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The map label for this gene is acdA [H]

Identifier: 41408460

GI number: 41408460

Start: 2654302

End: 2655543

Strand: Reverse

Name: acdA [H]

Synonym: MAP2362c

Alternate gene names: 41408460

Gene position: 2655543-2654302 (Counterclockwise)

Preceding gene: 41408461

Following gene: 41408458

Centisome position: 54.98

GC content: 69.48

Gene sequence:

>1242_bases
ATGACGACCGAATCCGTCGCGCAATTCGCGGCCCGGGCGCGAGCCTGGTTGGCCGACAACATGCCCGCCATCGACCGCGA
GTCCCCACCACCGGCCCCGCGCGACGACGAGCGGGCCTGGCGCAGGGCCCGCGAACTGCAGAAGCGGCTGTACGACGGCG
GTTTCGCGGGCATATGCTTTCCCCGCGAGTACGGCGGCCTGGGACTGGACTACGAATACCAGAAGGCATTCGACGCCGAA
AGCCTCGACTATGAAATGCCGTTGATCCTCAACACCCCGACCTTCACCATCTGCTGCGCGACGCTGCTCGACACCGCCAG
CGAGCAGCAGAAGGAACAGCACATCGCCGCGGCACTGCGCGGCGAGGAAATCCTGGTGCAGCTGTTGAGCGAACCCAGCG
GCAGGTCGGATCTGGCCGGTGTGCTCACCCGGGCCGAGCGGCGCGGCGACCGGTGGATCATCAACGGCGCCAAGACCTGG
AGCACGAGCGCGTTCGCCGCCGACTACGGCCTGTGCCTGGCCCGCACCAACTGGGACGTGCCCAAGCACGAAGGCCTGAC
CATGTTCCTGGTGCCCATCAACCATCCCGGAATCACGTTGCGGCGCATCACCATGCTCAGCGGCTCCACCGAGTTCTGCG
AGGAGTTCCTGGACGGTGTCGACGTGGGGGATGACGCCGTCGTCGGGGAGGTCAACGGCGGCTGGGCGGTGGCCTCACGC
CAGCTCTACCACGAACGCCGGGCCGTGGGGCAGGGTTCCGAATTCGCCAGCGGGGGCGGCAGCGAGGGCGGCCACACGAT
CCCGGTCGACTACGTGAGCCTGGCCGAGAAGACCGGACAGGCCGACGACCCGCGCGTGCAGGAGATGGCCGGTCGCGTCC
TGGTGCACCGCGCGGTGGCCGAGCAGCTGATCGGCCACGTGTACCGCAGCGTCCGGGACGGCGCACTGCCGCCGGCCGCC
GGAACGCTGATCCGGCTGTTCCACTCCGAAACCGTCACCACCGACGTCGACACCGCGCTGGCGATCGCGGGCAGCGCCGG
TGTGGTCGGGGAGCCGGGCGCCGGACTGGAAACCGGGCTGCGCTACCTGTCCCGGCAGACCGTCGCCATCGGCGGTGGCA
CAACGGAAATGGCGCGCAACGTCATCGGCGAGCGGGTGCTGGGCTTCCCCCGGGAATACGCCGCCGACCGCGGGGTGCCG
TTCAACCAGGTGCGGCACGGGCAGCGCTCGGATCGGTCCTAA

Upstream 100 bases:

>100_bases
TGTACCTGCGCCGGGTTACGTTGTACCGCGGCATGTTCGGCACGCCGGAGGAACACAACCTGCGCGTCTACCAGTTCGAG
AAGGCGGGGCGTGCGGCGAA

Downstream 100 bases:

>100_bases
CCTTCGGCGACGACGTTCTCGGCGAGGCCGCTGACCACCGGGATCTGCACCAGCGACAGGACGTGGTGGGCCGGGCTTCC
CGGCGGGGCCACCAGCACGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MTTESVAQFAARARAWLADNMPAIDRESPPPAPRDDERAWRRARELQKRLYDGGFAGICFPREYGGLGLDYEYQKAFDAE
SLDYEMPLILNTPTFTICCATLLDTASEQQKEQHIAAALRGEEILVQLLSEPSGRSDLAGVLTRAERRGDRWIINGAKTW
STSAFAADYGLCLARTNWDVPKHEGLTMFLVPINHPGITLRRITMLSGSTEFCEEFLDGVDVGDDAVVGEVNGGWAVASR
QLYHERRAVGQGSEFASGGGSEGGHTIPVDYVSLAEKTGQADDPRVQEMAGRVLVHRAVAEQLIGHVYRSVRDGALPPAA
GTLIRLFHSETVTTDVDTALAIAGSAGVVGEPGAGLETGLRYLSRQTVAIGGGTTEMARNVIGERVLGFPREYAADRGVP
FNQVRHGQRSDRS

Sequences:

>Translated_413_residues
MTTESVAQFAARARAWLADNMPAIDRESPPPAPRDDERAWRRARELQKRLYDGGFAGICFPREYGGLGLDYEYQKAFDAE
SLDYEMPLILNTPTFTICCATLLDTASEQQKEQHIAAALRGEEILVQLLSEPSGRSDLAGVLTRAERRGDRWIINGAKTW
STSAFAADYGLCLARTNWDVPKHEGLTMFLVPINHPGITLRRITMLSGSTEFCEEFLDGVDVGDDAVVGEVNGGWAVASR
QLYHERRAVGQGSEFASGGGSEGGHTIPVDYVSLAEKTGQADDPRVQEMAGRVLVHRAVAEQLIGHVYRSVRDGALPPAA
GTLIRLFHSETVTTDVDTALAIAGSAGVVGEPGAGLETGLRYLSRQTVAIGGGTTEMARNVIGERVLGFPREYAADRGVP
FNQVRHGQRSDRS
>Mature_412_residues
TTESVAQFAARARAWLADNMPAIDRESPPPAPRDDERAWRRARELQKRLYDGGFAGICFPREYGGLGLDYEYQKAFDAES
LDYEMPLILNTPTFTICCATLLDTASEQQKEQHIAAALRGEEILVQLLSEPSGRSDLAGVLTRAERRGDRWIINGAKTWS
TSAFAADYGLCLARTNWDVPKHEGLTMFLVPINHPGITLRRITMLSGSTEFCEEFLDGVDVGDDAVVGEVNGGWAVASRQ
LYHERRAVGQGSEFASGGGSEGGHTIPVDYVSLAEKTGQADDPRVQEMAGRVLVHRAVAEQLIGHVYRSVRDGALPPAAG
TLIRLFHSETVTTDVDTALAIAGSAGVVGEPGAGLETGLRYLSRQTVAIGGGTTEMARNVIGERVLGFPREYAADRGVPF
NQVRHGQRSDRS

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=393, Percent_Identity=26.7175572519084, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI226958414, Length=364, Percent_Identity=27.1978021978022, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI4557233, Length=380, Percent_Identity=25.2631578947368, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI76496475, Length=343, Percent_Identity=27.1137026239067, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI4557235, Length=343, Percent_Identity=27.1137026239067, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI4501857, Length=371, Percent_Identity=22.911051212938, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4557231, Length=223, Percent_Identity=26.457399103139, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI187960098, Length=223, Percent_Identity=26.457399103139, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI21361497, Length=214, Percent_Identity=27.1028037383178, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87081958, Length=357, Percent_Identity=25.2100840336134, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786223, Length=349, Percent_Identity=20.6303724928367, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538396, Length=391, Percent_Identity=26.5984654731458, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17508101, Length=350, Percent_Identity=25.1428571428571, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17506239, Length=355, Percent_Identity=24.5070422535211, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17534899, Length=161, Percent_Identity=32.9192546583851, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17569725, Length=372, Percent_Identity=25.5376344086022, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17570075, Length=394, Percent_Identity=25.6345177664975, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17505929, Length=209, Percent_Identity=27.7511961722488, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71982178, Length=242, Percent_Identity=26.4462809917355, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71990804, Length=306, Percent_Identity=24.5098039215686, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17551932, Length=241, Percent_Identity=24.4813278008299, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI32563615, Length=251, Percent_Identity=27.0916334661355, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24646207, Length=371, Percent_Identity=26.6846361185984, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI21355753, Length=379, Percent_Identity=25.065963060686, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21356377, Length=387, Percent_Identity=25.8397932816537, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24660351, Length=155, Percent_Identity=31.6129032258064, Blast_Score=82, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 44832; Mature: 44701

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTESVAQFAARARAWLADNMPAIDRESPPPAPRDDERAWRRARELQKRLYDGGFAGICF
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEC
PREYGGLGLDYEYQKAFDAESLDYEMPLILNTPTFTICCATLLDTASEQQKEQHIAAALR
CHHCCCCCCCCHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEEILVQLLSEPSGRSDLAGVLTRAERRGDRWIINGAKTWSTSAFAADYGLCLARTNWDV
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHCCEEEEECCCCC
PKHEGLTMFLVPINHPGITLRRITMLSGSTEFCEEFLDGVDVGDDAVVGEVNGGWAVASR
CCCCCCEEEEEECCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCEEEECCCCHHHHHH
QLYHERRAVGQGSEFASGGGSEGGHTIPVDYVSLAEKTGQADDPRVQEMAGRVLVHRAVA
HHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
EQLIGHVYRSVRDGALPPAAGTLIRLFHSETVTTDVDTALAIAGSAGVVGEPGAGLETGL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHH
RYLSRQTVAIGGGTTEMARNVIGERVLGFPREYAADRGVPFNQVRHGQRSDRS
HHHHCCEEEECCCHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHCCCCCCCC
>Mature Secondary Structure 
TTESVAQFAARARAWLADNMPAIDRESPPPAPRDDERAWRRARELQKRLYDGGFAGICF
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEC
PREYGGLGLDYEYQKAFDAESLDYEMPLILNTPTFTICCATLLDTASEQQKEQHIAAALR
CHHCCCCCCCCHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEEILVQLLSEPSGRSDLAGVLTRAERRGDRWIINGAKTWSTSAFAADYGLCLARTNWDV
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHCCEEEEECCCCC
PKHEGLTMFLVPINHPGITLRRITMLSGSTEFCEEFLDGVDVGDDAVVGEVNGGWAVASR
CCCCCCEEEEEECCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCEEEECCCCHHHHHH
QLYHERRAVGQGSEFASGGGSEGGHTIPVDYVSLAEKTGQADDPRVQEMAGRVLVHRAVA
HHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
EQLIGHVYRSVRDGALPPAAGTLIRLFHSETVTTDVDTALAIAGSAGVVGEPGAGLETGL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHH
RYLSRQTVAIGGGTTEMARNVIGERVLGFPREYAADRGVPFNQVRHGQRSDRS
HHHHCCEEEECCCHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]