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The map label for this gene is hrcA

Identifier: 41408261

GI number: 41408261

Start: 2395707

End: 2396738

Strand: Reverse

Name: hrcA

Synonym: MAP2163c

Alternate gene names: 41408261

Gene position: 2396738-2395707 (Counterclockwise)

Preceding gene: 41408265

Following gene: 41408260

Centisome position: 49.62

GC content: 68.31

Gene sequence:

>1032_bases
GTGGGGAGTGCCGATGAGCGTCGCTTCGAGGTGCTGCGCGCCATCGTCGCCGACTTCGTCGCCACCAAGGAGCCGATCGG
TTCCAAGACCTTGGTGGAGCGTCATAACCTGGGCGTGTCGTCGGCTACCGTCCGCAACGACATGGCGGTGCTGGAGGCCG
AGGGCTACATCACCCAGCCGCACACCAGCTCCGGGCGGGTCCCCACCGAGAAGGGCTACCGCGAATTCGTCGACCGGCTC
GACGACGTCAAGCCGCTGTCGGCGGCCGAACGGCGCGCGATCCAGAACTTCCTGGAATCGGGTGTCGACCTCGACGACGT
GCTGCGCCGCGCGGTGCGGCTGCTGGCGCAGCTGACCCGGCAGGTGGCCATCGTGCAGTACCCGACGTTGTCGTCGTCCA
CCGTGCGGCACCTCGAGGTGATCGCCCTGACCCCGGCGCGGCTGCTGATGGTCGTCATCACCGACTCCGGCCGGGTGGAT
CAGCGCATCGTCGAACTCGGCGACGTCATCGACGACCACGAGCTGTCCCGGCTGCGCGAGATGCTCGGGCAGGCATTGGT
CGGCAAGAAGCTGTCCGCCGCGTCGGTCGCGGTGGCCGACCTCGCCGAGCAGCTGCGCAGCCCCGACGGCCTGGGTGACG
CGGTGGGCCGGTCGGCGACGGTGTTGCTGGAGTCGCTGGTCGAACACAGCGAGGAACGCCTGCTGATGGGCGGTACCGCC
AACCTGACCCGCAACGCCGCCGATTTCGGCGGCTCGTTGCGTTCCATCCTGGAGGCGCTCGAGGAGCAGGTCGTGGTGCT
GCGGTTGCTGGCCGCCCAGCAGGAGGCCGGTAAGGTGACGGTGCGCATCGGCCACGAGACGGCCGCCGAGCAGATGGTGG
GCACCTCGATGGTCACCACCGCCTACGGCACCTCCGACACCGTTTACGGGGGAATGGGTGTGCTGGGGCCCACCCGGATG
GACTATCCGGGAACTATCGCCAGCGTTGCTGCGGTTGCCATGTATATCGGCGAAGTCCTGGGTGCTCGATGA

Upstream 100 bases:

>100_bases
GGGAGCTTTTGCGTCTGCTCGCGCTTCAACGGTGAGGTCGGCGCCGCTCGAGACCGTAAAATGAACCCAGCTAACGCGGT
ATCGATGGAGGTGAGGGCCA

Downstream 100 bases:

>100_bases
GCGCGCACCCGCACGGTGGGTAGGCGCGGAAAAGACCAGGTATTAGGAGAGGCAAGCGTGGCACGCGACTATTACGGGCT
GCTCGGCGTGAGCCGAGGCG

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MGSADERRFEVLRAIVADFVATKEPIGSKTLVERHNLGVSSATVRNDMAVLEAEGYITQPHTSSGRVPTEKGYREFVDRL
DDVKPLSAAERRAIQNFLESGVDLDDVLRRAVRLLAQLTRQVAIVQYPTLSSSTVRHLEVIALTPARLLMVVITDSGRVD
QRIVELGDVIDDHELSRLREMLGQALVGKKLSAASVAVADLAEQLRSPDGLGDAVGRSATVLLESLVEHSEERLLMGGTA
NLTRNAADFGGSLRSILEALEEQVVVLRLLAAQQEAGKVTVRIGHETAAEQMVGTSMVTTAYGTSDTVYGGMGVLGPTRM
DYPGTIASVAAVAMYIGEVLGAR

Sequences:

>Translated_343_residues
MGSADERRFEVLRAIVADFVATKEPIGSKTLVERHNLGVSSATVRNDMAVLEAEGYITQPHTSSGRVPTEKGYREFVDRL
DDVKPLSAAERRAIQNFLESGVDLDDVLRRAVRLLAQLTRQVAIVQYPTLSSSTVRHLEVIALTPARLLMVVITDSGRVD
QRIVELGDVIDDHELSRLREMLGQALVGKKLSAASVAVADLAEQLRSPDGLGDAVGRSATVLLESLVEHSEERLLMGGTA
NLTRNAADFGGSLRSILEALEEQVVVLRLLAAQQEAGKVTVRIGHETAAEQMVGTSMVTTAYGTSDTVYGGMGVLGPTRM
DYPGTIASVAAVAMYIGEVLGAR
>Mature_342_residues
GSADERRFEVLRAIVADFVATKEPIGSKTLVERHNLGVSSATVRNDMAVLEAEGYITQPHTSSGRVPTEKGYREFVDRLD
DVKPLSAAERRAIQNFLESGVDLDDVLRRAVRLLAQLTRQVAIVQYPTLSSSTVRHLEVIALTPARLLMVVITDSGRVDQ
RIVELGDVIDDHELSRLREMLGQALVGKKLSAASVAVADLAEQLRSPDGLGDAVGRSATVLLESLVEHSEERLLMGGTAN
LTRNAADFGGSLRSILEALEEQVVVLRLLAAQQEAGKVTVRIGHETAAEQMVGTSMVTTAYGTSDTVYGGMGVLGPTRMD
YPGTIASVAAVAMYIGEVLGAR

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 36833; Mature: 36701

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSADERRFEVLRAIVADFVATKEPIGSKTLVERHNLGVSSATVRNDMAVLEAEGYITQP
CCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHCHHEEECCCCEECC
HTSSGRVPTEKGYREFVDRLDDVKPLSAAERRAIQNFLESGVDLDDVLRRAVRLLAQLTR
CCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QVAIVQYPTLSSSTVRHLEVIALTPARLLMVVITDSGRVDQRIVELGDVIDDHELSRLRE
HHHHHCCCCCCCCHHHHHHHEEECHHHEEEEEEECCCCHHHHHHHHHHHHCHHHHHHHHH
MLGQALVGKKLSAASVAVADLAEQLRSPDGLGDAVGRSATVLLESLVEHSEERLLMGGTA
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCC
NLTRNAADFGGSLRSILEALEEQVVVLRLLAAQQEAGKVTVRIGHETAAEQMVGTSMVTT
HHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHE
AYGTSDTVYGGMGVLGPTRMDYPGTIASVAAVAMYIGEVLGAR
ECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GSADERRFEVLRAIVADFVATKEPIGSKTLVERHNLGVSSATVRNDMAVLEAEGYITQP
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHCHHEEECCCCEECC
HTSSGRVPTEKGYREFVDRLDDVKPLSAAERRAIQNFLESGVDLDDVLRRAVRLLAQLTR
CCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QVAIVQYPTLSSSTVRHLEVIALTPARLLMVVITDSGRVDQRIVELGDVIDDHELSRLRE
HHHHHCCCCCCCCHHHHHHHEEECHHHEEEEEEECCCCHHHHHHHHHHHHCHHHHHHHHH
MLGQALVGKKLSAASVAVADLAEQLRSPDGLGDAVGRSATVLLESLVEHSEERLLMGGTA
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCC
NLTRNAADFGGSLRSILEALEEQVVVLRLLAAQQEAGKVTVRIGHETAAEQMVGTSMVTT
HHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHE
AYGTSDTVYGGMGVLGPTRMDYPGTIASVAAVAMYIGEVLGAR
ECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA