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The map label for this gene is xseA

Identifier: 41408784

GI number: 41408784

Start: 3021118

End: 3022365

Strand: Direct

Name: xseA

Synonym: MAP2686

Alternate gene names: 41408784

Gene position: 3021118-3022365 (Clockwise)

Preceding gene: 41408783

Following gene: 41408785

Centisome position: 62.55

GC content: 72.6

Gene sequence:

>1248_bases
GTGACCCGAGCCGCTACCTCCGAACCGAACTCCGCCGAAAATCCATTTCCGGTGCGCGCGGTGGCAATCCGGGTCGCGGG
CTGGATCGACAGGCTGGGCACGGTGTGGGTGGAGGGTCAGCTGGCCCAGGTGTCGCTGCGGCCGGACTCCAAAACCGTGT
TCATGGTGCTGCGTGACCCGGCCGCCGACATGTCGCTGACCGTGACCTGCCCGCGCGACCTGGTGCTCAACGCCCCGGTG
AAACTGGCCGAAGGCACCCAGGTGGTCGTGTGCGGCAAGCCCTCGTTCTACACGGGCCGGGGCACGTTTTCGCTGCGGCT
GTCCGAGATCCGCGCCGTCGGGGTGGGCGAACTGCTGGCCCGCATCGAGCGGCTACGCCGGCTGCTGGACGCCGAAGGGC
TTTTCGACCCCCGCCTCAAGCGGCCAATTCCCTTCCTGCCCAACATGATCGGGCTGATCACCGGCCGGGCGAGCGCCGCC
GAGCGGGACGTGAAAACCGTCGCGGCGGGGCGCTGGCCCGCGGTGCGTTTCGCGGTGCGCAACACCGCGGTGCAGGGACC
CAACGCGGTCGCGCAGATCGTGGAGGCCCTGCGCGAACTCGACCGGGACCCCGAGGTCGACGTCATCGTGCTCGCCCGCG
GCGGCGGCAGCGTGGAGGACCTGTTGCCGTTCTCCGACGAGACGCTGTGCCGCGCCATCGCCGCCTGCCGCACCCCGGTG
ATCAGCGCGGTCGGTCACGAACCCGACAACCCGCTGTGCGATCTGGTCGCCGACGTGCGCGCGGCCACCCCCACCGACGC
CGCGAAGAAGGTGGTGCCCGACACCGCGGCCGAACAGCGGCTGATCGACGACCTGCGGCGGCGCAGCGCACAGGCGTTGC
GCAACTGGGTATCTCGCGAGCAACGCGCGCTGGCGCAGATCCGCAGCCGCCCGGTGCTGGCCGAGCCGTTGCGGGCGTTG
ACCGCACGCGCCGAGGAGGTGCACCGTGCCCGGTCGGCGATTCGGCACGACGTCACCCGGTTGACCGCCGCCGAAACCGA
GCGGATCGGCCACCTGCGCGCCCGGCTGGCGACGTTGGGCCCGGCGGCCACCCTGGCCCGCGGTTACGCCGTGGTGCAGA
CCGTCGGCGCCGGCGGCCCTCACGTGCTGCGTTCGGTGGGCGACGCGCCGGCGGGCACCCGGCTGCGGGTCCGGGTCGCC
GACGGCGCCGTGGCGGCGCTGAGCGAGGGACCGACCGATGGCGAATAA

Upstream 100 bases:

>100_bases
TGGACGAACTCGAGGCGCTGCTGGCCTACGAGCAGGCCACCAAGGGCCGGGCGCCGTTTCAGACGCTGCTGGCCAACAGG
ATCACCCGCGCGACCGCGAA

Downstream 100 bases:

>100_bases
CAAGAAGGACGAGCAGGCCGCCGCGGCTACACCTATTAGTCGACTGGGCTATGAGGCGTGCCGGGACGAACTGATCGAGG
TCGTGCGGCAACTGGAACAG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MTRAATSEPNSAENPFPVRAVAIRVAGWIDRLGTVWVEGQLAQVSLRPDSKTVFMVLRDPAADMSLTVTCPRDLVLNAPV
KLAEGTQVVVCGKPSFYTGRGTFSLRLSEIRAVGVGELLARIERLRRLLDAEGLFDPRLKRPIPFLPNMIGLITGRASAA
ERDVKTVAAGRWPAVRFAVRNTAVQGPNAVAQIVEALRELDRDPEVDVIVLARGGGSVEDLLPFSDETLCRAIAACRTPV
ISAVGHEPDNPLCDLVADVRAATPTDAAKKVVPDTAAEQRLIDDLRRRSAQALRNWVSREQRALAQIRSRPVLAEPLRAL
TARAEEVHRARSAIRHDVTRLTAAETERIGHLRARLATLGPAATLARGYAVVQTVGAGGPHVLRSVGDAPAGTRLRVRVA
DGAVAALSEGPTDGE

Sequences:

>Translated_415_residues
MTRAATSEPNSAENPFPVRAVAIRVAGWIDRLGTVWVEGQLAQVSLRPDSKTVFMVLRDPAADMSLTVTCPRDLVLNAPV
KLAEGTQVVVCGKPSFYTGRGTFSLRLSEIRAVGVGELLARIERLRRLLDAEGLFDPRLKRPIPFLPNMIGLITGRASAA
ERDVKTVAAGRWPAVRFAVRNTAVQGPNAVAQIVEALRELDRDPEVDVIVLARGGGSVEDLLPFSDETLCRAIAACRTPV
ISAVGHEPDNPLCDLVADVRAATPTDAAKKVVPDTAAEQRLIDDLRRRSAQALRNWVSREQRALAQIRSRPVLAEPLRAL
TARAEEVHRARSAIRHDVTRLTAAETERIGHLRARLATLGPAATLARGYAVVQTVGAGGPHVLRSVGDAPAGTRLRVRVA
DGAVAALSEGPTDGE
>Mature_414_residues
TRAATSEPNSAENPFPVRAVAIRVAGWIDRLGTVWVEGQLAQVSLRPDSKTVFMVLRDPAADMSLTVTCPRDLVLNAPVK
LAEGTQVVVCGKPSFYTGRGTFSLRLSEIRAVGVGELLARIERLRRLLDAEGLFDPRLKRPIPFLPNMIGLITGRASAAE
RDVKTVAAGRWPAVRFAVRNTAVQGPNAVAQIVEALRELDRDPEVDVIVLARGGGSVEDLLPFSDETLCRAIAACRTPVI
SAVGHEPDNPLCDLVADVRAATPTDAAKKVVPDTAAEQRLIDDLRRRSAQALRNWVSREQRALAQIRSRPVLAEPLRALT
ARAEEVHRARSAIRHDVTRLTAAETERIGHLRARLATLGPAATLARGYAVVQTVGAGGPHVLRSVGDAPAGTRLRVRVAD
GAVAALSEGPTDGE

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=420, Percent_Identity=30.952380952381, Blast_Score=183, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_MYCPA (Q73WH4)

Other databases:

- EMBL:   AE016958
- RefSeq:   NP_961620.1
- EnsemblBacteria:   EBMYCT00000038318
- GeneID:   2718843
- GenomeReviews:   AE016958_GR
- KEGG:   mpa:MAP2686
- NMPDR:   fig|262316.1.peg.2686
- GeneTree:   EBGT00050000016801
- HOGENOM:   HBG634411
- OMA:   PWPVRTV
- ProtClustDB:   PRK00286
- BRENDA:   3.1.11.6
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti

EC number: =3.1.11.6

Molecular weight: Translated: 44546; Mature: 44414

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRAATSEPNSAENPFPVRAVAIRVAGWIDRLGTVWVEGQLAQVSLRPDSKTVFMVLRDP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEECCEEEEEEECCCCCEEEEEEECC
AADMSLTVTCPRDLVLNAPVKLAEGTQVVVCGKPSFYTGRGTFSLRLSEIRAVGVGELLA
CCCCEEEEECCHHHEECCCEEECCCCEEEEECCCCEEECCCEEEEEHHHHHHCCHHHHHH
RIERLRRLLDAEGLFDPRLKRPIPFLPNMIGLITGRASAAERDVKTVAAGRWPAVRFAVR
HHHHHHHHHCCCCCCCCHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHH
NTAVQGPNAVAQIVEALRELDRDPEVDVIVLARGGGSVEDLLPFSDETLCRAIAACRTPV
HHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHHHHHH
ISAVGHEPDNPLCDLVADVRAATPTDAAKKVVPDTAAEQRLIDDLRRRSAQALRNWVSRE
HHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QRALAQIRSRPVLAEPLRALTARAEEVHRARSAIRHDVTRLTAAETERIGHLRARLATLG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PAATLARGYAVVQTVGAGGPHVLRSVGDAPAGTRLRVRVADGAVAALSEGPTDGE
HHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCEEEEEECCCCEEECCCCCCCCC
>Mature Secondary Structure 
TRAATSEPNSAENPFPVRAVAIRVAGWIDRLGTVWVEGQLAQVSLRPDSKTVFMVLRDP
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEECCEEEEEEECCCCCEEEEEEECC
AADMSLTVTCPRDLVLNAPVKLAEGTQVVVCGKPSFYTGRGTFSLRLSEIRAVGVGELLA
CCCCEEEEECCHHHEECCCEEECCCCEEEEECCCCEEECCCEEEEEHHHHHHCCHHHHHH
RIERLRRLLDAEGLFDPRLKRPIPFLPNMIGLITGRASAAERDVKTVAAGRWPAVRFAVR
HHHHHHHHHCCCCCCCCHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHH
NTAVQGPNAVAQIVEALRELDRDPEVDVIVLARGGGSVEDLLPFSDETLCRAIAACRTPV
HHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHHHHHH
ISAVGHEPDNPLCDLVADVRAATPTDAAKKVVPDTAAEQRLIDDLRRRSAQALRNWVSRE
HHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QRALAQIRSRPVLAEPLRALTARAEEVHRARSAIRHDVTRLTAAETERIGHLRARLATLG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PAATLARGYAVVQTVGAGGPHVLRSVGDAPAGTRLRVRVADGAVAALSEGPTDGE
HHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCEEEEEECCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA