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The map label for this gene is ophA1 [H]

Identifier: 41408982

GI number: 41408982

Start: 3212675

End: 3213775

Strand: Reverse

Name: ophA1 [H]

Synonym: MAP2884c

Alternate gene names: 41408982

Gene position: 3213775-3212675 (Counterclockwise)

Preceding gene: 41408983

Following gene: 41408980

Centisome position: 66.54

GC content: 71.84

Gene sequence:

>1101_bases
ATGAGCATCCGCTGGGCCGCGTCGCGCCCGCCGAGCATCTGGGCCAGCAGACCCGCCGACCTGTACGGCCGGCGCGACCA
CGATCGCTTCACCGCGGTGCTGTGGGGCGTGCGGGCGGTGTTCGAGGGCTTCGCCTCGGTGTCGCGGTGGCACCCGGCGC
GGGTGAAACCCGTGCAGCGCAAGCTGACCGCGGTGGTGACCAAACGCGAGTTCGCCGCCCCCGACGTCGTCGCGTTGACC
CTGGCCGACCCCGACGGCGGGTTGCTGCCGTCCTGGACACCGGGCGCGCACATCGACGTGCTGTTGCCCTCGGGCCGGCG
CCGGCAGTACTCGCTGTGTGGCCCGCCCGGGCACCGCGGCGAGTACCGCATCGCGGTGCGCCGCATCGCCGACGGCGGCG
GCGGATCGATCGAGATGCACGAGGCGTTCGGCGTGGGCGACACCGTGGAGTTCGAGGGCCCACGCAACGCGTTCTACCTG
GGCACCGCCGAACACGACGTGTTGTTCGTCATCGGCGGCATCGGGGTGACGCCCATCCTGCCGATGATCCGGGTGGCCGC
GCAGCGCGGAATCGATTGGCGCGCAATCTATACCGGCCGCAGCCGCGAGTACATGCCGCTACTCGACGAGGTGGTTTCGG
TGGACCCGCAGCGGGTGACGGTGTGGGCCGACGACGAGCACGGCCGGTTTCCCACCGCGGCGGAGCTGCTGGCGGCGGCC
GGCCCGGCGACGGCCGTCTACGTGTGCGGCCCGAGCGCCATGCTCGAGGCCGTCCGGATCGCCCGGAACGAACATGCCGG
CGCGCCACTGCATTACGAGCGGTTCAGCCCGGCGCCGGTCGTCGACGGTGTCCCGTTCGAGCTGGAGTTGGCGCGATCAC
GGCAGGTGCTCGCCGTGCCGGCGAACCGGACGGCGCTGGACGTCATGCTCGACCGCGACCCGACGACACCGTATTCGTGC
CGGCAAGGATTCTGCGGCACCTGCCGGGTGAAAGTGCTTGCCGGACAGGTGGATCACCGTGGCCGCACCGATCCGGGCCA
GGACGGCATGCTGGTCTGCGTCTCGCGGGCCGACGGCGGGCGGCTGGTCATCGACGCCTGA

Upstream 100 bases:

>100_bases
CGGTGGTGCCGATCGCCGCCGAGTCGCGGATCGGCTACGCGCTGCGCCGGATCAGCCCCGGCGCGATCCGGCTGTTGGCG
CGCTGGGACATTCGACAGAC

Downstream 100 bases:

>100_bases
GTGCGTCGTCACGGTCGGGACTGCTCCAGGTAGGCGGCCAGGGCGTTGGTCAGGCCCCGGCGCGCCATGTCGAGGTCGGC
GTAGGAGCCCAGCTGGCGTT

Product: hypothetical protein

Products: NA

Alternate protein names: PDR [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSIRWAASRPPSIWASRPADLYGRRDHDRFTAVLWGVRAVFEGFASVSRWHPARVKPVQRKLTAVVTKREFAAPDVVALT
LADPDGGLLPSWTPGAHIDVLLPSGRRRQYSLCGPPGHRGEYRIAVRRIADGGGGSIEMHEAFGVGDTVEFEGPRNAFYL
GTAEHDVLFVIGGIGVTPILPMIRVAAQRGIDWRAIYTGRSREYMPLLDEVVSVDPQRVTVWADDEHGRFPTAAELLAAA
GPATAVYVCGPSAMLEAVRIARNEHAGAPLHYERFSPAPVVDGVPFELELARSRQVLAVPANRTALDVMLDRDPTTPYSC
RQGFCGTCRVKVLAGQVDHRGRTDPGQDGMLVCVSRADGGRLVIDA

Sequences:

>Translated_366_residues
MSIRWAASRPPSIWASRPADLYGRRDHDRFTAVLWGVRAVFEGFASVSRWHPARVKPVQRKLTAVVTKREFAAPDVVALT
LADPDGGLLPSWTPGAHIDVLLPSGRRRQYSLCGPPGHRGEYRIAVRRIADGGGGSIEMHEAFGVGDTVEFEGPRNAFYL
GTAEHDVLFVIGGIGVTPILPMIRVAAQRGIDWRAIYTGRSREYMPLLDEVVSVDPQRVTVWADDEHGRFPTAAELLAAA
GPATAVYVCGPSAMLEAVRIARNEHAGAPLHYERFSPAPVVDGVPFELELARSRQVLAVPANRTALDVMLDRDPTTPYSC
RQGFCGTCRVKVLAGQVDHRGRTDPGQDGMLVCVSRADGGRLVIDA
>Mature_365_residues
SIRWAASRPPSIWASRPADLYGRRDHDRFTAVLWGVRAVFEGFASVSRWHPARVKPVQRKLTAVVTKREFAAPDVVALTL
ADPDGGLLPSWTPGAHIDVLLPSGRRRQYSLCGPPGHRGEYRIAVRRIADGGGGSIEMHEAFGVGDTVEFEGPRNAFYLG
TAEHDVLFVIGGIGVTPILPMIRVAAQRGIDWRAIYTGRSREYMPLLDEVVSVDPQRVTVWADDEHGRFPTAAELLAAAG
PATAVYVCGPSAMLEAVRIARNEHAGAPLHYERFSPAPVVDGVPFELELARSRQVLAVPANRTALDVMLDRDPTTPYSCR
QGFCGTCRVKVLAGQVDHRGRTDPGQDGMLVCVSRADGGRLVIDA

Specific function: Component of the electron transfer chain involved in pyridine nucleotide-dependent dihydroxylation of phthalate. Utilizes FMN to mediate electron transfer from the two-electron donor, NADH, to the one-electron acceptor, (2Fe-2S) [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788104, Length=312, Percent_Identity=36.8589743589744, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1788903, Length=234, Percent_Identity=28.2051282051282, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39829; Mature: 39698

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRWAASRPPSIWASRPADLYGRRDHDRFTAVLWGVRAVFEGFASVSRWHPARVKPVQR
CCEEECCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
KLTAVVTKREFAAPDVVALTLADPDGGLLPSWTPGAHIDVLLPSGRRRQYSLCGPPGHRG
HHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCCC
EYRIAVRRIADGGGGSIEMHEAFGVGDTVEFEGPRNAFYLGTAEHDVLFVIGGIGVTPIL
CEEEEEEEEECCCCCEEEEEHHCCCCCEEEECCCCCEEEEECCCCCEEEEECCCCHHHHH
PMIRVAAQRGIDWRAIYTGRSREYMPLLDEVVSVDPQRVTVWADDEHGRFPTAAELLAAA
HHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHC
GPATAVYVCGPSAMLEAVRIARNEHAGAPLHYERFSPAPVVDGVPFELELARSRQVLAVP
CCCEEEEEECCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCEEEECCCCEEEEEC
ANRTALDVMLDRDPTTPYSCRQGFCGTCRVKVLAGQVDHRGRTDPGQDGMLVCVSRADGG
CCCEEEEEEEECCCCCCHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEEEECCCC
RLVIDA
EEEEEC
>Mature Secondary Structure 
SIRWAASRPPSIWASRPADLYGRRDHDRFTAVLWGVRAVFEGFASVSRWHPARVKPVQR
CEEECCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
KLTAVVTKREFAAPDVVALTLADPDGGLLPSWTPGAHIDVLLPSGRRRQYSLCGPPGHRG
HHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCCC
EYRIAVRRIADGGGGSIEMHEAFGVGDTVEFEGPRNAFYLGTAEHDVLFVIGGIGVTPIL
CEEEEEEEEECCCCCEEEEEHHCCCCCEEEECCCCCEEEEECCCCCEEEEECCCCHHHHH
PMIRVAAQRGIDWRAIYTGRSREYMPLLDEVVSVDPQRVTVWADDEHGRFPTAAELLAAA
HHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHC
GPATAVYVCGPSAMLEAVRIARNEHAGAPLHYERFSPAPVVDGVPFELELARSRQVLAVP
CCCEEEEEECCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCEEEECCCCEEEEEC
ANRTALDVMLDRDPTTPYSCRQGFCGTCRVKVLAGQVDHRGRTDPGQDGMLVCVSRADGG
CCCEEEEEEEECCCCCCHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEEEECCCC
RLVIDA
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FMN. [C]

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9851995; 1280857 [H]