVENLHV
CCEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHCCHHHHHHHHHHCCCEE
VEVVVGENFTFGKKATGNVETLRRAGERFGFAVEAMSLLSEHHSNQTVTFSSTYIRSCVD
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHC
AGDVVAAMEALGRPHRVEGVVVRGEGRGIQLGFPTANVAPPMYSAIPADGVYAAWFTVLG
HHHHHHHHHHCCCCCEEEEEEEECCCCEEEEECCCCCCCCCHHHCCCCCCHHHHHHHHHC
HGPVTGTVIPGERYQAAVSVGTNPTFSGRTRTVEAFVLDTQADLYGQHVALDFVARIRGQ
CCCCEEEEECCCCEEEEEEECCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHCCC
HKFDSVDDLVVAMGQDTERARQLLSAG
CCCCCHHHHHEECCCCHHHHHHHHHCC
>Mature Secondary Structure 
AGVQRWRGQDEIPTDWGRCVLTIGVFDGVHRGHAELIAHAVKAGRARNVPTVLMTFDPH
CCCCHHCCCCCCCCCCCCEEEEEEHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCC
PMEVVYPGSHPAQLTTLTRRAELVEELGIDVFLVMPFTTDFMKLTPDRYVHELLVENLHV
CCEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHCCHHHHHHHHHHCCCEE
VEVVVGENFTFGKKATGNVETLRRAGERFGFAVEAMSLLSEHHSNQTVTFSSTYIRSCVD
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHC
AGDVVAAMEALGRPHRVEGVVVRGEGRGIQLGFPTANVAPPMYSAIPADGVYAAWFTVLG
HHHHHHHHHHCCCCCEEEEEEEECCCCEEEEECCCCCCCCCHHHCCCCCCHHHHHHHHHC
HGPVTGTVIPGERYQAAVSVGTNPTFSGRTRTVEAFVLDTQADLYGQHVALDFVARIRGQ
CCCCEEEEECCCCEEEEEEECCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHCCC
HKFDSVDDLVVAMGQDTERARQLLSAG
CCCCCHHHHHEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7772835; 3023344 [H]