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The map label for this gene is bioI [H]

Identifier: 41408281

GI number: 41408281

Start: 2424796

End: 2426046

Strand: Reverse

Name: bioI [H]

Synonym: MAP2183c

Alternate gene names: 41408281

Gene position: 2426046-2424796 (Counterclockwise)

Preceding gene: 41408282

Following gene: 41408280

Centisome position: 50.23

GC content: 67.15

Gene sequence:

>1251_bases
ATGACCGCTCCCGCACTGGATCGCGACCGACTGCGCGAGCTGTTCGACCTGCGCAGCTCCTACAACGCTTGGGCCGGCGG
CGCATACGAGGACGACCCGTACCCGGTGTGGCACCGGCTGCGCGAGAAGGGGCCGGTGCTGCCCGGCGTCCTGCACGAGC
TGACCGGCAGCACCGACACGATGTTCTTCCACGGGCTGCCGTACCCGGACTGCCCGCATTTCACGGTGTTCGACTACGAC
TCGTGCATGATCGCTTACCGCAATCCGGAGGTGTTCGCCTCGTCCCCGGAGCCCGTCGACCTCGAGCATGGCCCGCTGGG
CCTGACCAACAGCATGCTGTCGATGAACGGCGAACAGCACAAGCGGTATCGCGCGTTGGTCCAGCCGTCGTTCCTGCCGG
CGAATGGCAAGTGGTGGATTGACAATTGGATCTCCGAGACCGTCGACCTGCTCATCGACGGACTGGTTCACGAGGGGCGC
GCCGAACTCAACGTCGACTTCTGCGCGGCCATCCCGGTGCTGACCATCACCGGCAGCTTCGGCGTGCCCGTCGAGCAGGC
CCTCGACATCCGCGAGGCGCTGGCGCGGGATCCGCAGAAGGTGGTCGACCTGCTCAAGCCGGTGATCGCCGCCCGCCCCG
AGGAGCCGCGCGACGACCTGATCAGCGTCCTCGTGCAGGCCGAACTCACCGACGAGGACGGCGCCAAGGACCGGCTCACC
GATCGCGAAATCGATTCCTTCGTGCTGCTGTTGCTCGGCGCGGGCTCGGGCACCACCTGGAAGCAGATGGGCACCACGCT
GACGACGCTGTTGCAGCGTCCCGAACTCCTCGAGGCGGTGCGCGCGGACCGTTCGCTTTTGCGGCCGGCGATCGAGGAGG
CGATCCGGTGGATGCCGACCGATCCGATGTTCTCCCGCTGGGTGATGGCCGATACCGAGCTGGCCGGCGTGTCGATCCCC
GCCGGGTCTGTCGTGCACCTCGCGCTCGGGGCGGCCAACCGGGATCCCGCCCGCTGGGACCGTCCCGACGAATACGACAT
CACCCGAAAGTTCAAGCCGTCGTTGGGTTTCGGGCAGGGTTCACACATCTGCCTCGGCATGCACGTAGCCCGCGCTGAGA
TGACTATAGCGATCTCGGCGCTGCTCGACCGGCTGCCCAACCTGCGGCTGGATCCCGACGCCGAACCGCCCCGCTTCGTC
GGAATGTACGAGCGCGGGGCGACCGCCATACCGGTGGTGTTCGATGTCTGA

Upstream 100 bases:

>100_bases
CGGCCGAGGACTGCGCCGAGGCGGCGCTGTATCTGGTCTCGGACGCGGCGCGCAACGTCACCGGGGTGGCGCTGCCGGTC
GACGGCGGGTTCGTGGCGAA

Downstream 100 bases:

>100_bases
ACCCGGCTACACACCGCCCGACCTGATGCTGGTCGGCGACGACCACGTGCGCGCATACCGCGAAACCGGCGGCGAGACCG
GCTATCTGTGGAACGGCGTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MTAPALDRDRLRELFDLRSSYNAWAGGAYEDDPYPVWHRLREKGPVLPGVLHELTGSTDTMFFHGLPYPDCPHFTVFDYD
SCMIAYRNPEVFASSPEPVDLEHGPLGLTNSMLSMNGEQHKRYRALVQPSFLPANGKWWIDNWISETVDLLIDGLVHEGR
AELNVDFCAAIPVLTITGSFGVPVEQALDIREALARDPQKVVDLLKPVIAARPEEPRDDLISVLVQAELTDEDGAKDRLT
DREIDSFVLLLLGAGSGTTWKQMGTTLTTLLQRPELLEAVRADRSLLRPAIEEAIRWMPTDPMFSRWVMADTELAGVSIP
AGSVVHLALGAANRDPARWDRPDEYDITRKFKPSLGFGQGSHICLGMHVARAEMTIAISALLDRLPNLRLDPDAEPPRFV
GMYERGATAIPVVFDV

Sequences:

>Translated_416_residues
MTAPALDRDRLRELFDLRSSYNAWAGGAYEDDPYPVWHRLREKGPVLPGVLHELTGSTDTMFFHGLPYPDCPHFTVFDYD
SCMIAYRNPEVFASSPEPVDLEHGPLGLTNSMLSMNGEQHKRYRALVQPSFLPANGKWWIDNWISETVDLLIDGLVHEGR
AELNVDFCAAIPVLTITGSFGVPVEQALDIREALARDPQKVVDLLKPVIAARPEEPRDDLISVLVQAELTDEDGAKDRLT
DREIDSFVLLLLGAGSGTTWKQMGTTLTTLLQRPELLEAVRADRSLLRPAIEEAIRWMPTDPMFSRWVMADTELAGVSIP
AGSVVHLALGAANRDPARWDRPDEYDITRKFKPSLGFGQGSHICLGMHVARAEMTIAISALLDRLPNLRLDPDAEPPRFV
GMYERGATAIPVVFDV
>Mature_415_residues
TAPALDRDRLRELFDLRSSYNAWAGGAYEDDPYPVWHRLREKGPVLPGVLHELTGSTDTMFFHGLPYPDCPHFTVFDYDS
CMIAYRNPEVFASSPEPVDLEHGPLGLTNSMLSMNGEQHKRYRALVQPSFLPANGKWWIDNWISETVDLLIDGLVHEGRA
ELNVDFCAAIPVLTITGSFGVPVEQALDIREALARDPQKVVDLLKPVIAARPEEPRDDLISVLVQAELTDEDGAKDRLTD
REIDSFVLLLLGAGSGTTWKQMGTTLTTLLQRPELLEAVRADRSLLRPAIEEAIRWMPTDPMFSRWVMADTELAGVSIPA
GSVVHLALGAANRDPARWDRPDEYDITRKFKPSLGFGQGSHICLGMHVARAEMTIAISALLDRLPNLRLDPDAEPPRFVG
MYERGATAIPVVFDV

Specific function: Catalyzes the C-C bond cleavage of fatty acid linked to acyl carrier protein (ACP) to generate pimelic acid for biotin biosynthesis. It has high affinity for long-chain fatty acids with the greatest affinity for myristic acid [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

Organism=Homo sapiens, GI4503231, Length=365, Percent_Identity=23.2876712328767, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 46303; Mature: 46172

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPALDRDRLRELFDLRSSYNAWAGGAYEDDPYPVWHRLREKGPVLPGVLHELTGSTDT
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCE
MFFHGLPYPDCPHFTVFDYDSCMIAYRNPEVFASSPEPVDLEHGPLGLTNSMLSMNGEQH
EEECCCCCCCCCCEEEEECCCEEEEECCCCEECCCCCCCCCCCCCCCCCHHHHHCCCHHH
KRYRALVQPSFLPANGKWWIDNWISETVDLLIDGLVHEGRAELNVDFCAAIPVLTITGSF
HHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCEEEEECCC
GVPVEQALDIREALARDPQKVVDLLKPVIAARPEEPRDDLISVLVQAELTDEDGAKDRLT
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHCC
DREIDSFVLLLLGAGSGTTWKQMGTTLTTLLQRPELLEAVRADRSLLRPAIEEAIRWMPT
HHHHHHEEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
DPMFSRWVMADTELAGVSIPAGSVVHLALGAANRDPARWDRPDEYDITRKFKPSLGFGQG
CHHHHHHEECCCCCCCEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SHICLGMHVARAEMTIAISALLDRLPNLRLDPDAEPPRFVGMYERGATAIPVVFDV
CEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHCCCEEEEEEEEC
>Mature Secondary Structure 
TAPALDRDRLRELFDLRSSYNAWAGGAYEDDPYPVWHRLREKGPVLPGVLHELTGSTDT
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCE
MFFHGLPYPDCPHFTVFDYDSCMIAYRNPEVFASSPEPVDLEHGPLGLTNSMLSMNGEQH
EEECCCCCCCCCCEEEEECCCEEEEECCCCEECCCCCCCCCCCCCCCCCHHHHHCCCHHH
KRYRALVQPSFLPANGKWWIDNWISETVDLLIDGLVHEGRAELNVDFCAAIPVLTITGSF
HHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCEEEEECCC
GVPVEQALDIREALARDPQKVVDLLKPVIAARPEEPRDDLISVLVQAELTDEDGAKDRLT
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHCC
DREIDSFVLLLLGAGSGTTWKQMGTTLTTLLQRPELLEAVRADRSLLRPAIEEAIRWMPT
HHHHHHEEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
DPMFSRWVMADTELAGVSIPAGSVVHLALGAANRDPARWDRPDEYDITRKFKPSLGFGQG
CHHHHHHEECCCCCCCEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SHICLGMHVARAEMTIAISALLDRLPNLRLDPDAEPPRFVGMYERGATAIPVVFDV
CEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8763940; 9387221; 9384377 [H]