Click here to switch to the map view.

The map label for this gene is purQ

Identifier: 41406724

GI number: 41406724

Start: 650821

End: 651495

Strand: Direct

Name: purQ

Synonym: MAP0626

Alternate gene names: 41406724

Gene position: 650821-651495 (Clockwise)

Preceding gene: 41406723

Following gene: 41406730

Centisome position: 13.48

GC content: 70.52

Gene sequence:

>675_bases
GTGACTGCACGCATCGGGATCATCACCTTCCCCGGGACGCTCGACGACGTGGACGCCGCGCGGGCGGCGCGACGGGTCGG
CGCGCAGCCGGTCAGCCTGTGGCACGCCGACGCCGACCTCAAGGGTGTCGACGCGGTGGTGGTGCCCGGCGGCTTCTCCT
ACGGCGACTACCTGCGGGCCGGGGCGATCGCCCGGTTCGCCCCGGTGATGACCGAAGTCGTCGACGCCGCCCGCCGCGGA
ATGCCAGTGTTGGGTATTTGCAACGGTTTTCAGGTGCTCTGCGAGGCCGGGCTGCTGCCCGGCGCGTTGACCCGCAACGT
GGGTCTGCACTTCATCTGCCGCGACGTGTGGCTGCGGGTGGCCTCGACGTCGACGGCGTGGACGTCGAGGTTCGAACCCG
ACGCCGATCTGCTGGTGCCGCTGAAATCCGGTGAGGGCCGCTACGTCGCCCCCGCCGACGTGCTCGACGAACTCGAGGGC
GAGGGACGGGTGGTGTTCCGCTACCACGAGAACCTCAACGGGTCCCAGCGCGACATCGCCGGCGTCAGCTCCGCCGACGG
CCGCGTGGTGGGGCTGATGCCGCATCCCGAACATGCCATCGAGGCGCTGACCGGGCCTTCCGACGACGGCCTGGGCCTGT
TCTATTCGGTGCTGGACGGCGTGCTCGCCGGCTGA

Upstream 100 bases:

>100_bases
AGGTCGATGACAGCGTCGACGATGCGGCGCTCGCCGAGATCGCCGAAACGCTGTTGGCCAACACCGTGATCGAGGACTGG
ACGATCAGCCGGGAGACGCA

Downstream 100 bases:

>100_bases
GCGCCGGGACGTCAGCCCGCGTCGCGCAGCAACGGTACGTGCGCCGGCGGTGCGGCGGGGTTCAACTCCTCGAAGAGTTG
GGTCGCGTCCGCGATCGTCT

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MTARIGIITFPGTLDDVDAARAARRVGAQPVSLWHADADLKGVDAVVVPGGFSYGDYLRAGAIARFAPVMTEVVDAARRG
MPVLGICNGFQVLCEAGLLPGALTRNVGLHFICRDVWLRVASTSTAWTSRFEPDADLLVPLKSGEGRYVAPADVLDELEG
EGRVVFRYHENLNGSQRDIAGVSSADGRVVGLMPHPEHAIEALTGPSDDGLGLFYSVLDGVLAG

Sequences:

>Translated_224_residues
MTARIGIITFPGTLDDVDAARAARRVGAQPVSLWHADADLKGVDAVVVPGGFSYGDYLRAGAIARFAPVMTEVVDAARRG
MPVLGICNGFQVLCEAGLLPGALTRNVGLHFICRDVWLRVASTSTAWTSRFEPDADLLVPLKSGEGRYVAPADVLDELEG
EGRVVFRYHENLNGSQRDIAGVSSADGRVVGLMPHPEHAIEALTGPSDDGLGLFYSVLDGVLAG
>Mature_223_residues
TARIGIITFPGTLDDVDAARAARRVGAQPVSLWHADADLKGVDAVVVPGGFSYGDYLRAGAIARFAPVMTEVVDAARRGM
PVLGICNGFQVLCEAGLLPGALTRNVGLHFICRDVWLRVASTSTAWTSRFEPDADLLVPLKSGEGRYVAPADVLDELEGE
GRVVFRYHENLNGSQRDIAGVSSADGRVVGLMPHPEHAIEALTGPSDDGLGLFYSVLDGVLAG

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=231, Percent_Identity=28.1385281385281, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR010075 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 23684; Mature: 23553

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARIGIITFPGTLDDVDAARAARRVGAQPVSLWHADADLKGVDAVVVPGGFSYGDYLRA
CCEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCCHHHHHHH
GAIARFAPVMTEVVDAARRGMPVLGICNGFQVLCEAGLLPGALTRNVGLHFICRDVWLRV
HHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHH
ASTSTAWTSRFEPDADLLVPLKSGEGRYVAPADVLDELEGEGRVVFRYHENLNGSQRDIA
HCCCCHHHCCCCCCCCEEEEEECCCCCEECHHHHHHHCCCCCEEEEEEECCCCCCCHHHC
GVSSADGRVVGLMPHPEHAIEALTGPSDDGLGLFYSVLDGVLAG
CCCCCCCEEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TARIGIITFPGTLDDVDAARAARRVGAQPVSLWHADADLKGVDAVVVPGGFSYGDYLRA
CEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCCHHHHHHH
GAIARFAPVMTEVVDAARRGMPVLGICNGFQVLCEAGLLPGALTRNVGLHFICRDVWLRV
HHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHH
ASTSTAWTSRFEPDADLLVPLKSGEGRYVAPADVLDELEGEGRVVFRYHENLNGSQRDIA
HCCCCHHHCCCCCCCCEEEEEECCCCCEECHHHHHHHCCCCCEEEEEEECCCCCCCHHHC
GVSSADGRVVGLMPHPEHAIEALTGPSDDGLGLFYSVLDGVLAG
CCCCCCCEEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]