BacMap

Definition	Mycobacterium avium subsp. paratuberculosis K-10, complete genome.
Accession	NC_002944
Length	4,829,781

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The map label for this gene is dnaJ2

Identifier: 41408260

GI number: 41408260

Start: 2394504

End: 2395649

Strand: Reverse

Name: dnaJ2

Synonym: MAP2162c

Alternate gene names: 41408260

Gene position: 2395649-2394504 (Counterclockwise)

Preceding gene: 41408261

Following gene: 41408259

Centisome position: 49.6

GC content: 72.69

Gene sequence:

>1146_bases
GTGGCACGCGACTATTACGGGCTGCTCGGCGTGAGCCGAGGCGCCAGCGATGCGGAGATCAAACGCGCGTACCGCAAGCT
GGCGCGCGAACTGCATCCCGACGTCAACCCCGACGAGGCCGCGCAGGCGAAATTCAAGGAGATCAGCGTCGCCTACGAGG
TGCTCAGCGACCCGGAGAAACGGCGGATCGTCGACCTGGGCGGTGATCCGCTGGAGGGGGCGGCCGCGGCGGGCGGCGGC
TTCGGAGGGTTCGGCGGCCTCGGCGATGTGTTCGAGGCCTTTTTCGGGGGCGGCTTCGGCGGCGGCACCACCTCCCGCGG
CCCGATCGGGCGGGTCCGGCCGGGCTCGGATTCGCTGCTGCGGATGCGGCTCGACCTCGAGGAGTGCGCCACCGGGGTGA
CCAAGCAGGTCACCGTCGACACCGCCGTGCTGTGCGACCGCTGCCACGGCAAGGGCACCAACGGCGACTCCGCCCCGGTG
CCATGCGACACCTGCGGCGGCCGCGGCGAGGTGCAGACGGTGCAGCGCTCGTTGCTCGGCCAGGTGATGACGTCCCGGCC
GTGCCCGACCTGCCGCGGCGTCGGCGTCGTCATCCCCGACCCGTGCCACCAGTGCATGGGCGACGGCCGGGTGCGGGCCC
GCCGCGAGATCAGCGTCAAGATCCCCGCCGGGGTGGGTGACGGCATGCGGGTGCGGCTGGCCGCCCAGGGCGAGGTGGGT
CCCGGCGGCGGCCCGGCCGGTGACCTCTACGTCGAGGTGCACGAACAGCCGCATGATGTCTTCGTCCGCGAGGGCGACGA
CCTGCACTGCACGGTGTCGGTGCCGATGGTCGACGCGGCGCTGGGCGCCACCGTCACCGTCGACGCCATCCTGGACGGCG
TCAGCGAAATCACCATTCCGCCCGGCACCCAACCGGGTTCGGTCATCACGCTGCGCGGCCACGGCATGCCGCACCTGCGG
TCGGGCACCCGCGGCGATCTGCACGTGCACGTCGAGGTGGTGGTGCCCAGCCGGCTGGACGCCCGCGATACCGAGCTGCT
GCGCGAATTCAAGGGCCGCCGTGGCCGCGACGTCCCCGAGGTCCGCTCCACCCACGCCGGCGGCGGATTGTTCAGCCGGC
TGCGCGAGACCTTCACCGGGCGCTAG

Upstream 100 bases:

>100_bases
TGCGGTTGCCATGTATATCGGCGAAGTCCTGGGTGCTCGATGAGCGCGCACCCGCACGGTGGGTAGGCGCGGAAAAGACC
AGGTATTAGGAGAGGCAAGC

Downstream 100 bases:

>100_bases
CCCGACGCCGCGCGGGCCCGCCCATGGTCGCGACGCTGTTCTACACCGACGAGCTGCCCGACGCCGGCTCGCTGGCCGTG
CTGGGCGGCGACGAGGGGTT

Product: chaperone protein DnaJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MARDYYGLLGVSRGASDAEIKRAYRKLARELHPDVNPDEAAQAKFKEISVAYEVLSDPEKRRIVDLGGDPLEGAAAAGGG
FGGFGGLGDVFEAFFGGGFGGGTTSRGPIGRVRPGSDSLLRMRLDLEECATGVTKQVTVDTAVLCDRCHGKGTNGDSAPV
PCDTCGGRGEVQTVQRSLLGQVMTSRPCPTCRGVGVVIPDPCHQCMGDGRVRARREISVKIPAGVGDGMRVRLAAQGEVG
PGGGPAGDLYVEVHEQPHDVFVREGDDLHCTVSVPMVDAALGATVTVDAILDGVSEITIPPGTQPGSVITLRGHGMPHLR
SGTRGDLHVHVEVVVPSRLDARDTELLREFKGRRGRDVPEVRSTHAGGGLFSRLRETFTGR

Sequences:

>Translated_381_residues
MARDYYGLLGVSRGASDAEIKRAYRKLARELHPDVNPDEAAQAKFKEISVAYEVLSDPEKRRIVDLGGDPLEGAAAAGGG
FGGFGGLGDVFEAFFGGGFGGGTTSRGPIGRVRPGSDSLLRMRLDLEECATGVTKQVTVDTAVLCDRCHGKGTNGDSAPV
PCDTCGGRGEVQTVQRSLLGQVMTSRPCPTCRGVGVVIPDPCHQCMGDGRVRARREISVKIPAGVGDGMRVRLAAQGEVG
PGGGPAGDLYVEVHEQPHDVFVREGDDLHCTVSVPMVDAALGATVTVDAILDGVSEITIPPGTQPGSVITLRGHGMPHLR
SGTRGDLHVHVEVVVPSRLDARDTELLREFKGRRGRDVPEVRSTHAGGGLFSRLRETFTGR
>Mature_380_residues
ARDYYGLLGVSRGASDAEIKRAYRKLARELHPDVNPDEAAQAKFKEISVAYEVLSDPEKRRIVDLGGDPLEGAAAAGGGF
GGFGGLGDVFEAFFGGGFGGGTTSRGPIGRVRPGSDSLLRMRLDLEECATGVTKQVTVDTAVLCDRCHGKGTNGDSAPVP
CDTCGGRGEVQTVQRSLLGQVMTSRPCPTCRGVGVVIPDPCHQCMGDGRVRARREISVKIPAGVGDGMRVRLAAQGEVGP
GGGPAGDLYVEVHEQPHDVFVREGDDLHCTVSVPMVDAALGATVTVDAILDGVSEITIPPGTQPGSVITLRGHGMPHLRS
GTRGDLHVHVEVVVPSRLDARDTELLREFKGRRGRDVPEVRSTHAGGGLFSRLRETFTGR

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG0484

COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI205360838, Length=352, Percent_Identity=33.8068181818182, Blast_Score=188, Evalue=6e-48,
Organism=Homo sapiens, GI205360840, Length=352, Percent_Identity=33.8068181818182, Blast_Score=188, Evalue=7e-48,
Organism=Homo sapiens, GI194328758, Length=342, Percent_Identity=34.2105263157895, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI194328760, Length=342, Percent_Identity=34.2105263157895, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI5031741, Length=343, Percent_Identity=37.0262390670554, Blast_Score=168, Evalue=7e-42,
Organism=Homo sapiens, GI4504511, Length=341, Percent_Identity=34.0175953079179, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI7706495, Length=342, Percent_Identity=31.5789473684211, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI194328762, Length=307, Percent_Identity=30.6188925081433, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI5453690, Length=359, Percent_Identity=26.7409470752089, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI194306642, Length=118, Percent_Identity=46.6101694915254, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI194306640, Length=118, Percent_Identity=46.6101694915254, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI6631085, Length=188, Percent_Identity=34.5744680851064, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI72534740, Length=117, Percent_Identity=40.1709401709402, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI201862587, Length=69, Percent_Identity=53.6231884057971, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI201862518, Length=69, Percent_Identity=53.6231884057971, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI56549115, Length=69, Percent_Identity=53.6231884057971, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI47777312, Length=132, Percent_Identity=43.1818181818182, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI56687498, Length=66, Percent_Identity=60.6060606060606, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI27151736, Length=107, Percent_Identity=46.7289719626168, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI88501736, Length=107, Percent_Identity=46.7289719626168, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI23503241, Length=104, Percent_Identity=45.1923076923077, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI39204547, Length=172, Percent_Identity=34.3023255813954, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI4885495, Length=64, Percent_Identity=59.375, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI17388799, Length=104, Percent_Identity=49.0384615384615, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI22749377, Length=108, Percent_Identity=40.7407407407407, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI21553335, Length=101, Percent_Identity=45.5445544554455, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI5453980, Length=102, Percent_Identity=44.1176470588235, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI9558755, Length=117, Percent_Identity=38.4615384615385, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI68077168, Length=81, Percent_Identity=49.3827160493827, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI68077166, Length=81, Percent_Identity=49.3827160493827, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI29126218, Length=64, Percent_Identity=54.6875, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI21361912, Length=62, Percent_Identity=48.3870967741936, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1786197, Length=351, Percent_Identity=44.1595441595442, Blast_Score=261, Evalue=4e-71,
Organism=Escherichia coli, GI1787235, Length=357, Percent_Identity=28.5714285714286, Blast_Score=134, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI17553096, Length=350, Percent_Identity=34.8571428571429, Blast_Score=180, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI17553098, Length=350, Percent_Identity=34.8571428571429, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17507263, Length=346, Percent_Identity=37.5722543352601, Blast_Score=154, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI17563890, Length=361, Percent_Identity=32.6869806094183, Blast_Score=131, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI212645553, Length=357, Percent_Identity=31.9327731092437, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17554644, Length=94, Percent_Identity=52.1276595744681, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17534355, Length=192, Percent_Identity=32.2916666666667, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI115532476, Length=65, Percent_Identity=56.9230769230769, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI86563276, Length=103, Percent_Identity=40.7766990291262, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17551190, Length=77, Percent_Identity=53.2467532467532, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17510335, Length=77, Percent_Identity=50.6493506493506, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17538236, Length=116, Percent_Identity=38.7931034482759, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324265, Length=341, Percent_Identity=36.0703812316716, Blast_Score=165, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6323870, Length=368, Percent_Identity=31.25, Blast_Score=140, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6323119, Length=380, Percent_Identity=28.9473684210526, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6321094, Length=381, Percent_Identity=30.4461942257218, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6324252, Length=421, Percent_Identity=24.9406175771971, Blast_Score=96, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6323813, Length=106, Percent_Identity=46.2264150943396, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324103, Length=63, Percent_Identity=58.7301587301587, Blast_Score=73, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6320888, Length=98, Percent_Identity=44.8979591836735, Blast_Score=66, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322194, Length=95, Percent_Identity=43.1578947368421, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324321, Length=69, Percent_Identity=50.7246376811594, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI45552813, Length=373, Percent_Identity=31.9034852546917, Blast_Score=168, Evalue=7e-42,
Organism=Drosophila melanogaster, GI45549272, Length=373, Percent_Identity=31.9034852546917, Blast_Score=167, Evalue=8e-42,
Organism=Drosophila melanogaster, GI45552811, Length=373, Percent_Identity=31.9034852546917, Blast_Score=167, Evalue=9e-42,
Organism=Drosophila melanogaster, GI20129487, Length=341, Percent_Identity=35.4838709677419, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24584014, Length=341, Percent_Identity=35.4838709677419, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24646562, Length=346, Percent_Identity=33.5260115606936, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24646560, Length=346, Percent_Identity=33.5260115606936, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24646558, Length=346, Percent_Identity=33.5260115606936, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24646556, Length=346, Percent_Identity=33.5260115606936, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI21357547, Length=346, Percent_Identity=33.5260115606936, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI19920464, Length=351, Percent_Identity=28.4900284900285, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28574949, Length=376, Percent_Identity=27.3936170212766, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI18858081, Length=369, Percent_Identity=28.7262872628726, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24658562, Length=124, Percent_Identity=44.3548387096774, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24658555, Length=124, Percent_Identity=44.3548387096774, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24654066, Length=67, Percent_Identity=59.7014925373134, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24654070, Length=67, Percent_Identity=59.7014925373134, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24654068, Length=67, Percent_Identity=59.7014925373134, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24654072, Length=67, Percent_Identity=59.7014925373134, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21355911, Length=84, Percent_Identity=53.5714285714286, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI161077138, Length=64, Percent_Identity=60.9375, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI85726398, Length=116, Percent_Identity=41.3793103448276, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24668492, Length=69, Percent_Identity=44.9275362318841, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21358273, Length=116, Percent_Identity=37.0689655172414, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24762799, Length=99, Percent_Identity=40.4040404040404, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17648033, Length=109, Percent_Identity=39.4495412844037, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24584630, Length=109, Percent_Identity=38.5321100917431, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 40148; Mature: 40017

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARDYYGLLGVSRGASDAEIKRAYRKLARELHPDVNPDEAAQAKFKEISVAYEVLSDPEK
CCCCCEEHEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
RRIVDLGGDPLEGAAAAGGGFGGFGGLGDVFEAFFGGGFGGGTTSRGPIGRVRPGSDSLL
CEEEECCCCCCCCCHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEE
RMRLDLEECATGVTKQVTVDTAVLCDRCHGKGTNGDSAPVPCDTCGGRGEVQTVQRSLLG
EEEECHHHHCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
QVMTSRPCPTCRGVGVVIPDPCHQCMGDGRVRARREISVKIPAGVGDGMRVRLAAQGEVG
HHHHCCCCCCCCCCEEECCCHHHHHCCCCCEEEEEEEEEEECCCCCCCCEEEEEECCCCC
PGGGPAGDLYVEVHEQPHDVFVREGDDLHCTVSVPMVDAALGATVTVDAILDGVSEITIP
CCCCCCCCEEEEEECCCCEEEEECCCCEEEEEECCHHHHHHCCEEEHHHHHCCHHHEEEC
PGTQPGSVITLRGHGMPHLRSGTRGDLHVHVEVVVPSRLDARDTELLREFKGRRGRDVPE
CCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCHH
VRSTHAGGGLFSRLRETFTGR
HHHCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
ARDYYGLLGVSRGASDAEIKRAYRKLARELHPDVNPDEAAQAKFKEISVAYEVLSDPEK
CCCCEEHEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
RRIVDLGGDPLEGAAAAGGGFGGFGGLGDVFEAFFGGGFGGGTTSRGPIGRVRPGSDSLL
CEEEECCCCCCCCCHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEE
RMRLDLEECATGVTKQVTVDTAVLCDRCHGKGTNGDSAPVPCDTCGGRGEVQTVQRSLLG
EEEECHHHHCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
QVMTSRPCPTCRGVGVVIPDPCHQCMGDGRVRARREISVKIPAGVGDGMRVRLAAQGEVG
HHHHCCCCCCCCCCEEECCCHHHHHCCCCCEEEEEEEEEEECCCCCCCCEEEEEECCCCC
PGGGPAGDLYVEVHEQPHDVFVREGDDLHCTVSVPMVDAALGATVTVDAILDGVSEITIP
CCCCCCCCEEEEEECCCCEEEEECCCCEEEEEECCHHHHHHCCEEEHHHHHCCHHHEEEC
PGTQPGSVITLRGHGMPHLRSGTRGDLHVHVEVVVPSRLDARDTELLREFKGRRGRDVPE
CCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCHH
VRSTHAGGGLFSRLRETFTGR
HHHCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]