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The map label for this gene is argS

Identifier: 41408568

GI number: 41408568

Start: 2775040

End: 2776692

Strand: Reverse

Name: argS

Synonym: MAP2470c

Alternate gene names: 41408568

Gene position: 2776692-2775040 (Counterclockwise)

Preceding gene: 41408572

Following gene: 41408567

Centisome position: 57.49

GC content: 69.15

Gene sequence:

>1653_bases
GTGACCCCCGCTGACCTCGCCGAGCTGCTCAGAAACACCGCCGCCGCGGTGCTGGCCGAGCGTGGGCTGGACGCGGCCGC
GTTGCCGGCGACGGTCGTCGTCGAGCGCCCCCGCAACCCCGAGCACGGCGACTACGCCAGCAACCTCGCGCTGCAGCTGG
GCAAAAAGGTCGGCGCCAATCCCCGCGAGCTGGCCGGATGGCTGGCCGCCGCGCTGGCCGAAACCGACGGCATCGCCTCG
GCGGAGGTGGCCGGCCCGGGCTTCATCAACCTGCGCCTCGAGGCGTCGGCGCAGGCCGTCGTCGTCACCAACGTGCTCGA
CGCCGGCGACCGCTACGGCCACTCCGACGCGCAATCCACCCACAACATCAACCTGGAATTCGTCTCGGCCAACCCCACCG
GGCCGATCCACATCGGCGGCACCCGCTGGGCCGCCGTCGGCGACGCGCTGGGCCGGCTGCTGTCCACCCAGGGCGCCGGC
GTGGTGCGCGAATACTATTTCAACGACCACGGCGCCCAGATCGACCGGTTCGCCAGCTCGCTGATCGCCGCCGCCAAGGG
CGAGCCGACGCCTGAAGACGGCTACGCCGGCAGCTACATCAACGACATCGCCGCCCAGGTGCTGCGCCAGGCGCCCGACG
CGCTGAGCCTGCCCGAGCCGCAGCTGCGCGAGACCTTCCGCGCCATCGGCGTCGACCTGATGTTCACCCACATCAAAGAG
TCGCTGCACGAGTTCGGCACCGACTTCGACGTGTACACCCACGAAGACTCGATGCACACCAGCGGCCGGGTCGACCAGGC
CATCGCCCGGCTGCGCGAAACCGGCAACATCTACGAGAAGGACGGCGCAACGTGGTTGCGCACCAGTGCATTTGGTGACG
ACAAAGACCGCGTGGTGATCAAGAGCGACGGCAAGCCCGCCTACATCGCCGGCGACATCGCCTACTACTTGGACAAGCGG
CAGCGCGGCTTCGACCTGTGCATCTACATGCTGGGCGCCGACCACCACGGCTACATCGCCCGGCTCAAGGCGGTCGCCGC
CGCGTTCGGCGACGACCCGGCCACCGTCGAGGTGCTCATCGGGCAGATGGTCAACCTGGTCCGCGACGGCCAGCCGGTCC
GGATGAGCAAACGGGCGGGAACCGTGATCACGCTCGACGATCTGGTCGAGGCGATCGGCGTCGACGCGGCGCGCTACAGC
CTGATTCGCTCCTCGGTGGACACCCCGATCGACATCGACCTGGCGCTGTGGTCCTCGGCGTCGAACGAAAACCCGGTCTA
CTACGTGCAATACGCGCACGCTCGGCTGTCCGCGCTGGCCCGTAATGCCGCCGAACTGGGCCTCATCCCCGACACCGCGC
ACTTGGAACTGCTCAGCCACGACAAGGAGGGGACGCTGCTGCGCACCCTCGGCGAATTCCCGCGGGTGCTCAAAACCGCG
GCGTCGCTGCGCGAGCCGCACCGGGTGTGCCGGTATCTGGAAGACCTGGCCGGTGACTACCACCGGTTCTACGACTCCTG
CCGGGTGCTGCCGCAGGGCGACGAGCAGCCCACCGATCTGCACACCGCCCGGCTGGCGCTGTGCCAGGCGACCCGGCAGG
TGATCGCCAACGGGCTGGCGATACTGGGCGTGACCGCTCCGGAGCGAATGTGA

Upstream 100 bases:

>100_bases
TTGCACCAATGGGCCCCGACAGCCTAACGCATCCGGATGACCGCTTCGTCACCGCAATGGATTCGGGGCGCGGGCACCTC
AGCCAATAGGATGGACGCTC

Downstream 100 bases:

>100_bases
ACGTCCACCCCGCCGGTCCTCGGCATGCCGAAGAGACCCGCCACCCCGAAAGCCCGCCGCGCCCGCAGTCTCCCGAGGAG
CTGTTGCTGCTCGCGCCGAA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MTPADLAELLRNTAAAVLAERGLDAAALPATVVVERPRNPEHGDYASNLALQLGKKVGANPRELAGWLAAALAETDGIAS
AEVAGPGFINLRLEASAQAVVVTNVLDAGDRYGHSDAQSTHNINLEFVSANPTGPIHIGGTRWAAVGDALGRLLSTQGAG
VVREYYFNDHGAQIDRFASSLIAAAKGEPTPEDGYAGSYINDIAAQVLRQAPDALSLPEPQLRETFRAIGVDLMFTHIKE
SLHEFGTDFDVYTHEDSMHTSGRVDQAIARLRETGNIYEKDGATWLRTSAFGDDKDRVVIKSDGKPAYIAGDIAYYLDKR
QRGFDLCIYMLGADHHGYIARLKAVAAAFGDDPATVEVLIGQMVNLVRDGQPVRMSKRAGTVITLDDLVEAIGVDAARYS
LIRSSVDTPIDIDLALWSSASNENPVYYVQYAHARLSALARNAAELGLIPDTAHLELLSHDKEGTLLRTLGEFPRVLKTA
ASLREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEQPTDLHTARLALCQATRQVIANGLAILGVTAPERM

Sequences:

>Translated_550_residues
MTPADLAELLRNTAAAVLAERGLDAAALPATVVVERPRNPEHGDYASNLALQLGKKVGANPRELAGWLAAALAETDGIAS
AEVAGPGFINLRLEASAQAVVVTNVLDAGDRYGHSDAQSTHNINLEFVSANPTGPIHIGGTRWAAVGDALGRLLSTQGAG
VVREYYFNDHGAQIDRFASSLIAAAKGEPTPEDGYAGSYINDIAAQVLRQAPDALSLPEPQLRETFRAIGVDLMFTHIKE
SLHEFGTDFDVYTHEDSMHTSGRVDQAIARLRETGNIYEKDGATWLRTSAFGDDKDRVVIKSDGKPAYIAGDIAYYLDKR
QRGFDLCIYMLGADHHGYIARLKAVAAAFGDDPATVEVLIGQMVNLVRDGQPVRMSKRAGTVITLDDLVEAIGVDAARYS
LIRSSVDTPIDIDLALWSSASNENPVYYVQYAHARLSALARNAAELGLIPDTAHLELLSHDKEGTLLRTLGEFPRVLKTA
ASLREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEQPTDLHTARLALCQATRQVIANGLAILGVTAPERM
>Mature_549_residues
TPADLAELLRNTAAAVLAERGLDAAALPATVVVERPRNPEHGDYASNLALQLGKKVGANPRELAGWLAAALAETDGIASA
EVAGPGFINLRLEASAQAVVVTNVLDAGDRYGHSDAQSTHNINLEFVSANPTGPIHIGGTRWAAVGDALGRLLSTQGAGV
VREYYFNDHGAQIDRFASSLIAAAKGEPTPEDGYAGSYINDIAAQVLRQAPDALSLPEPQLRETFRAIGVDLMFTHIKES
LHEFGTDFDVYTHEDSMHTSGRVDQAIARLRETGNIYEKDGATWLRTSAFGDDKDRVVIKSDGKPAYIAGDIAYYLDKRQ
RGFDLCIYMLGADHHGYIARLKAVAAAFGDDPATVEVLIGQMVNLVRDGQPVRMSKRAGTVITLDDLVEAIGVDAARYSL
IRSSVDTPIDIDLALWSSASNENPVYYVQYAHARLSALARNAAELGLIPDTAHLELLSHDKEGTLLRTLGEFPRVLKTAA
SLREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEQPTDLHTARLALCQATRQVIANGLAILGVTAPERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1788184, Length=591, Percent_Identity=27.2419627749577, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6320548, Length=603, Percent_Identity=26.3681592039801, Blast_Score=143, Evalue=6e-35,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_MYCPA (Q73X40)

Other databases:

- EMBL:   AE016958
- RefSeq:   NP_961404.1
- ProteinModelPortal:   Q73X40
- EnsemblBacteria:   EBMYCT00000039750
- GeneID:   2718076
- GenomeReviews:   AE016958_GR
- KEGG:   mpa:MAP2470c
- NMPDR:   fig|262316.1.peg.2470
- GeneTree:   EBGT00050000016532
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- BRENDA:   6.1.1.19
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 59470; Mature: 59338

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPADLAELLRNTAAAVLAERGLDAAALPATVVVERPRNPEHGDYASNLALQLGKKVGAN
CCHHHHHHHHHHHHHHHHHHCCCCCHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCC
PRELAGWLAAALAETDGIASAEVAGPGFINLRLEASAQAVVVTNVLDAGDRYGHSDAQST
HHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCEEEEEHHHHCCCCCCCCCCCCC
HNINLEFVSANPTGPIHIGGTRWAAVGDALGRLLSTQGAGVVREYYFNDHGAQIDRFASS
CCEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHCCCCCHHHHHEECCCCCHHHHHHHH
LIAAAKGEPTPEDGYAGSYINDIAAQVLRQAPDALSLPEPQLRETFRAIGVDLMFTHIKE
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SLHEFGTDFDVYTHEDSMHTSGRVDQAIARLRETGNIYEKDGATWLRTSAFGDDKDRVVI
HHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCEEECCCCCEEEECCCCCCCCEEEE
KSDGKPAYIAGDIAYYLDKRQRGFDLCIYMLGADHHGYIARLKAVAAAFGDDPATVEVLI
ECCCCCEEEEHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHH
GQMVNLVRDGQPVRMSKRAGTVITLDDLVEAIGVDAARYSLIRSSVDTPIDIDLALWSSA
HHHHHHHHCCCCCEECCCCCCEEEHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEEECCC
SNENPVYYVQYAHARLSALARNAAELGLIPDTAHLELLSHDKEGTLLRTLGEFPRVLKTA
CCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ASLREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEQPTDLHTARLALCQATRQVIANGLA
HHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEE
ILGVTAPERM
EEEECCCCCC
>Mature Secondary Structure 
TPADLAELLRNTAAAVLAERGLDAAALPATVVVERPRNPEHGDYASNLALQLGKKVGAN
CHHHHHHHHHHHHHHHHHHCCCCCHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCC
PRELAGWLAAALAETDGIASAEVAGPGFINLRLEASAQAVVVTNVLDAGDRYGHSDAQST
HHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCEEEEEHHHHCCCCCCCCCCCCC
HNINLEFVSANPTGPIHIGGTRWAAVGDALGRLLSTQGAGVVREYYFNDHGAQIDRFASS
CCEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHCCCCCHHHHHEECCCCCHHHHHHHH
LIAAAKGEPTPEDGYAGSYINDIAAQVLRQAPDALSLPEPQLRETFRAIGVDLMFTHIKE
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SLHEFGTDFDVYTHEDSMHTSGRVDQAIARLRETGNIYEKDGATWLRTSAFGDDKDRVVI
HHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCEEECCCCCEEEECCCCCCCCEEEE
KSDGKPAYIAGDIAYYLDKRQRGFDLCIYMLGADHHGYIARLKAVAAAFGDDPATVEVLI
ECCCCCEEEEHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHH
GQMVNLVRDGQPVRMSKRAGTVITLDDLVEAIGVDAARYSLIRSSVDTPIDIDLALWSSA
HHHHHHHHCCCCCEECCCCCCEEEHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEEECCC
SNENPVYYVQYAHARLSALARNAAELGLIPDTAHLELLSHDKEGTLLRTLGEFPRVLKTA
CCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ASLREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEQPTDLHTARLALCQATRQVIANGLA
HHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEE
ILGVTAPERM
EEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA