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The map label for this gene is kshA [H]

Identifier: 41408980

GI number: 41408980

Start: 3210899

End: 3211960

Strand: Reverse

Name: kshA [H]

Synonym: MAP2882c

Alternate gene names: 41408980

Gene position: 3211960-3210899 (Counterclockwise)

Preceding gene: 41408982

Following gene: 41408979

Centisome position: 66.5

GC content: 65.35

Gene sequence:

>1062_bases
TTGATTTGGCGGCGGGGCGGCCTAATATTCGTACCCGAGGGAGGGCAGCTCAGATGGGAGGGCACGATGGCTAAGCCGCC
GTTGTCGATGAAGCCGACCGGCTGGTTCCAGGTCGCCTGGTCCGACGAGATCGGCGTCGGCGACGTGCACAAGATGAAGT
ACTTCGACCAGGAGATGGTCGCCTGGCGCGCCGAATCCGGTCAGCTCACGGTGATGAACGCCTACTGCGAACACCTGGGC
GCGCACCTGGGCTACGGCGGCAAGGTCGTCGGCGAGGTGCTGCAGTGCCCGTTCCACGGGTGGCAGTGGAGCGCCGAGGG
CCGCAACGTGTGCATCCCGTACCAGGATCGGCCCAACCGCGGCCGGCGGATGCGCACCTATCCGGTGGTGGAACGCAACG
CCTCCGTGTACATCTGGCATGACCTACAGCGTCGCGAGCCCTACTTCGACCCGCCCGACGTGTTCGCCGCCTTCGGCGAC
GGCAGCAGCGCCGACGACTACTACCCGCAGCAGCGGCTGTACCGGCAGGCGCTGGAGATGCATCCGCAGTACGTACTGGA
GAACGGGGTGGACTTCGCGCACTTCAAATTCGTGCACAACACCCCGATCGTGCCGGTGTTCACCCGGCACGACTTCGCCG
AGCCGGTGTCCTACGTCGACTTCACCATCACGTTCGAGGGCGACGACGGCCAAAAGATCGAGGACGTCAACAGCGGTGTG
CAGGCCATCAACGGCGGGCTCGGGATCGCGGTGACCAAGAGCTGGGGCATGATCGACAACCGCACCATCTCGGCGATCAC
CCCGGTCGACGAGCGCACCTCCGACGTCCGGTTCATGGTCTACATCGGGCGGACGCCGGCCAAGGATGCGGCCCGCGCAC
AGCGCAAGGCGGCCGAATTCGGGGACGAGGTGATCCGGCAGTTCACCCAGGACATCGAAATCTGGCAGCACCAGCGGTAT
TCGGATCCGCCGGCGCTGGCCGCCGACGAGTATCAGGGCTTCATGGCAATTCGCCAGTGGGCCAAGCAGTTCTATCCCGA
GTTCGCAGCGCAGGAGGCTTAG

Upstream 100 bases:

>100_bases
GGGGCGCCGGCCGGCGACCCCGGCCCCGCTGGTCTGCCGGGTCATTCGTCGATCTTATCCGCCGGCACTTATCCGCCCGC
AGAGTTTCATAGAGGGTACT

Downstream 100 bases:

>100_bases
GCAAATGGGCACAGCACCGATTCGCGTCTTCCAGGTCGGAAGCGGCAACGTCGGCTCCGAGATGATCAGGCGGATCGCGA
CCCAGCCGGATCTGGAACTG

Product: hypothetical protein

Products: NA

Alternate protein names: Rieske-type oxygenase; RO [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MIWRRGGLIFVPEGGQLRWEGTMAKPPLSMKPTGWFQVAWSDEIGVGDVHKMKYFDQEMVAWRAESGQLTVMNAYCEHLG
AHLGYGGKVVGEVLQCPFHGWQWSAEGRNVCIPYQDRPNRGRRMRTYPVVERNASVYIWHDLQRREPYFDPPDVFAAFGD
GSSADDYYPQQRLYRQALEMHPQYVLENGVDFAHFKFVHNTPIVPVFTRHDFAEPVSYVDFTITFEGDDGQKIEDVNSGV
QAINGGLGIAVTKSWGMIDNRTISAITPVDERTSDVRFMVYIGRTPAKDAARAQRKAAEFGDEVIRQFTQDIEIWQHQRY
SDPPALAADEYQGFMAIRQWAKQFYPEFAAQEA

Sequences:

>Translated_353_residues
MIWRRGGLIFVPEGGQLRWEGTMAKPPLSMKPTGWFQVAWSDEIGVGDVHKMKYFDQEMVAWRAESGQLTVMNAYCEHLG
AHLGYGGKVVGEVLQCPFHGWQWSAEGRNVCIPYQDRPNRGRRMRTYPVVERNASVYIWHDLQRREPYFDPPDVFAAFGD
GSSADDYYPQQRLYRQALEMHPQYVLENGVDFAHFKFVHNTPIVPVFTRHDFAEPVSYVDFTITFEGDDGQKIEDVNSGV
QAINGGLGIAVTKSWGMIDNRTISAITPVDERTSDVRFMVYIGRTPAKDAARAQRKAAEFGDEVIRQFTQDIEIWQHQRY
SDPPALAADEYQGFMAIRQWAKQFYPEFAAQEA
>Mature_353_residues
MIWRRGGLIFVPEGGQLRWEGTMAKPPLSMKPTGWFQVAWSDEIGVGDVHKMKYFDQEMVAWRAESGQLTVMNAYCEHLG
AHLGYGGKVVGEVLQCPFHGWQWSAEGRNVCIPYQDRPNRGRRMRTYPVVERNASVYIWHDLQRREPYFDPPDVFAAFGD
GSSADDYYPQQRLYRQALEMHPQYVLENGVDFAHFKFVHNTPIVPVFTRHDFAEPVSYVDFTITFEGDDGQKIEDVNSGV
QAINGGLGIAVTKSWGMIDNRTISAITPVDERTSDVRFMVYIGRTPAKDAARAQRKAAEFGDEVIRQFTQDIEIWQHQRY
SDPPALAADEYQGFMAIRQWAKQFYPEFAAQEA

Specific function: Catalyzes the opening of ring B of 1,4-androstadiene- 3,17,-dione (ADD) and 4-androstene-3,17-dione (ADD) with concomitant aromatization of ring A. The ring B is subsequently hydroxylated to yield a catechol and then subject to meta- cleavage [H]

COG id: COG4638

COG function: function code PR; Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Rieske domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI71983709, Length=364, Percent_Identity=26.3736263736264, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI161085896, Length=353, Percent_Identity=24.929178470255, Blast_Score=105, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017941 [H]

Pfam domain/function: PF00355 Rieske [H]

EC number: NA

Molecular weight: Translated: 40422; Mature: 40422

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIWRRGGLIFVPEGGQLRWEGTMAKPPLSMKPTGWFQVAWSDEIGVGDVHKMKYFDQEMV
CEEECCCEEEEECCCEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
AWRAESGQLTVMNAYCEHLGAHLGYGGKVVGEVLQCPFHGWQWSAEGRNVCIPYQDRPNR
HEECCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEECCCCCEEEECCCCCCCC
GRRMRTYPVVERNASVYIWHDLQRREPYFDPPDVFAAFGDGSSADDYYPQQRLYRQALEM
CCEEEECCEEECCCCEEEEECHHHCCCCCCCHHHEEEECCCCCCCCCCHHHHHHHHHHHH
HPQYVLENGVDFAHFKFVHNTPIVPVFTRHDFAEPVSYVDFTITFEGDDGQKIEDVNSGV
CHHHHHHCCCCEEEEEEEECCCCEEEECCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHH
QAINGGLGIAVTKSWGMIDNRTISAITPVDERTSDVRFMVYIGRTPAKDAARAQRKAAEF
HHHCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHH
GDEVIRQFTQDIEIWQHQRYSDPPALAADEYQGFMAIRQWAKQFYPEFAAQEA
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHCCCC
>Mature Secondary Structure
MIWRRGGLIFVPEGGQLRWEGTMAKPPLSMKPTGWFQVAWSDEIGVGDVHKMKYFDQEMV
CEEECCCEEEEECCCEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
AWRAESGQLTVMNAYCEHLGAHLGYGGKVVGEVLQCPFHGWQWSAEGRNVCIPYQDRPNR
HEECCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEECCCCCEEEECCCCCCCC
GRRMRTYPVVERNASVYIWHDLQRREPYFDPPDVFAAFGDGSSADDYYPQQRLYRQALEM
CCEEEECCEEECCCCEEEEECHHHCCCCCCCHHHEEEECCCCCCCCCCHHHHHHHHHHHH
HPQYVLENGVDFAHFKFVHNTPIVPVFTRHDFAEPVSYVDFTITFEGDDGQKIEDVNSGV
CHHHHHHCCCCEEEEEEEECCCCEEEECCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHH
QAINGGLGIAVTKSWGMIDNRTISAITPVDERTSDVRFMVYIGRTPAKDAARAQRKAAEF
HHHCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHH
GDEVIRQFTQDIEIWQHQRYSDPPALAADEYQGFMAIRQWAKQFYPEFAAQEA
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]