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The map label for this gene is pgk

Identifier: 41407263

GI number: 41407263

Start: 1222923

End: 1224170

Strand: Direct

Name: pgk

Synonym: MAP1165

Alternate gene names: 41407263

Gene position: 1222923-1224170 (Clockwise)

Preceding gene: 41407262

Following gene: 41407264

Centisome position: 25.32

GC content: 70.51

Gene sequence:

>1248_bases
GTGGCTGTCCACAATCTCAAAGACCTTCTCGCCGAAGGTGTTTCCGGACGCGGTGTGCTGGTGCGTTCGGACCTGAACGT
GCCGCTGGACTCCGATGGTGAGCAAGGCCGGATCACCGACCCCGGCCGCATCACCGCGTCGGTGCCGACGTTGAGCGCAC
TGGTCGAGGCGGGCGCCAAGGTGGTGGTCGCCGCGCACCTCGGGCGTCCCAAGAACGGGCCGGACCCGGCGTTGTCGCTG
GCCCCGGTGGCCGCCGCGCTCGGCGAGCAGCTGGGCCGGCACGTGCAGCTGGCCTCGGACGTGGTGGGCACCGACGCCCT
GGCCCGCGCCGAGGGGTTGACCGACGGCGACGTCCTGCTGCTGGAAAACATCCGGTTCGACGCCCGCGAAACGTCCAAGG
ACGACGCCGAGCGGCTCGCGCTGGCCCGGCAGCTGGCCGAATTGGTCGGTCCCACAGGCGCTTTCGTCTCCGACGGTTTC
GGCGTGGTGCACCGCAAGCAGGCCTCGGTGTACGACGTCGCCACGCTGCTGCCGCACTACGCCGGCACGCTGGTGGCCGA
GGAGATCGCCGTGCTGGAGCAGCTGACCGGCTCCACCAAACGCCCCTACGCGGTGGTGCTCGGCGGGTCCAAGGTGTCCG
ACAAGCTCGGCGTCATCGAGTCGCTGGCCACCAAGGCCGACAGCATCGTCATCGGCGGCGGCATGTGCTTCACCTTCCTT
GCCGCGCAAGGGTTTTCGGTTGGCAAGTCGCTGCTGGAAACCGAGATGGTGGACACCTGCCGCCGGCTGCTGGACACCTA
CGTCGACGTGCTGCGGCTGCCGGTGGACATCGTGGCGGCCGACAGGTTCGCCGCCGACGCGGCGCCGCAGACCGTGCCGG
CCGACGCCATCCCCGACGACCTGATGGGCCTGGACATCGGGCCGGGATCGGTCAAGCGGTTCACCGCGCTGCTGTCCAAC
GCCGAGACGATCTTCTGGAACGGCCCGATGGGCGTGTTCGAGTTCCCGGCGTTCGCCGCGGGCACCAAGGGGCTGGCCGA
AGCGATCGCCGCGGCGACCGGCAAGGGCGCCTTCTCCGTGGTCGGCGGCGGCGACTCGGCGGCCGCGGTGCGCGCGCTGG
GCATCCCGGAGAGCGGCTTCTCGCACATTTCCACCGGCGGCGGGGCGTCGCTGGAATACCTTGAGGGCAAGGCACTTCCG
GGCATCGAGGTGCTGGGACGTCCGCAACCGACGGGAGGCGCCGCGTGA

Upstream 100 bases:

>100_bases
CGACAACCAAGCCAAGGTGGTGTCCTGGTACGACAACGAGTGGGGCTACTCCAACCGCCTCGTCGACCTGGTCGCCCTGG
TCGGCAAGTCGCTGTAAGCC

Downstream 100 bases:

>100_bases
GCCGCAAGCCGCTGATCGCCGGCAACTGGAAGATGAACCTCAACCACTTCGAGGCCATCGCGCTGGTGCAAAAGATCGCG
TTCGCGCTGCCGGACAAGTA

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MAVHNLKDLLAEGVSGRGVLVRSDLNVPLDSDGEQGRITDPGRITASVPTLSALVEAGAKVVVAAHLGRPKNGPDPALSL
APVAAALGEQLGRHVQLASDVVGTDALARAEGLTDGDVLLLENIRFDARETSKDDAERLALARQLAELVGPTGAFVSDGF
GVVHRKQASVYDVATLLPHYAGTLVAEEIAVLEQLTGSTKRPYAVVLGGSKVSDKLGVIESLATKADSIVIGGGMCFTFL
AAQGFSVGKSLLETEMVDTCRRLLDTYVDVLRLPVDIVAADRFAADAAPQTVPADAIPDDLMGLDIGPGSVKRFTALLSN
AETIFWNGPMGVFEFPAFAAGTKGLAEAIAAATGKGAFSVVGGGDSAAAVRALGIPESGFSHISTGGGASLEYLEGKALP
GIEVLGRPQPTGGAA

Sequences:

>Translated_415_residues
MAVHNLKDLLAEGVSGRGVLVRSDLNVPLDSDGEQGRITDPGRITASVPTLSALVEAGAKVVVAAHLGRPKNGPDPALSL
APVAAALGEQLGRHVQLASDVVGTDALARAEGLTDGDVLLLENIRFDARETSKDDAERLALARQLAELVGPTGAFVSDGF
GVVHRKQASVYDVATLLPHYAGTLVAEEIAVLEQLTGSTKRPYAVVLGGSKVSDKLGVIESLATKADSIVIGGGMCFTFL
AAQGFSVGKSLLETEMVDTCRRLLDTYVDVLRLPVDIVAADRFAADAAPQTVPADAIPDDLMGLDIGPGSVKRFTALLSN
AETIFWNGPMGVFEFPAFAAGTKGLAEAIAAATGKGAFSVVGGGDSAAAVRALGIPESGFSHISTGGGASLEYLEGKALP
GIEVLGRPQPTGGAA
>Mature_414_residues
AVHNLKDLLAEGVSGRGVLVRSDLNVPLDSDGEQGRITDPGRITASVPTLSALVEAGAKVVVAAHLGRPKNGPDPALSLA
PVAAALGEQLGRHVQLASDVVGTDALARAEGLTDGDVLLLENIRFDARETSKDDAERLALARQLAELVGPTGAFVSDGFG
VVHRKQASVYDVATLLPHYAGTLVAEEIAVLEQLTGSTKRPYAVVLGGSKVSDKLGVIESLATKADSIVIGGGMCFTFLA
AQGFSVGKSLLETEMVDTCRRLLDTYVDVLRLPVDIVAADRFAADAAPQTVPADAIPDDLMGLDIGPGSVKRFTALLSNA
ETIFWNGPMGVFEFPAFAAGTKGLAEAIAAATGKGAFSVVGGGDSAAAVRALGIPESGFSHISTGGGASLEYLEGKALPG
IEVLGRPQPTGGAA

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family

Homologues:

Organism=Homo sapiens, GI4505763, Length=421, Percent_Identity=38.479809976247, Blast_Score=259, Evalue=2e-69,
Organism=Homo sapiens, GI31543397, Length=408, Percent_Identity=38.9705882352941, Blast_Score=253, Evalue=3e-67,
Organism=Escherichia coli, GI1789294, Length=409, Percent_Identity=40.8312958435208, Blast_Score=266, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI17508823, Length=411, Percent_Identity=40.3892944038929, Blast_Score=276, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6319857, Length=408, Percent_Identity=38.7254901960784, Blast_Score=256, Evalue=5e-69,
Organism=Drosophila melanogaster, GI17136394, Length=409, Percent_Identity=39.3643031784841, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24581203, Length=414, Percent_Identity=37.9227053140097, Blast_Score=247, Evalue=9e-66,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): PGK_MYCA1 (A0QHY4)

Other databases:

- EMBL:   CP000479
- RefSeq:   YP_882522.1
- ProteinModelPortal:   A0QHY4
- SMR:   A0QHY4
- STRING:   A0QHY4
- EnsemblBacteria:   EBMYCT00000010719
- GeneID:   4530496
- GenomeReviews:   CP000479_GR
- KEGG:   mav:MAV_3340
- TIGR:   MAV_3340
- eggNOG:   COG0126
- GeneTree:   EBGT00050000017271
- HOGENOM:   HBG453500
- OMA:   STYGIAQ
- ProtClustDB:   PRK00073
- BioCyc:   MAVI243243:MAV_3340-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00145
- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824
- Gene3D:   G3DSA:3.40.50.1270
- Gene3D:   G3DSA:3.40.50.1260
- PANTHER:   PTHR11406
- PIRSF:   PIRSF000724
- PRINTS:   PR00477

Pfam domain/function: PF00162 PGK; SSF53748 PGK

EC number: =2.7.2.3

Molecular weight: Translated: 42438; Mature: 42306

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: BINDING 43-43 BINDING 125-125 BINDING 165-165 BINDING 215-215 BINDING 303-303 BINDING 334-334

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVHNLKDLLAEGVSGRGVLVRSDLNVPLDSDGEQGRITDPGRITASVPTLSALVEAGAK
CCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHCCCE
VVVAAHLGRPKNGPDPALSLAPVAAALGEQLGRHVQLASDVVGTDALARAEGLTDGDVLL
EEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCEEE
LENIRFDARETSKDDAERLALARQLAELVGPTGAFVSDGFGVVHRKQASVYDVATLLPHY
EECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCEEECCCHHHHHHHHHHHH
AGTLVAEEIAVLEQLTGSTKRPYAVVLGGSKVSDKLGVIESLATKADSIVIGGGMCFTFL
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEECCHHHHHHH
AAQGFSVGKSLLETEMVDTCRRLLDTYVDVLRLPVDIVAADRFAADAAPQTVPADAIPDD
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCHH
LMGLDIGPGSVKRFTALLSNAETIFWNGPMGVFEFPAFAAGTKGLAEAIAAATGKGAFSV
HHCCCCCCCHHHHHHHHHCCCCEEEECCCCCHHHCCCHHCCHHHHHHHHHHHCCCCCEEE
VGGGDSAAAVRALGIPESGFSHISTGGGASLEYLEGKALPGIEVLGRPQPTGGAA
ECCCCCHHHEEEECCCCCCCCCCCCCCCCCCHHHCCCCCCCHHCCCCCCCCCCCC
>Mature Secondary Structure 
AVHNLKDLLAEGVSGRGVLVRSDLNVPLDSDGEQGRITDPGRITASVPTLSALVEAGAK
CCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHCCCE
VVVAAHLGRPKNGPDPALSLAPVAAALGEQLGRHVQLASDVVGTDALARAEGLTDGDVLL
EEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCEEE
LENIRFDARETSKDDAERLALARQLAELVGPTGAFVSDGFGVVHRKQASVYDVATLLPHY
EECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCEEECCCHHHHHHHHHHHH
AGTLVAEEIAVLEQLTGSTKRPYAVVLGGSKVSDKLGVIESLATKADSIVIGGGMCFTFL
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEECCHHHHHHH
AAQGFSVGKSLLETEMVDTCRRLLDTYVDVLRLPVDIVAADRFAADAAPQTVPADAIPDD
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCHH
LMGLDIGPGSVKRFTALLSNAETIFWNGPMGVFEFPAFAAGTKGLAEAIAAATGKGAFSV
HHCCCCCCCHHHHHHHHHCCCCEEEECCCCCHHHCCCHHCCHHHHHHHHHHHCCCCCEEE
VGGGDSAAAVRALGIPESGFSHISTGGGASLEYLEGKALPGIEVLGRPQPTGGAA
ECCCCCHHHEEEECCCCCCCCCCCCCCCCCCHHHCCCCCCCHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA