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The map label for this gene is yjcE [C]

Identifier: 41408815

GI number: 41408815

Start: 3053182

End: 3054939

Strand: Direct

Name: yjcE [C]

Synonym: MAP2717

Alternate gene names: 41408815

Gene position: 3053182-3054939 (Clockwise)

Preceding gene: 41408802

Following gene: 41408819

Centisome position: 63.22

GC content: 72.13

Gene sequence:

>1758_bases
ATGCTATCGGGGCGGCCGAACGGCGAGCAGGGCCGTCGAGTAGCCACCGTCCGGTCCGGCACAATGAGGTCGATGGGCGC
GCAGACGGCTTTGACCTTGCTGCTCGCTGCCATCGCGGTCATCGTGCTGGTCGACTGGATCAGCGAGCGCACCCGCCTGC
CCAGCGCGACGCTGCTGGTCCTGGTCGGCATCGGGCAGGCGCTGCTGCCGGGACCGACCATCGGCCTCGAGCCCGACGTC
GTGATGACCTGCATCCTGCCGCCCCTGCTCTACCACGCGGCGCTGGAATCGTCGCTGGTCGGCATCCGCCGCAATCTACG
CACGGTGGTCAGCCTGTCGGTCGTCCTCGTGCTGCTGACCGCTGCGTCGGTCGGTGTCGCGTTCAGCCTGCTCGTGGGCG
GCGCGACGCTCGCGGTGGGCATGGTGCTGGGCGCGGCGGTGGCGCCGACCGATCCGGTGGCCGCGCTCGCCGTCGCCCGC
AAGGAGGGCCTGCCGCTCAACATCGTCACGCTGATCGAGGGCGAGGGACTGCTCAACGACGCGACCGCGCTGACCACGCT
CGCGGTCGCCGTCACCGTGGCGCGCGGGGCCGCGTTCTCGGCGCCGTCGGCGATCCGGGAGTTCGTGCTGGCGGCCGTCG
GCGGCCTGGTGGTGGGCCAGGTGTTCGCCTACGCCCGGCGCCTGCTGCGCCGGTGGCGGCACGACGTGCTGACCGCCAAC
GCCATCTCGCTGGCCACGCCGTTTCTCACCTATCTGGTCGCCGAAAAGCTGTCCGCCTCCGGCGTGCTGGCCGTCGTGGT
GTGCGGGCTGATCGTCGGCCACGACTCGCCGCGGGTGGAATCCGGGGCGAGCCGCCTGCAGACCCGCGCCGTCTGGCGGC
TGGTCAACTTCCTGCTCGAGGGCGTGGTGTTCCTGCTGATCGGCCATCAGGTGCCGGTGATCCTGGACGAGCTGGGCGGC
TACGCGTTGTCGACGATCCTGGTGGCGGTCGGGGTGACCGTCGCGGTGGTTCTGCTGGTCCGGCCGCTGTGGCTGCTGCT
CACCCAGGCGCTGCCCCGGTCGCTGCACACCCGGCTCGGCAACGTTGACGATTCGGCGACCGACAGCGCCGAGCCGCGGC
CCGAGCGCACCCGCGAGCGGCTCAGCGGCCGCGAGATCGTCGTGCTGAGCTGGGCCGGCACCCGCGGCGTGGTCAGCCTC
GCCGCGATCTTCGCGGTGCCGGTGCTGACCGAGGGCAACGCGCCGTTTCCCGACCGCGACCTGCTGCTGTTCTGCACCCT
GGTGGTGGTGCTGGTGACGCTGATCGGACAGGGTGTCACCTTCGGTCCGCTGGTGCGCGCCCTGGGCCTGCGCGCCAAGA
CCACCGACGAGCTGCGGCTGCGCAACCGGGCCCGGGCGGCCGCGCTGCGGGCCGCCCTGGACCGGCTCGACTCGCTGGAC
CCCGAGGACGGCGCCGACGTCGATCCCCGGGTAATCGACGGTGTGCGCCAACAGTTGTCGGCGCAGCTGGAGCGCTACGA
ACACCGGCTCACCCTGTTGTCGGACGTCGACGAGTTGCCCGCCGCCCCCGCCTACGAGGCCGCCGTGGGGCTGCGCCGGG
TGGCCATCGACGCCCAGCGCGACGAACTCGTGCGCTGGCGCGACGCGGGCATGCTGCCCGACCAGAGCCTGCGCGCGATC
GAACGCGAACTCGACCACGAGGAGAGCATGCTGCCGATGGGGTTGCCGCGATCCCCCCGGCGCAGTCAAAAGCGTTGA

Upstream 100 bases:

>100_bases
GCGGCGGTGGTCCCGGCCGGCACCCGGATCGGGGCTGGACAGGAATCGGTTGCGGGGACGGTCATTGTGGCGGTCTCCAA
GGCTCGCAGGGTCGACGACC

Downstream 100 bases:

>100_bases
GCCCCAGTTGATTTCAGGACCCGCTAGGGGCCAGCCAGGCCAGCGCGGCGACGGTCAGCGCCTCGGTGCCGGTGTCGAGG
GTGGGCTGGATGACGGGGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MLSGRPNGEQGRRVATVRSGTMRSMGAQTALTLLLAAIAVIVLVDWISERTRLPSATLLVLVGIGQALLPGPTIGLEPDV
VMTCILPPLLYHAALESSLVGIRRNLRTVVSLSVVLVLLTAASVGVAFSLLVGGATLAVGMVLGAAVAPTDPVAALAVAR
KEGLPLNIVTLIEGEGLLNDATALTTLAVAVTVARGAAFSAPSAIREFVLAAVGGLVVGQVFAYARRLLRRWRHDVLTAN
AISLATPFLTYLVAEKLSASGVLAVVVCGLIVGHDSPRVESGASRLQTRAVWRLVNFLLEGVVFLLIGHQVPVILDELGG
YALSTILVAVGVTVAVVLLVRPLWLLLTQALPRSLHTRLGNVDDSATDSAEPRPERTRERLSGREIVVLSWAGTRGVVSL
AAIFAVPVLTEGNAPFPDRDLLLFCTLVVVLVTLIGQGVTFGPLVRALGLRAKTTDELRLRNRARAAALRAALDRLDSLD
PEDGADVDPRVIDGVRQQLSAQLERYEHRLTLLSDVDELPAAPAYEAAVGLRRVAIDAQRDELVRWRDAGMLPDQSLRAI
ERELDHEESMLPMGLPRSPRRSQKR

Sequences:

>Translated_585_residues
MLSGRPNGEQGRRVATVRSGTMRSMGAQTALTLLLAAIAVIVLVDWISERTRLPSATLLVLVGIGQALLPGPTIGLEPDV
VMTCILPPLLYHAALESSLVGIRRNLRTVVSLSVVLVLLTAASVGVAFSLLVGGATLAVGMVLGAAVAPTDPVAALAVAR
KEGLPLNIVTLIEGEGLLNDATALTTLAVAVTVARGAAFSAPSAIREFVLAAVGGLVVGQVFAYARRLLRRWRHDVLTAN
AISLATPFLTYLVAEKLSASGVLAVVVCGLIVGHDSPRVESGASRLQTRAVWRLVNFLLEGVVFLLIGHQVPVILDELGG
YALSTILVAVGVTVAVVLLVRPLWLLLTQALPRSLHTRLGNVDDSATDSAEPRPERTRERLSGREIVVLSWAGTRGVVSL
AAIFAVPVLTEGNAPFPDRDLLLFCTLVVVLVTLIGQGVTFGPLVRALGLRAKTTDELRLRNRARAAALRAALDRLDSLD
PEDGADVDPRVIDGVRQQLSAQLERYEHRLTLLSDVDELPAAPAYEAAVGLRRVAIDAQRDELVRWRDAGMLPDQSLRAI
ERELDHEESMLPMGLPRSPRRSQKR
>Mature_585_residues
MLSGRPNGEQGRRVATVRSGTMRSMGAQTALTLLLAAIAVIVLVDWISERTRLPSATLLVLVGIGQALLPGPTIGLEPDV
VMTCILPPLLYHAALESSLVGIRRNLRTVVSLSVVLVLLTAASVGVAFSLLVGGATLAVGMVLGAAVAPTDPVAALAVAR
KEGLPLNIVTLIEGEGLLNDATALTTLAVAVTVARGAAFSAPSAIREFVLAAVGGLVVGQVFAYARRLLRRWRHDVLTAN
AISLATPFLTYLVAEKLSASGVLAVVVCGLIVGHDSPRVESGASRLQTRAVWRLVNFLLEGVVFLLIGHQVPVILDELGG
YALSTILVAVGVTVAVVLLVRPLWLLLTQALPRSLHTRLGNVDDSATDSAEPRPERTRERLSGREIVVLSWAGTRGVVSL
AAIFAVPVLTEGNAPFPDRDLLLFCTLVVVLVTLIGQGVTFGPLVRALGLRAKTTDELRLRNRARAAALRAALDRLDSLD
PEDGADVDPRVIDGVRQQLSAQLERYEHRLTLLSDVDELPAAPAYEAAVGLRRVAIDAQRDELVRWRDAGMLPDQSLRAI
ERELDHEESMLPMGLPRSPRRSQKR

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI194239733, Length=457, Percent_Identity=26.0393873085339, Blast_Score=106, Evalue=7e-23,
Organism=Homo sapiens, GI148727259, Length=452, Percent_Identity=21.4601769911504, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI15529998, Length=452, Percent_Identity=23.0088495575221, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI27734935, Length=316, Percent_Identity=22.4683544303797, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI294997330, Length=307, Percent_Identity=26.3843648208469, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI110227626, Length=307, Percent_Identity=26.3843648208469, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI5454070, Length=307, Percent_Identity=26.3843648208469, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI14211919, Length=402, Percent_Identity=24.3781094527363, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI4759144, Length=391, Percent_Identity=26.5984654731458, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1790501, Length=534, Percent_Identity=28.2771535580524, Blast_Score=158, Evalue=9e-40,
Organism=Caenorhabditis elegans, GI71992101, Length=296, Percent_Identity=24.3243243243243, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71992107, Length=296, Percent_Identity=24.3243243243243, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71999821, Length=565, Percent_Identity=20.8849557522124, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71999819, Length=588, Percent_Identity=21.4285714285714, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71999817, Length=588, Percent_Identity=21.4285714285714, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25147678, Length=453, Percent_Identity=24.7240618101545, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71987537, Length=435, Percent_Identity=21.8390804597701, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71987535, Length=435, Percent_Identity=21.8390804597701, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI25150332, Length=422, Percent_Identity=22.2748815165877, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71980847, Length=397, Percent_Identity=21.1586901763224, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71993590, Length=400, Percent_Identity=22.5, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71993582, Length=396, Percent_Identity=22.7272727272727, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320663, Length=283, Percent_Identity=21.9081272084806, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221473212, Length=467, Percent_Identity=24.1970021413276, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281364513, Length=414, Percent_Identity=25.1207729468599, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI221473222, Length=414, Percent_Identity=25.1207729468599, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI221473215, Length=414, Percent_Identity=25.1207729468599, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI221510738, Length=390, Percent_Identity=22.5641025641026, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24585580, Length=390, Percent_Identity=22.5641025641026, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24585578, Length=390, Percent_Identity=22.5641025641026, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221510732, Length=390, Percent_Identity=22.8205128205128, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221510736, Length=390, Percent_Identity=22.5641025641026, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221510734, Length=392, Percent_Identity=22.9591836734694, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221510740, Length=390, Percent_Identity=22.5641025641026, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281360447, Length=415, Percent_Identity=21.4457831325301, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 62371; Mature: 62371

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSGRPNGEQGRRVATVRSGTMRSMGAQTALTLLLAAIAVIVLVDWISERTRLPSATLLV
CCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LVGIGQALLPGPTIGLEPDVVMTCILPPLLYHAALESSLVGIRRNLRTVVSLSVVLVLLT
HHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AASVGVAFSLLVGGATLAVGMVLGAAVAPTDPVAALAVARKEGLPLNIVTLIEGEGLLND
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCH
ATALTTLAVAVTVARGAAFSAPSAIREFVLAAVGGLVVGQVFAYARRLLRRWRHDVLTAN
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AISLATPFLTYLVAEKLSASGVLAVVVCGLIVGHDSPRVESGASRLQTRAVWRLVNFLLE
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GVVFLLIGHQVPVILDELGGYALSTILVAVGVTVAVVLLVRPLWLLLTQALPRSLHTRLG
HHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NVDDSATDSAEPRPERTRERLSGREIVVLSWAGTRGVVSLAAIFAVPVLTEGNAPFPDRD
CCCCCCCCCCCCCHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHEECCCCCCCCHH
LLLFCTLVVVLVTLIGQGVTFGPLVRALGLRAKTTDELRLRNRARAAALRAALDRLDSLD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PEDGADVDPRVIDGVRQQLSAQLERYEHRLTLLSDVDELPAAPAYEAAVGLRRVAIDAQR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHH
DELVRWRDAGMLPDQSLRAIERELDHEESMLPMGLPRSPRRSQKR
HHHHHHHHCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLSGRPNGEQGRRVATVRSGTMRSMGAQTALTLLLAAIAVIVLVDWISERTRLPSATLLV
CCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LVGIGQALLPGPTIGLEPDVVMTCILPPLLYHAALESSLVGIRRNLRTVVSLSVVLVLLT
HHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AASVGVAFSLLVGGATLAVGMVLGAAVAPTDPVAALAVARKEGLPLNIVTLIEGEGLLND
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCH
ATALTTLAVAVTVARGAAFSAPSAIREFVLAAVGGLVVGQVFAYARRLLRRWRHDVLTAN
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AISLATPFLTYLVAEKLSASGVLAVVVCGLIVGHDSPRVESGASRLQTRAVWRLVNFLLE
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GVVFLLIGHQVPVILDELGGYALSTILVAVGVTVAVVLLVRPLWLLLTQALPRSLHTRLG
HHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NVDDSATDSAEPRPERTRERLSGREIVVLSWAGTRGVVSLAAIFAVPVLTEGNAPFPDRD
CCCCCCCCCCCCCHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHEECCCCCCCCHH
LLLFCTLVVVLVTLIGQGVTFGPLVRALGLRAKTTDELRLRNRARAAALRAALDRLDSLD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PEDGADVDPRVIDGVRQQLSAQLERYEHRLTLLSDVDELPAAPAYEAAVGLRRVAIDAQR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHH
DELVRWRDAGMLPDQSLRAIERELDHEESMLPMGLPRSPRRSQKR
HHHHHHHHCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]