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The map label for this gene is cobU

Identifier: 41408045

GI number: 41408045

Start: 2148402

End: 2148938

Strand: Direct

Name: cobU

Synonym: MAP1947

Alternate gene names: 41408045

Gene position: 2148402-2148938 (Clockwise)

Preceding gene: 41408044

Following gene: 41408046

Centisome position: 44.48

GC content: 75.05

Gene sequence:

>537_bases
GTGCGCACCCTGGTGCTCGGCGGGATCAGGTCAGGCAAGTCGCAGTGGGCGGAGGACGCCGTCGCCGACGGGCTGCCGGC
CGGCCGGCCGGTTCGTTACCTGGCGCCCGGGCCGCCCGGCGCGCACGATGCGGCCTGGGCGCACCGGGTCGCCGAGCATC
GCGACCGGCGGCCCGCGCACTGGTCGACGATCGAAACCGACGACATCGCAACCGAATTGCGCCGCTGTCCGCAGGTCCCC
ACCCTGGTCGACGACCTGGGCGGCTGGCTGACCGGCATGCTGGACCGGCACGACGGATGGCAGGGCGGCTCGGTGACCGC
CCCGGTCGACGACGTGCTGGCCGCGGTCGCCGAGTTCGCCGGCGCGCTGGTGCTGGTCAGCCCGGAGGTGGGGCTGACTG
TGGTGCCGGCCACCGCGTCCGCGCGCCGGTTCGCCGACGAGCTGGGCAGTCTCAACCAGCGCCTCGCGCGGCTGTGCGAC
CGGGTGGTGCTGGTGGTGGCCGGCCAGCCGGTGCCGATCAAAACGCCGGGGGTCTGA

Upstream 100 bases:

>100_bases
CGGCCGGGCCTCGCAGATGCGACGGTTGCGGGCGCCGCGACCCCAAGTCAAGCACGGCAGCAGTGTCGATTAGACCTCAC
CCGAAAGCCAGCTGACACCG

Downstream 100 bases:

>100_bases
TGGAATTCGCGACCGTCTCGCCGCCCGACCCGGGCACGGCCGCCGCCGCCCGGGCGCGGCAGGACACCCTGACCAAACCG
CGCGGCGCGCTAGGCCGGCT

Product: hypothetical protein

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MRTLVLGGIRSGKSQWAEDAVADGLPAGRPVRYLAPGPPGAHDAAWAHRVAEHRDRRPAHWSTIETDDIATELRRCPQVP
TLVDDLGGWLTGMLDRHDGWQGGSVTAPVDDVLAAVAEFAGALVLVSPEVGLTVVPATASARRFADELGSLNQRLARLCD
RVVLVVAGQPVPIKTPGV

Sequences:

>Translated_178_residues
MRTLVLGGIRSGKSQWAEDAVADGLPAGRPVRYLAPGPPGAHDAAWAHRVAEHRDRRPAHWSTIETDDIATELRRCPQVP
TLVDDLGGWLTGMLDRHDGWQGGSVTAPVDDVLAAVAEFAGALVLVSPEVGLTVVPATASARRFADELGSLNQRLARLCD
RVVLVVAGQPVPIKTPGV
>Mature_178_residues
MRTLVLGGIRSGKSQWAEDAVADGLPAGRPVRYLAPGPPGAHDAAWAHRVAEHRDRRPAHWSTIETDDIATELRRCPQVP
TLVDDLGGWLTGMLDRHDGWQGGSVTAPVDDVLAAVAEFAGALVLVSPEVGLTVVPATASARRFADELGSLNQRLARLCD
RVVLVVAGQPVPIKTPGV

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=187, Percent_Identity=33.6898395721925, Blast_Score=78, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 18871; Mature: 18871

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTLVLGGIRSGKSQWAEDAVADGLPAGRPVRYLAPGPPGAHDAAWAHRVAEHRDRRPAH
CCEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCC
WSTIETDDIATELRRCPQVPTLVDDLGGWLTGMLDRHDGWQGGSVTAPVDDVLAAVAEFA
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
GALVLVSPEVGLTVVPATASARRFADELGSLNQRLARLCDRVVLVVAGQPVPIKTPGV
CEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCC
>Mature Secondary Structure
MRTLVLGGIRSGKSQWAEDAVADGLPAGRPVRYLAPGPPGAHDAAWAHRVAEHRDRRPAH
CCEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCC
WSTIETDDIATELRRCPQVPTLVDDLGGWLTGMLDRHDGWQGGSVTAPVDDVLAAVAEFA
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
GALVLVSPEVGLTVVPATASARRFADELGSLNQRLARLCDRVVLVVAGQPVPIKTPGV
CEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]