| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
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The map label for this gene is fabG [H]
Identifier: 41406606
GI number: 41406606
Start: 536184
End: 536972
Strand: Direct
Name: fabG [H]
Synonym: MAP0508
Alternate gene names: 41406606
Gene position: 536184-536972 (Clockwise)
Preceding gene: 41406605
Following gene: 41406607
Centisome position: 11.1
GC content: 69.71
Gene sequence:
>789_bases ATGAGCCTGTCCGAAGCTCCGAAAGAGATTGCGGGACACGGGCTTCTGGAAGGCAAGGTGGTGATCGTCACCGCGGCGGC CGGCACGGGTATCGGCTCGGCGACGGCCAAACGAGCGCTCGCCGAGGGCGCCGACGTGGTGATCTCCGACCACCACGAGC GACGGCTGGGCGAGACCGCCGACCAGCTCGCCGCGCTCGGCCAGGGCCGGGTGGAAAGCGTGCTGTGCGACGTGACGTCC ACCGCCCAGGTCGATGCGCTGTTCGCGTCGGCCCACGCCCGGATGGGGCGCATCGACGTGCTGGTCAACAACGCCGGGCT GGGCGGGCAGACCCCGGTGGTCGACATGACCGACGACGAGTGGGACCGGGTGCTCGATGTCACCCTGACCTCGGTTTTCC GCGCCACCCGTGCCGCGCTGCGCTACTTCCGCGACGCGCCGCACGGCGGGGTGATCGTCAACAACGCCAGCGTGCTGGGC TGGCGGGCGCAGCACTCACAGTCGCACTACGCCGCCGCCAAGGCCGGGGTGATGGCGTTGACCCGGTGCAGCGCAATCGA AGCCGCCGAGTACGACGTGCGGATCAACGCGGTGTCGCCGAGCATCGCCCGGCACAAGTTCCTGGAGAAGACGTCGTCGG CCGACCTGCTCGACCGGCTCTCGGCCGGTGAGGCGTTCGGTCGCGCCGCCGAGCCCTGGGAGGTCGCGGCCACCATCGCG TTTTTGGCCAGCGACTACTCCAGCTACCTGACCGGCGAGGTCATCTCGGTGTCCAGCCAGCATCCATGA
Upstream 100 bases:
>100_bases TCCTGTTCACCCGCGCCGACACCATCTACGGCGGCTCCAACGAGATCCAGCGCAACATCATCGCCGAGCGGGTGCTCGGC CTGCCCCGGGAGGTAAAGGG
Downstream 100 bases:
>100_bases GCCGGCGTGGTCGGCCGGGACCGGCGCCCCTCCCGCTGGCCAAGCAAGCGCTTGGTTGATACTCTGTCCGGGTGGACCGA GTGACCGGTCCGGCCAACAG
Product: short chain dehydrogenase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 262; Mature: 261
Protein sequence:
>262_residues MSLSEAPKEIAGHGLLEGKVVIVTAAAGTGIGSATAKRALAEGADVVISDHHERRLGETADQLAALGQGRVESVLCDVTS TAQVDALFASAHARMGRIDVLVNNAGLGGQTPVVDMTDDEWDRVLDVTLTSVFRATRAALRYFRDAPHGGVIVNNASVLG WRAQHSQSHYAAAKAGVMALTRCSAIEAAEYDVRINAVSPSIARHKFLEKTSSADLLDRLSAGEAFGRAAEPWEVAATIA FLASDYSSYLTGEVISVSSQHP
Sequences:
>Translated_262_residues MSLSEAPKEIAGHGLLEGKVVIVTAAAGTGIGSATAKRALAEGADVVISDHHERRLGETADQLAALGQGRVESVLCDVTS TAQVDALFASAHARMGRIDVLVNNAGLGGQTPVVDMTDDEWDRVLDVTLTSVFRATRAALRYFRDAPHGGVIVNNASVLG WRAQHSQSHYAAAKAGVMALTRCSAIEAAEYDVRINAVSPSIARHKFLEKTSSADLLDRLSAGEAFGRAAEPWEVAATIA FLASDYSSYLTGEVISVSSQHP >Mature_261_residues SLSEAPKEIAGHGLLEGKVVIVTAAAGTGIGSATAKRALAEGADVVISDHHERRLGETADQLAALGQGRVESVLCDVTST AQVDALFASAHARMGRIDVLVNNAGLGGQTPVVDMTDDEWDRVLDVTLTSVFRATRAALRYFRDAPHGGVIVNNASVLGW RAQHSQSHYAAAKAGVMALTRCSAIEAAEYDVRINAVSPSIARHKFLEKTSSADLLDRLSAGEAFGRAAEPWEVAATIAF LASDYSSYLTGEVISVSSQHP
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=33.2046332046332, Blast_Score=113, Evalue=2e-25, Organism=Homo sapiens, GI15277342, Length=239, Percent_Identity=30.9623430962343, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI10190704, Length=245, Percent_Identity=32.2448979591837, Blast_Score=102, Evalue=4e-22, Organism=Homo sapiens, GI32483357, Length=259, Percent_Identity=30.1158301158301, Blast_Score=102, Evalue=4e-22, Organism=Homo sapiens, GI31542939, Length=203, Percent_Identity=32.0197044334975, Blast_Score=89, Evalue=6e-18, Organism=Homo sapiens, GI5031737, Length=250, Percent_Identity=28.4, Blast_Score=88, Evalue=1e-17, Organism=Homo sapiens, GI7705925, Length=250, Percent_Identity=30.8, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI4758504, Length=252, Percent_Identity=30.1587301587302, Blast_Score=84, Evalue=9e-17, Organism=Homo sapiens, GI40254992, Length=183, Percent_Identity=31.1475409836066, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI59889578, Length=217, Percent_Identity=31.3364055299539, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI126723750, Length=259, Percent_Identity=28.957528957529, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI4504505, Length=211, Percent_Identity=29.3838862559242, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI66933014, Length=254, Percent_Identity=29.9212598425197, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI224922801, Length=177, Percent_Identity=32.2033898305085, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI33667109, Length=199, Percent_Identity=29.1457286432161, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI83715985, Length=177, Percent_Identity=33.8983050847458, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4503301, Length=219, Percent_Identity=25.5707762557078, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI40254986, Length=221, Percent_Identity=28.9592760180996, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI126723191, Length=193, Percent_Identity=29.5336787564767, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI20149619, Length=196, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=34.412955465587, Blast_Score=132, Evalue=2e-32, Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=35.2226720647773, Blast_Score=129, Evalue=2e-31, Organism=Escherichia coli, GI87082100, Length=261, Percent_Identity=36.0153256704981, Blast_Score=117, Evalue=6e-28, Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=29.2181069958848, Blast_Score=98, Evalue=4e-22, Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=28.7449392712551, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1788459, Length=240, Percent_Identity=30, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI87082160, Length=251, Percent_Identity=25.8964143426295, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI2367175, Length=235, Percent_Identity=29.3617021276596, Blast_Score=84, Evalue=7e-18, Organism=Escherichia coli, GI1789378, Length=257, Percent_Identity=27.2373540856031, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=30.2788844621514, Blast_Score=75, Evalue=6e-15, Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=27.0491803278689, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1789057, Length=251, Percent_Identity=26.6932270916335, Blast_Score=65, Evalue=5e-12, Organism=Escherichia coli, GI1787820, Length=184, Percent_Identity=27.7173913043478, Blast_Score=62, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=31.7829457364341, Blast_Score=121, Evalue=4e-28, Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=34.412955465587, Blast_Score=121, Evalue=4e-28, Organism=Caenorhabditis elegans, GI17555706, Length=244, Percent_Identity=32.3770491803279, Blast_Score=113, Evalue=1e-25, Organism=Caenorhabditis elegans, GI17560150, Length=254, Percent_Identity=32.2834645669291, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17562990, Length=254, Percent_Identity=31.496062992126, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI71994604, Length=258, Percent_Identity=31.0077519379845, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17562906, Length=256, Percent_Identity=34.375, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI17559104, Length=255, Percent_Identity=32.9411764705882, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17560332, Length=255, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=30.5343511450382, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=31.6793893129771, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17562908, Length=256, Percent_Identity=33.203125, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI71994600, Length=259, Percent_Identity=30.1158301158301, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17538480, Length=259, Percent_Identity=30.8880308880309, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17531453, Length=260, Percent_Identity=33.0769230769231, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=28.2352941176471, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17568967, Length=210, Percent_Identity=29.5238095238095, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17538486, Length=255, Percent_Identity=30.9803921568627, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI17551412, Length=254, Percent_Identity=29.9212598425197, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17536651, Length=255, Percent_Identity=27.843137254902, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI193204405, Length=257, Percent_Identity=31.1284046692607, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17536025, Length=261, Percent_Identity=28.735632183908, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17563726, Length=252, Percent_Identity=27.7777777777778, Blast_Score=85, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17565030, Length=254, Percent_Identity=31.1023622047244, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI72000259, Length=255, Percent_Identity=30.1960784313725, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17560220, Length=256, Percent_Identity=28.125, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI115534694, Length=241, Percent_Identity=26.9709543568465, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=27.9850746268657, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17538182, Length=256, Percent_Identity=27.34375, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17561272, Length=224, Percent_Identity=27.2321428571429, Blast_Score=69, Evalue=3e-12, Organism=Saccharomyces cerevisiae, GI6322861, Length=220, Percent_Identity=29.5454545454545, Blast_Score=94, Evalue=3e-20, Organism=Saccharomyces cerevisiae, GI6324126, Length=248, Percent_Identity=23.7903225806452, Blast_Score=67, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6323882, Length=204, Percent_Identity=30.3921568627451, Blast_Score=63, Evalue=5e-11, Organism=Drosophila melanogaster, GI28571526, Length=239, Percent_Identity=35.9832635983264, Blast_Score=124, Evalue=7e-29, Organism=Drosophila melanogaster, GI21357041, Length=239, Percent_Identity=35.1464435146443, Blast_Score=122, Evalue=3e-28, Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=34.412955465587, Blast_Score=113, Evalue=1e-25, Organism=Drosophila melanogaster, GI24644339, Length=245, Percent_Identity=31.4285714285714, Blast_Score=110, Evalue=1e-24, Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=31.2, Blast_Score=106, Evalue=1e-23, Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=31.2, Blast_Score=104, Evalue=7e-23, Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=29.7959183673469, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI18859837, Length=244, Percent_Identity=29.5081967213115, Blast_Score=84, Evalue=7e-17, Organism=Drosophila melanogaster, GI24644337, Length=170, Percent_Identity=34.7058823529412, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI17737361, Length=259, Percent_Identity=28.1853281853282, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI24665243, Length=174, Percent_Identity=33.9080459770115, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI221331218, Length=174, Percent_Identity=33.9080459770115, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI24665247, Length=174, Percent_Identity=32.7586206896552, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI116007236, Length=194, Percent_Identity=26.8041237113402, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI221331216, Length=174, Percent_Identity=32.7586206896552, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24641232, Length=217, Percent_Identity=28.110599078341, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI116007238, Length=239, Percent_Identity=23.4309623430962, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI281364892, Length=163, Percent_Identity=30.6748466257669, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI28571387, Length=187, Percent_Identity=30.4812834224599, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 27551; Mature: 27420
Theoretical pI: Translated: 5.80; Mature: 5.80
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 1.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSLSEAPKEIAGHGLLEGKVVIVTAAAGTGIGSATAKRALAEGADVVISDHHERRLGETA CCCCCCCHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHH DQLAALGQGRVESVLCDVTSTAQVDALFASAHARMGRIDVLVNNAGLGGQTPVVDMTDDE HHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEECCCCH WDRVLDVTLTSVFRATRAALRYFRDAPHGGVIVNNASVLGWRAQHSQSHYAAAKAGVMAL HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEEHHCCCCHHHHHHHHHHHH TRCSAIEAAEYDVRINAVSPSIARHKFLEKTSSADLLDRLSAGEAFGRAAEPWEVAATIA HHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHCCHHHCCCCCCHHHHHHHH FLASDYSSYLTGEVISVSSQHP HHHHHHHHHHCCCEEECCCCCC >Mature Secondary Structure SLSEAPKEIAGHGLLEGKVVIVTAAAGTGIGSATAKRALAEGADVVISDHHERRLGETA CCCCCCHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHH DQLAALGQGRVESVLCDVTSTAQVDALFASAHARMGRIDVLVNNAGLGGQTPVVDMTDDE HHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEECCCCH WDRVLDVTLTSVFRATRAALRYFRDAPHGGVIVNNASVLGWRAQHSQSHYAAAKAGVMAL HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEEHHCCCCHHHHHHHHHHHH TRCSAIEAAEYDVRINAVSPSIARHKFLEKTSSADLLDRLSAGEAFGRAAEPWEVAATIA HHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHCCHHHCCCCCCHHHHHHHH FLASDYSSYLTGEVISVSSQHP HHHHHHHHHHCCCEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]