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The map label for this gene is glnA3

Identifier: 41407697

GI number: 41407697

Start: 1755352

End: 1756704

Strand: Direct

Name: glnA3

Synonym: MAP1599

Alternate gene names: 41407697

Gene position: 1755352-1756704 (Clockwise)

Preceding gene: 41407696

Following gene: 41407698

Centisome position: 36.34

GC content: 71.03

Gene sequence:

>1353_bases
ATGACCGGCACACCGCTTGCCGCCGCGGCGATCGCCCAGCTGGAGGCCGAGGGCGTCGACACCGTGATCGGGACGGTCGT
CAATCCCGCCGGGCTCACCCTGGCCAAGACGGTTCCGATCCGGCGGACGAACACCTTCGCCGATCCGGGTCTGGGCGCCA
GCCCGTCCTGGCATGCCTTCGCCGTCGACCAAACCGGCATCGCGTTCACCGCCGAGGTGGGCGTGGTGGGGGACCAACGT
CTTCGGATCGACCTGTCCGCGTTGCGCATCGTCGGCGACGGCCTGGCCTGGGCGCCGGCCGCGTTTTTCGCCCAGGACGG
CACGCCCATACCCAGCTGCGCCCGCGGAACGCTGAAGCGGGTCGAGGCCGCGCTCGCCGACGCCGGCATCGACGCGGCCA
TCGGGCATGAGGTCGAATTCGTTCTGGTCGCCCCGGACGGGCAGCGGTTGCCGTCGACGTTGTGGGCGCAGTACGGCCTT
GCCGGGGTGCTGGAGCACGAGGCGTTCGTCCGCGATGTGATCGGTTCGGCGACCCGGGCCGGCATCGCGATCGAACAGCT
GCACCCCGAGTACGGCGCCAACCAGTTCGAGCTCTCGCTGGCGCCGCAACCCCCGGTGGCCGCCGCCGACCAGCTGATCT
TGATGCGGCTGATCATCGGCCGCGCGGCCCGCCGGCACGGGTTCCGCATCAGCCTGTCACCCGCACCGTTCGCCGGTGAT
GTGGGATCCGGTGCTCACCAACACTTTTCGCTGTCCATGGCGGAAGGGCCGCTGTTCTCCGGCGGCGCCGGCACGGCGGG
CATGACCCCGGCGGGGGAGAACGCGGTGGCGGGCGTGATCCGCGGGCTGCCCGAGGCGCAGGGTGTGCTGTGCGGGTCGA
TCGTCTCCGGCCTGCGGATACGCCCGGGCAATTGGGCCGGCGCCTACGCCTGCTGGGGGACCGAGAACCGGGAAGCCGCA
GTGCGATTCATCGTCGACGGCCCCGGCAGCCCGCGCGGCGGGAACGTCGAGGTGAAGATCGTCGATCCGTCGGCGAATCC
CTACCTGGCGTCGGCGGCCATCCTCGGGCTCTCCCTGGACGGTATCAAGTCGCAGGCGGCGCTGCCTCCCGAGGTCACGG
TCGACCCGGCGGCGCTGTCCGACGCCGACCGTGACCGCGACGGTGTGGTGCTGCTGACCGATTCGGCCGCAGAAGCGATT
GCGGCCCTTGATGATTCGGAGCTGATGCGGCACATCCTGGGCGACCCGGTGGTCGACATGGTGGTGGCGGTGCGCCGCTT
GGAGCAGGAACGCTACGGCGACCTGGACCCCGCGCAACTGGCGGACCGGTTCCGCATGGCCTGGAGCCTGTGA

Upstream 100 bases:

>100_bases
CGCCGTTGGACGGCTTTCTCGATCGGTTCGTCACCGAGTTGGTCGGCCGCCAGAACTGAAATCGCGGGCGCCGGGCCCGC
GACCCTGCACAATGACTGCC

Downstream 100 bases:

>100_bases
CGACGCCGCCATGGTCTCCGACACCGATGCCCTGGCCGAACACATCGGCGCCGTGTCGCTGATCGACCAGCACGTCCACG
GCTGCTGGCTGACGGCCGGC

Product: GlnA3

Products: NA

Alternate protein names: Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MTGTPLAAAAIAQLEAEGVDTVIGTVVNPAGLTLAKTVPIRRTNTFADPGLGASPSWHAFAVDQTGIAFTAEVGVVGDQR
LRIDLSALRIVGDGLAWAPAAFFAQDGTPIPSCARGTLKRVEAALADAGIDAAIGHEVEFVLVAPDGQRLPSTLWAQYGL
AGVLEHEAFVRDVIGSATRAGIAIEQLHPEYGANQFELSLAPQPPVAAADQLILMRLIIGRAARRHGFRISLSPAPFAGD
VGSGAHQHFSLSMAEGPLFSGGAGTAGMTPAGENAVAGVIRGLPEAQGVLCGSIVSGLRIRPGNWAGAYACWGTENREAA
VRFIVDGPGSPRGGNVEVKIVDPSANPYLASAAILGLSLDGIKSQAALPPEVTVDPAALSDADRDRDGVVLLTDSAAEAI
AALDDSELMRHILGDPVVDMVVAVRRLEQERYGDLDPAQLADRFRMAWSL

Sequences:

>Translated_450_residues
MTGTPLAAAAIAQLEAEGVDTVIGTVVNPAGLTLAKTVPIRRTNTFADPGLGASPSWHAFAVDQTGIAFTAEVGVVGDQR
LRIDLSALRIVGDGLAWAPAAFFAQDGTPIPSCARGTLKRVEAALADAGIDAAIGHEVEFVLVAPDGQRLPSTLWAQYGL
AGVLEHEAFVRDVIGSATRAGIAIEQLHPEYGANQFELSLAPQPPVAAADQLILMRLIIGRAARRHGFRISLSPAPFAGD
VGSGAHQHFSLSMAEGPLFSGGAGTAGMTPAGENAVAGVIRGLPEAQGVLCGSIVSGLRIRPGNWAGAYACWGTENREAA
VRFIVDGPGSPRGGNVEVKIVDPSANPYLASAAILGLSLDGIKSQAALPPEVTVDPAALSDADRDRDGVVLLTDSAAEAI
AALDDSELMRHILGDPVVDMVVAVRRLEQERYGDLDPAQLADRFRMAWSL
>Mature_449_residues
TGTPLAAAAIAQLEAEGVDTVIGTVVNPAGLTLAKTVPIRRTNTFADPGLGASPSWHAFAVDQTGIAFTAEVGVVGDQRL
RIDLSALRIVGDGLAWAPAAFFAQDGTPIPSCARGTLKRVEAALADAGIDAAIGHEVEFVLVAPDGQRLPSTLWAQYGLA
GVLEHEAFVRDVIGSATRAGIAIEQLHPEYGANQFELSLAPQPPVAAADQLILMRLIIGRAARRHGFRISLSPAPFAGDV
GSGAHQHFSLSMAEGPLFSGGAGTAGMTPAGENAVAGVIRGLPEAQGVLCGSIVSGLRIRPGNWAGAYACWGTENREAAV
RFIVDGPGSPRGGNVEVKIVDPSANPYLASAAILGLSLDGIKSQAALPPEVTVDPAALSDADRDRDGVVLLTDSAAEAIA
ALDDSELMRHILGDPVVDMVVAVRRLEQERYGDLDPAQLADRFRMAWSL

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=354, Percent_Identity=21.7514124293785, Blast_Score=73, Evalue=7e-13,
Organism=Escherichia coli, GI1790301, Length=257, Percent_Identity=29.9610894941634, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87081870, Length=290, Percent_Identity=27.9310344827586, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809
- InterPro:   IPR001637 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 46637; Mature: 46506

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGTPLAAAAIAQLEAEGVDTVIGTVVNPAGLTLAKTVPIRRTNTFADPGLGASPSWHAF
CCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEE
AVDQTGIAFTAEVGVVGDQRLRIDLSALRIVGDGLAWAPAAFFAQDGTPIPSCARGTLKR
EECCCCEEEEEEECCCCCCEEEEEHHHHHEECCCCHHCCHHHHCCCCCCCCHHHHHHHHH
VEAALADAGIDAAIGHEVEFVLVAPDGQRLPSTLWAQYGLAGVLEHEAFVRDVIGSATRA
HHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCHHHC
GIAIEQLHPEYGANQFELSLAPQPPVAAADQLILMRLIIGRAARRHGFRISLSPAPFAGD
CEEHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
VGSGAHQHFSLSMAEGPLFSGGAGTAGMTPAGENAVAGVIRGLPEAQGVLCGSIVSGLRI
CCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCEE
RPGNWAGAYACWGTENREAAVRFIVDGPGSPRGGNVEVKIVDPSANPYLASAAILGLSLD
CCCCCCCEEEEECCCCCCEEEEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHEEEEECC
GIKSQAALPPEVTVDPAALSDADRDRDGVVLLTDSAAEAIAALDDSELMRHILGDPVVDM
CCCCCCCCCCCCEECCHHCCCCCCCCCCEEEEECCHHHHHHHCCHHHHHHHHHCCHHHHH
VVAVRRLEQERYGDLDPAQLADRFRMAWSL
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TGTPLAAAAIAQLEAEGVDTVIGTVVNPAGLTLAKTVPIRRTNTFADPGLGASPSWHAF
CCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEE
AVDQTGIAFTAEVGVVGDQRLRIDLSALRIVGDGLAWAPAAFFAQDGTPIPSCARGTLKR
EECCCCEEEEEEECCCCCCEEEEEHHHHHEECCCCHHCCHHHHCCCCCCCCHHHHHHHHH
VEAALADAGIDAAIGHEVEFVLVAPDGQRLPSTLWAQYGLAGVLEHEAFVRDVIGSATRA
HHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCHHHC
GIAIEQLHPEYGANQFELSLAPQPPVAAADQLILMRLIIGRAARRHGFRISLSPAPFAGD
CEEHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
VGSGAHQHFSLSMAEGPLFSGGAGTAGMTPAGENAVAGVIRGLPEAQGVLCGSIVSGLRI
CCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCEE
RPGNWAGAYACWGTENREAAVRFIVDGPGSPRGGNVEVKIVDPSANPYLASAAILGLSLD
CCCCCCCEEEEECCCCCCEEEEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHEEEEECC
GIKSQAALPPEVTVDPAALSDADRDRDGVVLLTDSAAEAIAALDDSELMRHILGDPVVDM
CCCCCCCCCCCCEECCHHCCCCCCCCCCEEEEECCHHHHHHHCCHHHHHHHHHCCHHHHH
VVAVRRLEQERYGDLDPAQLADRFRMAWSL
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2572584 [H]