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The map label for this gene is 41408370

Identifier: 41408370

GI number: 41408370

Start: 2539089

End: 2540348

Strand: Reverse

Name: 41408370

Synonym: MAP2272c

Alternate gene names: NA

Gene position: 2540348-2539089 (Counterclockwise)

Preceding gene: 41408371

Following gene: 41408369

Centisome position: 52.6

GC content: 71.98

Gene sequence:

>1260_bases
GTGACCGCAACACCGCGCGAATTCGACATTGTCTTGTATGGGGCTACCGGCTTCGTCGGCAAGCTCACCGCCGAGTACCT
GGCCGGGGCGGCACCGGACAAGCGGGTTGCGCTGGCCGGCAGGTCCACCGAGAAGCTGCGTGCCGTCCGCGACTCGCTCG
GCGACGCCGCGCAGTCCTGGCCCGTCCTGCAGGCCGACGCCAGCTCGCCCGCCACCCTCAACGAGATGGCGGCCCGCACC
CAGGTCGTCATCACCACGGTCGGCCCGTACACCCGCTACGGGCTGCCGCTGGTGGCCGCGTGCGCGGCCGCCGGCACCGA
CTACGCCGACCTGACCGGAGAGGCGATGTTCGTCCGGGACAGCATCGACTCCTATCACAAGCAGGCCGCGGATACCGGCG
CCCGCATCGTGCACGCCTGCGGATTCGATTCGGTGCCGTCGGACCTCAGCGTGTACGCGCTGTACCGGGCGGCGCGCGAT
GACGGCGCCGGCGAGCTCGTCGACACCGACCTGGTGGTGCGTTCCTTCTCCGGCGGGGTGTCCGGCGGCACCGTCGCCTC
GATGCTCGAAGTGCTCGACACCGCATCCCGCGATCCCGAGGCCCGGCGCCAGCTCGCCGACCCCTACACGTTGAGCAGCG
ACCGCGGCGCCGAACCCGACGTCGGGCCGCAGCCCGATCTGCCGTGGCGACGGGGTCGCCAGATCGCGCCGGAACTGGCC
GGGGTGTGGACCGCGGGCTTCGTCATGGCGCCCTACAACACCCGGATCGTGCGGCGCAGCAACGCATTGCTCGACTGGGC
GTACGGCCGGTCGTTGCGTTACAGCGAAAGCATGAGCCTGGGCTCGTCGCCGCTGGCGCCGGTGGCCTCCGCGGTGGTGG
GCGGAACGGCCGCCGCGACGTTCGGGTTGGGCAGCCGCTATTTCCGGTTCCTGCCGCGCCGGCTGGTGGAGCGCATCGTG
CCCAAGCCGGGAACCGGCCCCAGCCCGGCGGCCCGCGAGCGCGGTTACTACCGGATCGAGACCTACACCACGACCACCAG
CGGCGCCCGCTACGTGGCCCGGATGGAACAGCGCGGGGACCCCGGCTACAAGGCGACCTCGGTGCTGTTGGGGGAGAGCG
GGCTGGCGCTGGCCTTCGACCGCGACAAGCTGCCGCAGCTGTACGGGGTTCTCACCCCCGCGGCCGCAATGGGCGACGCG
CTGCTGGACCGATTCCCCGGCGCGGGCGTGTTCTTGCAGGTCGACCGGCTCGCCGGGTGA

Upstream 100 bases:

>100_bases
CGCGTGGCCGGTGTGCGGCCGCCGCGGCTGATCGCAGCCATCCAAGAAGTGCCGGGCCTAGTGCCCGGCACTTCTTGGCT
CCAGGGGTAGCGTCGGGCCG

Downstream 100 bases:

>100_bases
CCCGGCTCACGGTTCGGGCACTTACATGAAGGTAAACGTCGCTCCCTAGAATTGACGGGTGACCGCCAGCCGCAGCCCCG
CCACCGACCTGCCCAAGTCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MTATPREFDIVLYGATGFVGKLTAEYLAGAAPDKRVALAGRSTEKLRAVRDSLGDAAQSWPVLQADASSPATLNEMAART
QVVITTVGPYTRYGLPLVAACAAAGTDYADLTGEAMFVRDSIDSYHKQAADTGARIVHACGFDSVPSDLSVYALYRAARD
DGAGELVDTDLVVRSFSGGVSGGTVASMLEVLDTASRDPEARRQLADPYTLSSDRGAEPDVGPQPDLPWRRGRQIAPELA
GVWTAGFVMAPYNTRIVRRSNALLDWAYGRSLRYSESMSLGSSPLAPVASAVVGGTAAATFGLGSRYFRFLPRRLVERIV
PKPGTGPSPAARERGYYRIETYTTTTSGARYVARMEQRGDPGYKATSVLLGESGLALAFDRDKLPQLYGVLTPAAAMGDA
LLDRFPGAGVFLQVDRLAG

Sequences:

>Translated_419_residues
MTATPREFDIVLYGATGFVGKLTAEYLAGAAPDKRVALAGRSTEKLRAVRDSLGDAAQSWPVLQADASSPATLNEMAART
QVVITTVGPYTRYGLPLVAACAAAGTDYADLTGEAMFVRDSIDSYHKQAADTGARIVHACGFDSVPSDLSVYALYRAARD
DGAGELVDTDLVVRSFSGGVSGGTVASMLEVLDTASRDPEARRQLADPYTLSSDRGAEPDVGPQPDLPWRRGRQIAPELA
GVWTAGFVMAPYNTRIVRRSNALLDWAYGRSLRYSESMSLGSSPLAPVASAVVGGTAAATFGLGSRYFRFLPRRLVERIV
PKPGTGPSPAARERGYYRIETYTTTTSGARYVARMEQRGDPGYKATSVLLGESGLALAFDRDKLPQLYGVLTPAAAMGDA
LLDRFPGAGVFLQVDRLAG
>Mature_418_residues
TATPREFDIVLYGATGFVGKLTAEYLAGAAPDKRVALAGRSTEKLRAVRDSLGDAAQSWPVLQADASSPATLNEMAARTQ
VVITTVGPYTRYGLPLVAACAAAGTDYADLTGEAMFVRDSIDSYHKQAADTGARIVHACGFDSVPSDLSVYALYRAARDD
GAGELVDTDLVVRSFSGGVSGGTVASMLEVLDTASRDPEARRQLADPYTLSSDRGAEPDVGPQPDLPWRRGRQIAPELAG
VWTAGFVMAPYNTRIVRRSNALLDWAYGRSLRYSESMSLGSSPLAPVASAVVGGTAAATFGLGSRYFRFLPRRLVERIVP
KPGTGPSPAARERGYYRIETYTTTTSGARYVARMEQRGDPGYKATSVLLGESGLALAFDRDKLPQLYGVLTPAAAMGDAL
LDRFPGAGVFLQVDRLAG

Specific function: Unknown

COG id: COG3268

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the saccharopine dehydrogenase family. Enoyl reductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI55770836, Length=450, Percent_Identity=28.2222222222222, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI32567112, Length=201, Percent_Identity=34.3283582089552, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17560066, Length=201, Percent_Identity=34.3283582089552, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71991033, Length=171, Percent_Identity=30.9941520467836, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24646278, Length=439, Percent_Identity=26.4236902050114, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24644140, Length=425, Percent_Identity=28.2352941176471, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24644142, Length=425, Percent_Identity=28.2352941176471, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI21356081, Length=425, Percent_Identity=28.2352941176471, Blast_Score=116, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR005097 [H]

Pfam domain/function: PF03435 Saccharop_dh [H]

EC number: NA

Molecular weight: Translated: 44524; Mature: 44392

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATPREFDIVLYGATGFVGKLTAEYLAGAAPDKRVALAGRSTEKLRAVRDSLGDAAQSW
CCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCC
PVLQADASSPATLNEMAARTQVVITTVGPYTRYGLPLVAACAAAGTDYADLTGEAMFVRD
CEEEECCCCCCHHHHHHHCEEEEEEECCCHHHHCHHHHHHHHHCCCCHHHCCCCEEEEHH
SIDSYHKQAADTGARIVHACGFDSVPSDLSVYALYRAARDDGAGELVDTDLVVRSFSGGV
HHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCC
SGGTVASMLEVLDTASRDPEARRQLADPYTLSSDRGAEPDVGPQPDLPWRRGRQIAPELA
CCHHHHHHHHHHHHCCCCHHHHHHHCCCCEECCCCCCCCCCCCCCCCCHHCCCCCCHHHH
GVWTAGFVMAPYNTRIVRRSNALLDWAYGRSLRYSESMSLGSSPLAPVASAVVGGTAAAT
HHHHHCEEECCCCCEEEECCCCEEEECCCCCCCCHHHCCCCCCCHHHHHHHHHCCHHHHH
FGLGSRYFRFLPRRLVERIVPKPGTGPSPAARERGYYRIETYTTTTSGARYVARMEQRGD
HCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCEEEEEEEECCCCHHHHHHHHHCCC
PGYKATSVLLGESGLALAFDRDKLPQLYGVLTPAAAMGDALLDRFPGAGVFLQVDRLAG
CCCCEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
>Mature Secondary Structure 
TATPREFDIVLYGATGFVGKLTAEYLAGAAPDKRVALAGRSTEKLRAVRDSLGDAAQSW
CCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCC
PVLQADASSPATLNEMAARTQVVITTVGPYTRYGLPLVAACAAAGTDYADLTGEAMFVRD
CEEEECCCCCCHHHHHHHCEEEEEEECCCHHHHCHHHHHHHHHCCCCHHHCCCCEEEEHH
SIDSYHKQAADTGARIVHACGFDSVPSDLSVYALYRAARDDGAGELVDTDLVVRSFSGGV
HHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCC
SGGTVASMLEVLDTASRDPEARRQLADPYTLSSDRGAEPDVGPQPDLPWRRGRQIAPELA
CCHHHHHHHHHHHHCCCCHHHHHHHCCCCEECCCCCCCCCCCCCCCCCHHCCCCCCHHHH
GVWTAGFVMAPYNTRIVRRSNALLDWAYGRSLRYSESMSLGSSPLAPVASAVVGGTAAAT
HHHHHCEEECCCCCEEEECCCCEEEECCCCCCCCHHHCCCCCCCHHHHHHHHHCCHHHHH
FGLGSRYFRFLPRRLVERIVPKPGTGPSPAARERGYYRIETYTTTTSGARYVARMEQRGD
HCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCEEEEEEEECCCCHHHHHHHHHCCC
PGYKATSVLLGESGLALAFDRDKLPQLYGVLTPAAAMGDALLDRFPGAGVFLQVDRLAG
CCCCEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]