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The map label for this gene is mbtB [H]

Identifier: 41408274

GI number: 41408274

Start: 2417175

End: 2417939

Strand: Reverse

Name: mbtB [H]

Synonym: MAP2176c

Alternate gene names: 41408274

Gene position: 2417939-2417175 (Counterclockwise)

Preceding gene: 41408275

Following gene: 41408273

Centisome position: 50.06

GC content: 70.07

Gene sequence:

>765_bases
ATGACATTGAATAACATCGCTACCATGCCCTCCGCCTTCCCGTCCTGGATCAAGCTGGCCCCGGGCCGCGGCGGCCCGGC
GTCCGGGACGGGCGCCACCATAGTGTTCCCGCATGCCGGCGCGGCCGCCGCGAGCTATCGGGTGCTCGCGGCGGCGTTGG
CCGCCGGCGCCGACACCTACGTCGTGCAGTACCCGCAGCGGGCCGAGCGCCTCGGCGACCCCGCCCACGAGAGCGTGCAT
GATCTGGCCGCCGGCCTGTTCCGGGCCGCGCCCTGGCCCGGAGTGGCGCCGCTGACGTTGTTCGGGTACAGCATGGGCGG
CGTCGTCGCCTTCGAATTCGCCCGCGTCGCCGAGGCGAACGGAACCCCGGTGCGCAAGCTGTGGGTGTCGGCCGGCCCGC
CGCCCTGCGTGGTCGGCGACATGCCCGAACTGCCGACCACCCACGACGGGCTGCTCGCCGACATCGCGGATTTGGGCGGC
ACCGACCCCGAATTGCTTGCCGACGAAGAATTCTCCGAACTGCTGACCACCGCCGTGCGCGCCGACTACCAAGCCTTCAA
CGGGTACGACCCCAGCCCCGACGTCCGCATCGGCGCGGACATCCATGTGCTGGGCGGTCATCATGACCACCGCATCGCAA
CCGGCGTGCTCCGGCAATGGGAGAGGCACACCGCCGGATCCTTTGCCATGTCGCTGTACGACGGCGGGCACTTCTACCTC
TACGACCACGTCGAAACGGTCGCGGCGCAGGTGAATGCCGGGTGA

Upstream 100 bases:

>100_bases
GGCTCGACCACGTCGCCGAGTTGTATCTGGAGGTGATCGGCATGGATGCTGAATCGGTGCTGACGGCTACCCGGCAAACT
ACGAAATCGTAACCGGTGCA

Downstream 100 bases:

>100_bases
CGCCGATGTCTGAGAACGGGTTCGATGCCGCCGGCATCGACCCGGTGGTGATCGTGGGGATGGGTGTCGAGGCGCCCGGC
GGCATCGAGACCGCCGAAGA

Product: hypothetical protein

Products: NA

Alternate protein names: Mycobactin synthetase protein B [H]

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTLNNIATMPSAFPSWIKLAPGRGGPASGTGATIVFPHAGAAAASYRVLAAALAAGADTYVVQYPQRAERLGDPAHESVH
DLAAGLFRAAPWPGVAPLTLFGYSMGGVVAFEFARVAEANGTPVRKLWVSAGPPPCVVGDMPELPTTHDGLLADIADLGG
TDPELLADEEFSELLTTAVRADYQAFNGYDPSPDVRIGADIHVLGGHHDHRIATGVLRQWERHTAGSFAMSLYDGGHFYL
YDHVETVAAQVNAG

Sequences:

>Translated_254_residues
MTLNNIATMPSAFPSWIKLAPGRGGPASGTGATIVFPHAGAAAASYRVLAAALAAGADTYVVQYPQRAERLGDPAHESVH
DLAAGLFRAAPWPGVAPLTLFGYSMGGVVAFEFARVAEANGTPVRKLWVSAGPPPCVVGDMPELPTTHDGLLADIADLGG
TDPELLADEEFSELLTTAVRADYQAFNGYDPSPDVRIGADIHVLGGHHDHRIATGVLRQWERHTAGSFAMSLYDGGHFYL
YDHVETVAAQVNAG
>Mature_253_residues
TLNNIATMPSAFPSWIKLAPGRGGPASGTGATIVFPHAGAAAASYRVLAAALAAGADTYVVQYPQRAERLGDPAHESVHD
LAAGLFRAAPWPGVAPLTLFGYSMGGVVAFEFARVAEANGTPVRKLWVSAGPPPCVVGDMPELPTTHDGLLADIADLGGT
DPELLADEEFSELLTTAVRADYQAFNGYDPSPDVRIGADIHVLGGHHDHRIATGVLRQWERHTAGSFAMSLYDGGHFYLY
DHVETVAAQVNAG

Specific function: Involved in the initial steps of the mycobactin biosynthetic pathway. Putatively couples activated salicylic acid with serine or threonine and cyclizes this precursor to the hydroxyphenyloxazoline ring system present in this class of siderophores [H]

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 acyl carrier domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR013624
- InterPro:   IPR006163
- InterPro:   IPR006162
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF08415 NRPS; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 26670; Mature: 26539

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLNNIATMPSAFPSWIKLAPGRGGPASGTGATIVFPHAGAAAASYRVLAAALAAGADTY
CCCCCHHCCCCCCCHHEEECCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEE
VVQYPQRAERLGDPAHESVHDLAAGLFRAAPWPGVAPLTLFGYSMGGVVAFEFARVAEAN
EEECCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCC
GTPVRKLWVSAGPPPCVVGDMPELPTTHDGLLADIADLGGTDPELLADEEFSELLTTAVR
CCCEEEEEECCCCCCEEECCCCCCCCCCCHHHHHHHHCCCCCHHHHCHHHHHHHHHHHHH
ADYQAFNGYDPSPDVRIGADIHVLGGHHDHRIATGVLRQWERHTAGSFAMSLYDGGHFYL
HHHHHHCCCCCCCCEEECCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCEEEE
YDHVETVAAQVNAG
EHHHHHHHHHCCCC
>Mature Secondary Structure 
TLNNIATMPSAFPSWIKLAPGRGGPASGTGATIVFPHAGAAAASYRVLAAALAAGADTY
CCCCHHCCCCCCCHHEEECCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEE
VVQYPQRAERLGDPAHESVHDLAAGLFRAAPWPGVAPLTLFGYSMGGVVAFEFARVAEAN
EEECCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCC
GTPVRKLWVSAGPPPCVVGDMPELPTTHDGLLADIADLGGTDPELLADEEFSELLTTAVR
CCCEEEEEECCCCCCEEECCCCCCCCCCCHHHHHHHHCCCCCHHHHCHHHHHHHHHHHHH
ADYQAFNGYDPSPDVRIGADIHVLGGHHDHRIATGVLRQWERHTAGSFAMSLYDGGHFYL
HHHHHHCCCCCCCCEEECCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCEEEE
YDHVETVAAQVNAG
EHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]