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The map label for this gene is pyrR

Identifier: 41407212

GI number: 41407212

Start: 1166621

End: 1167193

Strand: Direct

Name: pyrR

Synonym: MAP1114

Alternate gene names: 41407212

Gene position: 1166621-1167193 (Clockwise)

Preceding gene: 41407209

Following gene: 41407213

Centisome position: 24.15

GC content: 71.2

Gene sequence:

>573_bases
ATGGGTGCTGCGGGCAACACCGGCTCGTCCGGTGATTCCCGGGAGTTGATGTCGGCGGCCGACGTCGGCCGCACCATTTC
CCGCATCGCGCATCAGATCATCGAAAAGACCGCGCTGGACGGTCCGGACGGGCCGCGGGTGGTGCTGCTGGGCATCCCGA
CCCGCGGCGTCACCCTGGCCGACCGGCTGGCCCGCAACATCGGCGAGTACAGCGGGGTCGAGGTCGGCCACGGCGCCCTG
GACATCACCCTGTATCGCGACGACCTGATGCAAAAACCGCCGCGGCCGCTGGAGGCCACCTCGATCCCGGCCGGCGGCAT
CGACGACGCGCTGGTGATCCTGGTCGACGACGTGCTCTACTCCGGCCGCTCGGTGCGCTCGGCACTGGACGCGCTGCGCG
ACGTGGGCCGCCCGCGGGTGGTGCAACTGGCGGTGCTGGTCGACCGCGGTCACCGCGAGCTGCCGCTGCGCGCCGACTAC
GTCGGCAAGAACGTCCCCACCTCGCGCAGTGAGAGCGTGCACGTGCTGCTGGCCGAGCACGACGGCGCCGACGGGGTGGT
GATCTCGCGATGA

Upstream 100 bases:

>100_bases
CGCCGCGCGCGGTCGCCCGCGAAATTAGTGCTACGCTGCCGTGCAGTCGACATCCTTTAACGATCCGTCCGGTGAGGCGG
AGAAGGAGGTCAAGTTTCGC

Downstream 100 bases:

>100_bases
CCCGCCACCTGCTCGCCGCCGGCGACCTGAGCCGCGACGACGCCACCGCCATCCTCGACGACGCCGACCGGTTCGCCCAG
GCGCTGGTGGGCCGCGAGAT

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MGAAGNTGSSGDSRELMSAADVGRTISRIAHQIIEKTALDGPDGPRVVLLGIPTRGVTLADRLARNIGEYSGVEVGHGAL
DITLYRDDLMQKPPRPLEATSIPAGGIDDALVILVDDVLYSGRSVRSALDALRDVGRPRVVQLAVLVDRGHRELPLRADY
VGKNVPTSRSESVHVLLAEHDGADGVVISR

Sequences:

>Translated_190_residues
MGAAGNTGSSGDSRELMSAADVGRTISRIAHQIIEKTALDGPDGPRVVLLGIPTRGVTLADRLARNIGEYSGVEVGHGAL
DITLYRDDLMQKPPRPLEATSIPAGGIDDALVILVDDVLYSGRSVRSALDALRDVGRPRVVQLAVLVDRGHRELPLRADY
VGKNVPTSRSESVHVLLAEHDGADGVVISR
>Mature_189_residues
GAAGNTGSSGDSRELMSAADVGRTISRIAHQIIEKTALDGPDGPRVVLLGIPTRGVTLADRLARNIGEYSGVEVGHGALD
ITLYRDDLMQKPPRPLEATSIPAGGIDDALVILVDDVLYSGRSVRSALDALRDVGRPRVVQLAVLVDRGHRELPLRADYV
GKNVPTSRSESVHVLLAEHDGADGVVISR

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 20113; Mature: 19982

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAAGNTGSSGDSRELMSAADVGRTISRIAHQIIEKTALDGPDGPRVVLLGIPTRGVTLA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHH
DRLARNIGEYSGVEVGHGALDITLYRDDLMQKPPRPLEATSIPAGGIDDALVILVDDVLY
HHHHHHHHHHCCCEECCCEEEEEEECHHHHCCCCCCCCCCCCCCCCCCCCHHEEEHHHHH
SGRSVRSALDALRDVGRPRVVQLAVLVDRGHRELPLRADYVGKNVPTSRSESVHVLLAEH
CCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCHHHCCCCCCCCCCCCEEEEEEEC
DGADGVVISR
CCCCCEEEEC
>Mature Secondary Structure 
GAAGNTGSSGDSRELMSAADVGRTISRIAHQIIEKTALDGPDGPRVVLLGIPTRGVTLA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHH
DRLARNIGEYSGVEVGHGALDITLYRDDLMQKPPRPLEATSIPAGGIDDALVILVDDVLY
HHHHHHHHHHCCCEECCCEEEEEEECHHHHCCCCCCCCCCCCCCCCCCCCHHEEEHHHHH
SGRSVRSALDALRDVGRPRVVQLAVLVDRGHRELPLRADYVGKNVPTSRSESVHVLLAEH
CCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCHHHCCCCCCCCCCCCEEEEEEEC
DGADGVVISR
CCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA