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The map label for this gene is thrC

Identifier: 41408565

GI number: 41408565

Start: 2771217

End: 2772299

Strand: Reverse

Name: thrC

Synonym: MAP2467c

Alternate gene names: 41408565

Gene position: 2772299-2771217 (Counterclockwise)

Preceding gene: 41408566

Following gene: 41408564

Centisome position: 57.4

GC content: 70.27

Gene sequence:

>1083_bases
ATGAGCGCCCAGCGCACCGCCGTCCATCAGCCCTGGCCCGGCCTCATCGAGGCCTACCGAGACCGGCTGCCGGTGGGCGA
CGACTGGACCCCGGTGACCCTGCTCGAGGGCGGCACCCCGCTGATCCCGGCCCGCCGGCTCTCGGAAAAGACCGGCTGCA
CAGTCCATCTCAAGGTCGAGGGCCTCAACCCCACCGGCTCCTTCAAGGACCGCGGCATGACGATGGCGGTCACCGACGCG
CTGGCGCGCGGCCAGCAGGCGGTGCTGTGTGCCTCCACCGGCAACACCTCGGCGTCGGCGGCGGCCTATGCGGCCCGTGC
CGGCATCACCTGCGCGGTGCTGATCCCGCAGGGCAAGATCGCGATGGGCAAGCTCGCGCAGGCGGTCATGCACGGCGCCA
AGATCATTCAGATCGACGGCAACTTCGACGACTGCCTGGAACTGGCCCGCAAGATGGCCGCCGACTTCCCGACGATCTCG
TTGGTCAATTCGGTCAACCCGGTGCGCATCGAGGGTCAGAAGACCGCGGCGTTCGAGATCGTCGATGTGCTGGGCGCCGC
GCCTGACGTGCACGCGCTTCCGGTCGGCAACGCCGGCAACATCACCGCGTACTGGAAGGGATACACCGAGTATCACCACG
AGGGCCTGATCGAGAAGCTGCCCCGCATGCTCGGCACCCAGGCCGCCGGGGCGGCCCCGCTCGTGCACGGCGAGCCGGTC
AAAAACCCCGAGACCATCGCGACCGCGATCCGCATCGGCGCGCCGGCATCGTGGACCGCGGCCGTCGACGCGCAGCAGCA
ATCCCACGGCCGCTTCCTGGCGGCCACCGACGACGAGATCCTGGCCGCCTATCATCTGGTCGCCGAGTCCGAGGGCGTGT
TCGTCGAACCCGCGTCGGCCGCCAGCATCGCGGGACTGCTGAAGGCGGTCGAGGACGGCTGGGTGGCGCGCGGGTCGACG
GTGGTGTGCACGGTGACCGGCAACGGCCTGAAGGATCCGGACACCGCGCTGCGGGACATGCCGGCCGTGACGCCGCTGCC
GGTCGACCCGGTCCTGGTGGTCGAGAAGCTCGGGCTGGCCTGA

Upstream 100 bases:

>100_bases
CCGCCACCGATGCCGCGCTTTCCGAAACCGTGCATGCGCTCGCCGATTTGGACGTCGTGCAGAGCGTGACGAGCGTGCTG
CGACTGGAAGGGACCAGCCT

Downstream 100 bases:

>100_bases
CGAATGGGCGCGCTCGCAACGAAAGGCTGTTGGTGACCTCCATGCTGCCCGCCGGGCTGGTGGCCTCCGCCGTCGTGTCG
GCGTCCAGTGCCAATCTCGG

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MSAQRTAVHQPWPGLIEAYRDRLPVGDDWTPVTLLEGGTPLIPARRLSEKTGCTVHLKVEGLNPTGSFKDRGMTMAVTDA
LARGQQAVLCASTGNTSASAAAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELARKMAADFPTIS
LVNSVNPVRIEGQKTAAFEIVDVLGAAPDVHALPVGNAGNITAYWKGYTEYHHEGLIEKLPRMLGTQAAGAAPLVHGEPV
KNPETIATAIRIGAPASWTAAVDAQQQSHGRFLAATDDEILAAYHLVAESEGVFVEPASAASIAGLLKAVEDGWVARGST
VVCTVTGNGLKDPDTALRDMPAVTPLPVDPVLVVEKLGLA

Sequences:

>Translated_360_residues
MSAQRTAVHQPWPGLIEAYRDRLPVGDDWTPVTLLEGGTPLIPARRLSEKTGCTVHLKVEGLNPTGSFKDRGMTMAVTDA
LARGQQAVLCASTGNTSASAAAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELARKMAADFPTIS
LVNSVNPVRIEGQKTAAFEIVDVLGAAPDVHALPVGNAGNITAYWKGYTEYHHEGLIEKLPRMLGTQAAGAAPLVHGEPV
KNPETIATAIRIGAPASWTAAVDAQQQSHGRFLAATDDEILAAYHLVAESEGVFVEPASAASIAGLLKAVEDGWVARGST
VVCTVTGNGLKDPDTALRDMPAVTPLPVDPVLVVEKLGLA
>Mature_359_residues
SAQRTAVHQPWPGLIEAYRDRLPVGDDWTPVTLLEGGTPLIPARRLSEKTGCTVHLKVEGLNPTGSFKDRGMTMAVTDAL
ARGQQAVLCASTGNTSASAAAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELARKMAADFPTISL
VNSVNPVRIEGQKTAAFEIVDVLGAAPDVHALPVGNAGNITAYWKGYTEYHHEGLIEKLPRMLGTQAAGAAPLVHGEPVK
NPETIATAIRIGAPASWTAAVDAQQQSHGRFLAATDDEILAAYHLVAESEGVFVEPASAASIAGLLKAVEDGWVARGSTV
VCTVTGNGLKDPDTALRDMPAVTPLPVDPVLVVEKLGLA

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322631, Length=278, Percent_Identity=25.8992805755396, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 37598; Mature: 37467

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQRTAVHQPWPGLIEAYRDRLPVGDDWTPVTLLEGGTPLIPARRLSEKTGCTVHLKVE
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHCCCCEEEEEEE
GLNPTGSFKDRGMTMAVTDALARGQQAVLCASTGNTSASAAAYAARAGITCAVLIPQGKI
CCCCCCCCCCCCCEEEEHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCC
AMGKLAQAVMHGAKIIQIDGNFDDCLELARKMAADFPTISLVNSVNPVRIEGQKTAAFEI
HHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCCEEHHCCCCCEEEECCCHHHHHH
VDVLGAAPDVHALPVGNAGNITAYWKGYTEYHHEGLIEKLPRMLGTQAAGAAPLVHGEPV
HHHHCCCCCCEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
KNPETIATAIRIGAPASWTAAVDAQQQSHGRFLAATDDEILAAYHLVAESEGVFVEPASA
CCHHHHHHEEEECCCCCCEEEECCCHHHCCCEEEECCCHHHHHHHHHCCCCCCEECCCCH
ASIAGLLKAVEDGWVARGSTVVCTVTGNGLKDPDTALRDMPAVTPLPVDPVLVVEKLGLA
HHHHHHHHHHHCCCEECCCEEEEEEECCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
SAQRTAVHQPWPGLIEAYRDRLPVGDDWTPVTLLEGGTPLIPARRLSEKTGCTVHLKVE
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHCCCCEEEEEEE
GLNPTGSFKDRGMTMAVTDALARGQQAVLCASTGNTSASAAAYAARAGITCAVLIPQGKI
CCCCCCCCCCCCCEEEEHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCC
AMGKLAQAVMHGAKIIQIDGNFDDCLELARKMAADFPTISLVNSVNPVRIEGQKTAAFEI
HHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCCEEHHCCCCCEEEECCCHHHHHH
VDVLGAAPDVHALPVGNAGNITAYWKGYTEYHHEGLIEKLPRMLGTQAAGAAPLVHGEPV
HHHHCCCCCCEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
KNPETIATAIRIGAPASWTAAVDAQQQSHGRFLAATDDEILAAYHLVAESEGVFVEPASA
CCHHHHHHEEEECCCCCCEEEECCCHHHCCCEEEECCCHHHHHHHHHCCCCCCEECCCCH
ASIAGLLKAVEDGWVARGSTVVCTVTGNGLKDPDTALRDMPAVTPLPVDPVLVVEKLGLA
HHHHHHHHHHHCCCEECCCEEEEEEECCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA