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The map label for this gene is atpB

Identifier: 41408555

GI number: 41408555

Start: 2762329

End: 2763087

Strand: Reverse

Name: atpB

Synonym: MAP2457c

Alternate gene names: 41408555

Gene position: 2763087-2762329 (Counterclockwise)

Preceding gene: 41408556

Following gene: 41408554

Centisome position: 57.21

GC content: 62.85

Gene sequence:

>759_bases
ATGCCTGAGACGACGTTCCTGGCCGAATCCGCCATCGAGGTCGGCGAACACAACCACGCCACCTGGTTGGGCATGACCGT
CAACACCGACACGATTCTGTCGACCGGGATCGCCGCGCTGATCGTCCTCGCGCTGGCCTTCTTCCTGCGCGCGAAGATCA
CCTCCACCGGCGTGCCCAGCGGCGTCCAGTTGTTCTGGGAGGCCATCACGGTCCAGATGCGCGATCAGATCGAGAGCGCG
GTCGGCATGCGGATCGCGCCGTTCGTGTTGCCGCTGGCCGTCACCATCTTCGTGTTCATCCTGATCTCCAACTGGCTGTC
GGTGCTTCCGCTGCAGTACACGGACAAGTCCGGGCACACCACCGAGCTGCTGAAGTCGGTGGCCGCGGACATCAATTACG
TTCTGGCGCTGGCTCTTTTCGTCTTCGTCTGCTACCACGTGGCCGGCATCTGGCGTCGCGGCGTCGTCGGGCACCCGCTG
GCCGTGCTCAAGGGTCACGTGGCGTTCCTGGCGCCGATCAACGTCGTCGAGGAGTTGGCCAAGCCAATCTCGTTGTCGCT
GCGACTTTTCGGCAACATCTTCGCCGGCGGCATCCTGGTCGCGCTGATCGCGCTGTTCCCGCCCTACATCATGTGGGCCC
CCAACGCGATCTGGAAAGCCTTCGACCTGTTCGTCGGCGCGATCCAGGCCTTCATCTTCTCGATCCTGACCATCCTGTAC
TTCAGCCAGGCCATGGAGATCGAGGAACACCATGACTGA

Upstream 100 bases:

>100_bases
GCGCTGCCGGTGTGGAAGAAACTGCGTGCCGGTGACTGGGCGCCGTCCGCCGACGGCGCCGCCGCGGGGTCGGACGGAAC
GGAAGGAAGGAACAGCACCG

Downstream 100 bases:

>100_bases
GACCACCACGAATTGCCTTGACCCACGCACGATTTCGACAAGCCTGGTAGACCCCTACCAGTTACAAGGAGGATAAGAAT
GGCTCTGGACCCCCAAGTCG

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MPETTFLAESAIEVGEHNHATWLGMTVNTDTILSTGIAALIVLALAFFLRAKITSTGVPSGVQLFWEAITVQMRDQIESA
VGMRIAPFVLPLAVTIFVFILISNWLSVLPLQYTDKSGHTTELLKSVAADINYVLALALFVFVCYHVAGIWRRGVVGHPL
AVLKGHVAFLAPINVVEELAKPISLSLRLFGNIFAGGILVALIALFPPYIMWAPNAIWKAFDLFVGAIQAFIFSILTILY
FSQAMEIEEHHD

Sequences:

>Translated_252_residues
MPETTFLAESAIEVGEHNHATWLGMTVNTDTILSTGIAALIVLALAFFLRAKITSTGVPSGVQLFWEAITVQMRDQIESA
VGMRIAPFVLPLAVTIFVFILISNWLSVLPLQYTDKSGHTTELLKSVAADINYVLALALFVFVCYHVAGIWRRGVVGHPL
AVLKGHVAFLAPINVVEELAKPISLSLRLFGNIFAGGILVALIALFPPYIMWAPNAIWKAFDLFVGAIQAFIFSILTILY
FSQAMEIEEHHD
>Mature_251_residues
PETTFLAESAIEVGEHNHATWLGMTVNTDTILSTGIAALIVLALAFFLRAKITSTGVPSGVQLFWEAITVQMRDQIESAV
GMRIAPFVLPLAVTIFVFILISNWLSVLPLQYTDKSGHTTELLKSVAADINYVLALALFVFVCYHVAGIWRRGVVGHPLA
VLKGHVAFLAPINVVEELAKPISLSLRLFGNIFAGGILVALIALFPPYIMWAPNAIWKAFDLFVGAIQAFIFSILTILYF
SQAMEIEEHHD

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=212, Percent_Identity=34.9056603773585, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 27636; Mature: 27505

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPETTFLAESAIEVGEHNHATWLGMTVNTDTILSTGIAALIVLALAFFLRAKITSTGVPS
CCCCHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
GVQLFWEAITVQMRDQIESAVGMRIAPFVLPLAVTIFVFILISNWLSVLPLQYTDKSGHT
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
TELLKSVAADINYVLALALFVFVCYHVAGIWRRGVVGHPLAVLKGHVAFLAPINVVEELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KPISLSLRLFGNIFAGGILVALIALFPPYIMWAPNAIWKAFDLFVGAIQAFIFSILTILY
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FSQAMEIEEHHD
HHHHHHHHHCCC
>Mature Secondary Structure 
PETTFLAESAIEVGEHNHATWLGMTVNTDTILSTGIAALIVLALAFFLRAKITSTGVPS
CCCHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
GVQLFWEAITVQMRDQIESAVGMRIAPFVLPLAVTIFVFILISNWLSVLPLQYTDKSGHT
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
TELLKSVAADINYVLALALFVFVCYHVAGIWRRGVVGHPLAVLKGHVAFLAPINVVEELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KPISLSLRLFGNIFAGGILVALIALFPPYIMWAPNAIWKAFDLFVGAIQAFIFSILTILY
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FSQAMEIEEHHD
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]