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The map label for this gene is rocE

Identifier: 41408191

GI number: 41408191

Start: 2314162

End: 2315613

Strand: Reverse

Name: rocE

Synonym: MAP2093c

Alternate gene names: 41408191

Gene position: 2315613-2314162 (Counterclockwise)

Preceding gene: 41408192

Following gene: 41408187

Centisome position: 47.94

GC content: 67.63

Gene sequence:

>1452_bases
TTGCCAGCCACGCCGATCGGCTTGAGAGCACAGCTGCTGCGACGGCGCCCGGTGGTGGGCGCACACGTGGCCCCCGGCAC
CGCCGATCACCTCCGGCGCGGCATCGGGACCTTCCAGCTGACCATGTTCGGGGTCGGGTCGACGATCGGCACCGGCATCT
TCTTCGTCATGTCCCAGGCCGTCCCCGAGGCCGGCCCCGCGGTCATCGTCTCCTTCCTGCTCGCCGGCGTCGCCGCCGGG
CTGGCGGCCGTGTGCTACGCCGAATTGGCTTCGGCGGTACCGGTTTCGGGCTCGTCGTATTCCTACGCCTACACCACGCT
GGGCGAGGTGGTCGCGATGGGCGTGGCGGCCTGCCTGCTGCTGGAATACGGGGTGGCCACCGCCGCGGTCTCGGTGAACT
GGAGCGGCTACCTGAACAAGCTGCTGAGCAATGTCGTGGGATTCCAACTGCCGCATGCCTTGTCGGCCGCACCGTGGGAC
GCGCAACCCGGCTACGTCAATCTGCCGGCGGTCATGCTGATCGGGATGTGCGCCCTGTTGCTGATCCGCGGGGCCAGCGA
ATCGGCCAAGGTCAACGCGATCATGGTGATGATCAAGCTCGGCGTGCTCGTCGTATTCGGGATCCTTGCCTTCACCGCGT
TCGACGTGCACCACCTCGACGACTTCGCGCCGTTCGGTGTCGCCGGTGTGGGCACGGCCGCCGGCACCATCTTCTTCTCC
TACATCGGCCTCGATGCGGTGTCCACCGCGGGCGACGAGGTGACGAACCCGCAGAAGACCATGCCGCGCGCGCTGATCGC
CGCGCTGTCGACCGTCACCGGCGTGTACGTGTTCGTCGCGCTCGCCGCGCTGGGGACGCAGCCGTGGCAGGACTTTGGCG
GTCAGCAGGAGGCCGGGCTCGCCACCATCCTCGACCATGTCACGCACGGCAGCTGGGCCAGCACCATTTTGGCTGCGGGC
GCGGTCATTTCGATCTTCAGCGTCACGCTGGTCACCATGTACGGCATCACCCGCATCCTGTTCGCCATGGGCCGGGACGG
GCTGCTGCCGCCGCGGTTCGCCAGGGTGAACCCGCGCACCATGACGCCGGTGAACAACACCGTGATCGTCGCGGTCGCCG
CCTCTACCCTGGCCGCGTTCATTCCGCTGCAAAACCTGGCCGACATGGTCTCGATCGGCACGCTCACCGCGTTCGTCGTC
GTCTCCGTCGGGGTGATCGTGTTACGGGTGCGCGAGCCCGACCTGCCACGCGGGTTCCGGGTCCCGGGTTACCCTGTCAC
GCCCGTCCTTTCGATCATGGCCTGCGGGTACATCCTGGCGAGCTTGCACTGGTACACCTGGATCGCGTTCAGCGGCTGGG
TGTTGCTGGCGCTGATCTTCTACTTCGTCTGGGGCCGTCACCACAGCGCACTCAACGACGCGGCGGTCGACCCGTCCGGC
CAGGAGCGCTGA

Upstream 100 bases:

>100_bases
GTGGTCACCGCGCAGGAGATCGACTGGGCGGTCGGCCAGCTTGCTGCGGTGTTGCGGGAGGCTGCTTCATAATCAGCTGA
CCCGGCAACAGGAGGGGCAA

Downstream 100 bases:

>100_bases
CCGGCTTACCGGCGGGCGGCGGCGTTGGCCGCCGCCTGAGCCCGCCTCAGTGTCGTGGCGACATCGCCGCGGCCGGAGAA
CATTTCGTCGAAGTAGGGCC

Product: RocE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 482

Protein sequence:

>483_residues
MPATPIGLRAQLLRRRPVVGAHVAPGTADHLRRGIGTFQLTMFGVGSTIGTGIFFVMSQAVPEAGPAVIVSFLLAGVAAG
LAAVCYAELASAVPVSGSSYSYAYTTLGEVVAMGVAACLLLEYGVATAAVSVNWSGYLNKLLSNVVGFQLPHALSAAPWD
AQPGYVNLPAVMLIGMCALLLIRGASESAKVNAIMVMIKLGVLVVFGILAFTAFDVHHLDDFAPFGVAGVGTAAGTIFFS
YIGLDAVSTAGDEVTNPQKTMPRALIAALSTVTGVYVFVALAALGTQPWQDFGGQQEAGLATILDHVTHGSWASTILAAG
AVISIFSVTLVTMYGITRILFAMGRDGLLPPRFARVNPRTMTPVNNTVIVAVAASTLAAFIPLQNLADMVSIGTLTAFVV
VSVGVIVLRVREPDLPRGFRVPGYPVTPVLSIMACGYILASLHWYTWIAFSGWVLLALIFYFVWGRHHSALNDAAVDPSG
QER

Sequences:

>Translated_483_residues
MPATPIGLRAQLLRRRPVVGAHVAPGTADHLRRGIGTFQLTMFGVGSTIGTGIFFVMSQAVPEAGPAVIVSFLLAGVAAG
LAAVCYAELASAVPVSGSSYSYAYTTLGEVVAMGVAACLLLEYGVATAAVSVNWSGYLNKLLSNVVGFQLPHALSAAPWD
AQPGYVNLPAVMLIGMCALLLIRGASESAKVNAIMVMIKLGVLVVFGILAFTAFDVHHLDDFAPFGVAGVGTAAGTIFFS
YIGLDAVSTAGDEVTNPQKTMPRALIAALSTVTGVYVFVALAALGTQPWQDFGGQQEAGLATILDHVTHGSWASTILAAG
AVISIFSVTLVTMYGITRILFAMGRDGLLPPRFARVNPRTMTPVNNTVIVAVAASTLAAFIPLQNLADMVSIGTLTAFVV
VSVGVIVLRVREPDLPRGFRVPGYPVTPVLSIMACGYILASLHWYTWIAFSGWVLLALIFYFVWGRHHSALNDAAVDPSG
QER
>Mature_482_residues
PATPIGLRAQLLRRRPVVGAHVAPGTADHLRRGIGTFQLTMFGVGSTIGTGIFFVMSQAVPEAGPAVIVSFLLAGVAAGL
AAVCYAELASAVPVSGSSYSYAYTTLGEVVAMGVAACLLLEYGVATAAVSVNWSGYLNKLLSNVVGFQLPHALSAAPWDA
QPGYVNLPAVMLIGMCALLLIRGASESAKVNAIMVMIKLGVLVVFGILAFTAFDVHHLDDFAPFGVAGVGTAAGTIFFSY
IGLDAVSTAGDEVTNPQKTMPRALIAALSTVTGVYVFVALAALGTQPWQDFGGQQEAGLATILDHVTHGSWASTILAAGA
VISIFSVTLVTMYGITRILFAMGRDGLLPPRFARVNPRTMTPVNNTVIVAVAASTLAAFIPLQNLADMVSIGTLTAFVVV
SVGVIVLRVREPDLPRGFRVPGYPVTPVLSIMACGYILASLHWYTWIAFSGWVLLALIFYFVWGRHHSALNDAAVDPSGQ
ER

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI114326544, Length=441, Percent_Identity=31.9727891156463, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI114326550, Length=441, Percent_Identity=31.9727891156463, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI4507047, Length=441, Percent_Identity=32.8798185941043, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI258645169, Length=431, Percent_Identity=32.2505800464037, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI258614005, Length=431, Percent_Identity=30.8584686774942, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI258614003, Length=431, Percent_Identity=30.8584686774942, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI110347453, Length=390, Percent_Identity=33.5897435897436, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI181337167, Length=423, Percent_Identity=31.2056737588652, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI33286428, Length=408, Percent_Identity=24.7549019607843, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI71979932, Length=431, Percent_Identity=25.5220417633411, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI187423910, Length=475, Percent_Identity=21.6842105263158, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI7657591, Length=475, Percent_Identity=21.6842105263158, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI186910308, Length=417, Percent_Identity=23.021582733813, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI186910306, Length=417, Percent_Identity=23.021582733813, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI186910304, Length=417, Percent_Identity=23.021582733813, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI115648063, Length=442, Percent_Identity=21.4932126696833, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI115648022, Length=442, Percent_Identity=21.4932126696833, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI7657683, Length=380, Percent_Identity=21.0526315789474, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI87081869, Length=435, Percent_Identity=22.9885057471264, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786302, Length=375, Percent_Identity=24.5333333333333, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788480, Length=450, Percent_Identity=23.7777777777778, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786694, Length=389, Percent_Identity=24.1645244215938, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789017, Length=406, Percent_Identity=24.384236453202, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI87082250, Length=473, Percent_Identity=24.3128964059197, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786602, Length=469, Percent_Identity=22.1748400852878, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87081708, Length=441, Percent_Identity=22.2222222222222, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI2367353, Length=359, Percent_Identity=25.0696378830084, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082023, Length=378, Percent_Identity=22.2222222222222, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87081915, Length=447, Percent_Identity=23.0425055928412, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=417, Percent_Identity=32.6139088729017, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17533459, Length=414, Percent_Identity=30.9178743961353, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17531343, Length=401, Percent_Identity=31.1720698254364, Blast_Score=171, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI32566699, Length=324, Percent_Identity=24.0740740740741, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24668806, Length=430, Percent_Identity=32.5581395348837, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI21356285, Length=430, Percent_Identity=32.5581395348837, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24668802, Length=430, Percent_Identity=32.5581395348837, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24667468, Length=407, Percent_Identity=32.1867321867322, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24666159, Length=430, Percent_Identity=32.093023255814, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI221512776, Length=430, Percent_Identity=32.093023255814, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI281366235, Length=425, Percent_Identity=29.6470588235294, Blast_Score=155, Evalue=7e-38,
Organism=Drosophila melanogaster, GI116007820, Length=425, Percent_Identity=29.6470588235294, Blast_Score=155, Evalue=7e-38,
Organism=Drosophila melanogaster, GI161077963, Length=430, Percent_Identity=29.7674418604651, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI116007818, Length=427, Percent_Identity=29.5081967213115, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI85725152, Length=427, Percent_Identity=29.5081967213115, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI221331183, Length=426, Percent_Identity=23.7089201877934, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17647653, Length=426, Percent_Identity=23.7089201877934, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24664379, Length=426, Percent_Identity=23.7089201877934, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI45550968, Length=435, Percent_Identity=22.9885057471264, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI19921172, Length=435, Percent_Identity=22.9885057471264, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24641993, Length=420, Percent_Identity=23.0952380952381, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641995, Length=420, Percent_Identity=23.0952380952381, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21357367, Length=451, Percent_Identity=21.7294900221729, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50581; Mature: 50450

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPATPIGLRAQLLRRRPVVGAHVAPGTADHLRRGIGTFQLTMFGVGSTIGTGIFFVMSQA
CCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHH
VPEAGPAVIVSFLLAGVAAGLAAVCYAELASAVPVSGSSYSYAYTTLGEVVAMGVAACLL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LEYGVATAAVSVNWSGYLNKLLSNVVGFQLPHALSAAPWDAQPGYVNLPAVMLIGMCALL
HHHHHHHEEEEECHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
LIRGASESAKVNAIMVMIKLGVLVVFGILAFTAFDVHHLDDFAPFGVAGVGTAAGTIFFS
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
YIGLDAVSTAGDEVTNPQKTMPRALIAALSTVTGVYVFVALAALGTQPWQDFGGQQEAGL
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHH
ATILDHVTHGSWASTILAAGAVISIFSVTLVTMYGITRILFAMGRDGLLPPRFARVNPRT
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
MTPVNNTVIVAVAASTLAAFIPLQNLADMVSIGTLTAFVVVSVGVIVLRVREPDLPRGFR
ECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCC
VPGYPVTPVLSIMACGYILASLHWYTWIAFSGWVLLALIFYFVWGRHHSALNDAAVDPSG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
QER
CCC
>Mature Secondary Structure 
PATPIGLRAQLLRRRPVVGAHVAPGTADHLRRGIGTFQLTMFGVGSTIGTGIFFVMSQA
CCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHH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CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]