| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
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The map label for this gene is ephD [H]
Identifier: 41407814
GI number: 41407814
Start: 1875600
End: 1876439
Strand: Direct
Name: ephD [H]
Synonym: MAP1716
Alternate gene names: 41407814
Gene position: 1875600-1876439 (Clockwise)
Preceding gene: 41407813
Following gene: 41407815
Centisome position: 38.83
GC content: 68.57
Gene sequence:
>840_bases ATGGATCTGACAGACAAGGTCGTCGCGATCACCGGCGGCGCACGCGGCATCGGGCTGGCGACGGCGAAAGCGTTCCTGGC AGCCGGCGCAAAGGTCGCCCTCGGTGACCTCGACACCGAACTCGCGGAGAAACAGGCCGTCGAACTCGGCGGCGATCCGG CGGTGGTCGGATTGTCGCTCGATGTCAGCGATCCCGCGTCATTCGTCGCATTCCTGGACGACGTCGAGGCCCGGCTGGGT CGGCTCGACGTGCTCGTCAGCAATGCCGGCATCATGCCGACCGGCCCGTTCGTCGACGAGCCGCCGACCATGAGCCGCCG CATGATCGACGTCAACGTCTACGGGGTGCTCAACGGGTCTCGGCTGGCGGCAGCGCGGTTCGTGCCCAGGGGAGCGGGAC ACATCGTCAACATCGCGTCGCTGGCCGGCGTCACCGGTGAGCCGGGAATGGCGACCTATTGCGGCACAAAGCATTTCGTG GTCGGCTTCACCGAATCGCTGCACCGCGAACTGCGCCCGCACCGCGTCGGGGTCAGCCTGGTGCTTCCGGGCATCATCAA CACCGAATTATCCGCGGGCACAAAGGTTCCCGGCTGGGCCAGGCCACTGGCCACCGCCGAGCCCGAGGACGTCGCCGCCG GTATCGTCGCCGCCGTCAGCAAAGACAAGCCACGCAAGACCGTGCCGGCCACCCTCGGCGCCCTGCTCAAGTCCGTCTCG CTGCTGCCCGACACGCCGCGTTTTGCCGTCGCGCACGCCGTCCGGTTCGACCAGCTCGTCAGCGGCGCCGACCCCAACGC CCGCGCCGCCTACCACCGGCGGCTGGCCGAGGAATCATGA
Upstream 100 bases:
>100_bases CCGGCGGAGTGCGCCAGTTCGTCACCGGCTATCCGGGCGGGATCGATGCGTTCCGCCGGCGCGCCGATGAACTCGCCGCA AGGTATGGAGGGCGATTCCG
Downstream 100 bases:
>100_bases CAGGGGCTGAAGAAGCGAATCTCGTGCAGCGGGTACCCGGCGAGCAGCGCTGAGGTTTACTCGGGTGCTCTGGCTTGCTG CCAGTGCTAGCGGCGTAAGT
Product: short chain dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 279; Mature: 279
Protein sequence:
>279_residues MDLTDKVVAITGGARGIGLATAKAFLAAGAKVALGDLDTELAEKQAVELGGDPAVVGLSLDVSDPASFVAFLDDVEARLG RLDVLVSNAGIMPTGPFVDEPPTMSRRMIDVNVYGVLNGSRLAAARFVPRGAGHIVNIASLAGVTGEPGMATYCGTKHFV VGFTESLHRELRPHRVGVSLVLPGIINTELSAGTKVPGWARPLATAEPEDVAAGIVAAVSKDKPRKTVPATLGALLKSVS LLPDTPRFAVAHAVRFDQLVSGADPNARAAYHRRLAEES
Sequences:
>Translated_279_residues MDLTDKVVAITGGARGIGLATAKAFLAAGAKVALGDLDTELAEKQAVELGGDPAVVGLSLDVSDPASFVAFLDDVEARLG RLDVLVSNAGIMPTGPFVDEPPTMSRRMIDVNVYGVLNGSRLAAARFVPRGAGHIVNIASLAGVTGEPGMATYCGTKHFV VGFTESLHRELRPHRVGVSLVLPGIINTELSAGTKVPGWARPLATAEPEDVAAGIVAAVSKDKPRKTVPATLGALLKSVS LLPDTPRFAVAHAVRFDQLVSGADPNARAAYHRRLAEES >Mature_279_residues MDLTDKVVAITGGARGIGLATAKAFLAAGAKVALGDLDTELAEKQAVELGGDPAVVGLSLDVSDPASFVAFLDDVEARLG RLDVLVSNAGIMPTGPFVDEPPTMSRRMIDVNVYGVLNGSRLAAARFVPRGAGHIVNIASLAGVTGEPGMATYCGTKHFV VGFTESLHRELRPHRVGVSLVLPGIINTELSAGTKVPGWARPLATAEPEDVAAGIVAAVSKDKPRKTVPATLGALLKSVS LLPDTPRFAVAHAVRFDQLVSGADPNARAAYHRRLAEES
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI20149619, Length=237, Percent_Identity=31.2236286919831, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI40254992, Length=191, Percent_Identity=30.8900523560209, Blast_Score=95, Evalue=8e-20, Organism=Homo sapiens, GI40807363, Length=244, Percent_Identity=29.0983606557377, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI31542939, Length=196, Percent_Identity=32.6530612244898, Blast_Score=89, Evalue=6e-18, Organism=Homo sapiens, GI142976729, Length=268, Percent_Identity=27.9850746268657, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI4503817, Length=247, Percent_Identity=28.7449392712551, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI7706318, Length=198, Percent_Identity=28.2828282828283, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI224922801, Length=172, Percent_Identity=33.1395348837209, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI4758504, Length=218, Percent_Identity=33.0275229357798, Blast_Score=83, Evalue=4e-16, Organism=Homo sapiens, GI310128830, Length=248, Percent_Identity=27.4193548387097, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI310115468, Length=248, Percent_Identity=27.4193548387097, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI210032110, Length=245, Percent_Identity=26.1224489795918, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI15277342, Length=231, Percent_Identity=31.6017316017316, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI83715985, Length=179, Percent_Identity=34.6368715083799, Blast_Score=75, Evalue=8e-14, Organism=Homo sapiens, GI109715829, Length=233, Percent_Identity=24.8927038626609, Blast_Score=75, Evalue=1e-13, Organism=Homo sapiens, GI25282469, Length=268, Percent_Identity=23.8805970149254, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI157739938, Length=192, Percent_Identity=27.0833333333333, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI7705925, Length=206, Percent_Identity=29.6116504854369, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI7705855, Length=279, Percent_Identity=26.1648745519713, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI59889578, Length=169, Percent_Identity=29.585798816568, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI166795268, Length=219, Percent_Identity=31.9634703196347, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI32483357, Length=198, Percent_Identity=28.2828282828283, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI150247226, Length=200, Percent_Identity=34, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI19743808, Length=198, Percent_Identity=32.8282828282828, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI40548397, Length=203, Percent_Identity=29.5566502463054, Blast_Score=65, Evalue=9e-11, Organism=Homo sapiens, GI214010158, Length=203, Percent_Identity=29.5566502463054, Blast_Score=65, Evalue=9e-11, Organism=Homo sapiens, GI214010156, Length=203, Percent_Identity=29.5566502463054, Blast_Score=65, Evalue=9e-11, Organism=Homo sapiens, GI22758144, Length=203, Percent_Identity=29.5566502463054, Blast_Score=65, Evalue=9e-11, Organism=Escherichia coli, GI1787335, Length=223, Percent_Identity=32.7354260089686, Blast_Score=100, Evalue=2e-22, Organism=Escherichia coli, GI87082100, Length=222, Percent_Identity=34.2342342342342, Blast_Score=100, Evalue=2e-22, Organism=Escherichia coli, GI87082160, Length=201, Percent_Identity=31.8407960199005, Blast_Score=87, Evalue=8e-19, Organism=Escherichia coli, GI1790717, Length=192, Percent_Identity=30.2083333333333, Blast_Score=84, Evalue=7e-18, Organism=Escherichia coli, GI1788459, Length=191, Percent_Identity=32.9842931937173, Blast_Score=78, Evalue=7e-16, Organism=Escherichia coli, GI1786812, Length=194, Percent_Identity=31.9587628865979, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1787820, Length=252, Percent_Identity=27.7777777777778, Blast_Score=73, Evalue=3e-14, Organism=Escherichia coli, GI2367175, Length=230, Percent_Identity=33.0434782608696, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI2367365, Length=191, Percent_Identity=32.9842931937173, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1786701, Length=237, Percent_Identity=26.5822784810127, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI1787905, Length=220, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1789208, Length=189, Percent_Identity=27.5132275132275, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1789378, Length=233, Percent_Identity=27.4678111587983, Blast_Score=61, Evalue=9e-11, Organism=Caenorhabditis elegans, GI17508895, Length=263, Percent_Identity=29.277566539924, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI193203115, Length=270, Percent_Identity=29.2592592592593, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI193203117, Length=267, Percent_Identity=28.4644194756554, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17564282, Length=246, Percent_Identity=29.2682926829268, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17567345, Length=259, Percent_Identity=27.027027027027, Blast_Score=94, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17555706, Length=190, Percent_Identity=33.6842105263158, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI25147288, Length=192, Percent_Identity=32.2916666666667, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17560676, Length=236, Percent_Identity=27.1186440677966, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI71994600, Length=189, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17561402, Length=190, Percent_Identity=28.4210526315789, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17538182, Length=267, Percent_Identity=29.5880149812734, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI71994604, Length=189, Percent_Identity=29.6296296296296, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71997402, Length=192, Percent_Identity=27.0833333333333, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17562908, Length=207, Percent_Identity=28.0193236714976, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI115534660, Length=193, Percent_Identity=31.6062176165803, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI193204405, Length=195, Percent_Identity=29.2307692307692, Blast_Score=64, Evalue=8e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=200, Percent_Identity=30.5, Blast_Score=84, Evalue=2e-17, Organism=Saccharomyces cerevisiae, GI6322067, Length=194, Percent_Identity=29.8969072164948, Blast_Score=79, Evalue=7e-16, Organism=Saccharomyces cerevisiae, GI6322861, Length=191, Percent_Identity=29.8429319371728, Blast_Score=74, Evalue=3e-14, Organism=Drosophila melanogaster, GI281364892, Length=252, Percent_Identity=32.5396825396825, Blast_Score=114, Evalue=5e-26, Organism=Drosophila melanogaster, GI24581726, Length=248, Percent_Identity=29.0322580645161, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI24640492, Length=249, Percent_Identity=28.9156626506024, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=32.8205128205128, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI24644339, Length=197, Percent_Identity=35.0253807106599, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI116007236, Length=226, Percent_Identity=29.646017699115, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI24580925, Length=219, Percent_Identity=31.9634703196347, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI17737361, Length=202, Percent_Identity=32.1782178217822, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI21357041, Length=193, Percent_Identity=32.6424870466321, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI116007234, Length=226, Percent_Identity=30.9734513274336, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI221510726, Length=247, Percent_Identity=28.7449392712551, Blast_Score=81, Evalue=9e-16, Organism=Drosophila melanogaster, GI21355631, Length=177, Percent_Identity=31.638418079096, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI28571526, Length=191, Percent_Identity=32.9842931937173, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI281364494, Length=227, Percent_Identity=28.1938325991189, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI24641232, Length=238, Percent_Identity=28.9915966386555, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI23397609, Length=190, Percent_Identity=31.5789473684211, Blast_Score=74, Evalue=8e-14, Organism=Drosophila melanogaster, GI21355319, Length=199, Percent_Identity=29.1457286432161, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24644337, Length=237, Percent_Identity=32.0675105485232, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI21356301, Length=243, Percent_Identity=28.3950617283951, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI116007238, Length=211, Percent_Identity=25.5924170616114, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI24663911, Length=199, Percent_Identity=30.6532663316583, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI24665243, Length=199, Percent_Identity=31.1557788944724, Blast_Score=71, Evalue=1e-12, Organism=Drosophila melanogaster, GI28571387, Length=208, Percent_Identity=27.4038461538462, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24656154, Length=241, Percent_Identity=30.7053941908714, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI19922628, Length=241, Percent_Identity=30.7053941908714, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24649181, Length=251, Percent_Identity=28.2868525896414, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI221331218, Length=199, Percent_Identity=31.1557788944724, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24665247, Length=200, Percent_Identity=31.5, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24640442, Length=190, Percent_Identity=30.5263157894737, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI116007232, Length=180, Percent_Identity=31.6666666666667, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24639444, Length=196, Percent_Identity=30.6122448979592, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI221331216, Length=200, Percent_Identity=31.5, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI24648693, Length=236, Percent_Identity=27.9661016949153, Blast_Score=68, Evalue=9e-12, Organism=Drosophila melanogaster, GI21355889, Length=236, Percent_Identity=27.9661016949153, Blast_Score=68, Evalue=9e-12, Organism=Drosophila melanogaster, GI24641388, Length=199, Percent_Identity=31.6582914572864, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24643142, Length=203, Percent_Identity=31.0344827586207, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000073 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00561 Abhydrolase_1; PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 28926; Mature: 28926
Theoretical pI: Translated: 6.80; Mature: 6.80
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDLTDKVVAITGGARGIGLATAKAFLAAGAKVALGDLDTELAEKQAVELGGDPAVVGLSL CCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCEEEEEEE DVSDPASFVAFLDDVEARLGRLDVLVSNAGIMPTGPFVDEPPTMSRRMIDVNVYGVLNGS CCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCC RLAAARFVPRGAGHIVNIASLAGVTGEPGMATYCGTKHFVVGFTESLHRELRPHRVGVSL CCHHHHHCCCCCCCEEEHHHHCCCCCCCCCEEECCCCEEEEECHHHHHHHCCCHHCCCEE VLPGIINTELSAGTKVPGWARPLATAEPEDVAAGIVAAVSKDKPRKTVPATLGALLKSVS EECCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH LLPDTPRFAVAHAVRFDQLVSGADPNARAAYHRRLAEES CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC >Mature Secondary Structure MDLTDKVVAITGGARGIGLATAKAFLAAGAKVALGDLDTELAEKQAVELGGDPAVVGLSL CCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCEEEEEEE DVSDPASFVAFLDDVEARLGRLDVLVSNAGIMPTGPFVDEPPTMSRRMIDVNVYGVLNGS CCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCC RLAAARFVPRGAGHIVNIASLAGVTGEPGMATYCGTKHFVVGFTESLHRELRPHRVGVSL CCHHHHHCCCCCCCEEEHHHHCCCCCCCCCEEECCCCEEEEECHHHHHHHCCCHHCCCEE VLPGIINTELSAGTKVPGWARPLATAEPEDVAAGIVAAVSKDKPRKTVPATLGALLKSVS EECCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH LLPDTPRFAVAHAVRFDQLVSGADPNARAAYHRRLAEES CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 12788972 [H]