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The map label for this gene is ubiE [H]

Identifier: 41408173

GI number: 41408173

Start: 2283668

End: 2284306

Strand: Reverse

Name: ubiE [H]

Synonym: MAP2075c

Alternate gene names: 41408173

Gene position: 2284306-2283668 (Counterclockwise)

Preceding gene: 41408174

Following gene: 41408172

Centisome position: 47.3

GC content: 66.82

Gene sequence:

>639_bases
ATGACCGCACCGCAGCGGCGAGGGCTGAACGACGTCGTCACGCGGATGTGGAGCTTCCTGGCGCCGGCGTATGACCTGCC
CTTCCTGCAGCAGTGGGTGTACCGGCCTCCGCACAACGAGGTGATAGCCCAGCTACGCAACCACGGTTCGCGCAGAATCG
CCGACATCGCTTGCGGCACAGGGATACTCAGCGAGCGGATCCAGCGCGAACTGAATCCCGACGAGATCTACGGCGTGGAC
ATGTCCGACGGCATGCTCAACCAGGCGCGGGCGAAATCGGACCGGGTGCAGTGGTTGCGTGCGCCGGCCGAACAGCTCCC
GTTTGACGACGGTGCGCTCGACGCCATCGTGACGACGTCGGCGTTCCACTTCTTCGACCAGCCGGCGGCGTTGCGGGAAT
TCCATCGCGTGCTGGCCCCCGGGGGGTTGGTGGCCGTCTCGGCGCTCAGTACCCGGCGACCGCTGCTGCAGGCATCCGCC
GACAGCAGGTGGAAGCCGCAGCACAACGCGTCGGCTCCCGAGATGCGCAAGCTGTTCGAGGACGCGGGGTTCGTGATCGG
CGATCAGTATCGGATCCCGCGGCCGGCCTGGACGCGCCTGGTTTCTGACCTGCTGACCGTCGGCACCAAACCCGACTAG

Upstream 100 bases:

>100_bases
TGAGTCAGCTGTTGGCCGACGCCGGACTCGAGGCGATCCCGCAGACCAACGACTCCGTGTCGGTGGCCGATACCATCTAC
TACAGCTCGGTGCTGGCAAA

Downstream 100 bases:

>100_bases
TGATGCCGGGACGAAATGCGTTCGCCGGCAACGGCATAACTGACGACGCCCGCCTCACCTGATCGGCGAGGCGGGCGTCG
TTTCAGCTATGGCTCACAGC

Product: hypothetical protein

Products: S-adenosyl-L-homocysteine +rRNA containing Nmethylguanine [C]

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MTAPQRRGLNDVVTRMWSFLAPAYDLPFLQQWVYRPPHNEVIAQLRNHGSRRIADIACGTGILSERIQRELNPDEIYGVD
MSDGMLNQARAKSDRVQWLRAPAEQLPFDDGALDAIVTTSAFHFFDQPAALREFHRVLAPGGLVAVSALSTRRPLLQASA
DSRWKPQHNASAPEMRKLFEDAGFVIGDQYRIPRPAWTRLVSDLLTVGTKPD

Sequences:

>Translated_212_residues
MTAPQRRGLNDVVTRMWSFLAPAYDLPFLQQWVYRPPHNEVIAQLRNHGSRRIADIACGTGILSERIQRELNPDEIYGVD
MSDGMLNQARAKSDRVQWLRAPAEQLPFDDGALDAIVTTSAFHFFDQPAALREFHRVLAPGGLVAVSALSTRRPLLQASA
DSRWKPQHNASAPEMRKLFEDAGFVIGDQYRIPRPAWTRLVSDLLTVGTKPD
>Mature_211_residues
TAPQRRGLNDVVTRMWSFLAPAYDLPFLQQWVYRPPHNEVIAQLRNHGSRRIADIACGTGILSERIQRELNPDEIYGVDM
SDGMLNQARAKSDRVQWLRAPAEQLPFDDGALDAIVTTSAFHFFDQPAALREFHRVLAPGGLVAVSALSTRRPLLQASAD
SRWKPQHNASAPEMRKLFEDAGFVIGDQYRIPRPAWTRLVSDLLTVGTKPD

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.51 [C]

Molecular weight: Translated: 23843; Mature: 23712

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPQRRGLNDVVTRMWSFLAPAYDLPFLQQWVYRPPHNEVIAQLRNHGSRRIADIACGT
CCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHH
GILSERIQRELNPDEIYGVDMSDGMLNQARAKSDRVQWLRAPAEQLPFDDGALDAIVTTS
HHHHHHHHHHCCHHHEEECCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHH
AFHFFDQPAALREFHRVLAPGGLVAVSALSTRRPLLQASADSRWKPQHNASAPEMRKLFE
HHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
DAGFVIGDQYRIPRPAWTRLVSDLLTVGTKPD
HCCCEECCCCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TAPQRRGLNDVVTRMWSFLAPAYDLPFLQQWVYRPPHNEVIAQLRNHGSRRIADIACGT
CCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHH
GILSERIQRELNPDEIYGVDMSDGMLNQARAKSDRVQWLRAPAEQLPFDDGALDAIVTTS
HHHHHHHHHHCCHHHEEECCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHH
AFHFFDQPAALREFHRVLAPGGLVAVSALSTRRPLLQASADSRWKPQHNASAPEMRKLFE
HHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
DAGFVIGDQYRIPRPAWTRLVSDLLTVGTKPD
HCCCEECCCCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Unidentified protein factor B [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-methionine; rRNA [C]

Specific reaction: S-Adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine +rRNA containing Nmethylguanine [C]

General reaction: Methyl group transfer [C]

Inhibitor: Mg2+; Unidentified protein factor A1 [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]