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The map label for this gene is fabG

Identifier: 41406659

GI number: 41406659

Start: 585296

End: 586210

Strand: Direct

Name: fabG

Synonym: MAP0561

Alternate gene names: 41406659

Gene position: 585296-586210 (Clockwise)

Preceding gene: 41406658

Following gene: 41406660

Centisome position: 12.12

GC content: 69.95

Gene sequence:

>915_bases
TTGACTAGCAGCACGAACGCGACCGATCTGTCCGGAAAGGTCGCGGTGGTGACCGGTGCGGCCGCGGGCCTGGGACGCGC
CGAGGCGCTCGGGCTGGCACGCCTGGGCGCGACCGTCGTCGTCAACGACATCGCCACCGCGCTGGACGCCTCCGACGTCA
TCGACGAGATCAACGCCGCCGGCTCCAAGGCCGTCGCGGTGGCCGGCGACATCAGCGAACGCGCCACCGCCGACGAATTG
GTTGCTCAGGCCGACGGGCTGGGCGGGCTGGACATCGTGGTGAACAACGCCGGCATCACCCGCGACCGGATGCTGTTCAA
CATGTCCGACGAGGAGTGGGACCTGGTCATCGCCGTGCACCTGCGCGGCCACTTCCTGCTGACCCGCAACGCCGCCGCCT
ACTGGCGCTCGAGGGCCAAGGAGGCCGGCGGCCGGATCTTCGGCCGCATCGTCAACACCGCGTCGGAGGCCGGCCTGGTC
GGCCCGGTCGGGCAGGCGAACTACGGCGCCGCCAAGGCCGGCATCATCTCGCTGACCCTGACGGCCGCCCGCGCGCTGGG
CCGCTACGGCGTGTGCGCCAACGCGATCTGCCCCCGGGCGCGCACCGCGATGACGGCCGACGTGTTCGGCGATGCGCCCG
AGGTCCCGGCCGGCGGGGTCGACCCGCTGTCGCCCGAGCATGTGGTCAACCTGGTCACGTTCCTGTCGTCGCCGGCCGCC
GCCGAAGTGAACGGGCAGGTGTTCATCGTCTACGGTCCACAGGTGACACTTGTCGCTGCGCCGACCGCCGAGCACAAATT
CAGCGCGCAAGGCCCCGCGTGGGACCCCGCCGAACTCAGCGCGACGTTGCAGGATTACTTTGCTGGACGTGATCCCGAGC
ACAATTTTTCGGCGAGCGCACTGATGGAGCAATAG

Upstream 100 bases:

>100_bases
GGAGCAGTTGGCCGAGCAGGCGATCGCCGAATGCCCGCGCGCGGCGCTGTCGCGCGGCGACTGAACCGGGCGGAACACAG
AAACTAGAGGTATTCATAAA

Downstream 100 bases:

>100_bases
CTGGGGGCAGCTAATCGGCGGGGGGAAATCAGCAGGTAGAACGTGTGTCAGTTTGACACGTGACAAGTGCGTCTGACCTG
CTGAATTAACGGTTGGGATA

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MTSSTNATDLSGKVAVVTGAAAGLGRAEALGLARLGATVVVNDIATALDASDVIDEINAAGSKAVAVAGDISERATADEL
VAQADGLGGLDIVVNNAGITRDRMLFNMSDEEWDLVIAVHLRGHFLLTRNAAAYWRSRAKEAGGRIFGRIVNTASEAGLV
GPVGQANYGAAKAGIISLTLTAARALGRYGVCANAICPRARTAMTADVFGDAPEVPAGGVDPLSPEHVVNLVTFLSSPAA
AEVNGQVFIVYGPQVTLVAAPTAEHKFSAQGPAWDPAELSATLQDYFAGRDPEHNFSASALMEQ

Sequences:

>Translated_304_residues
MTSSTNATDLSGKVAVVTGAAAGLGRAEALGLARLGATVVVNDIATALDASDVIDEINAAGSKAVAVAGDISERATADEL
VAQADGLGGLDIVVNNAGITRDRMLFNMSDEEWDLVIAVHLRGHFLLTRNAAAYWRSRAKEAGGRIFGRIVNTASEAGLV
GPVGQANYGAAKAGIISLTLTAARALGRYGVCANAICPRARTAMTADVFGDAPEVPAGGVDPLSPEHVVNLVTFLSSPAA
AEVNGQVFIVYGPQVTLVAAPTAEHKFSAQGPAWDPAELSATLQDYFAGRDPEHNFSASALMEQ
>Mature_303_residues
TSSTNATDLSGKVAVVTGAAAGLGRAEALGLARLGATVVVNDIATALDASDVIDEINAAGSKAVAVAGDISERATADELV
AQADGLGGLDIVVNNAGITRDRMLFNMSDEEWDLVIAVHLRGHFLLTRNAAAYWRSRAKEAGGRIFGRIVNTASEAGLVG
PVGQANYGAAKAGIISLTLTAARALGRYGVCANAICPRARTAMTADVFGDAPEVPAGGVDPLSPEHVVNLVTFLSSPAAA
EVNGQVFIVYGPQVTLVAAPTAEHKFSAQGPAWDPAELSATLQDYFAGRDPEHNFSASALMEQ

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4504505, Length=250, Percent_Identity=41.2, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI15277342, Length=263, Percent_Identity=38.4030418250951, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI4758504, Length=196, Percent_Identity=33.6734693877551, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=30.0395256916996, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI83715985, Length=189, Percent_Identity=33.8624338624339, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI31542939, Length=194, Percent_Identity=34.020618556701, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI209862901, Length=202, Percent_Identity=32.6732673267327, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI19923983, Length=202, Percent_Identity=32.6732673267327, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=30.0813008130081, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=35.0597609561753, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1789208, Length=264, Percent_Identity=29.5454545454545, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=29.3650793650794, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=29.5719844357977, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082160, Length=256, Percent_Identity=27.34375, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786812, Length=265, Percent_Identity=30.188679245283, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=31.3253012048193, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787905, Length=255, Percent_Identity=32.156862745098, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789057, Length=265, Percent_Identity=29.4339622641509, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI2367175, Length=191, Percent_Identity=33.5078534031414, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789378, Length=194, Percent_Identity=30.4123711340206, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17568967, Length=248, Percent_Identity=38.7096774193548, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17555706, Length=256, Percent_Identity=32.8125, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17564282, Length=193, Percent_Identity=31.0880829015544, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI193203117, Length=230, Percent_Identity=30.4347826086957, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193203115, Length=231, Percent_Identity=30.3030303030303, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=194, Percent_Identity=34.020618556701, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=253, Percent_Identity=30.0395256916996, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=26.9230769230769, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=224, Percent_Identity=29.0178571428571, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=221, Percent_Identity=32.1266968325792, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17555612, Length=271, Percent_Identity=29.8892988929889, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71997099, Length=207, Percent_Identity=31.4009661835749, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=218, Percent_Identity=32.1100917431193, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=282, Percent_Identity=26.5957446808511, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=255, Percent_Identity=28.2352941176471, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=139, Percent_Identity=32.3741007194245, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=248, Percent_Identity=38.7096774193548, Blast_Score=149, Evalue=6e-37,
Organism=Drosophila melanogaster, GI18859837, Length=253, Percent_Identity=39.5256916996047, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=37.6984126984127, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17737361, Length=192, Percent_Identity=35.9375, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI23397609, Length=191, Percent_Identity=34.0314136125654, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24644339, Length=210, Percent_Identity=29.0476190476191, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24649181, Length=167, Percent_Identity=32.3353293413174, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 31197; Mature: 31066

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSTNATDLSGKVAVVTGAAAGLGRAEALGLARLGATVVVNDIATALDASDVIDEINAA
CCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEEHHHHHHHCHHHHHHHHHCC
GSKAVAVAGDISERATADELVAQADGLGGLDIVVNNAGITRDRMLFNMSDEEWDLVIAVH
CCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHEEEECCCCCEEEEEEEE
LRGHFLLTRNAAAYWRSRAKEAGGRIFGRIVNTASEAGLVGPVGQANYGAAKAGIISLTL
ECCEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCEEEEHH
TAARALGRYGVCANAICPRARTAMTADVFGDAPEVPAGGVDPLSPEHVVNLVTFLSSPAA
HHHHHHHCCCCHHHHCCCCHHHHEEHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
AEVNGQVFIVYGPQVTLVAAPTAEHKFSAQGPAWDPAELSATLQDYFAGRDPEHNFSASA
EECCCEEEEEECCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHH
LMEQ
HHCC
>Mature Secondary Structure 
TSSTNATDLSGKVAVVTGAAAGLGRAEALGLARLGATVVVNDIATALDASDVIDEINAA
CCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEEHHHHHHHCHHHHHHHHHCC
GSKAVAVAGDISERATADELVAQADGLGGLDIVVNNAGITRDRMLFNMSDEEWDLVIAVH
CCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHEEEECCCCCEEEEEEEE
LRGHFLLTRNAAAYWRSRAKEAGGRIFGRIVNTASEAGLVGPVGQANYGAAKAGIISLTL
ECCEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCEEEEHH
TAARALGRYGVCANAICPRARTAMTADVFGDAPEVPAGGVDPLSPEHVVNLVTFLSSPAA
HHHHHHHCCCCHHHHCCCCHHHHEEHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
AEVNGQVFIVYGPQVTLVAAPTAEHKFSAQGPAWDPAELSATLQDYFAGRDPEHNFSASA
EECCCEEEEEECCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHH
LMEQ
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]