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The map label for this gene is trkB

Identifier: 41408907

GI number: 41408907

Start: 3141091

End: 3141747

Strand: Direct

Name: trkB

Synonym: MAP2809

Alternate gene names: 41408907

Gene position: 3141091-3141747 (Clockwise)

Preceding gene: 41408906

Following gene: 41408910

Centisome position: 65.04

GC content: 70.02

Gene sequence:

>657_bases
ATGAAGGTAGCTGTCGCCGGCGCCGGCGCGGTCGGCCGCTCGGTCACCCGGGAACTTCTGGCCAATGGGCACGACGTGAC
CCTGATCGAACGCAACCCCGATCACGTCGACGTCGACGCCATCCCGGCCGCGCACTGGCGGCTGGGCGACGCCTGCGAGC
TGAGCCTGCTGGAGTCGGTGCAGCTGCAGGAGTTCGACGTGGTGGTGGCCGCCACCGGCGACGACAAGGCCAACGTGGTG
CTGAGCCTGCTGGCCAAAACCGAGTTCGCGGTGCCGCGGGTGGTGGCCCGGGTCAACGATCCTCGCAACGAATGGCTGTT
CACCGACGCCTGGGGGGTGGACGTGGCGGTGTCGACGCCGCGCATGCTGGCCTCGCTCATCGAGGAGGCCGTCGCCGTCG
GTGATCTGGTGCGGTTGATGGAATTCCGCAAGGGGCAGGCGAACCTGGTCGAGATCACGCTGCCCGACGACACCCCGTGG
GGCGGCAAGCCGGTGCGCCGGCTGCAGCTGCCCCGCGACGCCGCGCTGGTGACCATCCTGCGCGGGCCGCGCGTGATCGT
GCCCGAGGAGGACGAGCCGCTGGAAGGCGGCGACGAGCTGCTGTTCGTCGCCGTGGCCGAGGCCGAAGAGGAACTGCAGA
AACTGCTGCTCGGCTAG

Upstream 100 bases:

>100_bases
CGAAGACCTGTGAACCACGAGGAGCGGCGCACATGAAGACCGCCGACGACGAAGGAGCCGGCTTGCCCCATGGGCAAGCC
GGGTACGAGGAGCGGCGCAA

Downstream 100 bases:

>100_bases
CGGCCGCCGGATTACTCGCCGGCGGCGCCGGAGGCCAGCTCGACCGCGGCGATGGCCCGCTGCGCCGACTTGATCGCGGC
GTAGGTGGGCAGCGCGGCCA

Product: TrkB

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MKVAVAGAGAVGRSVTRELLANGHDVTLIERNPDHVDVDAIPAAHWRLGDACELSLLESVQLQEFDVVVAATGDDKANVV
LSLLAKTEFAVPRVVARVNDPRNEWLFTDAWGVDVAVSTPRMLASLIEEAVAVGDLVRLMEFRKGQANLVEITLPDDTPW
GGKPVRRLQLPRDAALVTILRGPRVIVPEEDEPLEGGDELLFVAVAEAEEELQKLLLG

Sequences:

>Translated_218_residues
MKVAVAGAGAVGRSVTRELLANGHDVTLIERNPDHVDVDAIPAAHWRLGDACELSLLESVQLQEFDVVVAATGDDKANVV
LSLLAKTEFAVPRVVARVNDPRNEWLFTDAWGVDVAVSTPRMLASLIEEAVAVGDLVRLMEFRKGQANLVEITLPDDTPW
GGKPVRRLQLPRDAALVTILRGPRVIVPEEDEPLEGGDELLFVAVAEAEEELQKLLLG
>Mature_218_residues
MKVAVAGAGAVGRSVTRELLANGHDVTLIERNPDHVDVDAIPAAHWRLGDACELSLLESVQLQEFDVVVAATGDDKANVV
LSLLAKTEFAVPRVVARVNDPRNEWLFTDAWGVDVAVSTPRMLASLIEEAVAVGDLVRLMEFRKGQANLVEITLPDDTPW
GGKPVRRLQLPRDAALVTILRGPRVIVPEEDEPLEGGDELLFVAVAEAEEELQKLLLG

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=234, Percent_Identity=23.5042735042735, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 23619; Mature: 23619

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAVAGAGAVGRSVTRELLANGHDVTLIERNPDHVDVDAIPAAHWRLGDACELSLLESV
CEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCEECCCCCCCCCCCCCCHHHHHHHHHC
QLQEFDVVVAATGDDKANVVLSLLAKTEFAVPRVVARVNDPRNEWLFTDAWGVDVAVSTP
CEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCH
RMLASLIEEAVAVGDLVRLMEFRKGQANLVEITLPDDTPWGGKPVRRLQLPRDAALVTIL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHEECCCCCCEEEEEE
RGPRVIVPEEDEPLEGGDELLFVAVAEAEEELQKLLLG
CCCEEEECCCCCCCCCCCEEEEEEEHHHHHHHHHHHCC
>Mature Secondary Structure
MKVAVAGAGAVGRSVTRELLANGHDVTLIERNPDHVDVDAIPAAHWRLGDACELSLLESV
CEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCEECCCCCCCCCCCCCCHHHHHHHHHC
QLQEFDVVVAATGDDKANVVLSLLAKTEFAVPRVVARVNDPRNEWLFTDAWGVDVAVSTP
CEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCH
RMLASLIEEAVAVGDLVRLMEFRKGQANLVEITLPDDTPWGGKPVRRLQLPRDAALVTIL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHEECCCCCCEEEEEE
RGPRVIVPEEDEPLEGGDELLFVAVAEAEEELQKLLLG
CCCEEEECCCCCCCCCCCEEEEEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 9784509 [H]