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The map label for this gene is cobT

Identifier: 41408046

GI number: 41408046

Start: 2148938

End: 2149987

Strand: Direct

Name: cobT

Synonym: MAP1948

Alternate gene names: 41408046

Gene position: 2148938-2149987 (Clockwise)

Preceding gene: 41408045

Following gene: 41408047

Centisome position: 44.49

GC content: 75.52

Gene sequence:

>1050_bases
ATGGAATTCGCGACCGTCTCGCCGCCCGACCCGGGCACGGCCGCCGCCGCCCGGGCGCGGCAGGACACCCTGACCAAACC
GCGCGGCGCGCTAGGCCGGCTGGAGGACCTGTCGGTGTGGATCGCGGCCTGCCAGGGGCAGTGCCCGCCGCGGCAGTTCG
AGCGGGCCCGGGTGGTGGTGTTCGCCGGTGATCACGGCGTCGCCCGGTGCGGCGTCTCGGCCTACCCGCCGGAGGTGACG
GCCCAGATGGTCGCCAACTTCGACGCGGGCGGCGCCGCGATCAACGCGCTGGCCGGCGTCGCCGGGGCGAGCGTGCGCGT
GGCGGACCTGGCGGTGGACGCAGACCCGCCCGACGATCGGATCGGCGCGCACAAGGTCCGCCGCGGTAGCGGCGACATCA
CGGTGCAGGACGCGTTGACCGCTGAGGAGACCGAGCGGGCGCTGTCCGCGGGTGCGGCCATCGCCGACGAGGAGGTCGAC
GCCGGCGCGGACCTGCTGATCGCCGGCGACATGGGGATCGGAAACACCACGGCCGCAGCGGTATTGGTGGCGGCGCTGAC
CAACGTCGAGCCGGTCGTGGCGGTGGGGTTTGGCACCGGCATCGACGACGCCGGGTGGGCGCGGAAGACGGCCGCGGTGC
GCGACGCGCTTTTTCGGGCGCGACGGGTATTGCCCGACCCGGTCGCGCTGCTGCGCTGCGCCGGAGGCGCGGATCTGGCT
GCGCTGGCGGGTTTTTGCGCGCAGGCCGCGGTGCGGCGCACCCCGCTGCTGCTCGACGGCATGGCGGTGACGGCGGCCGC
GCTGGTCGCCGAGCACCTGGCGCCGGGCGCCCGGCTGTGGTGGCAGGCCGGGCACCGCTCCACCGAGCCGGGTCATGCGC
TGGCGCTGACCGCGCTGGATCTGGAGCCGATTCTCGACCTGCGCATGCGGCTCGGTGAGGGCACCGGCGCCGCGCTGGCG
CTGCCCATCGTGCGGGCCGCGGTGGCGGCCCTGTCGTCGATGGCGACCTTCGCCCAGGCCGGTGTGTCCGACCCGTCCGC
TCACCCGTGA

Upstream 100 bases:

>100_bases
ACGAGCTGGGCAGTCTCAACCAGCGCCTCGCGCGGCTGTGCGACCGGGTGGTGCTGGTGGTGGCCGGCCAGCCGGTGCCG
ATCAAAACGCCGGGGGTCTG

Downstream 100 bases:

>100_bases
TGCGTTCGCTGGCAACGGCTTTCGCGTTCGGCACGGTGCTGCCCGTGCCGGCAGGCGGCCGCGGGCCGATGGGCCGCGGC
GCCATGACGGCGCTGCCGGT

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MEFATVSPPDPGTAAAARARQDTLTKPRGALGRLEDLSVWIAACQGQCPPRQFERARVVVFAGDHGVARCGVSAYPPEVT
AQMVANFDAGGAAINALAGVAGASVRVADLAVDADPPDDRIGAHKVRRGSGDITVQDALTAEETERALSAGAAIADEEVD
AGADLLIAGDMGIGNTTAAAVLVAALTNVEPVVAVGFGTGIDDAGWARKTAAVRDALFRARRVLPDPVALLRCAGGADLA
ALAGFCAQAAVRRTPLLLDGMAVTAAALVAEHLAPGARLWWQAGHRSTEPGHALALTALDLEPILDLRMRLGEGTGAALA
LPIVRAAVAALSSMATFAQAGVSDPSAHP

Sequences:

>Translated_349_residues
MEFATVSPPDPGTAAAARARQDTLTKPRGALGRLEDLSVWIAACQGQCPPRQFERARVVVFAGDHGVARCGVSAYPPEVT
AQMVANFDAGGAAINALAGVAGASVRVADLAVDADPPDDRIGAHKVRRGSGDITVQDALTAEETERALSAGAAIADEEVD
AGADLLIAGDMGIGNTTAAAVLVAALTNVEPVVAVGFGTGIDDAGWARKTAAVRDALFRARRVLPDPVALLRCAGGADLA
ALAGFCAQAAVRRTPLLLDGMAVTAAALVAEHLAPGARLWWQAGHRSTEPGHALALTALDLEPILDLRMRLGEGTGAALA
LPIVRAAVAALSSMATFAQAGVSDPSAHP
>Mature_349_residues
MEFATVSPPDPGTAAAARARQDTLTKPRGALGRLEDLSVWIAACQGQCPPRQFERARVVVFAGDHGVARCGVSAYPPEVT
AQMVANFDAGGAAINALAGVAGASVRVADLAVDADPPDDRIGAHKVRRGSGDITVQDALTAEETERALSAGAAIADEEVD
AGADLLIAGDMGIGNTTAAAVLVAALTNVEPVVAVGFGTGIDDAGWARKTAAVRDALFRARRVLPDPVALLRCAGGADLA
ALAGFCAQAAVRRTPLLLDGMAVTAAALVAEHLAPGARLWWQAGHRSTEPGHALALTALDLEPILDLRMRLGEGTGAALA
LPIVRAAVAALSSMATFAQAGVSDPSAHP

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=335, Percent_Identity=36.4179104477612, Blast_Score=177, Evalue=7e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 35398; Mature: 35398

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFATVSPPDPGTAAAARARQDTLTKPRGALGRLEDLSVWIAACQGQCPPRQFERARVVV
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHCCCCCHHHHCCEEEEE
FAGDHGVARCGVSAYPPEVTAQMVANFDAGGAAINALAGVAGASVRVADLAVDADPPDDR
EECCCCHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCC
IGAHKVRRGSGDITVQDALTAEETERALSAGAAIADEEVDAGADLLIAGDMGIGNTTAAA
CCHHHHHCCCCCEEEEHHHHHHHHHHHHHHCCHHCCCCCCCCCCEEEECCCCCCCHHHHH
VLVAALTNVEPVVAVGFGTGIDDAGWARKTAAVRDALFRARRVLPDPVALLRCAGGADLA
HHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHH
ALAGFCAQAAVRRTPLLLDGMAVTAAALVAEHLAPGARLWWQAGHRSTEPGHALALTALD
HHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCEEEEEEEC
LEPILDLRMRLGEGTGAALALPIVRAAVAALSSMATFAQAGVSDPSAHP
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MEFATVSPPDPGTAAAARARQDTLTKPRGALGRLEDLSVWIAACQGQCPPRQFERARVVV
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHCCCCCHHHHCCEEEEE
FAGDHGVARCGVSAYPPEVTAQMVANFDAGGAAINALAGVAGASVRVADLAVDADPPDDR
EECCCCHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCC
IGAHKVRRGSGDITVQDALTAEETERALSAGAAIADEEVDAGADLLIAGDMGIGNTTAAA
CCHHHHHCCCCCEEEEHHHHHHHHHHHHHHCCHHCCCCCCCCCCEEEECCCCCCCHHHHH
VLVAALTNVEPVVAVGFGTGIDDAGWARKTAAVRDALFRARRVLPDPVALLRCAGGADLA
HHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHH
ALAGFCAQAAVRRTPLLLDGMAVTAAALVAEHLAPGARLWWQAGHRSTEPGHALALTALD
HHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCEEEEEEEC
LEPILDLRMRLGEGTGAALALPIVRAAVAALSSMATFAQAGVSDPSAHP
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA