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The map label for this gene is ribC

Identifier: 41407237

GI number: 41407237

Start: 1193912

End: 1194511

Strand: Direct

Name: ribC

Synonym: MAP1139

Alternate gene names: 41407237

Gene position: 1193912-1194511 (Clockwise)

Preceding gene: 41407234

Following gene: 41407238

Centisome position: 24.72

GC content: 71.17

Gene sequence:

>600_bases
ATGTTTACCGGAATTGTCGAGGAGCTCGGCGAGGTGACCGCCCGCGACGTGCTCGCCGATGCGGCGCGGCTGACCATCCG
CGGGGCCGTGGTGACCGCCGACGCCGGGCACGGCGATTCGATCGCCGTCAACGGTGTCTGCCTGACCGTCGCCGAGCTGC
TGCCCGACGGCCGGTTCAGCGCCGATGTGATGGGCGAGACGCTGAACCGGTCCAACCTGGGCGCGCTGCAGGTCGGCAGC
CGGGTGAACCTGGAACGCGCGGCCGCCGTCAACAGCCGGCTGGGCGGGCACATCGTGCAGGGTCACGTCGACGGCACCGG
GCGGATCGTGGCGCGCACCCCGTCCGAGCACTGGGAGGTGGTGCGCATCGAGGTGCCGCCGGAGGTGGCCCGCTACGTGG
TGGAGAAGGGGTCGATCACGGTCGACGGCATCTCGCTGACGGTGTCCGGGCTGGGCGGCGAGCCCCGCGACTGGTTCGAG
GTGTCGCTGATCCCCACCACCCGGGAGCTGACCACGCTGGGCGGCGCCCCGGTGGGGACGCAGGTCAATCTCGAGGTCGA
CGTGATCGCCAAGTACGTCGAGCGGCTGATGTCCCGCTGA

Upstream 100 bases:

>100_bases
TGCCGGTGACTGCCCTGGTGAACGCGGGGGGCCGGTGTCTCACAGGCGGCGGTGTTTGCCCTGCTCACCAGCCTGAGCGG
GGGCGAATTAGCCTGGGGGG

Downstream 100 bases:

>100_bases
TCAAGCCATGGCAATAACCGCGGCGCCGCCGTGGTTCATACTGAATGCAACACGTGGGCTTCTCGTGTGAGCCGTTTCTA
CAGTGTTCCCGCGGCCAAGC

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MFTGIVEELGEVTARDVLADAARLTIRGAVVTADAGHGDSIAVNGVCLTVAELLPDGRFSADVMGETLNRSNLGALQVGS
RVNLERAAAVNSRLGGHIVQGHVDGTGRIVARTPSEHWEVVRIEVPPEVARYVVEKGSITVDGISLTVSGLGGEPRDWFE
VSLIPTTRELTTLGGAPVGTQVNLEVDVIAKYVERLMSR

Sequences:

>Translated_199_residues
MFTGIVEELGEVTARDVLADAARLTIRGAVVTADAGHGDSIAVNGVCLTVAELLPDGRFSADVMGETLNRSNLGALQVGS
RVNLERAAAVNSRLGGHIVQGHVDGTGRIVARTPSEHWEVVRIEVPPEVARYVVEKGSITVDGISLTVSGLGGEPRDWFE
VSLIPTTRELTTLGGAPVGTQVNLEVDVIAKYVERLMSR
>Mature_199_residues
MFTGIVEELGEVTARDVLADAARLTIRGAVVTADAGHGDSIAVNGVCLTVAELLPDGRFSADVMGETLNRSNLGALQVGS
RVNLERAAAVNSRLGGHIVQGHVDGTGRIVARTPSEHWEVVRIEVPPEVARYVVEKGSITVDGISLTVSGLGGEPRDWFE
VSLIPTTRELTTLGGAPVGTQVNLEVDVIAKYVERLMSR

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=210, Percent_Identity=37.6190476190476, Blast_Score=107, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6319733, Length=206, Percent_Identity=39.3203883495146, Blast_Score=128, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 21034; Mature: 21034

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVEELGEVTARDVLADAARLTIRGAVVTADAGHGDSIAVNGVCLTVAELLPDGRFS
CCCHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCEEEECHHHHHHHHHCCCCCCC
ADVMGETLNRSNLGALQVGSRVNLERAAAVNSRLGGHIVQGHVDGTGRIVARTPSEHWEV
HHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCEEE
VRIEVPPEVARYVVEKGSITVDGISLTVSGLGGEPRDWFEVSLIPTTRELTTLGGAPVGT
EEEECCHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCEEEEEEECCCHHHHHCCCCCCCC
QVNLEVDVIAKYVERLMSR
EEEEHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFTGIVEELGEVTARDVLADAARLTIRGAVVTADAGHGDSIAVNGVCLTVAELLPDGRFS
CCCHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCEEEECHHHHHHHHHCCCCCCC
ADVMGETLNRSNLGALQVGSRVNLERAAAVNSRLGGHIVQGHVDGTGRIVARTPSEHWEV
HHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCEEE
VRIEVPPEVARYVVEKGSITVDGISLTVSGLGGEPRDWFEVSLIPTTRELTTLGGAPVGT
EEEECCHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCEEEEEEECCCHHHHHCCCCCCCC
QVNLEVDVIAKYVERLMSR
EEEEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]