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The map label for this gene is 41408116

Identifier: 41408116

GI number: 41408116

Start: 2226157

End: 2227644

Strand: Reverse

Name: 41408116

Synonym: MAP2018c

Alternate gene names: NA

Gene position: 2227644-2226157 (Counterclockwise)

Preceding gene: 41408117

Following gene: 41408111

Centisome position: 46.12

GC content: 66.4

Gene sequence:

>1488_bases
GTGGTCACAGACCGTTTCGACGCGATCATCGTGGGTGCGGGTTTCGGCGGCATCGGCGCCGCCATCCAGCTCAAGCGCCT
GGGCTTTGACAACATCGTCATCCTCGACCGCGAGGACGACCTGGGCGGAACCTGGCACGTCAACCACTACCCGGGCATCG
CCGTCGACATCCCGTCCACCACCTACTCGTACTGGTTCGAGCCGAACCCCGGCTGGTCACGGCTGTTCGCGCCGGGCGGC
GAGGTGAAGCAGTACGCCGCCGACGTCGCCGACAAATACGACGTGCGCCGGCACATGCGGTTCAACACCACCGTCGAGGG
CGCGCAGTGGGACGAGGACGCCGAGGTGTGGCGGGTCGCGCTGGCCGGCGGCGAGAGCCTGACCACCCGCTTCCTGATCA
CCGCGACCGGCTTCCTGTCGCAGCCGCACACTCCCGACATCCCGGGCATCGGCAGCTTCGGGGGAAAGGTCGTGCACACC
ACGGCGTGGGACCACGACTACCGCTACCAGGGCCGGCGCATCGCGGTCATCGGCACCGGGGCGTCCGCCGTGCAGGTCGT
CCCGGAGTTGGCCAAGGAGGCCGGGGAGCTGACCGTCTACCAGCGCACCGCCACCCACGTGCTGCCCAAGGTGGACTTCG
AGTTCGACCCGGCGGTGCGGCGCCTGTTCGCGCGGGTGCCGGCGGCGCAGCGCGCGCTGCGCTGGGTGACCGACGTGCTG
CTCGAGATCATCATGATCGTCGGCGCGTTGCACTTCAAGGAATCCCGCGGCCGTGGCAACATCTCCGCCTCAGATCTGGC
CAAGATCAACCGATTTCGGTGGATCCGGGACAAGGAACTGCGCGCCAAGCTGACGCCGGACTACGATTGCGGCTGCAAGC
GGCCCACCTTCTCCAACAGCTTCTACCGCGTCCTCACCCAGCCGAACGTGCACCTGGAGACCAACCCGATCGAACGGATC
GAGCCGGATGGCATCGTCACCGCTGACGGCCGCAAGACCGTCATCGACACCCTGGTGTTGGCAACGGGTTTCGACCTGTG
GGAGGCCAACTTCCCGGCCATCGAGGTGATCGGCCGCAAGGGCCGCAATCTGGGCAAGTGGTGGCGCGAGACCCGGTTCC
AGGCCTACCAGGGCGTGTCCATGCCGTACTTTCCCAATTACCTGAGCCTGGCCAGCCCGTTCGCCTTCTCCGGCTTGTCC
TTCTTCCACACCATCGAATACCAGATGCGGCACATGGACCGGCTGCTCGGCGAGGTCAAGCGCCGCGGCGCGACCATCTT
CGAGGTCACCGAGGAGGCCAACGACCGGTTCATGGAGCGGATGACCAAACTGCTGGACAATTCGGTGTTCTACGCCGGTA
ACTGCGCCACGTCGCGGTCGTACTACTTCAGTCCCAGCGGCGAGGCCTCGCTGCTGCGGCCCACATCGACGCTGAACTCG
ATCCGCGAAGCCAGCAGCTTCCCGCTCAGCGACTACGTCATCGCCTAG

Upstream 100 bases:

>100_bases
AGCTCGGATGCGCCTGTCGGCGCGGCCTATTAGAGTTGCGTATCTTAGGGAAAGCTTAGGTATTCGTTAAGTATGGGTTA
GGTAGCTACGGAGCAAGGCT

Downstream 100 bases:

>100_bases
CCCGCTCGGCGGTGCGCCGACCCGGTCAGCGGCTGCCCGTCGGACGACTGCAGCAGGCAGATCACCGTGCTCGGGGTGGG
GTTGGCGCCGGTGCGATCCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 495

Protein sequence:

>495_residues
MVTDRFDAIIVGAGFGGIGAAIQLKRLGFDNIVILDREDDLGGTWHVNHYPGIAVDIPSTTYSYWFEPNPGWSRLFAPGG
EVKQYAADVADKYDVRRHMRFNTTVEGAQWDEDAEVWRVALAGGESLTTRFLITATGFLSQPHTPDIPGIGSFGGKVVHT
TAWDHDYRYQGRRIAVIGTGASAVQVVPELAKEAGELTVYQRTATHVLPKVDFEFDPAVRRLFARVPAAQRALRWVTDVL
LEIIMIVGALHFKESRGRGNISASDLAKINRFRWIRDKELRAKLTPDYDCGCKRPTFSNSFYRVLTQPNVHLETNPIERI
EPDGIVTADGRKTVIDTLVLATGFDLWEANFPAIEVIGRKGRNLGKWWRETRFQAYQGVSMPYFPNYLSLASPFAFSGLS
FFHTIEYQMRHMDRLLGEVKRRGATIFEVTEEANDRFMERMTKLLDNSVFYAGNCATSRSYYFSPSGEASLLRPTSTLNS
IREASSFPLSDYVIA

Sequences:

>Translated_495_residues
MVTDRFDAIIVGAGFGGIGAAIQLKRLGFDNIVILDREDDLGGTWHVNHYPGIAVDIPSTTYSYWFEPNPGWSRLFAPGG
EVKQYAADVADKYDVRRHMRFNTTVEGAQWDEDAEVWRVALAGGESLTTRFLITATGFLSQPHTPDIPGIGSFGGKVVHT
TAWDHDYRYQGRRIAVIGTGASAVQVVPELAKEAGELTVYQRTATHVLPKVDFEFDPAVRRLFARVPAAQRALRWVTDVL
LEIIMIVGALHFKESRGRGNISASDLAKINRFRWIRDKELRAKLTPDYDCGCKRPTFSNSFYRVLTQPNVHLETNPIERI
EPDGIVTADGRKTVIDTLVLATGFDLWEANFPAIEVIGRKGRNLGKWWRETRFQAYQGVSMPYFPNYLSLASPFAFSGLS
FFHTIEYQMRHMDRLLGEVKRRGATIFEVTEEANDRFMERMTKLLDNSVFYAGNCATSRSYYFSPSGEASLLRPTSTLNS
IREASSFPLSDYVIA
>Mature_495_residues
MVTDRFDAIIVGAGFGGIGAAIQLKRLGFDNIVILDREDDLGGTWHVNHYPGIAVDIPSTTYSYWFEPNPGWSRLFAPGG
EVKQYAADVADKYDVRRHMRFNTTVEGAQWDEDAEVWRVALAGGESLTTRFLITATGFLSQPHTPDIPGIGSFGGKVVHT
TAWDHDYRYQGRRIAVIGTGASAVQVVPELAKEAGELTVYQRTATHVLPKVDFEFDPAVRRLFARVPAAQRALRWVTDVL
LEIIMIVGALHFKESRGRGNISASDLAKINRFRWIRDKELRAKLTPDYDCGCKRPTFSNSFYRVLTQPNVHLETNPIERI
EPDGIVTADGRKTVIDTLVLATGFDLWEANFPAIEVIGRKGRNLGKWWRETRFQAYQGVSMPYFPNYLSLASPFAFSGLS
FFHTIEYQMRHMDRLLGEVKRRGATIFEVTEEANDRFMERMTKLLDNSVFYAGNCATSRSYYFSPSGEASLLRPTSTLNS
IREASSFPLSDYVIA

Specific function: Unknown

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503755, Length=205, Percent_Identity=26.3414634146341, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4503757, Length=221, Percent_Identity=24.4343891402715, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25145785, Length=359, Percent_Identity=24.2339832869081, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI25150462, Length=373, Percent_Identity=23.5924932975871, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI193202226, Length=217, Percent_Identity=24.8847926267281, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: NA

Molecular weight: Translated: 55679; Mature: 55679

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTDRFDAIIVGAGFGGIGAAIQLKRLGFDNIVILDREDDLGGTWHVNHYPGIAVDIPST
CCCCCCCEEEEECCCCCCCCEEEEEECCCCCEEEEECCCCCCCEEEECCCCCEEEECCCC
TYSYWFEPNPGWSRLFAPGGEVKQYAADVADKYDVRRHMRFNTTVEGAQWDEDAEVWRVA
CEEEEECCCCCHHHEECCCHHHHHHHHHHHHHHHHHHHHEECCEECCCCCCCCHHHEEEE
LAGGESLTTRFLITATGFLSQPHTPDIPGIGSFGGKVVHTTAWDHDYRYQGRRIAVIGTG
ECCCCCHHEEEEEEEEHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCEECCCEEEEEECC
ASAVQVVPELAKEAGELTVYQRTATHVLPKVDFEFDPAVRRLFARVPAAQRALRWVTDVL
CHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHH
LEIIMIVGALHFKESRGRGNISASDLAKINRFRWIRDKELRAKLTPDYDCGCKRPTFSNS
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHEECCCCCCCCCCCCCCCCC
FYRVLTQPNVHLETNPIERIEPDGIVTADGRKTVIDTLVLATGFDLWEANFPAIEVIGRK
CEEEEECCCCEEECCCHHHCCCCCEEECCCCHHHHHHHHHHCCCHHHCCCCCEEEEECCC
GRNLGKWWRETRFQAYQGVSMPYFPNYLSLASPFAFSGLSFFHTIEYQMRHMDRLLGEVK
CCCHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHH
RRGATIFEVTEEANDRFMERMTKLLDNSVFYAGNCATSRSYYFSPSGEASLLRPTSTLNS
HCCCEEEEEHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEECCCCCCEEECCHHHHHH
IREASSFPLSDYVIA
HHHHCCCCCCCEEEC
>Mature Secondary Structure
MVTDRFDAIIVGAGFGGIGAAIQLKRLGFDNIVILDREDDLGGTWHVNHYPGIAVDIPST
CCCCCCCEEEEECCCCCCCCEEEEEECCCCCEEEEECCCCCCCEEEECCCCCEEEECCCC
TYSYWFEPNPGWSRLFAPGGEVKQYAADVADKYDVRRHMRFNTTVEGAQWDEDAEVWRVA
CEEEEECCCCCHHHEECCCHHHHHHHHHHHHHHHHHHHHEECCEECCCCCCCCHHHEEEE
LAGGESLTTRFLITATGFLSQPHTPDIPGIGSFGGKVVHTTAWDHDYRYQGRRIAVIGTG
ECCCCCHHEEEEEEEEHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCEECCCEEEEEECC
ASAVQVVPELAKEAGELTVYQRTATHVLPKVDFEFDPAVRRLFARVPAAQRALRWVTDVL
CHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHH
LEIIMIVGALHFKESRGRGNISASDLAKINRFRWIRDKELRAKLTPDYDCGCKRPTFSNS
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHEECCCCCCCCCCCCCCCCC
FYRVLTQPNVHLETNPIERIEPDGIVTADGRKTVIDTLVLATGFDLWEANFPAIEVIGRK
CEEEEECCCCEEECCCHHHCCCCCEEECCCCHHHHHHHHHHCCCHHHCCCCCEEEEECCC
GRNLGKWWRETRFQAYQGVSMPYFPNYLSLASPFAFSGLSFFHTIEYQMRHMDRLLGEVK
CCCHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHH
RRGATIFEVTEEANDRFMERMTKLLDNSVFYAGNCATSRSYYFSPSGEASLLRPTSTLNS
HCCCEEEEEHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEECCCCCCEEECCHHHHHH
IREASSFPLSDYVIA
HHHHCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]