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The map label for this gene is rpe

Identifier: 41407233

GI number: 41407233

Start: 1189816

End: 1190514

Strand: Direct

Name: rpe

Synonym: MAP1135

Alternate gene names: 41407233

Gene position: 1189816-1190514 (Clockwise)

Preceding gene: 41407232

Following gene: 41407234

Centisome position: 24.63

GC content: 70.67

Gene sequence:

>699_bases
ATGCCTTGCAACACGGGACAGCCGCGGGGACCGCTGATCGCGCCGTCGATCCTGTCCGCCGACTTCTCCCGGCTGGCCGA
CGAAGCCGCCGCCGTGACCGGCGCCGACTGGTTGCACGTCGACGTGATGGACAACCACTTCGTGCCGAATCTCACGATCG
GGCTGCCGGTGGTCCAGAGCCTGCTGGCCACCACCACCATCCCGATGGACTGCCATCTGATGATCGAGAACCCGGACCGC
TGGGCGCCGCCCTACGCCGAGGCCGGCGCCCACAACGTCACCTTCCACGCCGAGGCCACCGACAACCCGATCGGCGTCGC
CCGCGACATCCGCGCCGCCGGCGCCAAGGCGGGGATCAGCGTGAAGCCGGGCACCCCGCTGGAGCCGTACCTGGAGATCC
TGCCGCAGTTCGACACCCTGCTGATCATGTCGGTGGAGCCCGGCTTCGGCGGCCAGAGCTTCATCCCCGAAGTCCTCGGC
AAGGTGCGCACCGCCCGCAAGCTGATCGACGCGGGGGAGCTGACCATCCTGGTCGAGATCGACGGCGGCATCAACGCCGA
CACCATCGAGCAGGCCGCCGAGGCCGGCGTCGACTGCTTCGTCGCCGGGTTGGCCGTGTACGGCGCCGACGACCCGGCCG
CAGCGGTCGAGGCGCTGCGCCGGCAGGCCCTGGGCGCGTCCCAGCACCTGCGTCGATGA

Upstream 100 bases:

>100_bases
ACAAATGGACCTGGCCGCGTCGGCCCTGCGCCGCGAAGCGGGGTAGGGCGGCGGTCTCCGGATGTGAACAGAGCGGCGGC
GCTTCAGTAGTCTGGCGCTC

Downstream 100 bases:

>100_bases
CCGCGTCGCTGGGCGACCGCCTGGACGCCGCGATGCACCTGGCGATCGAACAGTCCAATCAGGTCAAGGGCAACACCTAT
CCCAACCCGCCGGTGGGCGC

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MPCNTGQPRGPLIAPSILSADFSRLADEAAAVTGADWLHVDVMDNHFVPNLTIGLPVVQSLLATTTIPMDCHLMIENPDR
WAPPYAEAGAHNVTFHAEATDNPIGVARDIRAAGAKAGISVKPGTPLEPYLEILPQFDTLLIMSVEPGFGGQSFIPEVLG
KVRTARKLIDAGELTILVEIDGGINADTIEQAAEAGVDCFVAGLAVYGADDPAAAVEALRRQALGASQHLRR

Sequences:

>Translated_232_residues
MPCNTGQPRGPLIAPSILSADFSRLADEAAAVTGADWLHVDVMDNHFVPNLTIGLPVVQSLLATTTIPMDCHLMIENPDR
WAPPYAEAGAHNVTFHAEATDNPIGVARDIRAAGAKAGISVKPGTPLEPYLEILPQFDTLLIMSVEPGFGGQSFIPEVLG
KVRTARKLIDAGELTILVEIDGGINADTIEQAAEAGVDCFVAGLAVYGADDPAAAVEALRRQALGASQHLRR
>Mature_231_residues
PCNTGQPRGPLIAPSILSADFSRLADEAAAVTGADWLHVDVMDNHFVPNLTIGLPVVQSLLATTTIPMDCHLMIENPDRW
APPYAEAGAHNVTFHAEATDNPIGVARDIRAAGAKAGISVKPGTPLEPYLEILPQFDTLLIMSVEPGFGGQSFIPEVLGK
VRTARKLIDAGELTILVEIDGGINADTIEQAAEAGVDCFVAGLAVYGADDPAAAVEALRRQALGASQHLRR

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=223, Percent_Identity=42.152466367713, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI219879828, Length=223, Percent_Identity=40.8071748878924, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI24307923, Length=175, Percent_Identity=36, Blast_Score=120, Evalue=1e-27,
Organism=Escherichia coli, GI1789788, Length=220, Percent_Identity=45.4545454545455, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1790523, Length=193, Percent_Identity=34.7150259067358, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790754, Length=207, Percent_Identity=31.4009661835749, Blast_Score=104, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17552948, Length=218, Percent_Identity=44.4954128440367, Blast_Score=186, Evalue=9e-48,
Organism=Saccharomyces cerevisiae, GI6322341, Length=236, Percent_Identity=41.5254237288136, Blast_Score=194, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24586301, Length=211, Percent_Identity=42.654028436019, Blast_Score=174, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24447; Mature: 24316

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPCNTGQPRGPLIAPSILSADFSRLADEAAAVTGADWLHVDVMDNHFVPNLTIGLPVVQS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEECHHHHHH
LLATTTIPMDCHLMIENPDRWAPPYAEAGAHNVTFHAEATDNPIGVARDIRAAGAKAGIS
HHHHCCCCCEEEEEEECCCCCCCCHHHCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCE
VKPGTPLEPYLEILPQFDTLLIMSVEPGFGGQSFIPEVLGKVRTARKLIDAGELTILVEI
ECCCCCHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
DGGINADTIEQAAEAGVDCFVAGLAVYGADDPAAAVEALRRQALGASQHLRR
CCCCCHHHHHHHHHCCHHHHHHHHHEECCCCHHHHHHHHHHHHCCHHHHHCC
>Mature Secondary Structure 
PCNTGQPRGPLIAPSILSADFSRLADEAAAVTGADWLHVDVMDNHFVPNLTIGLPVVQS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEECHHHHHH
LLATTTIPMDCHLMIENPDRWAPPYAEAGAHNVTFHAEATDNPIGVARDIRAAGAKAGIS
HHHHCCCCCEEEEEEECCCCCCCCHHHCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCE
VKPGTPLEPYLEILPQFDTLLIMSVEPGFGGQSFIPEVLGKVRTARKLIDAGELTILVEI
ECCCCCHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
DGGINADTIEQAAEAGVDCFVAGLAVYGADDPAAAVEALRRQALGASQHLRR
CCCCCHHHHHHHHHCCHHHHHHHHHEECCCCHHHHHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]