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The map label for this gene is murA

Identifier: 41408545

GI number: 41408545

Start: 2753171

End: 2754424

Strand: Reverse

Name: murA

Synonym: MAP2447c

Alternate gene names: 41408545

Gene position: 2754424-2753171 (Counterclockwise)

Preceding gene: 41408547

Following gene: 41408544

Centisome position: 57.03

GC content: 69.54

Gene sequence:

>1254_bases
GTGGCCGAGCGATTCGTGGTGACCGGCGGCAACCGGTTGTCCGGCGAAGTCGCAGTGGGGGGCGCCAAGAACAGCGTGCT
CAAGCTGATGGCCGCGACCCTGCTGGCCGAGGGCACCAGCACCATCACCAACTGCCCCGACATCCTGGACGTGCCGCTGA
TGGCCGAGGTGCTGCGCGGCCTGGGCGCCACCGTCGAACTCGACGGCGACGTCGCCCGCATCACCTCTCCCGACGAGCCG
AAATACGACGCCGACTTCGCCGCGGTGCGACAGTTCCGGGCCTCGGTGTGCGTGCTGGGGCCGCTGGTCGGCCGGTGCAA
GCGCGCCCGGGTCGCGCTGCCCGGTGGCGATGCCATCGGGTCGCGCCCGCTGGACATGCATCAGGCCGGCCTGCGCCAGC
TGGGCGCCACCTGCAACATCGAGCACGGATGCGTGGTGGCGCAGGCGGATACGTTGCGCGGCGCGGAGATTCAGCTGGAG
TTCCCGTCGGTGGGGGCGACCGAGAACATCCTGATGGCGGCGGTGGTGGCCGAGGGGGTCACCACCATTCACAACGCGGC
CCGCGAACCCGACGTGGTGGATCTGTGCACGATGCTCAACCAGATGGGCGCGCAGGTCGAGGGCGCGGGTTCGCCGACCA
TGACCATCACCGGCGTGCCGCGGCTGTACCCGACCGAACATCGGGTGATCGGCGACCGCATCGTGGCCGCGACCTGGGGC
ATCGCCGCGGCGATGACCCGCGGGGACATCTCGGTGACCGGCGTCGACCCCGCCCACCTGCAGGTGGTGCTGCACAAGTT
GCACGATGCCGGGGCCACCGTGACCCAGACCGACGACAGCTTCCGGGTGACCCAGTACGAGCGGCCCAAGGCGGTTAACG
TGGCCACCCTGCCGTTTCCCGGATTTCCCACCGACCTGCAGCCGATGGCGATCGCCCTGGCGTCGATCGCCGATGGCACC
TCGATGATCACCGAGAACGTGTTCGAGGCGCGCTTCCGGTTCGTCGAGGAAATGATCCGGCTGGGCGCCGACGCCCGCAC
CGACGGGCACCACGCGGTGGTGCGCGGGCTGCCGCAATTGTCCAGTGCGCCCGTGTGGTGTTCGGACATTCGGGCCGGCG
CCGGCCTGGTGTTGGCGGGGCTGGTGGCCGACGGGGACACCGAGGTGCACGACGTCTTCCACATCGACCGCGGCTACCCG
TTGTTCGTGGAAAACCTGGCGATTTTGGGAGCGGAGATCGAGCGGGTAGAGTAG

Upstream 100 bases:

>100_bases
TCAGATGCACTGCCATGACCAAAACGGTACTGCGGCGCCCGGGCGGGACCGAGCCTTGGCTGACTGACAAAGCCGACACC
GCTTCACTAGACTGACCCGG

Downstream 100 bases:

>100_bases
CCAAAGTCAGTGCCCCACAAGCGAGGTCACCAACGCGAAGGTGAACGAGATCGGGGCCTTGACTCCCTCGCCGGATTGGT
ACTAGCCTGGCACGGCTGCT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MAERFVVTGGNRLSGEVAVGGAKNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGDVARITSPDEP
KYDADFAAVRQFRASVCVLGPLVGRCKRARVALPGGDAIGSRPLDMHQAGLRQLGATCNIEHGCVVAQADTLRGAEIQLE
FPSVGATENILMAAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQVEGAGSPTMTITGVPRLYPTEHRVIGDRIVAATWG
IAAAMTRGDISVTGVDPAHLQVVLHKLHDAGATVTQTDDSFRVTQYERPKAVNVATLPFPGFPTDLQPMAIALASIADGT
SMITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQLSSAPVWCSDIRAGAGLVLAGLVADGDTEVHDVFHIDRGYP
LFVENLAILGAEIERVE

Sequences:

>Translated_417_residues
MAERFVVTGGNRLSGEVAVGGAKNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGDVARITSPDEP
KYDADFAAVRQFRASVCVLGPLVGRCKRARVALPGGDAIGSRPLDMHQAGLRQLGATCNIEHGCVVAQADTLRGAEIQLE
FPSVGATENILMAAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQVEGAGSPTMTITGVPRLYPTEHRVIGDRIVAATWG
IAAAMTRGDISVTGVDPAHLQVVLHKLHDAGATVTQTDDSFRVTQYERPKAVNVATLPFPGFPTDLQPMAIALASIADGT
SMITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQLSSAPVWCSDIRAGAGLVLAGLVADGDTEVHDVFHIDRGYP
LFVENLAILGAEIERVE
>Mature_416_residues
AERFVVTGGNRLSGEVAVGGAKNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGDVARITSPDEPK
YDADFAAVRQFRASVCVLGPLVGRCKRARVALPGGDAIGSRPLDMHQAGLRQLGATCNIEHGCVVAQADTLRGAEIQLEF
PSVGATENILMAAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQVEGAGSPTMTITGVPRLYPTEHRVIGDRIVAATWGI
AAAMTRGDISVTGVDPAHLQVVLHKLHDAGATVTQTDDSFRVTQYERPKAVNVATLPFPGFPTDLQPMAIALASIADGTS
MITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQLSSAPVWCSDIRAGAGLVLAGLVADGDTEVHDVFHIDRGYPL
FVENLAILGAEIERVE

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=417, Percent_Identity=45.3237410071942, Blast_Score=327, Evalue=1e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44009; Mature: 43878

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERFVVTGGNRLSGEVAVGGAKNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRG
CCCEEEEECCCEECCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHCHHHHHHHHHH
LGATVELDGDVARITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKRARVALPGGDAIG
CCCEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCC
SRPLDMHQAGLRQLGATCNIEHGCVVAQADTLRGAEIQLEFPSVGATENILMAAVVAEGV
CCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
TTIHNAAREPDVVDLCTMLNQMGAQVEGAGSPTMTITGVPRLYPTEHRVIGDRIVAATWG
HHHHHHCCCCCHHHHHHHHHHHCCEEECCCCCEEEEECCCCCCCCCHHHHHCCHHHHHHH
IAAAMTRGDISVTGVDPAHLQVVLHKLHDAGATVTQTDDSFRVTQYERPKAVNVATLPFP
HHHHEECCCEEEECCCHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCEEEEEECCCC
GFPTDLQPMAIALASIADGTSMITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQL
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCC
SSAPVWCSDIRAGAGLVLAGLVADGDTEVHDVFHIDRGYPLFVENLAILGAEIERVE
CCCCCCHHHHCCCCCEEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHCCHHHCCC
>Mature Secondary Structure 
AERFVVTGGNRLSGEVAVGGAKNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRG
CCEEEEECCCEECCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHCHHHHHHHHHH
LGATVELDGDVARITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKRARVALPGGDAIG
CCCEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCC
SRPLDMHQAGLRQLGATCNIEHGCVVAQADTLRGAEIQLEFPSVGATENILMAAVVAEGV
CCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
TTIHNAAREPDVVDLCTMLNQMGAQVEGAGSPTMTITGVPRLYPTEHRVIGDRIVAATWG
HHHHHHCCCCCHHHHHHHHHHHCCEEECCCCCEEEEECCCCCCCCCHHHHHCCHHHHHHH
IAAAMTRGDISVTGVDPAHLQVVLHKLHDAGATVTQTDDSFRVTQYERPKAVNVATLPFP
HHHHEECCCEEEECCCHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCEEEEEECCCC
GFPTDLQPMAIALASIADGTSMITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQL
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCC
SSAPVWCSDIRAGAGLVLAGLVADGDTEVHDVFHIDRGYPLFVENLAILGAEIERVE
CCCCCCHHHHCCCCCEEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]