| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
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The map label for this gene is fabG [H]
Identifier: 41406615
GI number: 41406615
Start: 543945
End: 544742
Strand: Direct
Name: fabG [H]
Synonym: MAP0517
Alternate gene names: 41406615
Gene position: 543945-544742 (Clockwise)
Preceding gene: 41406608
Following gene: 41406616
Centisome position: 11.26
GC content: 68.17
Gene sequence:
>798_bases GTGACTCGCGCCGAAGCATGCCCCCCGTTTGCAGAAGCCATCAACCTGGGGCTGACCGGTCGGGTGGTCCTGGTCACCGG CGGAGTTCGCGGGGTCGGTGCCGGCATCAGCTCGGTTTTCGCCGCACAGGGCGCCACCGTCGTCACCTGCGCGCGGCGGG CGGTCGAGGGGCTGCCGTATGAGTTCCACTCCTGCGATGTCCGCGACGACGACGCCGTCAAGGCGCTGATCGATACCATC GCCGACCGGCACGGCAGGCTCGACGTCGTGGTCAACAACGCCGGGGGATCGCCCTACGTGCTGACCGCAGAATCCAGCGC CAAGTTCAACCGCAAGATCATCGAACTGAACCTCATTGGCGCGCTGTCGGTTTCGCAGCACGCCAACGCTCACATGCAGA AGCAGGCCCAGGGCGGGTCGATCGTCAACATCTGCAGCCTGTCCGGCCGCCGGCCCTCGCCGGGCACCGGCGCCTACGGG GCGGCCAAGGCCGGCCTGGAAAGCCTCACCCAGACCCTGGCGGTGGAGTGGGGGCCCAAGGTCCGGGTGAACGCCTGCGT GGTGGGCATGGTGGAGACCGAGCAGTCGGAGCTGTTCTACGGCGACGCCGACTCCATCGCCGCGATCTCGAAGAACGTGC CCCTGGGCCGGTTGGCCAAGCCGGCCGACATCGGTTGGGCCGCAGCATTTTTAGCCTCCGATGCGGCCTGCTACATCAGC GGGGCCTCGCTGGAGGTGCACGGCGGCGGTGAGCCGCCGCACTATCTGGCCACCACGAACGCGAGCGCGATCAAGTAG
Upstream 100 bases:
>100_bases GCGACGATGCCCGGTTCGATGGTTTTGGATGTGATGGGCAAGGTGCCACTTCCTTGTGGGGTAACTACCTAAGCAAGCAC TTGCTTGGTACGCTAGCACA
Downstream 100 bases:
>100_bases AGGAGACAAGGACTATGGGAGTGGTTGACGGCCGCGTCGTCATCGTCACCGGAGCGGGCGGCGGTATCGGTCGCGCGCAC GCACTGGCCTTCGCCGCCGA
Product: short chain dehydrogenase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 265; Mature: 264
Protein sequence:
>265_residues MTRAEACPPFAEAINLGLTGRVVLVTGGVRGVGAGISSVFAAQGATVVTCARRAVEGLPYEFHSCDVRDDDAVKALIDTI ADRHGRLDVVVNNAGGSPYVLTAESSAKFNRKIIELNLIGALSVSQHANAHMQKQAQGGSIVNICSLSGRRPSPGTGAYG AAKAGLESLTQTLAVEWGPKVRVNACVVGMVETEQSELFYGDADSIAAISKNVPLGRLAKPADIGWAAAFLASDAACYIS GASLEVHGGGEPPHYLATTNASAIK
Sequences:
>Translated_265_residues MTRAEACPPFAEAINLGLTGRVVLVTGGVRGVGAGISSVFAAQGATVVTCARRAVEGLPYEFHSCDVRDDDAVKALIDTI ADRHGRLDVVVNNAGGSPYVLTAESSAKFNRKIIELNLIGALSVSQHANAHMQKQAQGGSIVNICSLSGRRPSPGTGAYG AAKAGLESLTQTLAVEWGPKVRVNACVVGMVETEQSELFYGDADSIAAISKNVPLGRLAKPADIGWAAAFLASDAACYIS GASLEVHGGGEPPHYLATTNASAIK >Mature_264_residues TRAEACPPFAEAINLGLTGRVVLVTGGVRGVGAGISSVFAAQGATVVTCARRAVEGLPYEFHSCDVRDDDAVKALIDTIA DRHGRLDVVVNNAGGSPYVLTAESSAKFNRKIIELNLIGALSVSQHANAHMQKQAQGGSIVNICSLSGRRPSPGTGAYGA AKAGLESLTQTLAVEWGPKVRVNACVVGMVETEQSELFYGDADSIAAISKNVPLGRLAKPADIGWAAAFLASDAACYISG ASLEVHGGGEPPHYLATTNASAIK
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=29.8387096774194, Blast_Score=109, Evalue=2e-24, Organism=Homo sapiens, GI59889578, Length=225, Percent_Identity=38.2222222222222, Blast_Score=108, Evalue=4e-24, Organism=Homo sapiens, GI19923817, Length=251, Percent_Identity=28.6852589641434, Blast_Score=99, Evalue=5e-21, Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=31.4741035856574, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI15277342, Length=252, Percent_Identity=32.5396825396825, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI40254992, Length=239, Percent_Identity=30.1255230125523, Blast_Score=92, Evalue=7e-19, Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=30.241935483871, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=26.6932270916335, Blast_Score=88, Evalue=6e-18, Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=30.6122448979592, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI4503301, Length=192, Percent_Identity=29.1666666666667, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI31542939, Length=196, Percent_Identity=29.5918367346939, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI109715829, Length=237, Percent_Identity=27.8481012658228, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI224922801, Length=181, Percent_Identity=28.7292817679558, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI126723191, Length=180, Percent_Identity=28.8888888888889, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI7706318, Length=175, Percent_Identity=30.2857142857143, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=29.8969072164948, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI4504505, Length=183, Percent_Identity=34.4262295081967, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI20149619, Length=197, Percent_Identity=27.9187817258883, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI87082100, Length=262, Percent_Identity=33.587786259542, Blast_Score=117, Evalue=6e-28, Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=31.0483870967742, Blast_Score=107, Evalue=9e-25, Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=33.3333333333333, Blast_Score=107, Evalue=9e-25, Organism=Escherichia coli, GI1788459, Length=242, Percent_Identity=30.9917355371901, Blast_Score=91, Evalue=1e-19, Organism=Escherichia coli, GI1787905, Length=251, Percent_Identity=31.0756972111554, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1786812, Length=244, Percent_Identity=29.5081967213115, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=27.6422764227642, Blast_Score=85, Evalue=4e-18, Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=27.710843373494, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=27.2357723577236, Blast_Score=80, Evalue=9e-17, Organism=Escherichia coli, GI2367365, Length=237, Percent_Identity=27.4261603375527, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI1789378, Length=257, Percent_Identity=26.0700389105058, Blast_Score=67, Evalue=8e-13, Organism=Escherichia coli, GI1787526, Length=253, Percent_Identity=25.6916996047431, Blast_Score=65, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17560676, Length=246, Percent_Identity=29.2682926829268, Blast_Score=113, Evalue=8e-26, Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=32.3770491803279, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17561272, Length=255, Percent_Identity=33.3333333333333, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17536025, Length=250, Percent_Identity=30.4, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=28.9156626506024, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=30.2788844621514, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=30.5970149253731, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17555706, Length=242, Percent_Identity=30.9917355371901, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17562910, Length=279, Percent_Identity=26.8817204301075, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=27.7566539923954, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=28.735632183908, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=30.0380228136882, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=29.1187739463602, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=30, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=27.8688524590164, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=28.7313432835821, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=27.7566539923954, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=28.7878787878788, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=27.8625954198473, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17538480, Length=271, Percent_Identity=26.5682656826568, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=25.4032258064516, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=26.5151515151515, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=26.0377358490566, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17508651, Length=198, Percent_Identity=32.3232323232323, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI71994604, Length=189, Percent_Identity=26.984126984127, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17538182, Length=198, Percent_Identity=29.7979797979798, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=25.0936329588015, Blast_Score=65, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=188, Percent_Identity=29.2553191489362, Blast_Score=78, Evalue=2e-15, Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=30.7291666666667, Blast_Score=63, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6322227, Length=195, Percent_Identity=25.6410256410256, Blast_Score=62, Evalue=7e-11, Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=31.3492063492063, Blast_Score=104, Evalue=7e-23, Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=30.8, Blast_Score=97, Evalue=9e-21, Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=29.2682926829268, Blast_Score=95, Evalue=5e-20, Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=31.0756972111554, Blast_Score=94, Evalue=8e-20, Organism=Drosophila melanogaster, GI24639444, Length=245, Percent_Identity=29.3877551020408, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI24643142, Length=242, Percent_Identity=29.3388429752066, Blast_Score=88, Evalue=6e-18, Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=30.5555555555556, Blast_Score=88, Evalue=7e-18, Organism=Drosophila melanogaster, GI24644337, Length=255, Percent_Identity=30.5882352941176, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI116007236, Length=201, Percent_Identity=29.8507462686567, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI116007234, Length=254, Percent_Identity=27.1653543307087, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI116007238, Length=224, Percent_Identity=25.8928571428571, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24580925, Length=178, Percent_Identity=29.2134831460674, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI116007232, Length=187, Percent_Identity=29.9465240641711, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24641232, Length=196, Percent_Identity=26.530612244898, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI21358495, Length=202, Percent_Identity=23.7623762376238, Blast_Score=64, Evalue=1e-10,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 27273; Mature: 27142
Theoretical pI: Translated: 6.77; Mature: 6.77
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.3 %Cys (Translated Protein) 1.1 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 2.3 %Cys (Mature Protein) 0.8 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTRAEACPPFAEAINLGLTGRVVLVTGGVRGVGAGISSVFAAQGATVVTCARRAVEGLPY CCCCCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCE EFHSCDVRDDDAVKALIDTIADRHGRLDVVVNNAGGSPYVLTAESSAKFNRKIIELNLIG EEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCCCCCCEEEEEEEEEE ALSVSQHANAHMQKQAQGGSIVNICSLSGRRPSPGTGAYGAAKAGLESLTQTLAVEWGPK EEECCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC VRVNACVVGMVETEQSELFYGDADSIAAISKNVPLGRLAKPADIGWAAAFLASDAACYIS EEEEEEEEEEEECCCCEEEECCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCEEEEE GASLEVHGGGEPPHYLATTNASAIK CCEEEECCCCCCCCEEEECCCCCCC >Mature Secondary Structure TRAEACPPFAEAINLGLTGRVVLVTGGVRGVGAGISSVFAAQGATVVTCARRAVEGLPY CCCCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCE EFHSCDVRDDDAVKALIDTIADRHGRLDVVVNNAGGSPYVLTAESSAKFNRKIIELNLIG EEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCCCCCCEEEEEEEEEE ALSVSQHANAHMQKQAQGGSIVNICSLSGRRPSPGTGAYGAAKAGLESLTQTLAVEWGPK EEECCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC VRVNACVVGMVETEQSELFYGDADSIAAISKNVPLGRLAKPADIGWAAAFLASDAACYIS EEEEEEEEEEEECCCCEEEECCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCEEEEE GASLEVHGGGEPPHYLATTNASAIK CCEEEECCCCCCCCEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]