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The map label for this gene is echA8 [H]

Identifier: 41408846

GI number: 41408846

Start: 3079539

End: 3080420

Strand: Reverse

Name: echA8 [H]

Synonym: MAP2748c

Alternate gene names: 41408846

Gene position: 3080420-3079539 (Counterclockwise)

Preceding gene: 41408847

Following gene: 41408843

Centisome position: 63.78

GC content: 70.52

Gene sequence:

>882_bases
TTGCGGCGCGACGCATCCGCGGCGGCGCCGACCCGAAAGGAGCCCCGTGGCGCAGAACCCCACACCGCCCGACCCCCCCG
TCCGCCCGAAGGCGATTGGCTGGGCACGCCGTACCTGCGCTTCGAGCGCTACGGACCCATCGCGCTGTGCACCATCGACC
GGCCCCAGGCGCGCAATGCGCTGAGCCCGGCGATGTACTTCGGAATCCGTTACGCCGTCGGACGTCTCAACGAGGACCCC
GATCTGGCCGGGCTGGTGCTCACCGGAACCGGCGACGTCTTCGCCCCCGGTGGCGACATGGGCGGCGGGGGCGGCGCGGA
CAACTGGATCACCTTCGGCTCCGCGCTGGGCATGGACGTCACCCCGTTCGACGCGGTGCGCACCTCGGCCAAGCCGATCG
TCTCCGCGGTCAACGGGCTGTGCCAGGGCGGCGGATTCCAGATCGCGCTGTGCAGCGACCTGTCGGTGGTCAGCGATCGC
GCGACCTTCCGGGTGCCCGAGTTGTTCCGCGGCTACGCCGACACCTACTACAGCCAGATGCTGGCCCGGGTCATCGGGCC
GGTGCGCACCCGCGACCTGATGTTCACCGGCCGGGTGCTCACCGCCGTCGAAGCGCTCGACTGGGGCCTGGTCACCCGGG
TGGTGCCGCACGAGAACCTGCTGGACGCGGCCAAAGACCTACTGGCGCAATGCTGCCGGACCGCGCCGCGCGCCCGCGGC
GTCATCAAGTCCAGCCTGGACAACTACCTGGGCCTGTACGACCGCATCGGCATGACCGCCAGCCTGTCCGACGACGAGGC
CATCGAGGGCTTCCGCGCGTTCAAACAACGCCGCTCACCCGACTGGGTGCACCCGGATCTGCGGGTCGACGGACGGTTGT
AG

Upstream 100 bases:

>100_bases
CGAGGTGGTCGCCGACGCTGCCGCCACCGCCGCGACGGCCGCCCTGCCATATGTGTAGCCGCCGGCCCCCGCAGATACTG
TAAGAGCTACCGTAGCGGCG

Downstream 100 bases:

>100_bases
GCCTCAGACCCGCCTGTCCCGGTCGCGCCAAAACGGTTCCCGCAGCTGGGTTTTCAGAATCTTGCCGCTGGCGTTGCGGG
GCAGCTCCGCCACGAAATCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MRRDASAAAPTRKEPRGAEPHTARPPRPPEGDWLGTPYLRFERYGPIALCTIDRPQARNALSPAMYFGIRYAVGRLNEDP
DLAGLVLTGTGDVFAPGGDMGGGGGADNWITFGSALGMDVTPFDAVRTSAKPIVSAVNGLCQGGGFQIALCSDLSVVSDR
ATFRVPELFRGYADTYYSQMLARVIGPVRTRDLMFTGRVLTAVEALDWGLVTRVVPHENLLDAAKDLLAQCCRTAPRARG
VIKSSLDNYLGLYDRIGMTASLSDDEAIEGFRAFKQRRSPDWVHPDLRVDGRL

Sequences:

>Translated_293_residues
MRRDASAAAPTRKEPRGAEPHTARPPRPPEGDWLGTPYLRFERYGPIALCTIDRPQARNALSPAMYFGIRYAVGRLNEDP
DLAGLVLTGTGDVFAPGGDMGGGGGADNWITFGSALGMDVTPFDAVRTSAKPIVSAVNGLCQGGGFQIALCSDLSVVSDR
ATFRVPELFRGYADTYYSQMLARVIGPVRTRDLMFTGRVLTAVEALDWGLVTRVVPHENLLDAAKDLLAQCCRTAPRARG
VIKSSLDNYLGLYDRIGMTASLSDDEAIEGFRAFKQRRSPDWVHPDLRVDGRL
>Mature_293_residues
MRRDASAAAPTRKEPRGAEPHTARPPRPPEGDWLGTPYLRFERYGPIALCTIDRPQARNALSPAMYFGIRYAVGRLNEDP
DLAGLVLTGTGDVFAPGGDMGGGGGADNWITFGSALGMDVTPFDAVRTSAKPIVSAVNGLCQGGGFQIALCSDLSVVSDR
ATFRVPELFRGYADTYYSQMLARVIGPVRTRDLMFTGRVLTAVEALDWGLVTRVVPHENLLDAAKDLLAQCCRTAPRARG
VIKSSLDNYLGLYDRIGMTASLSDDEAIEGFRAFKQRRSPDWVHPDLRVDGRL

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=256, Percent_Identity=24.609375, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI31542718, Length=241, Percent_Identity=24.896265560166, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI70995211, Length=218, Percent_Identity=30.2752293577982, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI260274832, Length=206, Percent_Identity=26.6990291262136, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI45643119, Length=206, Percent_Identity=26.6990291262136, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI260275230, Length=206, Percent_Identity=26.6990291262136, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI68989263, Length=183, Percent_Identity=27.8688524590164, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI221142681, Length=270, Percent_Identity=31.4814814814815, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788597, Length=261, Percent_Identity=31.8007662835249, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787659, Length=258, Percent_Identity=28.6821705426357, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1788682, Length=190, Percent_Identity=29.4736842105263, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082183, Length=265, Percent_Identity=27.5471698113208, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790281, Length=207, Percent_Identity=27.0531400966184, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17554946, Length=255, Percent_Identity=26.6666666666667, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI25145438, Length=245, Percent_Identity=26.9387755102041, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560910, Length=256, Percent_Identity=25.78125, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17536985, Length=238, Percent_Identity=26.4705882352941, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17535521, Length=215, Percent_Identity=23.2558139534884, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17540714, Length=194, Percent_Identity=25.7731958762887, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI20129971, Length=268, Percent_Identity=27.9850746268657, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24653477, Length=268, Percent_Identity=27.9850746268657, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21357171, Length=309, Percent_Identity=27.831715210356, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19920382, Length=221, Percent_Identity=27.1493212669683, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 31833; Mature: 31833

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRDASAAAPTRKEPRGAEPHTARPPRPPEGDWLGTPYLRFERYGPIALCTIDRPQARNA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEECCHHHHHH
LSPAMYFGIRYAVGRLNEDPDLAGLVLTGTGDVFAPGGDMGGGGGADNWITFGSALGMDV
CCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEECCCCCCCCCCCCCCCEEHHHHCCCCC
TPFDAVRTSAKPIVSAVNGLCQGGGFQIALCSDLSVVSDRATFRVPELFRGYADTYYSQM
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCEECHHHHHHHHHHHHHHH
LARVIGPVRTRDLMFTGRVLTAVEALDWGLVTRVVPHENLLDAAKDLLAQCCRTAPRARG
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHH
VIKSSLDNYLGLYDRIGMTASLSDDEAIEGFRAFKQRRSPDWVHPDLRVDGRL
HHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCEECCCC
>Mature Secondary Structure
MRRDASAAAPTRKEPRGAEPHTARPPRPPEGDWLGTPYLRFERYGPIALCTIDRPQARNA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEECCHHHHHH
LSPAMYFGIRYAVGRLNEDPDLAGLVLTGTGDVFAPGGDMGGGGGADNWITFGSALGMDV
CCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEECCCCCCCCCCCCCCCEEHHHHCCCCC
TPFDAVRTSAKPIVSAVNGLCQGGGFQIALCSDLSVVSDRATFRVPELFRGYADTYYSQM
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCEECHHHHHHHHHHHHHHH
LARVIGPVRTRDLMFTGRVLTAVEALDWGLVTRVVPHENLLDAAKDLLAQCCRTAPRARG
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHH
VIKSSLDNYLGLYDRIGMTASLSDDEAIEGFRAFKQRRSPDWVHPDLRVDGRL
HHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]