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The map label for this gene is ribG

Identifier: 41407234

GI number: 41407234

Start: 1190511

End: 1191536

Strand: Direct

Name: ribG

Synonym: MAP1136

Alternate gene names: 41407234

Gene position: 1190511-1191536 (Clockwise)

Preceding gene: 41407233

Following gene: 41407237

Centisome position: 24.65

GC content: 73.68

Gene sequence:

>1026_bases
ATGACCGCGTCGCTGGGCGACCGCCTGGACGCCGCGATGCACCTGGCGATCGAACAGTCCAATCAGGTCAAGGGCAACAC
CTATCCCAACCCGCCGGTGGGCGCGGTCGTCCTGGACGGCCGCGGCGAGGTGGTCGGCGTCGGCGGCACCGAACCGGCCG
GTGGCGACCACGCCGAGATCCTGGCGCTGCGCCGCGCCGGCGACCTGGCCGCCGGCGGAACCGTCGTCGTCACCCTCGAG
CCGTGCAACCACCACGGCAAGACGCCGCCGTGCGTGGACGCGCTGCTGGAGGCCGGGGTGGGCACGGTGGTCTACGCCGT
CGCCGACCCGAACCCGCAGGCCGCCGGCGGCGCCGGTCGGCTCCAGGAGGCGGGCGTGACGGTGCGCTCCGGGCTGCTGG
CCGACGAGGTGTCCGGCGGCCCGCTGCGGGAGTGGCTGCACAAGCAGCGCACCGGGCTGCCGCATCTGACCTGGAAATAC
GCCAGCAGCGTCGACGGGCGCAGCGCGGCCGCCGACGGGTCCAGCCGATGGATTTCCAGCGAGGCCTCGCGGCTGGACCT
GCACCGCCGCCGCGCGGCCGCCGACGCGATCGTGGTGGGTACCGGCACGGTGCTGGCCGACGACCCGGCGTTGACCGCCC
GGCTGCCCGACGGCACGCTGGCCGACCGGCAGCCGCTGCGGGTGGTCGTGGGGATGCGTGAAATACTTTCGGAGGCAAAG
GTTCTCAACGAAGAGTCGCGGACCATGGTGATCCGCACGCATGATCCCGCCGAGGTGCTCAAGGCGGTGTCGGACCGCAC
CGACGTCCTGCTGGAGGGCGGCCCCACCCTGGCCGGCGCGTTCGTGCGGGCGGGGCTGGTGAACCGGATCCTGGTCTACC
TCGCGCCCACCCTGCTGGGTGGCCCGGTCACCGCGGTCGACGACGTCGGGGTGCCGACGATCGCGAAGGCGCTGCGCTGG
CAGTTCGACGGGGTCGACCGGGTGGGCCCCGACCTGCTGCTCAGCCTGGTACCGCGCAGCGGCTAA

Upstream 100 bases:

>100_bases
GCTTCGTCGCCGGGTTGGCCGTGTACGGCGCCGACGACCCGGCCGCAGCGGTCGAGGCGCTGCGCCGGCAGGCCCTGGGC
GCGTCCCAGCACCTGCGTCG

Downstream 100 bases:

>100_bases
CGCTCACCCAGCGAGACCGCTTGCGGCTCAACGATTTCCGGTTCCTCGGCGTGTTCCTTGCGGCCGCCGATCAACAGGCC
CAGCAGCGCACCGGCGATGC

Product: RibG

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MTASLGDRLDAAMHLAIEQSNQVKGNTYPNPPVGAVVLDGRGEVVGVGGTEPAGGDHAEILALRRAGDLAAGGTVVVTLE
PCNHHGKTPPCVDALLEAGVGTVVYAVADPNPQAAGGAGRLQEAGVTVRSGLLADEVSGGPLREWLHKQRTGLPHLTWKY
ASSVDGRSAAADGSSRWISSEASRLDLHRRRAAADAIVVGTGTVLADDPALTARLPDGTLADRQPLRVVVGMREILSEAK
VLNEESRTMVIRTHDPAEVLKAVSDRTDVLLEGGPTLAGAFVRAGLVNRILVYLAPTLLGGPVTAVDDVGVPTIAKALRW
QFDGVDRVGPDLLLSLVPRSG

Sequences:

>Translated_341_residues
MTASLGDRLDAAMHLAIEQSNQVKGNTYPNPPVGAVVLDGRGEVVGVGGTEPAGGDHAEILALRRAGDLAAGGTVVVTLE
PCNHHGKTPPCVDALLEAGVGTVVYAVADPNPQAAGGAGRLQEAGVTVRSGLLADEVSGGPLREWLHKQRTGLPHLTWKY
ASSVDGRSAAADGSSRWISSEASRLDLHRRRAAADAIVVGTGTVLADDPALTARLPDGTLADRQPLRVVVGMREILSEAK
VLNEESRTMVIRTHDPAEVLKAVSDRTDVLLEGGPTLAGAFVRAGLVNRILVYLAPTLLGGPVTAVDDVGVPTIAKALRW
QFDGVDRVGPDLLLSLVPRSG
>Mature_340_residues
TASLGDRLDAAMHLAIEQSNQVKGNTYPNPPVGAVVLDGRGEVVGVGGTEPAGGDHAEILALRRAGDLAAGGTVVVTLEP
CNHHGKTPPCVDALLEAGVGTVVYAVADPNPQAAGGAGRLQEAGVTVRSGLLADEVSGGPLREWLHKQRTGLPHLTWKYA
SSVDGRSAAADGSSRWISSEASRLDLHRRRAAADAIVVGTGTVLADDPALTARLPDGTLADRQPLRVVVGMREILSEAKV
LNEESRTMVIRTHDPAEVLKAVSDRTDVLLEGGPTLAGAFVRAGLVNRILVYLAPTLLGGPVTAVDDVGVPTIAKALRWQ
FDGVDRVGPDLLLSLVPRSG

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=369, Percent_Identity=38.7533875338753, Blast_Score=229, Evalue=1e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 35399; Mature: 35267

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASLGDRLDAAMHLAIEQSNQVKGNTYPNPPVGAVVLDGRGEVVGVGGTEPAGGDHAEI
CCCCCCHHHHHHHEEEEECCCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCHHHE
LALRRAGDLAAGGTVVVTLEPCNHHGKTPPCVDALLEAGVGTVVYAVADPNPQAAGGAGR
EEEHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCC
LQEAGVTVRSGLLADEVSGGPLREWLHKQRTGLPHLTWKYASSVDGRSAAADGSSRWISS
HHHCCCHHHHCCHHHCCCCCHHHHHHHHHHCCCCCEEEHHHCCCCCCCCCCCCCCHHHHH
EASRLDLHRRRAAADAIVVGTGTVLADDPALTARLPDGTLADRQPLRVVVGMREILSEAK
HHHHHHHHHHHHHCCEEEEECCEEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
VLNEESRTMVIRTHDPAEVLKAVSDRTDVLLEGGPTLAGAFVRAGLVNRILVYLAPTLLG
HCCCCCCEEEEEECCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
GPVTAVDDVGVPTIAKALRWQFDGVDRVGPDLLLSLVPRSG
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure 
TASLGDRLDAAMHLAIEQSNQVKGNTYPNPPVGAVVLDGRGEVVGVGGTEPAGGDHAEI
CCCCCHHHHHHHEEEEECCCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCHHHE
LALRRAGDLAAGGTVVVTLEPCNHHGKTPPCVDALLEAGVGTVVYAVADPNPQAAGGAGR
EEEHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCC
LQEAGVTVRSGLLADEVSGGPLREWLHKQRTGLPHLTWKYASSVDGRSAAADGSSRWISS
HHHCCCHHHHCCHHHCCCCCHHHHHHHHHHCCCCCEEEHHHCCCCCCCCCCCCCCHHHHH
EASRLDLHRRRAAADAIVVGTGTVLADDPALTARLPDGTLADRQPLRVVVGMREILSEAK
HHHHHHHHHHHHHCCEEEEECCEEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
VLNEESRTMVIRTHDPAEVLKAVSDRTDVLLEGGPTLAGAFVRAGLVNRILVYLAPTLLG
HCCCCCCEEEEEECCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
GPVTAVDDVGVPTIAKALRWQFDGVDRVGPDLLLSLVPRSG
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]