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The map label for this gene is sufS [C]

Identifier: 41408218

GI number: 41408218

Start: 2347936

End: 2349948

Strand: Reverse

Name: sufS [C]

Synonym: MAP2120c

Alternate gene names: 41408218

Gene position: 2349948-2347936 (Counterclockwise)

Preceding gene: 41408219

Following gene: 41408215

Centisome position: 48.66

GC content: 71.73

Gene sequence:

>2013_bases
ATGAGTACAAGTGAGTACCGAGCGGTAGACGCCGAAAGCGACCTGCCCATCAGCGCCGCGGAACTCGCCGCGCTGGCCAG
CCAGCTGTATGCGGCCAGCATCCGCCCGGGCCCCGACAGCCCGCCGCAGCAGGCGCCGGTGGCACCTCGCGGCAGCGTGC
CGGACGCCACGGCGGCAACCTCGGCCGGGCGGACCGCCGCCGGCACGGCCGACGTGTACCCGGGACCGGTTCCGCAGGTC
GGTGGGCGCGACGTCTACCTGCCGCCCCCGGCGTCTCCCGCCCCCGAAGCACCCCCGCAGGCGGCGCCGCCCGCCCCGCG
CGGCAGCGCGCCGGACGCCACGGCGGCCACGTCGGCCGGGCGGGCGGCCGCCGGCACCAGCGACGTGTATTCGTCATGGG
TGCCGCAGCTGGGAGTCGCCGACATCTATCTCGGGGCTCCGACGCCCGCCGGGCCGGAGGCGCCGCCGCAGAGCGCGCCG
CCCGCCCCCCGCGGCCAGGTGCCCGACACGACCGCCGCGGCCACCGCCTACGGCGCCGACCTGAGCGCGTTCGCGGTGCC
CACCGGCATCGTGTCCACCGCGCCCGGTGTGCAGGCCGGGACGGCGCCGCCCGTCCCTGTCGTTCCGCGGGCCGCGACGG
CGCCGTCGTGGCTGCCCGAGGCGCCCTCGGTCGCCGACCTGGGCTGGTCCGACGCACCCGCACCCGATGCGCCGGCCGGC
GACGAGCATGACTACCACTTCCTGACCAAAACCGATCCGGTGCCGCAGTTTCGCGACGAGCACGAGGTTTTCGACGTCGC
CGCGATTCGCTCGGACTTCCCGATCCTGAAGGAGACGGTCAACGGAAAACCGTTGATCTGGTTCGACAATGCGGCGACGA
CGCAGAAGCCGCAGGTGGTCATCGACCGGCTGTCGCACTTCTACGCCCACGAGAACTCGAACATTCACCGCGCCGCACAC
GAATTGGCGGCCCGCGCCACCGACGCCTACGAGGAGGCCCGCGACACCGTCGCCGAGTTCATCGGCGCGCCCAGCTCGGA
CAACATCGTGTTCGTGCGGGGCACCACCGAGGCGATCAACCTGGTGGCCCACGCGTGGGGCGCCAAGCATCTGCAGCCCG
GCGACGAGATCGTCATCACCCACCTGGAGCACCACGCGAACATCGTTCCCTGGCAGCTGATTTCGCAAAAGACCGGTGCC
ATCCTCAAGGTGGCGCCGATCGACGACGCGGGCAACCTGCTGCTGAGCGAATTCGAGGGGCTGCTGGGCCCGCGGACCAA
GCTGGTCGCGGCCAGCCACGTGTCGAACGCCCTGGGCACCGTGATGCCGGTGGACAAGATCGTCGAGTTGGGTCACCGCT
ACGGCGCCCGGGTGCTGATCGACGGCGCCCAGTCCATCCAGCACATCCCGATCGACGTCGCCGAACTCGGCGCCGACTTC
TTCGTCTTCTCCGGCCATAAGATCTACGGCCCCACCGGGATTGGTGCGCTCTACGGCACCGAGGAAGCGCTCACCGAGAC
CCCGCCGTGGCAGGGCGGCGGCCACATGATCGCCGACGTCACCCTGGAACGCTCGCTGTACCAGGGGCCGCCGACGAAGT
TCGAGGCCGGCACCGGCAACATCGCCGACGCCGTCGGGCTGACCGAGGCGCTGCGCTACGTGCAACGGTTGGGCGTCGAG
CGGATCGCCGCCTACGAGCACGCCCTGCTGGAGTACGCGACACCGCGGTTGGCCGACATCCCCGGGGTCCGCCTGATCGG
GACCGCGCAGGAGAAGGCCAGCGTGTTGTCCTTCGTGCTGGCGGGCCACGAACCGCTCGAGGTGGGCAAGGCGCTCAACG
CCGAGGGCATCGCGGTGCGGGCGGGCCACCACTGCGCCCAGCCGGCCCTGCGCCGACTGGGACTCGAGGCCACCGTGCGC
CCGTCGTTCGCCTTCTACAACACGTTCGAGGAGATCGACGTGTTCCTGCGCGCGGTGCGCCGGATAGCCGAGGGCGGCGC
CAACGTCGGCTGA

Upstream 100 bases:

>100_bases
TCGGCGATCGCGACCTACCTGGTCACGCTGTACACCTCCCTGGCCGTCCTGACCGATGACGCGCTCGCCGTGCTCGACGA
CGTCGCGGTGGATCAGTTCC

Downstream 100 bases:

>100_bases
ACCGCCGGCCGGGCGGTTAAATCCTAAGTGGTTACGCCCCAACCGAATACGCGCGAGGTCAGCAGCACGATGCCCAGCGA
GACGGTGGCGACCACGGTCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 670; Mature: 669

Protein sequence:

>670_residues
MSTSEYRAVDAESDLPISAAELAALASQLYAASIRPGPDSPPQQAPVAPRGSVPDATAATSAGRTAAGTADVYPGPVPQV
GGRDVYLPPPASPAPEAPPQAAPPAPRGSAPDATAATSAGRAAAGTSDVYSSWVPQLGVADIYLGAPTPAGPEAPPQSAP
PAPRGQVPDTTAAATAYGADLSAFAVPTGIVSTAPGVQAGTAPPVPVVPRAATAPSWLPEAPSVADLGWSDAPAPDAPAG
DEHDYHFLTKTDPVPQFRDEHEVFDVAAIRSDFPILKETVNGKPLIWFDNAATTQKPQVVIDRLSHFYAHENSNIHRAAH
ELAARATDAYEEARDTVAEFIGAPSSDNIVFVRGTTEAINLVAHAWGAKHLQPGDEIVITHLEHHANIVPWQLISQKTGA
ILKVAPIDDAGNLLLSEFEGLLGPRTKLVAASHVSNALGTVMPVDKIVELGHRYGARVLIDGAQSIQHIPIDVAELGADF
FVFSGHKIYGPTGIGALYGTEEALTETPPWQGGGHMIADVTLERSLYQGPPTKFEAGTGNIADAVGLTEALRYVQRLGVE
RIAAYEHALLEYATPRLADIPGVRLIGTAQEKASVLSFVLAGHEPLEVGKALNAEGIAVRAGHHCAQPALRRLGLEATVR
PSFAFYNTFEEIDVFLRAVRRIAEGGANVG

Sequences:

>Translated_670_residues
MSTSEYRAVDAESDLPISAAELAALASQLYAASIRPGPDSPPQQAPVAPRGSVPDATAATSAGRTAAGTADVYPGPVPQV
GGRDVYLPPPASPAPEAPPQAAPPAPRGSAPDATAATSAGRAAAGTSDVYSSWVPQLGVADIYLGAPTPAGPEAPPQSAP
PAPRGQVPDTTAAATAYGADLSAFAVPTGIVSTAPGVQAGTAPPVPVVPRAATAPSWLPEAPSVADLGWSDAPAPDAPAG
DEHDYHFLTKTDPVPQFRDEHEVFDVAAIRSDFPILKETVNGKPLIWFDNAATTQKPQVVIDRLSHFYAHENSNIHRAAH
ELAARATDAYEEARDTVAEFIGAPSSDNIVFVRGTTEAINLVAHAWGAKHLQPGDEIVITHLEHHANIVPWQLISQKTGA
ILKVAPIDDAGNLLLSEFEGLLGPRTKLVAASHVSNALGTVMPVDKIVELGHRYGARVLIDGAQSIQHIPIDVAELGADF
FVFSGHKIYGPTGIGALYGTEEALTETPPWQGGGHMIADVTLERSLYQGPPTKFEAGTGNIADAVGLTEALRYVQRLGVE
RIAAYEHALLEYATPRLADIPGVRLIGTAQEKASVLSFVLAGHEPLEVGKALNAEGIAVRAGHHCAQPALRRLGLEATVR
PSFAFYNTFEEIDVFLRAVRRIAEGGANVG
>Mature_669_residues
STSEYRAVDAESDLPISAAELAALASQLYAASIRPGPDSPPQQAPVAPRGSVPDATAATSAGRTAAGTADVYPGPVPQVG
GRDVYLPPPASPAPEAPPQAAPPAPRGSAPDATAATSAGRAAAGTSDVYSSWVPQLGVADIYLGAPTPAGPEAPPQSAPP
APRGQVPDTTAAATAYGADLSAFAVPTGIVSTAPGVQAGTAPPVPVVPRAATAPSWLPEAPSVADLGWSDAPAPDAPAGD
EHDYHFLTKTDPVPQFRDEHEVFDVAAIRSDFPILKETVNGKPLIWFDNAATTQKPQVVIDRLSHFYAHENSNIHRAAHE
LAARATDAYEEARDTVAEFIGAPSSDNIVFVRGTTEAINLVAHAWGAKHLQPGDEIVITHLEHHANIVPWQLISQKTGAI
LKVAPIDDAGNLLLSEFEGLLGPRTKLVAASHVSNALGTVMPVDKIVELGHRYGARVLIDGAQSIQHIPIDVAELGADFF
VFSGHKIYGPTGIGALYGTEEALTETPPWQGGGHMIADVTLERSLYQGPPTKFEAGTGNIADAVGLTEALRYVQRLGVER
IAAYEHALLEYATPRLADIPGVRLIGTAQEKASVLSFVLAGHEPLEVGKALNAEGIAVRAGHHCAQPALRRLGLEATVRP
SFAFYNTFEEIDVFLRAVRRIAEGGANVG

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily

Homologues:

Organism=Homo sapiens, GI32307132, Length=398, Percent_Identity=24.6231155778894, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI156713448, Length=284, Percent_Identity=28.169014084507, Blast_Score=76, Evalue=1e-13,
Organism=Escherichia coli, GI1787970, Length=401, Percent_Identity=47.3815461346633, Blast_Score=388, Evalue=1e-109,
Organism=Escherichia coli, GI1789175, Length=407, Percent_Identity=40.2948402948403, Blast_Score=299, Evalue=3e-82,
Organism=Escherichia coli, GI48994898, Length=394, Percent_Identity=28.6802030456853, Blast_Score=119, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI25143064, Length=406, Percent_Identity=25.8620689655172, Blast_Score=105, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI193211090, Length=417, Percent_Identity=24.9400479616307, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6319831, Length=229, Percent_Identity=31.4410480349345, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI20129463, Length=420, Percent_Identity=27.1428571428571, Blast_Score=110, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CSD_MYCPA (Q9KII6)

Other databases:

- EMBL:   AF232751
- EMBL:   AE016958
- RefSeq:   NP_961054.1
- ProteinModelPortal:   Q9KII6
- SMR:   Q9KII6
- EnsemblBacteria:   EBMYCT00000039479
- GeneID:   2719273
- GenomeReviews:   AE016958_GR
- KEGG:   mpa:MAP2120c
- NMPDR:   fig|262316.1.peg.2120
- GeneTree:   EBGT00050000015336
- HOGENOM:   HBG635316
- OMA:   EIVITHL
- ProtClustDB:   CLSK763550
- BRENDA:   2.8.1.7
- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- TIGRFAMs:   TIGR01979

Pfam domain/function: PF00266 Aminotran_5; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.8.1.7

Molecular weight: Translated: 69914; Mature: 69783

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: ACT_SITE 640-640

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSEYRAVDAESDLPISAAELAALASQLYAASIRPGPDSPPQQAPVAPRGSVPDATAAT
CCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHC
SAGRTAAGTADVYPGPVPQVGGRDVYLPPPASPAPEAPPQAAPPAPRGSAPDATAATSAG
CCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCC
RAAAGTSDVYSSWVPQLGVADIYLGAPTPAGPEAPPQSAPPAPRGQVPDTTAAATAYGAD
CCCCCCHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCC
LSAFAVPTGIVSTAPGVQAGTAPPVPVVPRAATAPSWLPEAPSVADLGWSDAPAPDAPAG
CHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DEHDYHFLTKTDPVPQFRDEHEVFDVAAIRSDFPILKETVNGKPLIWFDNAATTQKPQVV
CCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCHHHHHHCCCCEEEEECCCCCCCCHHHH
IDRLSHFYAHENSNIHRAAHELAARATDAYEEARDTVAEFIGAPSSDNIVFVRGTTEAIN
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHH
LVAHAWGAKHLQPGDEIVITHLEHHANIVPWQLISQKTGAILKVAPIDDAGNLLLSEFEG
HHHHHHCCCCCCCCCCEEEEEEHHCCCCCCHHHHHCCCCCEEEEECCCCCHHHHHHHHHH
LLGPRTKLVAASHVSNALGTVMPVDKIVELGHRYGARVLIDGAQSIQHIPIDVAELGADF
HCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECCHHHEECCCCHHHCCCCE
FVFSGHKIYGPTGIGALYGTEEALTETPPWQGGGHMIADVTLERSLYQGPPTKFEAGTGN
EEECCCEEECCCCCCHHHCCHHHHHCCCCCCCCCEEEEEEEHHHHHHCCCCCCCCCCCCC
IADAVGLTEALRYVQRLGVERIAAYEHALLEYATPRLADIPGVRLIGTAQEKASVLSFVL
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHH
AGHEPLEVGKALNAEGIAVRAGHHCAQPALRRLGLEATVRPSFAFYNTFEEIDVFLRAVR
HCCCHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHH
RIAEGGANVG
HHHHCCCCCC
>Mature Secondary Structure 
STSEYRAVDAESDLPISAAELAALASQLYAASIRPGPDSPPQQAPVAPRGSVPDATAAT
CCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHC
SAGRTAAGTADVYPGPVPQVGGRDVYLPPPASPAPEAPPQAAPPAPRGSAPDATAATSAG
CCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCC
RAAAGTSDVYSSWVPQLGVADIYLGAPTPAGPEAPPQSAPPAPRGQVPDTTAAATAYGAD
CCCCCCHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCC
LSAFAVPTGIVSTAPGVQAGTAPPVPVVPRAATAPSWLPEAPSVADLGWSDAPAPDAPAG
CHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DEHDYHFLTKTDPVPQFRDEHEVFDVAAIRSDFPILKETVNGKPLIWFDNAATTQKPQVV
CCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCHHHHHHCCCCEEEEECCCCCCCCHHHH
IDRLSHFYAHENSNIHRAAHELAARATDAYEEARDTVAEFIGAPSSDNIVFVRGTTEAIN
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHH
LVAHAWGAKHLQPGDEIVITHLEHHANIVPWQLISQKTGAILKVAPIDDAGNLLLSEFEG
HHHHHHCCCCCCCCCCEEEEEEHHCCCCCCHHHHHCCCCCEEEEECCCCCHHHHHHHHHH
LLGPRTKLVAASHVSNALGTVMPVDKIVELGHRYGARVLIDGAQSIQHIPIDVAELGADF
HCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECCHHHEECCCCHHHCCCCE
FVFSGHKIYGPTGIGALYGTEEALTETPPWQGGGHMIADVTLERSLYQGPPTKFEAGTGN
EEECCCEEECCCCCCHHHCCHHHHHCCCCCCCCCEEEEEEEHHHHHHCCCCCCCCCCCCC
IADAVGLTEALRYVQRLGVERIAAYEHALLEYATPRLADIPGVRLIGTAQEKASVLSFVL
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHH
AGHEPLEVGKALNAEGIAVRAGHHCAQPALRRLGLEATVRPSFAFYNTFEEIDVFLRAVR
HCCCHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHH
RIAEGGANVG
HHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA