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The map label for this gene is iap [H]

Identifier: 41407301

GI number: 41407301

Start: 1263942

End: 1265354

Strand: Direct

Name: iap [H]

Synonym: MAP1203

Alternate gene names: 41407301

Gene position: 1263942-1265354 (Clockwise)

Preceding gene: 41407300

Following gene: 41407302

Centisome position: 26.17

GC content: 70.49

Gene sequence:

>1413_bases
ATGAGACGCACACGCTGGGGGACTTCCGCGCGGCCGGCCGCGAGGCTGGTTCGGCCCGTCGTGCCGTCGGTGTTGAGCGT
GGCCCTGCTGATCTGCACCCCGGGCCTGGCGCAGGCTGATCCCGTCGCCGACAACCTGGCCGCCCTGATCGCCAACGTCG
CCAAGGCCAACCAGCGCCTGCAGAACCTCAGCGCCGAAATCCAGACCGAGCAGGAAAGCGTCAACAAGGCGCTGGTCGAC
GTGGAGACCGCCCGGGACAACGCGGCCGCCGCCCAGCACGACCTGGAAGCCAGCCAGCAAGCGGTCAAGGACGCCAACGC
CGCCATCGCCGGCGCGCAGCGCCGCTTCGACACGTTTGCCGCGGCGGCCTACATGAACGGCCCGTCGAACAGCTACCTGA
CCGCACGCAACCCCGACGACATCATCGCCACCGAGGCCGCCGCCAAGACCCTGACCGCCAGCTCGCAGACGGTGATGGCC
AAACTGCAGCAGGCCCGCACCGAGCAGGTCAACAGGGAGTCGGCGGCGCGGCTGGCCAAGCAGAACGCCGACAAGGCCGC
CGCCGACGCCAAGGCCAGCCAGGACGCCGCGGTGGCCGCGCTGACCAACTCCCGGCAGAAGTTCGACGAGCAGCGCGAGC
AGATGATCCGGCTGGCCACCGAGCGGGACCAGGCCCAGGCCAAGCTGGAGGCGGCCAAACGTCAGCTGTCCACCGCGGGC
TCGGGCGACCGCTGGGAGACGGGATCGGCGGGCGCGCCGGCGCCGTCCGCGGGCCGGCAATGGGACGGCGCCTGGGACCC
CACCCTGCCGATGATTCCGAGCGCCAACGTTCCCGGCGACCCGATTGCGGTGATCAACCAGGTGCTGGGCATCTCGGCCA
CCTCGACCCAGGTCACCGCCGGTCTCGGCCGTAACTTCCTGCAGCAGCTCGGCATCCTCAAGCCCGACGACACCGGCATC
ACCAACGCGGCGCCCGGCGGGGTCGGGGCGCGCATCCCGCGGGTGTACGGGCGGCAGGCGACGGAGTACGTGATCCGTCG
CGGCATGTCGCAGATCGGGGTGCCCTACTCCTGGGGCGGCGGCAACGCGGCCGGCCCCAGCAAGGGCATCGACTCCGGCG
CCAACATCGTCGGCTTCGACTGTTCGGGGCTGGTGCTGTATTCGTTCGCCGGGGTGGGCATCAAGCTGCCGCACTACTCG
GGCTCGCAGTACAACCTGGGCCGCAAGATCCCGTCCTCGCAGATGCGCCGCGGCGACGTCATCTTCTACGGACCGGGCGG
CTCCCAGCACGTCACCATCTACCTCGGCGACGGCCAGATGCTCGAGGCGCCCGATATCGGGTTGAAGGTCCGCGTCGCCC
CCGTCCGCACCAGCGGCATGACGCCCTACGTGGTCCGTTACATCGAGTGGTGA

Upstream 100 bases:

>100_bases
GACGTACGGTGCAAATGATGCTGGTGTTGTCTTTGGTGCCTAACGATTATTCCGTGGTCGGCGCCACCCGTTGCGTTGAG
CCGTAGGAGACCTGAGTCGA

Downstream 100 bases:

>100_bases
GCAAGTGAGCAGTGAACGAGGAGCCATGCGCCGCAACCGGTTTCGTCTCATCGTCTTCGCCTGGATCACCGCGATGGTGA
CCGGGCTGATGTTTTCCGTG

Product: hypothetical protein

Products: NA

Alternate protein names: Invasion-associated protein [H]

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MRRTRWGTSARPAARLVRPVVPSVLSVALLICTPGLAQADPVADNLAALIANVAKANQRLQNLSAEIQTEQESVNKALVD
VETARDNAAAAQHDLEASQQAVKDANAAIAGAQRRFDTFAAAAYMNGPSNSYLTARNPDDIIATEAAAKTLTASSQTVMA
KLQQARTEQVNRESAARLAKQNADKAAADAKASQDAAVAALTNSRQKFDEQREQMIRLATERDQAQAKLEAAKRQLSTAG
SGDRWETGSAGAPAPSAGRQWDGAWDPTLPMIPSANVPGDPIAVINQVLGISATSTQVTAGLGRNFLQQLGILKPDDTGI
TNAAPGGVGARIPRVYGRQATEYVIRRGMSQIGVPYSWGGGNAAGPSKGIDSGANIVGFDCSGLVLYSFAGVGIKLPHYS
GSQYNLGRKIPSSQMRRGDVIFYGPGGSQHVTIYLGDGQMLEAPDIGLKVRVAPVRTSGMTPYVVRYIEW

Sequences:

>Translated_470_residues
MRRTRWGTSARPAARLVRPVVPSVLSVALLICTPGLAQADPVADNLAALIANVAKANQRLQNLSAEIQTEQESVNKALVD
VETARDNAAAAQHDLEASQQAVKDANAAIAGAQRRFDTFAAAAYMNGPSNSYLTARNPDDIIATEAAAKTLTASSQTVMA
KLQQARTEQVNRESAARLAKQNADKAAADAKASQDAAVAALTNSRQKFDEQREQMIRLATERDQAQAKLEAAKRQLSTAG
SGDRWETGSAGAPAPSAGRQWDGAWDPTLPMIPSANVPGDPIAVINQVLGISATSTQVTAGLGRNFLQQLGILKPDDTGI
TNAAPGGVGARIPRVYGRQATEYVIRRGMSQIGVPYSWGGGNAAGPSKGIDSGANIVGFDCSGLVLYSFAGVGIKLPHYS
GSQYNLGRKIPSSQMRRGDVIFYGPGGSQHVTIYLGDGQMLEAPDIGLKVRVAPVRTSGMTPYVVRYIEW
>Mature_470_residues
MRRTRWGTSARPAARLVRPVVPSVLSVALLICTPGLAQADPVADNLAALIANVAKANQRLQNLSAEIQTEQESVNKALVD
VETARDNAAAAQHDLEASQQAVKDANAAIAGAQRRFDTFAAAAYMNGPSNSYLTARNPDDIIATEAAAKTLTASSQTVMA
KLQQARTEQVNRESAARLAKQNADKAAADAKASQDAAVAALTNSRQKFDEQREQMIRLATERDQAQAKLEAAKRQLSTAG
SGDRWETGSAGAPAPSAGRQWDGAWDPTLPMIPSANVPGDPIAVINQVLGISATSTQVTAGLGRNFLQQLGILKPDDTGI
TNAAPGGVGARIPRVYGRQATEYVIRRGMSQIGVPYSWGGGNAAGPSKGIDSGANIVGFDCSGLVLYSFAGVGIKLPHYS
GSQYNLGRKIPSSQMRRGDVIFYGPGGSQHVTIYLGDGQMLEAPDIGLKVRVAPVRTSGMTPYVVRYIEW

Specific function: This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1787944, Length=148, Percent_Identity=30.4054054054054, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786421, Length=119, Percent_Identity=36.1344537815126, Blast_Score=79, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR003646
- InterPro:   IPR013247 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60; PF08239 SH3_3 [H]

EC number: NA

Molecular weight: Translated: 49603; Mature: 49603

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRTRWGTSARPAARLVRPVVPSVLSVALLICTPGLAQADPVADNLAALIANVAKANQRL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QNLSAEIQTEQESVNKALVDVETARDNAAAAQHDLEASQQAVKDANAAIAGAQRRFDTFA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAAYMNGPSNSYLTARNPDDIIATEAAAKTLTASSQTVMAKLQQARTEQVNRESAARLAK
HHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QNADKAAADAKASQDAAVAALTNSRQKFDEQREQMIRLATERDQAQAKLEAAKRQLSTAG
HCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SGDRWETGSAGAPAPSAGRQWDGAWDPTLPMIPSANVPGDPIAVINQVLGISATSTQVTA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHH
GLGRNFLQQLGILKPDDTGITNAAPGGVGARIPRVYGRQATEYVIRRGMSQIGVPYSWGG
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHCCHHHHCCCEECCC
GNAAGPSKGIDSGANIVGFDCSGLVLYSFAGVGIKLPHYSGSQYNLGRKIPSSQMRRGDV
CCCCCCCCCCCCCCCEEEECCCCHHHHHHCCCCEECCCCCCCCCCCCCCCCHHHHCCCCE
IFYGPGGSQHVTIYLGDGQMLEAPDIGLKVRVAPVRTSGMTPYVVRYIEW
EEECCCCCCEEEEEECCCCEEECCCCCEEEEEEEECCCCCCHHHHEEECC
>Mature Secondary Structure
MRRTRWGTSARPAARLVRPVVPSVLSVALLICTPGLAQADPVADNLAALIANVAKANQRL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QNLSAEIQTEQESVNKALVDVETARDNAAAAQHDLEASQQAVKDANAAIAGAQRRFDTFA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAAYMNGPSNSYLTARNPDDIIATEAAAKTLTASSQTVMAKLQQARTEQVNRESAARLAK
HHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QNADKAAADAKASQDAAVAALTNSRQKFDEQREQMIRLATERDQAQAKLEAAKRQLSTAG
HCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SGDRWETGSAGAPAPSAGRQWDGAWDPTLPMIPSANVPGDPIAVINQVLGISATSTQVTA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHH
GLGRNFLQQLGILKPDDTGITNAAPGGVGARIPRVYGRQATEYVIRRGMSQIGVPYSWGG
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHCCHHHHCCCEECCC
GNAAGPSKGIDSGANIVGFDCSGLVLYSFAGVGIKLPHYSGSQYNLGRKIPSSQMRRGDV
CCCCCCCCCCCCCCCEEEECCCCHHHHHHCCCCEECCCCCCCCCCCCCCCCHHHHCCCCE
IFYGPGGSQHVTIYLGDGQMLEAPDIGLKVRVAPVRTSGMTPYVVRYIEW
EEECCCCCCEEEEEECCCCEEECCCCCEEEEEEEECCCCCCHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2111287; 1459966; 11679669 [H]